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Fingerprint Dive into the research topics where Kyoko Takahashi is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 3 Similar Profiles
Fullerenes Chemical Compounds
Derivatives Chemical Compounds
Benzbromarone Medicine & Life Sciences
Ajuga Medicine & Life Sciences
Antioxidants Medicine & Life Sciences
Viruses Chemical Compounds
Scavenging Chemical Compounds
Hepacivirus Medicine & Life Sciences

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Research Output 2000 2019

  • 656 Citations
  • 12 h-Index
  • 26 Article
  • 2 Review article
  • 1 Chapter

Synthesis and antitumor activity of novel pyridinium fullerene derivatives

Yasuno, T., Ohe, T., Ikeda, H., Takahashi, K., Nakamura, S. & Mashino, T., 2019 Jan 1, In : International journal of nanomedicine. 14, p. 6325-6337 13 p.

Research output: Contribution to journalArticle

Open Access
Fullerenes
Derivatives
Heterografts
Cell Line
Lead compounds
2 Citations (Scopus)

A 5-hydroxyoxindole derivative attenuates LPS-induced inflammatory responses by activating the p38-Nrf2 signaling axis

Niino, T., Tago, K., Yasuda, D., Takahashi, K., Mashino, T., Tamura, H. & Tago, M., 2018 Sep 1, In : Biochemical Pharmacology. 155, p. 182-197 16 p.

Research output: Contribution to journalArticle

Derivatives
Acetylcysteine
Cysteine
Chemical activation
Antioxidants

Hit-to-Lead in Academia: Discovery of a Protein-Protein Interaction Inhibitor of Keap1-Nrf2

Yasuda, D., Obata, R., Takahashi, K., Ohe, T. & Mashino, T., 2018 Jan 1, In : Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 138, 8, p. 1059-1065 7 p.

Research output: Contribution to journalReview article

Proteins
Drug Discovery
Kelch-Like ECH-Associated Protein 1
Lead
Protein Stability

Synthesis of novel benzbromarone derivatives designed to avoid metabolic activation

Ohe, T., Umezawa, R., Kitagawara, Y., Yasuda, D., Takahashi, K., Nakamura, S., Abe, A., Sekine, S., Ito, K., Okunushi, K., Morio, H., Furihata, T., Anzai, N. & Mashino, T., 2018 Jan 1, (Accepted/In press) In : Bioorganic and Medicinal Chemistry Letters.

Research output: Contribution to journalArticle

Benzbromarone
Uricosuric Agents
Chemical activation
Derivatives
Uric Acid
7 Citations (Scopus)

Discovery of benzo[g]indoles as a novel class of non-covalent Keap1-Nrf2 protein-protein interaction inhibitor

Yasuda, D., Yuasa, A., Obata, R., Nakajima, M., Takahashi, K., Ohe, T., Ichimura, Y., Komatsu, M., Yamamoto, M., Imamura, R., Kojima, H., Okabe, T., Nagano, T. & Mashino, T., 2017 Nov 15, In : Bioorganic and Medicinal Chemistry Letters. 27, 22, p. 5006-5009 4 p.

Research output: Contribution to journalArticle

Indoles
Proteins
Hydroxamic Acids
Lead compounds
Derivatives