• 323 Citations
  • 9 h-Index
20092020

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(-)-Benzyl 2,3-dideoxy-β-d-erythro-hex-2-enopyranoside

Ohba, S., Okazaki, H., Ueda, Y., Hanaya, K., Shoji, M. & Sugai, T., 2013 Dec 1, In : Acta Crystallographica Section E: Structure Reports Online. 69, 12, p. o1811

Research output: Contribution to journalArticle

2 Citations (Scopus)
7 Citations (Scopus)
13 Citations (Scopus)

A Vinylogous Photocleavage Strategy Allows Direct Photocaging of Backbone Amide Structure

Mangubat-Medina, A. E., Martin, S. C., Hanaya, K. & Ball, Z. T., 2018 Jul 11, In : Journal of the American Chemical Society. 140, 27, p. 8401-8404 4 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Chemoenzymatic approaches to the synthesis of the (1S,2R)-isomer of benzyl 2-hydroxycyclohexanecarboxylate

Tsunekawa, R., Hanaya, K., Higashibayashi, S., Shoji, M. & Sugai, T., 2018 Jan 1, In : Molecular Catalysis. 444, p. 84-89 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Chemo-enzymatic enantioconvergent approach toward ethyl shikimate from ethyl 5-hydroxy-3,4-isopropylidenedioxycyclohex-1-enecarboxylate

Yamashita, Y., Hanaya, K., Sugai, T., Mizushima, T. & Shoji, M., 2013 Aug 5, In : Tetrahedron. 69, 31, p. 6527-6532 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
5 Citations (Scopus)
2 Citations (Scopus)

Chemo-enzymatic transformation of naturally abundant naringin to luteolin, a flavonoid with various biological effects

Kobayashi, R., Itou, T., Hanaya, K., Shoji, M., Hada, N. & Sugai, T., 2013 Aug 1, In : Journal of Molecular Catalysis B: Enzymatic. 92, p. 14-18 5 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Comprehensive semisyntheses of catathelasmols C, D, and E from D-glutamic acid, utilizing lipase-catalyzed site-selective reactions on intermediates

Hashiba, R., Hashimoto, R., Nishiguchi, M., Kobayashi, T., Hanaya, K., Higashibayashi, S. & Sugai, T., 2020 Jan 1, (Accepted/In press) In : Bioscience, Biotechnology and Biochemistry.

Research output: Contribution to journalArticle

Construction of 2,6,9,11-tetraoxatricyclo[6.2.1.03,8]undecane containing 4-keto-D-glucose skeleton

Fujitani, B., Hanaya, K., Higashibayashi, S., Shoji, M. & Sugai, T., 2017 Dec 21, In : Tetrahedron. 73, 51, p. 7217-7222 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Dearomative Oxidative Rearrangement of [3]Cyclo-1,8-carbazolylene

Yasui, M., Ohtsu, H., Kawano, M., Hanaya, K., Sugai, T. & Higashibayashi, S., 2018 Jan 1, In : Chemistry Letters. 47, 11, p. 1357-1359 3 p.

Research output: Contribution to journalArticle

Design, synthesis and photochemical reactivation of caged prodrugs of 8-hydroxyquinoline-based enzyme inhibitors

Ariyasu, S., Mizuseda, Y., Hanaya, K. & Aoki, S., 2014 Jul, In : Chemical and Pharmaceutical Bulletin. 62, 7, p. 642-648 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Design and synthesis of 8-hydroxyquinoline-based radioprotective agents

Ariyasu, S., Sawa, A., Morita, A., Hanaya, K., Hoshi, M., Takahashi, I., Wang, B. & Aoki, S., 2014 Aug 1, In : Bioorganic and Medicinal Chemistry. 22, 15, p. 3891-3905 15 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
20 Citations (Scopus)

Design and synthesis of photocleavable biotinylated-dopamine with polyethyleneoxy photocleavable linkers

Hanaya, K., Kageyama, Y., Kitamura, M. & Aoki, S., 2010 Feb 28, In : Heterocycles. 82, 2, p. 1601-1615 15 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Development of a novel sulfonate ester-based prodrug strategy

Hanaya, K., Yoshioka, S., Ariyasu, S., Aoki, S., Shoji, M. & Sugai, T., 2015 Sep 24, (Accepted/In press) In : Bioorganic and Medicinal Chemistry Letters.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Development of a sensitive LC–MS/MS method for quantification of linezolid and its primary metabolites in human serum

Souza, E., Felton, J., Crass, R. L., Hanaya, K. & Pai, M. P., 2020 Jan 30, In : Journal of Pharmaceutical and Biomedical Analysis. 178, 112968.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Divergent synthesis of pseudoenantiomers for ABC-ring moiety of steroids

Furuta, M., Hanaya, K., Sugai, T. & Shoji, M., 2014 May 14, In : Tetrahedron Letters. 55, 20, p. 3189-3191 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Evaluation of Zinc (II) chelators for inhibiting p53-mediated apoptosis

Morita, A., Ariyasu, S., Ohya, S., Takahashi, I., Wang, B., Tanaka, K., Uchida, T., Okazaki, H., Hanaya, K., Enomoto, A., Nenoi, M., Ikekita, M., Aoki, S. & Hosoi, Y., 2013 Dec, In : Oncotarget. 4, 12, p. 2439-2450 12 p.

Research output: Contribution to journalArticle

Open Access
16 Citations (Scopus)

Ex Situ Enantioconvergent Approaches for the Effective Use of Undesired­ Isomers: Stereochemical Convergence of a Substrate with Multiple Chiral Centers and Recycling of a Decarboxylated Byproduct

Yamashita, Y., Kurihara, T., Horiguchi, T., Miki, A., Shoji, M., Sugai, T. & Hanaya, K., 2016 Mar 16, (Accepted/In press) In : Synthesis (Germany).

Research output: Contribution to journalArticle

2 Citations (Scopus)

Formal synthesis of englerin A utilizing regio- and diastereoselective [4+3] cycloaddition

Hagihara, S., Hanaya, K., Sugai, T. & Shoji, M., 2018 Feb 1, In : Journal of Antibiotics. 71, 2, p. 257-262 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Formal total synthesis of (-)-hamigeran B from a chemo-enzymatically prepared building block with quaternary chiral center

Kuwata, K., Fujita, R., Hanaya, K., Higashibayashi, S. & Sugai, T., 2018 Jan 1, (Accepted/In press) In : Tetrahedron.

Research output: Contribution to journalArticle

4 Citations (Scopus)
1 Citation (Scopus)
5 Citations (Scopus)

Nickel(II)-Promoted Amide N-H Arylation of Pyroglutamate-Histidine with Arylboronic Acid Reagents

Hanaya, K., Miller, M. K. & Ball, Z. T., 2019 Jan 1, In : Organic Letters.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Photochemical cleavage reaction of 8-quinolinyl sulfonates that are halogenated and nitrated at the 7-position

Ariyasu, S., Hanaya, K., Tsunoda, M., Kitamura, M., Hayase, M., Abe, R. & Aoki, S., 2011 Nov 1, In : Chemical and Pharmaceutical Bulletin. 59, 11, p. 1355-1362 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
13 Citations (Scopus)

Rapid nickel(ii)-promoted cysteine: S -arylation with arylboronic acids

Hanaya, K., Ohata, J., Miller, M. K., Mangubat-Medina, A. E., Swierczynski, M. J., Yang, D. C., Rosenthal, R. M., Popp, B. V. & Ball, Z. T., 2019 Jan 1, In : Chemical Communications. 55, 19, p. 2841-2844 4 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
6 Citations (Scopus)
1 Citation (Scopus)

Reduction of acetophenones with methyl fluorines and a bulky group on the aromatic ring using microorganisms and related enzymes

Abe, C., Sugawara, T., MacHida, T., Higashi, T., Hanaya, K., Shoji, M., Cao, C., Yamamoto, T., Matsuda, T. & Sugai, T., 2012 Oct 1, In : Journal of Molecular Catalysis B: Enzymatic. 82, p. 86-91 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Selective capture and collection of live target cells using a photoreactive silicon wafer device modified with antibodies via a photocleavable linker

Ariyasu, S., Hanaya, K., Watanabe, E., Suzuki, T., Horie, K., Hayase, M., Abe, R. & Aoki, S., 2012 Sep 11, In : Langmuir. 28, 36, p. 13118-13126 9 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Short-step syntheses of naturally occurring polyoxygenated aromatics based on site-selective transformation

Yamashita, Y., Biard, A., Hanaya, K., Shoji, M. & Sugai, T., 2017 Jan 1, In : Bioscience, Biotechnology and Biochemistry. 81, 7, p. 1279-1284 6 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
9 Citations (Scopus)

Site-selective synthesis of acacetin and genkwanin through lipase-catalyzed deacetylation of apigenin 5,7-diacetate and subsequent methylation

Fujita, R., Mandal, S., Hanaya, K., Shoji, M., Higashibayashi, S. & Sugai, T., 2019 Jan 1, In : Heterocycles. 99, 1, p. 638-648 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Stereoselective synthesis of scyphostatin hydrophilic moiety

Kuwata, K., Suzuki, M., Inami, Y., Hanaya, K., Sugai, T. & Shoji, M., 2014 Apr 23, In : Tetrahedron Letters. 55, 17, p. 2856-2858 3 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Structure-activity relationship of celecoxib and rofecoxib for the membrane permeabilizing activity

Yamakawa, N., Suzuki, K., Yamashita, Y., Katsu, T., Hanaya, K., Shoji, M., Sugai, T. & Mizushima, T., 2014 Apr 15, In : Bioorganic and Medicinal Chemistry. 22, 8, p. 2529-2534 6 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Syntheses of Englerin A, a Potent Renal Cancer Inhibitor

Hagihara, S., Hanaya, K., Sugai, T. & Shoji, M., 2018 Jan 1, (Accepted/In press) In : Asian Journal of Organic Chemistry.

Research output: Contribution to journalArticle

1 Citation (Scopus)
Open Access

Synthesis and biological comparison of enantiomers of mepenzolate bromide, a muscarinic receptor antagonist with bronchodilatory and anti-inflammatory activities

Yamashita, Y., Tanaka, K. I., Asano, T., Yamakawa, N., Kobayashi, D., Ishihara, T., Hanaya, K., Shoji, M., Sugai, T., Wada, M., Mashimo, T., Fukunishi, Y. & Mizushima, T., 2014 Jul 1, In : Bioorganic and Medicinal Chemistry. 22, 13, p. 3488-3497 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
1 Citation (Scopus)
1 Citation (Scopus)
13 Citations (Scopus)

Synthesis of benzyl tetra-O-acetyl-α-L-glucopyranoside from benzyl 2,3-dideoxy-β-D-Erythro-hex-2-enopyranoside

Okazaki, H., Ueda, Y., Hanaya, K., Shoji, M. & Sugai, T., 2017, In : Heterocycles. 95, 2, p. 862-871 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Synthesis of enantiomerically enriched drug precursors and an insect pheromone via reduction of ketones using commercially available carbonyl reductase screening kit "Chiralscreen® OH"

Nagai, T., Sakurai, S., Natori, N., Hataoka, M., Kinoshita, T., Inoue, H., Hanaya, K., Shoji, M. & Sugai, T., 2017 Jan 14, (Accepted/In press) In : Bioorganic and Medicinal Chemistry.

Research output: Contribution to journalArticle

7 Citations (Scopus)
4 Citations (Scopus)
1 Citation (Scopus)