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Research Output 2008 2019

  • 298 Citations
  • 10 h-Index
  • 19 Article
  • 3 Review article
  • 2 Editorial
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Article
2019
1 Citation (Scopus)

Decreased KAT5 Expression Impairs DNA Repair and Induces Altered DNA Methylation in Kidney Podocytes

Hishikawa, A., Hayashi, K., Abe, T., Kaneko, M., Yokoi, H., Azegami, T., Nakamura, M., Yoshimoto, N., Kanda, T., Sakamaki, Y. & Itoh, H., 2019 Jan 29, In : Cell Reports. 26, 5, p. 1318-1332.e4

Research output: Contribution to journalArticle

Podocytes
DNA Methylation
DNA Repair
Repair
Kidney
2018
7 Citations (Scopus)

Intranasal vaccination against angiotensin II type 1 receptor and pneumococcal surface protein A attenuates hypertension and pneumococcal infection in rodents

Azegami, T., Yuki, Y., Hayashi, K., Hishikawa, A., Sawada, S. I., Ishige, K., Akiyoshi, K., Kiyono, H. & Itoh, H., 2018 Feb 1, In : Journal of Hypertension. 36, 2, p. 387-394 8 p.

Research output: Contribution to journalArticle

Pneumococcal Infections
Angiotensin Type 1 Receptor
Inbred SHR Rats
Rodentia
Vaccination
1 Citation (Scopus)

Pre-emptive medicine for hypertension and its prospects

Itoh, H., Hayashi, K. & Miyashita, K., 2018 Jan 1, (Accepted/In press) In : Hypertension Research.

Research output: Contribution to journalArticle

Hypertension
Medicine
Disease Progression
Blood Pressure
Artificial Intelligence
2017
2 Citations (Scopus)
Cerebrovascular Disorders
Ultrasonography
Magnetic Resonance Imaging
Chronic Renal Insufficiency
Kidney
8 Citations (Scopus)
Glomerular Filtration Rate
Chronic Renal Insufficiency
Population
Kidney Diseases
Obesity
2015
27 Citations (Scopus)

Renin-angiotensin blockade resets podocyte epigenome through Kruppel-like Factor 4 and attenuates proteinuria

Hayashi, K., Sasamura, H., Nakamura, M., Sakamaki, Y., Azegami, T., Oguchi, H., Tokuyama, H., Wakino, S., Hayashi, K. & Itoh, H., 2015 Oct 3, In : Kidney International. 88, 4, p. 745-753 9 p.

Research output: Contribution to journalArticle

Podocytes
Angiotensins
Proteinuria
Renin
Angiotensin Receptor Antagonists
Therapeutic Uses
Renin-Angiotensin System
Epigenomics
Life Style
Podocytes
2014
57 Citations (Scopus)

KLF4-dependent epigenetic remodeling modulates podocyte phenotypes and attenuates proteinuria

Hayashi, K., Sasamura, H., Nakamura, M., Azegami, T., Oguchi, H., Sakamaki, Y. & Itoh, H., 2014 Jun 2, In : Journal of Clinical Investigation. 124, 6, p. 2523-2537 15 p.

Research output: Contribution to journalArticle

Podocytes
Proteinuria
Epigenomics
Phenotype
Doxorubicin
5 Citations (Scopus)

Renal arteriolar injury by salt intake contributes to salt memory for the development of hypertension

Oguchi, H., Sasamura, H., Shinoda, K., Morita, S., Kono, H., Nakagawa, K., Ishiguro, K., Hayashi, K., Nakamura, M., Azegami, T., Oya, M. & Itoh, H., 2014, In : Hypertension. 64, 4, p. 784-791 8 p.

Research output: Contribution to journalArticle

Salts
Hypertension
Kidney
Wounds and Injuries
Inbred Dahl Rats
5 Citations (Scopus)
Chronic Renal Insufficiency
Epigenomics
Transcription Factors
Podocytes
Therapeutics
2012
15 Citations (Scopus)
Angiotensin Receptor Antagonists
Apolipoproteins E
Atherosclerosis
Biglycan
Lipids
20 Citations (Scopus)

Vaccination against the angiotensin type 1 receptor for the prevention of L-NAME-induced nephropathy

Azegami, T., Sasamura, H., Hayashi, K. & Itoh, H., 2012 May, In : Hypertension Research. 35, 5, p. 492-499 8 p.

Research output: Contribution to journalArticle

Angiotensin Type 1 Receptor
NG-Nitroarginine Methyl Ester
Vaccination
Vaccines
Hydralazine
2011
20 Citations (Scopus)

Use of serum and urine metabolome analysis for the detection of metabolic changes in patients with stage 1-2 chronic kidney disease

Hayashi, K., Sasamura, H., Hishiki, T., Suematsu, M., Ikeda, S., Soga, T. & Itoh, H., 2011, In : Nephro-Urology Monthly. 3, 3, p. 164-171 8 p.

Research output: Contribution to journalArticle

Metabolome
Chronic Renal Insufficiency
Urine
Metabolomics
Serum
2010
14 Citations (Scopus)

Absence of gelatinase (MMP-9) or collagenase (MMP-13) attenuates adriamycin-Induced albuminuria and glomerulosclerosis

Sakamaki, Y., Sasamura, H., Hayashi, K., Ishiguro, K., Takaishi, H., Okada, Y., D'Armiento, J. M., Saruta, T. & Itoh, H., 2010 Jun, In : Nephron - Experimental Nephrology. 115, 2

Research output: Contribution to journalArticle

Matrix Metalloproteinase 13
Gelatinases
Albuminuria
Matrix Metalloproteinase 9
Collagenases
34 Citations (Scopus)

Regression of glomerulosclerosis in response to transient treatment with angiotensin II blockers is attenuated by blockade of matrix metalloproteinase-2

Hayashi, K., Sasamura, H., Ishiguro, K., Sakamaki, Y., Azegami, T. & Itoh, H., 2010 Jul, In : Kidney International. 78, 1, p. 69-78 10 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 2
Angiotensin II
Angiotensin Receptor Antagonists
Therapeutics
Podocytes
2009
30 Citations (Scopus)

Activation of dendritic-like cells and neural stem/progenitor cells in injured spinal cord by GM-CSF

Hayashi, K., Ota, S., Kawakami, Y. & Toda, M., 2009 May, In : Neuroscience Research. 64, 1, p. 96-103 8 p.

Research output: Contribution to journalArticle

Neural Stem Cells
Granulocyte-Macrophage Colony-Stimulating Factor
Dendritic Cells
Spinal Cord
Stem Cells
15 Citations (Scopus)

Prevention and regression of hypertension: Role of renal microvascular protection

Sasamura, H., Hayashi, K., Ishiguro, K., Nakaya, H., Saruta, T. & Itoh, H., 2009, In : Hypertension Research. 32, 8, p. 658-664 7 p.

Research output: Contribution to journalArticle

Renal Hypertension
Hypertension
Angiotensin Receptor Antagonists
Inbred SHR Rats
Kidney
22 Citations (Scopus)

"Pulse" treatment with high-dose angiotensin blocker reverses renal arteriolar hypertrophy and regresses hypertension

Ishiguro, K., Hayashi, K., Sasamura, H., Sakamaki, Y. & Itoh, H., 2009 Jan, In : Hypertension. 53, 1, p. 83-89 7 p.

Research output: Contribution to journalArticle

Angiotensin Receptor Antagonists
Angiotensins
Inbred SHR Rats
Hypertrophy
Calcium Channel Blockers
2008
7 Citations (Scopus)
Angiotensin Receptor Antagonists
Diabetic Nephropathies
Inbred SHR Rats
Mineralocorticoid Receptor Antagonists
Antihypertensive Agents