• 10215 Citations
  • 48 h-Index
1990 …2020

Research output per year

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Research Output

2020

Neuron-derived VEGF contributes to cortical and hippocampal development independently of VEGFR1/2-mediated neurotrophism

Okabe, K., Fukada, H., Tai-Nagara, I., Ando, T., Honda, T., Nakajima, K., Takeda, N., Fong, G. H., Ema, M. & Kubota, Y., 2020 Mar 15, In : Developmental Biology. 459, 2, p. 65-71 7 p.

Research output: Contribution to journalArticle

Open Access

Two-Photon Voltage Imaging of Spontaneous Activity from Multiple Neurons Reveals Network Activity in Brain Tissue

Li, B., Chavarha, M., Kobayashi, Y., Yoshinaga, S., Nakajima, K., Lin, M. Z. & Inoue, T., 2020 Aug 21, In : iScience. 23, 8, 101363.

Research output: Contribution to journalArticle

Open Access
Open Access
2019

Both excitatory and inhibitory neurons transiently form clusters at the outermost region of the developing mammalian cerebral neocortex

Shin, M., Kitazawa, A., Yoshinaga, S., Hayashi, K., Hirata, Y., Dehay, C., Kubo, K. & Nakajima, K., 2019 Jan 1, In : Journal of Comparative Neurology.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Drebrin-like (Dbnl) controls neuronal migration via regulating N-cadherin expression in the developing cerebral cortex

Inoue, S., Hayashi, K., Fujita, K., Tagawa, K., Okazawa, H., Kubo, K. I. & Nakajima, K., 2019 Jan 23, In : Journal of Neuroscience. 39, 4, p. 678-691 14 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Role of the Immune System in the Development of the Central Nervous System

Morimoto, K. & Nakajima, K., 2019 Sep 3, In : Frontiers in Neuroscience. 13, 916.

Research output: Contribution to journalReview article

Open Access
10 Citations (Scopus)

Timing and shaping mechanisms of neural development

Kageyama, R. & Nakajima, K., 2019 Jan 1, In : Neuroscience Research. 138, p. 1-2 2 p.

Research output: Contribution to journalEditorial

2018

ApoER2 Controls not only neuronal migration in the intermediate zone but also termination of migration in the developing cerebral cortex

Hirota, Y., Kubo, K. I., Fujino, T., Yamamoto, T. T. & Nakajima, K., 2018 Jan 1, In : Cerebral Cortex. 28, 1, p. 223-235 13 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2017

A crossroad of neuronal diversity to build circuitry

Yoshinaga, S. & Nakajima, K., 2017 Apr 28, In : Science. 356, 6336, p. 376-377 2 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Association of impaired neuronal migration with cognitive deficits in extremely preterm infants

Kubo, K. I., Deguchi, K., Nagai, T., Ito, Y., Yoshida, K., Endo, T., Benner, S., Shan, W., Kitazawa, A., Aramaki, M., Ishii, K., Shin, M., Matsunaga, Y., Hayashi, K., Kakeyama, M., Tohyama, C., Tanaka, K. F., Tanaka, K., Takashima, S., Nakayama, M. & 7 others, Itoh, M., Hirata, Y., Antalffy, B., Armstrong, D. D., Yamada, K., Inoue, K. & Nakajima, K., 2017 May 18, In : JCI Insight. 2, 10

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)

CHARGE syndrome modeling using patient-iPSCs reveals defective migration of neural crest cells harboring CHD7 mutations

Okuno, H., Mihara, F. R., Ohta, S., Fukuda, K., Kurosawa, K., Akamatsu, W., Sanosaka, T., Kohyama, J., Hayashi, K., Nakajima, K., Takahashi, T., Wysocka, J., Kosaki, K. & Okano, H., 2017 Nov 28, In : eLife. 6, e21114.

Research output: Contribution to journalArticle

18 Citations (Scopus)
19 Citations (Scopus)

Dendritic Homeostasis Disruption in a Novel Frontotemporal Dementia Mouse Model Expressing Cytoplasmic Fused in Sarcoma

Shiihashi, G., Ito, D., Arai, I., Kobayashi, Y., Hayashi, K., Otsuka, S., Nakajima, K., Yuzaki, M., Itohara, S. & Suzuki, N., 2017 Oct, In : EBioMedicine. 24, p. 102-115 14 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Enhanced expression of Pafah1b1 causes over-migration of cerebral cortical neurons into the marginal zone

Katayama, K. I., Hayashi, K., Inoue, S., Sakaguchi, K. & Nakajima, K., 2017 Aug 23, (Accepted/In press) In : Brain Structure and Function. p. 1-9 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Excessive activation of AhR signaling disrupts neuronal migration in the hippocampal CA1 region in the developing mouse

Kimura, E., Kubo, K. I., Endo, T., Nakajima, K., Kakeyama, M. & Tohyama, C., 2017, In : Journal of Toxicological Sciences. 42, 1, p. 25-30 6 p.

Research output: Contribution to journalLetter

10 Citations (Scopus)

Impaired dendritic growth and positioning of cortical pyramidal neurons by activation of aryl hydrocarbon receptor signaling in the developing mouse

Kimura, E., Kubo, K. I., Endo, T., Ling, W., Nakajima, K., Kakeyama, M. & Tohyama, C., 2017 Aug, In : PloS one. 12, 8, e0183497.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Reelin transiently promotes N-cadherin-dependent neuronal adhesion during mouse cortical development

Matsunaga, Y., Noda, M., Murakawa, H., Hayashi, K., Nagasaka, A., Inoue, S., Miyata, T., Miura, T., Kubo, K. I. & Nakajima, K., 2017 Feb 21, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 8, p. 2048-2053 6 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Subtype Specification of Cerebral Cortical Neurons in Their Immature Stages

Oishi, K. & Nakajima, K., 2017 Nov 28, (Accepted/In press) In : Neurochemical Research. p. 1-7 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2016

ADP ribosylation factor 6 regulates neuronal migration in the developing cerebral cortex through FIP3/arfophilin-1-dependent endosomal trafficking of N-cadherin

Hara, Y., Fukaya, M., Hayashi, K., Kawauchi, T., Nakajima, K. & Sakagami, H., 2016, In : eNeuro. 3, 4, e0148-16.2016.

Research output: Contribution to journalArticle

18 Citations (Scopus)

DISC1 a key molecular lead in psychiatry and neurodevelopment: No-More Disrupted-in-Schizophrenia 1

Niwa, M., Cash-Padgett, T., Kubo, K. I., Saito, A., Ishii, K., Sumitomo, A., Taniguchi, Y., Ishizuka, K., Jaaro-Peled, H., Tomoda, T., Nakajima, K., Sawa, A. & Kamiya, A., 2016 Nov 1, In : Molecular Psychiatry. 21, 11, p. 1488-1489 2 p.

Research output: Contribution to journalComment/debate

38 Citations (Scopus)

Identity of neocortical layer 4 neurons is specified through correct positioning into the cortex

Oishi, K., Nakagawa, N., Tachikawa, K., Sasaki, S., Aramaki, M., Hirano, S., Yamamoto, N., Yoshimura, Y. & Nakajima, K., 2016 Feb 12, In : eLife. 5, FEBRUARY2016, e10907.

Research output: Contribution to journalArticle

19 Citations (Scopus)

In utero bisphenol A exposure induces abnormal neuronal migration in the cerebral cortex of mice

Ling, W., Endo, T., Kubo, K. I., Nakajima, K., Kakeyama, M. & Tohyama, C., 2016, In : Frontiers in Endocrinology. 7, FEB, 7.

Research output: Contribution to journalArticle

4 Citations (Scopus)
17 Citations (Scopus)

PDK1-Akt pathway regulates radial neuronal migration and microtubules in the developing mouse neocortex

Itoh, Y., Higuchi, M., Oishi, K., Kishi, Y., Okazaki, T., Sakai, H., Miyata, T., Nakajima, K. & Gotoh, Y., 2016 May 24, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 21, p. E2955-E2964

Research output: Contribution to journalArticle

26 Citations (Scopus)
9 Citations (Scopus)

Reelin and neuropsychiatric disorders

Ishii, K., Kubo, K. I. & Nakajima, K., 2016 Oct 18, In : Frontiers in Cellular Neuroscience. 10, OCT2016, 229.

Research output: Contribution to journalReview article

53 Citations (Scopus)

Role of reelin during layer formation in the cerebralneocortex

Nakajima, K., 2016 Aug, In : Brain and Nerve. 68, 8, p. 931-937 7 p.

Research output: Contribution to journalReview article

The mitotic tensegrity guardian tau protects mammary epithelia from katanin-like1-induced aneuploidy

Sudo, H. & Nakajima, K., 2016 Aug 1, In : Oncotarget. 7, 33, p. 53712-53734 23 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2015

Analysis of cardiomyocyte movement in the developing murine heart

Hashimoto, H., Yuasa, S., Tabata, H., Tohyama, S., Seki, T., Egashira, T., Hayashiji, N., Hattori, F., Kusumoto, D., Kunitomi, A., Takei, M., Kashimura, S., Yozu, G., Shimojima, M., Motoda, C., Muraoka, N., Nakajima, K., Sakaue-Sawano, A., Miyawaki, A. & Fukuda, K., 2015 Sep 4, In : Biochemical and Biophysical Research Communications. 464, 4, p. 1000-1007 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Cdk5 phosphorylation of ErbB4 is required for tangential migration of cortical interneurons

Rakić, S., Kanatani, S., Hunt, D., Faux, C., Cariboni, A., Chiara, F., Khan, S., Wansbury, O., Howard, B., Nakajima, K., Nikolić, M. & Parnavelas, J. G., 2015 Apr 1, In : Cerebral Cortex. 25, 4, p. 991-1003 13 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Cellular dynamics of neuronal migration in the hippocampus

Hayashi, K., Kubo, K. I., Kitazawa, A. & Nakajima, K., 2015, In : Frontiers in Neuroscience. 9, APR, 135.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Characterization of the dipeptide repeat protein in the molecular pathogenesis of c9FTD/ALS

Yamakawa, M., Ito, D., Honda, T., Kubo, K., Noda, M., Nakajima, K. & Suzuki, N., 2015, In : Human Molecular Genetics. 24, 6, p. 1630-1645 16 p., ddu576.

Research output: Contribution to journalArticle

80 Citations (Scopus)

Developmental origin of abnormal dendritic growth in the mouse brain induced by in utero disruption of aryl hydrocarbon receptor signaling

Kimura, E., Kubo, K. I., Matsuyoshi, C., Benner, S., Hosokawa, M., Endo, T., Ling, W., Kohda, M., Yokoyama, K., Nakajima, K., Kakeyama, M. & Tohyama, C., 2015 Nov 1, In : Neurotoxicology and Teratology. 52, p. 42-50 9 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Importance of reelin C-terminal region in the development and maintenance of the postnatal cerebral cortex and its regulation by specific proteolysis

Kohno, T., Honda, T., Kubo, K. I., Nakano, Y., Tsuchiya, A., Murakami, T., Banno, H., Nakajima, K. & Hattori, M., 2015, In : Journal of Neuroscience. 35, 11, p. 4776-4787 12 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Neuronal heterotopias affect the activities of distant brain areas and lead to behavioral deficits

Ishii, K., Kubo, K. I., Endo, T., Yoshida, K., Benner, S., Ito, Y., Aizawa, H., Aramaki, M., Yamanaka, A., Tanaka, K., Takata, N., Tanaka, K. F., Mimura, M., Tohyama, C., Kakeyama, M. & Nakajima, K., 2015 Sep 9, In : Journal of Neuroscience. 35, 36, p. 12432-12445 14 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Reelin has a preventive effect on phencyclidine-induced cognitive and sensory-motor gating deficits

Ishii, K., Nagai, T., Hirota, Y., Noda, M., Nabeshima, T., Yamada, K., Kubo, K. I. & Nakajima, K., 2015 Jul 1, In : Neuroscience Research. 96, p. 30-36 7 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Reelin receptors ApoER2 and VLDLR are expressed in distinct spatiotemporal patterns in developing mouse cerebral cortex

Hirota, Y., Kubo, K. I., Katayama, K. I., Honda, T., Fujino, T., Yamamoto, T. T. & Nakajima, K., 2015 Feb 15, In : Journal of Comparative Neurology. 523, 3, p. 463-478 16 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

The COUP-TFII/neuropilin-2 is a molecular switch steering diencephalon-derived GABAergic neurons in the developing mouse brain

Kanatani, S., Honda, T., Aramaki, M., Hayashi, K., Kubo, K. I., Ishida, M., Tanaka, D. H., Kawauchi, T., Sekine, K., Kusuzawa, S., Kawasaki, T., Hirata, T., Tabata, H., Uhlén, P. & Nakajima, K., 2015 Sep 8, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 36, p. E4985-E4994

Research output: Contribution to journalArticle

12 Citations (Scopus)
2014

Cdk5 and its substrates, Dcx and p27kip1, regulate cytoplasmic dilation formation and nuclear elongation in migrating neurons

Nishimura, Y. V., Shikanai, M., Hoshino, M., Ohshima, T., Nabeshima, Y. I., Mizutani, K. I., Nagata, K. I., Nakajima, K. & Kawauchi, T., 2014 Sep, In : Development (Cambridge). 141, 18, p. 3540-3550 11 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Hippocampal pyramidal neurons switch from a multipolar migration mode to a novel "climbing" migration mode during development

Kitazawa, A., Kubo, K. I., Hayashi, K., Matsunaga, Y., Ishii, K. & Nakajima, K., 2014, In : Journal of Neuroscience. 34, 4, p. 1115-1126 12 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

How does Reelin control neuronal migration and layer formation in the developing mammalian neocortex?

Sekine, K., Kubo, K. I. & Nakajima, K., 2014 Sep 1, In : Neuroscience Research. 86, p. 50-58 9 p.

Research output: Contribution to journalReview article

70 Citations (Scopus)

Time-lapse imaging of cell cycle dynamics during development in living cardiomyocyte

Hashimoto, H., Yuasa, S., Tabata, H., Tohyama, S., Hayashiji, N., Hattori, F., Muraoka, N., Egashira, T., Okata, S., Yae, K., Seki, T., Nishiyama, T., Nakajima, K., Sakaue-Sawano, A., Miyawaki, A. & Fukuda, K., 2014 Jul, In : Journal of Molecular and Cellular Cardiology. 72, p. 241-249 9 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2013

[Results of a questionnaire on efforts to increase research-oriented doctors].

Yaginuma, H., Matsumura, G., Mori, C., Maeda, T., Araki, N., Noda, Y., Nakajima, K., Kawata, M., Okabe, S. & working group for the future planning of the Japanese Association of Anatomists, G. F. T. F. P. O. T. J. A. O. A., 2013 Mar, In : Unknown Journal. 88, 1-2, p. 3-8 6 p.

Research output: Contribution to journalReview article

Axon guidance mechanisms for establishment of callosal connections

Nishikimi, M., Oishi, K. & Nakajima, K., 2013 Jan 1, In : Neural plasticity. 2013, 149060.

Research output: Contribution to journalReview article

16 Citations (Scopus)

Cell Polarity and Initiation of Migration

Sekine, K., Tabata, H. & Nakajima, K., 2013 Aug 29, Cellular Migration and Formation of Neuronal Connections. Elsevier Inc., p. 231-244 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

6 Citations (Scopus)

Dab1-mediated colocalization of multi-adaptor protein CIN85 with Reelin receptors, ApoER2 and VLDLR, in neurons

Fuchigami, T., Sato, Y., Tomita, Y., Takano, T., Miyauchi, S. Y., Tsuchiya, Y., Saito, T., Kubo, K. I., Nakajima, K., Fukuda, M., Hattori, M. & Hisanaga, S. I., 2013 May 1, In : Genes to Cells. 18, 5, p. 410-424 15 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

DISC1: A key lead in studying cortical development and associated brain disorders

Narayan, S., Nakajima, K. & Sawa, A., 2013 Oct, In : Neuroscientist. 19, 5, p. 451-464 14 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Neuronal distribution in the cerebral cortex and its significance in schizophrenia

Kubo, K. I. & Nakajima, K., 2013 Oct 1, In : Brain and Nerve. 65, 10, p. 1133-1145 13 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)

Robo1 regulates the migration and laminar distribution of upper-layer pyramidal neurons of the cerebral cortex

Gonda, Y., Andrews, W. D., Tabata, H., Namba, T., Parnavelas, J. G., Nakajima, K., Kohsaka, S., Hanashima, C. & Uchino, S., 2013 Jun, In : Cerebral Cortex. 23, 6, p. 1495-1508 14 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

RP58 Regulates the Multipolar-Bipolar Transition of Newborn Neurons in the Developing Cerebral Cortex

Ohtaka-Maruyama, C., Hirai, S., Miwa, A., Heng, J. I. T., Shitara, H., Ishii, R., Taya, C., Kawano, H., Kasai, M., Nakajima, K. & Okado, H., 2013 Feb 8, In : Cell Reports. 3, 2, p. 458-471 14 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)