• 1459 Citations
  • 18 h-Index
20012020

Research output per year

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Research Output

  • 1459 Citations
  • 18 h-Index
  • 78 Article
  • 4 Comment/debate
  • 2 Letter
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Article
2019

Airway M Cells arise in the lower airway due to RANKL signaling and reside in the bronchiolar epithelium associated with iBALT in murine models of respiratory disease

Kimura, S., Mutoh, M., Hisamoto, M., Saito, H., Takahashi, S., Asakura, T., Ishii, M., Nakamura, Y., Iida, J., Hase, K. & Iwanaga, T., 2019 Jan 1, In : Frontiers in Immunology. 10, JUN, 1323.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Black pleural effusion caused by pancreatic pseudocyst rupture

Ishigaki, S., Kuwae, M., Ishii, M., Asakura, T., Ueda, S. & Betsuyaku, T., 2019 Feb 1, In : Clinical Case Reports. 7, 2, p. 385-386 2 p.

Research output: Contribution to journalArticle

Open Access

Calorie restriction enhances adult mouse lung stem cells function and reverses several ageing-induced changes

Hegab, A. E., Ozaki, M., Meligy, F. Y., Nishino, M., Kagawa, S., Ishii, M. & Betsuyaku, T., 2019 Feb 1, In : Journal of Tissue Engineering and Regenerative Medicine. 13, 2, p. 295-308 14 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Deficiency of CRTH2, a prostaglandin D 2 receptor, aggravates bleomycin-induced pulmonary inflammation and fibrosis

Ueda, S., Fukunaga, K., Takihara, T., Shiraishi, Y., Oguma, T., Shiomi, T., Suzuki, Y., Ishii, M., Sayama, K., Kagawa, S., Hirai, H., Nagata, K., Nakamura, M., Miyasho, T., Betsuyaku, T. & Asano, K., 2019 Mar 1, In : American journal of respiratory cell and molecular biology. 60, 3, p. 289-298 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

First report of hepatobiliary Mycobacterium avium infection developing obstructive jaundice in a patient with neutralizing anti–interferon-gamma autoantibodies

Namkoong, H., Asakura, T., Ishii, M., Yoda, S., Masaki, K., Sakagami, T., Iwasaki, E., Yamagishi, Y., Kanai, T., Betsuyaku, T. & Hasegawa, N., 2019 Jan 1, In : New Microbes and New Infections. 27, p. 4-6 3 p.

Research output: Contribution to journalArticle

Low serum estradiol levels are related to Mycobacterium avium complex lung disease: A cross-sectional study

Uwamino, Y., Nishimura, T., Sato, Y., Tamizu, E., Asakura, T., Uno, S., Mori, M., Fujiwara, H., Ishii, M., Kawabe, H., Murata, M. & Hasegawa, N., 2019 Dec 16, In : BMC infectious diseases. 19, 1, 1055.

Research output: Contribution to journalArticle

Open Access

Obesity worsens the outcome of influenza virus infection associated with impaired type I interferon induction in mice

Namkoong, H., Ishii, M., Fujii, H., Asami, T., Yagi, K., Suzuki, S., Azekawa, S., Tasaka, S., Hasegawa, N. & Betsuyaku, T., 2019 May 28, In : Biochemical and Biophysical Research Communications. 513, 2, p. 405-411 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Prognostic values of the Berlin definition criteria, blood lactate level, and fibroproliferative changes on high-resolution computed tomography in ARDS patients

Kamo, T., Tasaka, S., Suzuki, T., Asakura, T., Suzuki, S., Yagi, K., Namkoong, H., Ishii, M., Morisaki, H. & Betsuyaku, T., 2019 Feb 11, In : BMC Pulmonary Medicine. 19, 1, 37.

Research output: Contribution to journalArticle

Open Access

Retrospective evaluation of natural course in mild cases of Mycobacterium avium complex pulmonary disease

for the Non-Tuberculous Mycobacteriosis-Japan Research Consortium (NTM-JRC), 2019 Apr 1, In : PloS one. 14, 4, e0216034.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Sitafloxacin-containing regimen for the treatment of refractory mycobacterium avium complex lung disease

Asakura, T., Suzuki, S., Fukano, H., Okamori, S., Kusumoto, T., Uwamino, Y., Ogawa, T., So, M., Uno, S., Namkoong, H., Yoshida, M., Kamata, H., Ishii, M., Nishimura, T., Hoshino, Y. & Hasegawa, N., 2019 Apr, In : Open Forum Infectious Diseases. 6, 4, ofz108.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
2018

Anti-inflammatory roles of mesenchymal stromal cells during acute Streptococcus pneumoniae pulmonary infection in mice

Asami, T., Ishii, M., Namkoong, H., Yagi, K., Tasaka, S., Asakura, T., Suzuki, S., Kamo, T., Okamori, S., Kamata, H., Zhang, H., Hegab, A. E., Hasegawa, N. & Betsuyaku, T., 2018 Mar 1, In : Cytotherapy. 20, 3, p. 302-313 12 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Aspergillus precipitating antibody in patients with Mycobacterium avium complex lung disease: A cross-sectional study

Suzuki, S., Asakura, T., Namkoong, H., Okamori, S., Yagi, K., Kamata, H., Uwamino, Y., Funatsu, Y., Nakano, Y., Nishimura, T., Ishii, M., Ebihara, T., Betsuyaku, T. & Hasegawa, N., 2018 May, In : Respiratory Medicine. 138, p. 1-6 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Association between six-minute walk test parameters and the health-related quality of life in patients with pulmonary Mycobacterium avium complex disease

Yagi, K., Asakura, T., Namkoong, H., Suzuki, S., Asami, T., Okamori, S., Kusumoto, T., Funatsu, Y., Kamata, H., Nishimura, T., Ishii, M., Betsuyaku, T. & Hasegawa, N., 2018 Jul 13, In : BMC Pulmonary Medicine. 18, 1, 114.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Bilateral upper lobe Pneumocystis pneumonia during aerosolized pentamidine prophylaxis

Ohara, Y., Asakura, T., Ueda, S., Yamada, Y., Ishii, M. & Betsuyaku, T., 2018 May 1, In : QJM. 111, 5, p. 337-338 2 p.

Research output: Contribution to journalArticle

Clarithromycin expands CD11b+Gr-1+cells via the STAT3/Bv8 axis to ameliorate lethal endotoxic shock and post-influenza bacterial pneumonia

Namkoong, H., Ishii, M., Fujii, H., Yagi, K., Asami, T., Asakura, T., Suzuki, S., Hegab, A. E., Kamata, H., Tasaka, S., Atarashi, K., Nakamoto, N., Iwata, S., Honda, K., Kanai, T., Hasegawa, N., Koyasu, S. & Betsuyaku, T., 2018 Apr 1, In : PLoS Pathogens. 14, 4, e1006955.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Clinical characteristics of pulmonary Mycobacterium lentiflavum disease in adult patients

Yagi, K., Morimoto, K., Ishii, M., Namkoong, H., Okamori, S., Asakura, T., Suzuki, S., Asami, T., Uwamino, Y., Funatsu, Y., Fujiwara, H., Kamata, H., Nishimura, T., Betsuyaku, T., Kurashima, A. & Hasegawa, N., 2018 Feb 1, In : International Journal of Infectious Diseases. 67, p. 65-69 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Development of lung cancer in patients with; nontuberculous mycobacterial lung disease

Kusumoto, T., Asakura, T., Suzuki, S., Okamori, S., Namkoong, H., Fujiwara, H., Yagi, K., Kamata, H., Ishii, M., Betsuyaku, T. & Hasegawa, N., 2018 Jan 1, (Accepted/In press) In : Respiratory Investigation.

Research output: Contribution to journalArticle

Efficacy and safety of intermittent maintenance therapy after successful treatment of Mycobacterium avium complex lung disease

Nontuberculous Mycobacteriosis Japan Research Consortium (NTM-JRC), 2018 Jan 1, (Accepted/In press) In : Journal of Infection and Chemotherapy.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Health-related QOL of elderly patients with pulmonary M. avium complex disease in a university hospital

Asakura, T., Ishii, M., Ishii, K., Suzuki, S., Namkoong, H., Okamori, S., Kamata, H., Yagi, K., Funatsu, Y., Betsuyaku, T. & Hasegawa, N., 2018 Jun 1, In : International Journal of Tuberculosis and Lung Disease. 22, 6, p. 695-703 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

High fat diet activates adult mouse lung stem cells and accelerates several aging-induced effects

Hegab, A. E., Ozaki, M., Meligy, F. Y., Kagawa, S., Ishii, M. & Betsuyaku, T., 2018 Dec 1, In : Stem Cell Research. 33, p. 25-35 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Natural history of Mycobacterium fortuitum pulmonary infection presenting with migratory infiltrates: A case report with microbiological analysis

Okamori, S., Asakura, T., Nishimura, T., Tamizu, E., Ishii, M., Yoshida, M., Fukano, H., Hayashi, Y., Fujita, M., Hoshino, Y., Betsuyaku, T. & Hasegawa, N., 2018 Jan 2, In : BMC Infectious Diseases. 18, 1, 1.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Pulmonary nocardiosis mimicking small cell lung cancer in ectopic ACTH syndrome associated with transformation of olfactory neuroblastoma: A case report

Kobayashi, K., Asakura, T., Ishii, M., Ueda, S., Irie, H., Ozawa, H., Saitoh, K., Kurihara, I., Itoh, H. & Betsuyaku, T., 2018 Aug 22, In : BMC Pulmonary Medicine. 18, 1, 142.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Quantitative assessment of erector spinae muscles in patients with Mycobacterium avium complex lung disease

Asakura, T., Yamada, Y., Suzuki, S., Namkoong, H., Okamori, S., Kusumoto, T., Niijima, Y., Ozaki, A., Hashimoto, M., Yagi, K., Kamata, H., Funatsu, Y., Ishii, M., Jinzaki, M., Betsuyaku, T. & Hasegawa, N., 2018 Dec 1, In : Respiratory Medicine. 145, p. 66-72 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Sphingosine 1-phosphate receptor modulator ONO-4641 stimulates CD11b+Gr-1+ cell expansion and inhibits lymphocyte infiltration in the lungs to ameliorate murine pulmonary emphysema

Asakura, T., Ishii, M., Namkoong, H., Suzuki, S., Kagawa, S., Yagi, K., Komiya, T., Hashimoto, T., Okamori, S., Kamata, H., Tasaka, S., Kihara, A., Hegab, A. E., Hasegawa, N. & Betsuyaku, T., 2018 Jan 1, (Accepted/In press) In : Mucosal Immunology.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2017
3 Citations (Scopus)

Effects of the common polymorphism in the human aldehyde dehydrogenase 2 (ALDH2) gene on the lung

Kuroda, A., Hegab, A. E., Jingtao, G., Yamashita, S., Hizawa, N., Sakamoto, T., Yamada, H., Suzuki, S., Ishii, M., Namkoong, H., Asakura, T., Ozaki, M., Yasuda, H., Hamamoto, J., Kagawa, S., Soejima, K. & Betsuyaku, T., 2017 Apr 21, In : Respiratory Research. 18, 1, 69.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Glycoprotein nanotube traps influenza virus

Yuge, S., Akiyama, M., Ishii, M., Namkoong, H., Yagi, K., Nakai, Y., Adachi, R. & Komatsu, T., 2017, In : Chemistry Letters. 46, 1, p. 95-97 3 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Impact of cavity and infiltration on pulmonary function and health-related quality of life in pulmonary Mycobacterium avium complex disease: A 3-dimensional computed tomographic analysis

Asakura, T., Yamada, Y., Namkoong, H., Suzuki, S., Niijima, Y., Kamata, H., Funatsu, Y., Yagi, K., Okamori, S., Sugiura, H., Ishii, M., Jinzaki, M., Betsuyaku, T. & Hasegawa, N., 2017 May 1, In : Respiratory Medicine. 126, p. 9-16 8 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Impact of chronic Pseudomonas aeruginosa infection on health-related quality of life in Mycobacterium avium complex lung disease

Kamata, H., Asakura, T., Suzuki, S., Namkoong, H., Yagi, K., Funatsu, Y., Okamori, S., Uno, S., Uwamino, Y., Fujiwara, H., Nishimura, T., Ishii, M., Betsuyaku, T. & Hasegawa, N., 2017 Dec 13, In : BMC Pulmonary Medicine. 17, 1, 198.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Long-term Outcome of Pulmonary Resection for Nontuberculous Mycobacterial Pulmonary Disease

Asakura, T., Hayakawa, N., Hasegawa, N., Namkoong, H., Takeuchi, K., Suzuki, S., Ishii, M., Betsuyaku, T., Abe, Y. & Ouchi, M., 2017 Jul 15, In : Clinical Infectious Diseases. 65, 2, p. 244-251 8 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Sternoclavicular joint osteomyelitis extending to lung abscess complicated by Staphylococcal infective endocarditis

Masuzawa, K., Asakura, T., Ishii, M., Yasuda, H., Sugiura, H. & Betsuyaku, T., 2017, In : IDCases. 9, p. 36-37 2 p.

Research output: Contribution to journalArticle

The efficacy, safety, and feasibility of inhaled amikacin for the treatment of difficult-to-treat non-tuberculous mycobacterial lung diseases

Yagi, K., Ishii, M., Namkoong, H., Asami, T., Iketani, O., Asakura, T., Suzuki, S., Sugiura, H., Yamada, Y., Nishimura, T., Fujiwara, H., Funatsu, Y., Uwamino, Y., Kamo, T., Tasaka, S., Betsuyaku, T. & Hasegawa, N., 2017 Aug 9, In : BMC Infectious Diseases. 17, 1, 558.

Research output: Contribution to journalArticle

23 Citations (Scopus)
2016

Blue-Black Trachea as a Result of Minocycline-induced Hyperpigmentation

Asakura, T., Nukaga, S., Namkoong, H., Yagi, K., Suzuki, S., Ishii, M., Tasaka, S., Betsuyaku, T. & Hasegawa, N., 2016 Feb 1, In : American Journal of Respiratory and Critical Care Medicine. 193, 3, p. e5-e6

Research output: Contribution to journalArticle

3 Citations (Scopus)

Clinical characteristics of pulmonary Mycobacterium scrofulaceum disease in 2001–2011: A case series and literature review

Suzuki, S., Morino, E., Ishii, M., Namkoong, H., Yagi, K., Asakura, T., Asami, T., Fujiwara, H., Uwamino, Y., Nishimura, T., Tasaka, S., Betsuyaku, T., Takasaki, J., Iwata, S. & Hasegawa, N., 2016 Sep 1, In : Journal of Infection and Chemotherapy. 22, 9, p. 611-616 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Clinical efficacy and safety of multidrug therapy including thrice weekly intravenous amikacin administration for Mycobacterium abscessus pulmonary disease in outpatient settings: A case series

Namkoong, H., Morimoto, K., Nishimura, T., Tanaka, H., Sugiura, H., Yamada, Y., Kurosaki, A., Asakura, T., Suzuki, S., Fujiwara, H., Yagi, K., Ishii, M., Tasaka, S., Betsuyaku, T., Hoshino, Y., Kurashima, A. & Hasegawa, N., 2016 Aug 9, In : BMC Infectious Diseases. 16, 1, 396.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Disseminated mycobacterium marinum infection with a destructive nasal lesion mimicking extranodal NK/T cell lymphoma: A case report

Asakura, T., Ishii, M., Kikuchi, T., Kameyama, K., Namkoong, H., Nakata, N., Sugita, K., Tasaka, S., Shimizu, T., Hoshino, Y., Okamoto, S., Betsuyaku, T. & Hasegawa, N., 2016, In : Medicine (United States). 95, 11, e3131.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Histone Deacetylase Inhibition Protects Mice Against Lethal Postinfluenza Pneumococcal Infection

Yagi, K., Ishii, M., Namkoong, H., Fujii, H., Asami, T., Suzuki, S., Asakura, T., Mizoguchi, K., Kamo, T., Tasaka, S., Iwata, S., Kunkel, S. L., Hasegawa, N. & Betsuyaku, T., 2016 Oct 1, In : Critical care medicine. 44, 10, p. e980-e987

Research output: Contribution to journalArticle

9 Citations (Scopus)

Inflammation in infection and immunity

Ishii, M., 2016 Feb 1, In : Respiration and Circulation. 64, 2, p. 119-124 6 p.

Research output: Contribution to journalArticle

Levels of soluble receptor for advanced glycation end products in bronchoalveolar lavage fluid in patients with various inflammatory lung diseases

Kamo, T., Tasaka, S., Tokuda, Y., Suzuki, S., Asakura, T., Yagi, K., Namkoong, H., Ishii, M., Hasegawa, N. & Betsuyaku, T., 2016 Apr 28, In : Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine. 9, p. 147-154 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Macrolide-resistant mycobacterium avium complex lung disease: Analysis of 102 consecutive cases

Nontuberculous Mycobacteriosis Japan Research Consortium, 2016 Nov 1, In : Annals of the American Thoracic Society. 13, 11, p. 1904-1911 8 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Pharmacokinetics of intravenous peramivir in the airway epithelial lining fluid of healthy volunteers

Funatsu, Y., Tasaka, S., Asami, T., Namkoong, H., Fujiwara, H., Iketani, O., Yagi, K., Kimizuka, Y., Ishii, M., Nishimura, T., Ogata, H., Iwata, S., Betsuyaku, T. & Hasegawa, N., 2016, In : Antiviral Therapy. 21, 7, p. 621-625 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Pneumococcal Infection Aggravates Elastase-Induced Emphysema via Matrix Metalloproteinase 12 Overexpression

Takahashi, S., Ishii, M., Namkoong, H., Hegab, A. E., Asami, T., Yagi, K., Sasaki, M., Haraguchi, M., Sato, M., Kameyama, N., Asakura, T., Suzuki, S., Tasaka, S., Iwata, S., Hasegawa, N. & Betsuyaku, T., 2016 Mar 15, In : Journal of Infectious Diseases. 213, 6, p. 1018-1030 13 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Pneumothorax associated with nontuberculous mycobacteria A retrospective study of 69 patients

Ueyama, M., Asakura, T., Morimoto, K., Namkoong, H., Matsuda, S., Osawa, T., Ishii, M., Hasegawa, N., Kurashima, A. & Goto, H., 2016 Jul 26, In : Medicine (United States). 95, 29, e4246.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Theory and strategy for Pneumococcal vaccines in the elderly

Namkoong, H., Ishii, M., Funatsu, Y., Kimizuka, Y., Yagi, K., Asami, T., Asakura, T., Suzuki, S., Kamo, T., Fujiwara, H., Tasaka, S., Betsuyaku, T. & Hasegawa, N., 2016 Feb 1, In : Human Vaccines and Immunotherapeutics. 12, 2, p. 336-343 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2015

Comparison of the immunogenicity and safety of polysaccharide and protein-conjugated pneumococcal vaccines among the elderly aged 80 years or older in Japan: An open-labeled randomized study

Namkoong, H., Funatsu, Y., Oishi, K., Akeda, Y., Hiraoka, R., Takeshita, K., Asami, T., Yagi, K., Kimizuka, Y., Ishii, M., Tasaka, S., Suzuki, Y., Iwata, S., Betsuyaku, T. & Hasegawa, N., 2015 Jan 3, In : Vaccine. 33, 2, p. 327-332 6 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Dry pleurisy complicating solitary pulmonary nodules caused by Mycobacterium avium: A case report

Asakura, T., Ishii, M., Haraguchi, M., Kamiyama, I., Kohno, M., Sakamaki, H., Emoto, K., Hayashi, Y., Sugiura, H., Kawada, I., Soejima, K., Namkoong, H., Tasaka, S., Hasegawa, N. & Betsuyaku, T., 2015 Oct 26, (Accepted/In press) In : Journal of Medical Case Reports.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Fatal fulminant pneumonia caused by methicillin-sensitive staphylococcus aureus negative for major high-virulence factors following influenza B virus infection

Masaki, K., Ishii, M., Anraku, M., Namkoong, H., Miyakawa, R., Nakajima, T., Fukunaga, K., Naoki, K., Tasaka, S., Soejima, K., Sayama, K., Sugita, K., Iwata, S., Cui, L., Hanaki, H., Hasegawa, N. & Betsuyaku, T., 2015 Jul 14, In : American Journal of Case Reports. 16, p. 454-458 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Fournier’s gangrene: a surgical emergency

Namkoong, H., Ishii, M., Koizumi, M. & Betsuyaku, T., 2015 Jul 3, (Accepted/In press) In : Infection.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Health-related quality of life is inversely correlated with C-reactive protein and age in Mycobacterium avium complex lung disease: A cross-sectional analysis of 235 patients

Asakura, T., Funatsu, Y., Ishii, M., Namkoong, H., Yagi, K., Suzuki, S., Asami, T., Kamo, T., Fujiwara, H., Uwamino, Y., Nishimura, T., Tasaka, S., Betsuyaku, T. & Hasegawa, N., 2015 Dec 3, (Accepted/In press) In : Respiratory Research.

Research output: Contribution to journalArticle

18 Citations (Scopus)