• 1018 Citations
  • 16 h-Index
20052019

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Article
2019

Serum d-serine accumulation after proximal renal tubular damage involves neutral amino acid transporter Asc-1

Suzuki, M., Gonda, Y., Yamada, M., Vandebroek, A. A., Mita, M., Hamase, K., Yasui, M. & Sasabe, J., 2019 Dec 1, In : Scientific reports. 9, 1, 16705.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2017

Deciphering the landscape of host barriers to Listeria monocytogenes infection

Zhang, T., Abel, S., Wiesch, P. A., Sasabe, J., Davis, B. M., Higgins, D. E. & Waldor, M. K., 2017 Jun 13, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 24, p. 6334-6339 6 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Heterogeneity of D-serine distribution in the human central nervous system

Suzuki, M., Imanishi, N., Mita, M., Hamase, K., Aiso, S. & Sasabe, J., 2017 May 1, In : ASN neuro. 9, 3

Research output: Contribution to journalArticle

13 Citations (Scopus)
2016

Chemoproteomic profiling of host and pathogen enzymes active in cholera

Hatzios, S. K., Abel, S., Martell, J., Hubbard, T., Sasabe, J., Munera, D., Clark, L., Bachovchin, D. A., Qadri, F., Ryan, E. T., Davis, B. M., Weerapana, E. & Waldor, M. K., 2016 Apr 1, In : Nature Chemical Biology. 12, 4, p. 268-274 7 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Interplay between microbial d-amino acids and host d-amino acid oxidase modifies murine mucosal defence and gut microbiota

Sasabe, J., Miyoshi, Y., Rakoff-Nahoum, S., Zhang, T., Mita, M., Davis, B. M., Hamase, K. & Waldor, M. K., 2016 Jul 25, In : Nature Microbiology. 1, 16125.

Research output: Contribution to journalArticle

42 Citations (Scopus)
2015

A genome-wide screen reveals that the Vibrio cholerae phosphoenolpyruvate phosphotransferase system modulates virulence gene expression

Wang, Q., Millet, Y. A., Chao, M. C., Sasabe, J., Davis, B. M. & Waldor, M. K., 2015, In : Infection and Immunity. 83, 9, p. 3381-3395 15 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Glycolytic flux controls D-serine synthesis through glyceraldehyde-3-phosphate dehydrogenase in astrocytes

Suzuki, M., Sasabe, J., Miyoshi, Y., Kuwasako, K., Muto, Y., Hamase, K., Matsuoka, M., Imanishi, N. & Aiso, S., 2015 Apr 28, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 17, p. E2217-E2224

Research output: Contribution to journalArticle

24 Citations (Scopus)

High-resolution genetic analysis of the requirements for horizontal transmission of the ESBL plasmid from Escherichia coli O104:H4

Yamaichi, Y., Chao, M. C., Sasabe, J., Clark, L., Davis, B. M., Yamamoto, N., Mori, H., Kurokawa, K. & Waldor, M. K., 2015, In : Nucleic acids research. 43, 1, p. 348-360 13 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)
2014

Activity of D-amino acid oxidase is widespread in the human central nervous system

Sasabe, J., Suzuki, M., Imanishi, N. & Aiso, S., 2014, In : Frontiers in Synaptic Neuroscience. 6, JUN, 14.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Cellular origin and regulation of D- and L-serine in in vitro and in vivo models of cerebral ischemia

Abe, T., Suzuki, M., Sasabe, J., Takahashi, S., Unekawa, M., Mashima, K., Iizumi, T., Hamase, K., Konno, R., Aiso, S. & Suzuki, N., 2014 Dec 1, In : Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 34, 12, p. 1928-1935 8 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Ischemic acute kidney injury perturbs homeostasis of serine enantiomers in the body fluid in mice: Early detection of renal dysfunction using the ratio of serine enantiomers

Sasabe, J., Suzuki, M., Miyoshi, Y., Tojo, Y., Okamura, C., Ito, S., Konno, R., Mita, M., Hamase, K. & Aiso, S., 2014 Jan 29, In : PloS one. 9, 1, e86504.

Research output: Contribution to journalArticle

31 Citations (Scopus)

PEGylated d-serine dehydratase as a d-serine reducing agent

Ito, T., Takada, H., Isobe, K., Suzuki, M., Kitaura, Y., Hemmi, H., Matsuda, T., Sasabe, J. & Yoshimura, T., 2014 Oct 9, In : Journal of Pharmaceutical and Biomedical Analysis. 116, p. 34-39 6 p.

Research output: Contribution to journalArticle

2012

Alteration of intrinsic amounts of D-serine in the mice lacking serine racemase and D-amino acid oxidase

Miyoshi, Y., Konno, R., Sasabe, J., Ueno, K., Tojo, Y., Mita, M., Aiso, S. & Hamase, K., 2012 Nov 1, In : Amino Acids. 43, 5, p. 1919-1931 13 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

D-Amino acid oxidase controls motoneuron degeneration through D-serine

Sasabe, J., Miyoshi, Y., Suzuki, M., Mita, M., Konno, R., Matsuoka, M., Hamase, K. & Aiso, S., 2012 Jan 10, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 2, p. 627-632 6 p.

Research output: Contribution to journalArticle

119 Citations (Scopus)

D-Ser-containing humanin shows promotion of fibril formation

Hayashi, K., Sasabe, J., Chiba, T., Aiso, S. & Utsunomiya-Tate, N., 2012 Jun, In : Amino Acids. 42, 6, p. 2293-2297 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Type 1 diabetes mellitus in mice increases hippocampal d-serine in the acute phase after streptozotocin injection

Suzuki, M., Sasabe, J., Furuya, S., Mita, M., Hamase, K. & Aiso, S., 2012 Jul 23, In : Brain Research. 1466, p. 167-176 10 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2010

D-Serine in the pathogenesis of amyotrophic lateral sclerosis

Sasabe, J. & Aiso, S., 2010 Dec 1, In : Seikagaku. 82, 7, p. 628-632 5 p.

Research output: Contribution to journalArticle

2009

Amyloid-β causes memory impairment by disturbing the JAK2/STAT3 axis in hippocampal neurons

Chiba, T., Yamada, M., Sasabe, J., Terashita, K., Shimoda, M., Matsuoka, M. & Aiso, S., 2009 Feb 1, In : Molecular Psychiatry. 14, 2, p. 206-222 17 p.

Research output: Contribution to journalArticle

127 Citations (Scopus)
2008

Nasal Colivelin treatment ameliorates memory impairment related to Alzheimer's disease

Yamada, M., Chiba, T., Sasabe, J., Terashita, K., Aiso, S. & Matsuoka, M., 2008 Jul 1, In : Neuropsychopharmacology. 33, 8, p. 2020-2032 13 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)
2007

D-Serine is a key determinant of glutamate toxicity in amyotrophic lateral sclerosis

Sasabe, J., Chiba, T., Yamada, M., Okamoto, K., Nishimoto, I., Matsuoka, M. & Aiso, S., 2007 Sep 19, In : EMBO Journal. 26, 18, p. 4149-4159 11 p.

Research output: Contribution to journalArticle

198 Citations (Scopus)
2006

Colivelin prolongs survival of an ALS model mouse

Chiba, T., Yamada, M., Sasabe, J., Terashita, K., Aiso, S., Matsuoka, M. & Nishimoto, I., 2006 May 12, In : Biochemical and Biophysical Research Communications. 343, 3, p. 793-798 6 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)
2005

A Rac1/phosphatidylinositol 3-kinase/Akt3 anti-apoptotic pathway, triggered by alsinLF, the product of the ALS2 gene, antagonizes Cu/Zn-superoxide dismutase (SOD1) mutant-induced motoneuronal cell death

Kanekura, K., Hashimoto, Y., Kita, Y., Sasabe, J., Aiso, S., Nishimoto, I. & Matsuoka, M., 2005 Feb 11, In : Journal of Biological Chemistry. 280, 6, p. 4532-4543 12 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)

Development of a femtomolar-acting humanin derivative named colivelin by attaching activity-dependent neurotrophic factor to its N terminus: Characterization of colivelin-mediated neuroprotection against Alzheimer's disease-relevant insults in vitro and in vivo

Chiba, T., Yamada, M., Hashimoto, Y., Sato, M., Sasabe, J., Kita, Y., Terashita, K., Aiso, S., Nishimoto, I. & Matsuoka, M., 2005 Nov 2, In : Journal of Neuroscience. 25, 44, p. 10252-10261 10 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)

Implanted cannula-mediated repetitive administration of Aβ25-35 into the mouse cerebral ventricle effectively impairs spatial working memory

Yamada, M., Chiba, T., Sasabe, J., Nawa, M., Tajima, H., Niikura, T., Terashita, K., Aiso, S., Kita, Y., Matsuoka, M. & Nishimoto, I., 2005 Nov 7, In : Behavioural Brain Research. 164, 2, p. 139-146 8 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)