• 19063 Citations
  • 71 h-Index
1988 …2020

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Article
2020

Diagnosis and management of pemphigus: Recommendations of an international panel of experts

Murrell, D. F., Peña, S., Joly, P., Marinovic, B., Hashimoto, T., Diaz, L. A., Sinha, A. A., Payne, A. S., Daneshpazhooh, M., Eming, R., Jonkman, M. F., Mimouni, D., Borradori, L., Kim, S. C., Yamagami, J., Lehman, J. S., Saleh, M. A., Culton, D. A., Czernik, A., Zone, J. J. & 38 others, Fivenson, D., Ujiie, H., Wozniak, K., Akman-Karakaş, A., Bernard, P., Korman, N. J., Caux, F., Drenovska, K., Prost-Squarcioni, C., Vassileva, S., Feldman, R. J., Cardones, A. R., Bauer, J., Ioannides, D., Jedlickova, H., Palisson, F., Patsatsi, A., Uzun, S., Yayli, S., Zillikens, D., Amagai, M., Hertl, M., Schmidt, E., Aoki, V., Grando, S. A., Shimizu, H., Baum, S., Cianchini, G., Feliciani, C., Iranzo, P., Mascaró, J. M., Kowalewski, C., Hall, R., Groves, R., Harman, K. E., Marinkovich, M. P., Maverakis, E. & Werth, V. P., 2020 Mar, In : Journal of the American Academy of Dermatology. 82, 3, p. 575-585.e1

Research output: Contribution to journalArticle

40 Citations (Scopus)

HaloTag-based conjugation of proteins to barcoding-oligonucleotides

Yazaki, J., Kawashima, Y., Ogawa, T., Kobayashi, A., Okoshi, M., Watanabe, T., Yoshida, S., Kii, I., Egami, S., Amagai, M., Hosoya, T., Shiroguchi, K. & Ohara, O., 2020 Jan 24, In : Nucleic acids research. 48, 2, e8.

Research output: Contribution to journalArticle

Open Access

Holocrine Secretion Occurs outside the Tight Junction Barrier in Multicellular Glands: Lessons from Claudin-1–Deficient Mice

Atsugi, T., Yokouchi, M., Hirano, T., Hirabayashi, A., Nagai, T., Ohyama, M., Abe, T., Kaneko, M., Zouboulis, C. C., Amagai, M. & Kubo, A., 2020 Feb, In : Journal of Investigative Dermatology. 140, 2, p. 298-308.e5

Research output: Contribution to journalArticle

Open Access
Open Access

Pemphigus Vulgaris and Foliaceus IgG Autoantibodies Directly Block Heterophilic Transinteraction between Desmoglein and Desmocollin

Ishii, K., Yoshida, K., Stanley, J. R., Yamagami, J., Amagai, M. & Ishiko, A., 2020 Jan 1, (Accepted/In press) In : Journal of Investigative Dermatology.

Research output: Contribution to journalArticle

Results of the guideline-based treatment for pemphigus: a single-centre experience with 84 cases

Kakuta, R., Kurihara, Y., Yamagami, J., Miyamoto, J., Funakoshi, T., Tanikawa, A. & Amagai, M., 2020 Jun 1, In : Journal of the European Academy of Dermatology and Venereology. 34, 6, p. 1324-1330 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Strategic outlook toward 2030: Japan's research for allergy and immunology

Adachi, T., Kainuma, K., Asano, K., Amagai, M., Arai, H., Ishii, K. J., Ito, K., Uchio, E., Ebisawa, M., Okano, M., Kabashima, K., Kondo, K., Konno, S., Saeki, H., Sonobe, M., Nagao, M., Hizawa, N., Fukushima, A., Fujieda, S., Matsumoto, K. & 4 others, Morita, H., Yamamoto, K., Yoshimoto, A. & Tamari, M., 2020 Jan 1, In : Japanese Journal of Allergology. 69, 1, p. 23-33 11 p.

Research output: Contribution to journalArticle

Targeting inducible costimulator expressed on CXCR5+PD-1+ TH cells suppresses the progression of pemphigus vulgaris

Kim, A. R., Han, D., Choi, J. Y., Seok, J., Kim, S. E., Seo, S. H., Takahashi, H., Amagai, M., Park, S. H., Kim, S. C., Shin, E. C. & Kim, J. H., 2020 Jan 1, (Accepted/In press) In : Journal of Allergy and Clinical Immunology.

Research output: Contribution to journalArticle

Open Access
2019

Abl family tyrosine kinases govern IgG extravasation in the skin in a murine pemphigus model

Ono, S., Egawa, G., Nomura, T., Kitoh, A., Dainichi, T., Otsuka, A., Nakajima, S., Amagai, M., Matsumoto, F., Yamamoto, M., Kubota, Y., Takai, T., Honda, T. & Kabashima, K., 2019 Dec 1, In : Nature communications. 10, 1, 4432.

Research output: Contribution to journalArticle

Open Access

Basement membrane zone IgE deposition is associated with bullous pemphigoid disease severity and treatment results

Kamata, A., Kurihara, Y., Funakoshi, T., Takahashi, H., Kuroda, K., Hachiya, T., Amagai, M. & Yamagami, J., 2019 Jan 1, (Accepted/In press) In : British Journal of Dermatology.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Cell-autonomous FLT3L shedding via ADAM10 mediates conventional dendritic cell development in mouse spleen

Fujita, K., Chakarov, S., Kobayashi, T., Sakamoto, K., Voisin, B., Duan, K., Nakagawa, T., Horiuchi, K., Amagai, M., Ginhoux, F. & Nagao, K., 2019 Jan 1, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 29, p. 14714-14723 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Clonal Expansion of Second-Hit Cells with Somatic Recombinations or C>T Transitions Form Porokeratosis in MVD or MVK Mutant Heterozygotes

Kubo, A., Sasaki, T., Suzuki, H., Shiohama, A., Aoki, S., Sato, S., Fujita, H., Ono, N., Umegaki-Arao, N., Kawai, T., Nakabayashi, K., Hata, K., Yamada, D., Matsubara, Y., Kosaki, K. & Amagai, M., 2019 Dec, In : Journal of Investigative Dermatology. 139, 12, p. 2458-2466.e9

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Co-activation of macrophages and T cells contribute to chronic GVHD in human IL-6 transgenic humanised mouse model

Ono, R., Watanabe, T., Kawakami, E., Iwasaki, M., Tomizawa-Murasawa, M., Matsuda, M., Najima, Y., Takagi, S., Fujiki, S., Sato, R., Mochizuki, Y., Yoshida, H., Sato, K., Yabe, H., Kato, S., Saito, Y., Taniguchi, S., Shultz, L. D., Ohara, O., Amagai, M. & 2 others, Koseki, H. & Ishikawa, F., 2019 Mar, In : EBioMedicine. 41, p. 584-596 13 p.

Research output: Contribution to journalArticle

Open Access

Development of an electronic medical record-based algorithm to identify patients with Stevens-Johnson syndrome and toxic epidermal necrolysis in Japan

Fukasawa, T., Takahashi, H., Kameyama, N., Fukuda, R., Furuhata, S., Tanemura, N., Amagai, M. & Urushihara, H., 2019 Jan 1, In : PloS one. 14, 8, e0221130.

Research output: Contribution to journalArticle

Open Access

Filaggrin Expression and Processing Deficiencies Impair Corneocyte Surface Texture and Stiffness in Mice

Thyssen, J. P., Jakasa, I., Riethmüller, C., Schön, M. P., Braun, A., Haftek, M., Fallon, P. G., Wróblewski, J., Jakubowski, H., Eckhart, L., Declercq, W., Koppes, S., Engebretsen, K. A., Bonefeld, C., Irvine, A. D., Keita-Alassane, S., Simon, M., Kawasaki, H., Kubo, A., Amagai, M. & 2 others, Matsui, T. & Kezic, S., 2019 Jan 1, (Accepted/In press) In : Journal of Investigative Dermatology.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Homeostatic pruning and activity of epidermal nerves are dysregulated in barrier-impaired skin during chronic itch development

Takahashi, S., Ishida, A., Kubo, A., Kawasaki, H., Ochiai, S., Nakayama, M., Koseki, H., Amagai, M. & Okada, T., 2019 Dec 1, In : Scientific reports. 9, 1, 8625.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Japanese guidelines for the management of pemphigoid (including epidermolysis bullosa acquisita)

Committee for Guidelines for the Management of Pemphigoid Diseases (Including Epidermolysis Bullosa Acquisita), 2019 Jan 1, (Accepted/In press) In : Journal of Dermatology.

Research output: Contribution to journalArticle

3 Citations (Scopus)
Open Access
2 Citations (Scopus)

Results of a nationwide epidemiologic survey of autosomal recessive congenital ichthyosis and ichthyosis syndromes in Japan

Kurosawa, M., Uehara, R., Takagi, A., Aoyama, Y., Iwatsuki, K., Amagai, M., Nagai, M., Nakamura, Y., Inaba, Y., Yokoyama, K. & Ikeda, S., 2019 Nov, In : Journal of the American Academy of Dermatology. 81, 5, p. 1086-1092.e1

Research output: Contribution to journalArticle

Rituximab therapy for refractory autoimmune bullous diseases: A multicenter, open-label, single-arm, phase 1/2 study on 10 Japanese patients

Kurihara, Y., Yamagami, J., Funakoshi, T., Ishii, M., Miyamoto, J., Fujio, Y., Kakuta, R., Tanikawa, A., Aoyama, Y., Iwatsuki, K., Ishii, N., Hashimoto, T., Nishie, W., Shimizu, H., Kouyama, K. & Amagai, M., 2019 Feb 1, In : Journal of Dermatology. 46, 2, p. 124-130 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2 Citations (Scopus)

The desmosome is a mesoscale lipid raft-like membrane domain

Lewis, J. D., Caldara, A. L., Zimmer, S. E., Stahley, S. N., Seybold, A., Strong, N. L., Frangakis, A. S., Levental, I., Wahl, J. K., Mattheyses, A. L., Sasaki, T., Nakabayashi, K., Hata, K., Matsubara, Y., Ishida-Yamamoto, A., Amagai, M., Kubo, A. & Kowalczyk, A. P., 2019 Jun 1, In : Molecular biology of the cell. 30, 12, p. 1390-1405 16 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Toward a new generation of smart skins

Someya, T. & Amagai, M., 2019 Apr 1, In : Nature Biotechnology. 37, 4, p. 382-388 7 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)
2018

Assessment of the methods used to detect HER2-positive advanced extramammary Paget’s disease

Hirai, I., Tanese, K., Nakamura, Y., Otsuka, A., Fujisawa, Y., Yamamoto, Y., Hata, H., Fujimura, T., Matsushita, S., Yoshino, K., Kameyama, K., Amagai, M. & Funakoshi, T., 2018 Jun 1, In : Medical Oncology. 35, 6, 92.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Bone Marrow-Derived Stem Cells Migrate into Intraepidermal Skin Defects of a Desmoglein-3 Knockout Mouse Model but Preserve their Mesodermal Differentiation

Hünefeld, C., Mezger, M., Müller-Hermelink, E., Schaller, M., Müller, I., Amagai, M., Handgretinger, R. & Röcken, M., 2018 May 1, In : Journal of Investigative Dermatology. 138, 5, p. 1157-1165 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Case of lamotrigine-induced drug adverse reaction under tocilizumab treatment with clinical and virological features of drug-induced hypersensitivity syndrome

Iriki, H., Ouchi, T., Ito, H., Sawada, M., Mukai, M., Nomura, H., Baba, Y., Adachi, T., Funakoshi, T., Amagai, M. & Takahashi, H., 2018 Jan 1, (Accepted/In press) In : Journal of Dermatology.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Characterization of centriole duplication in human epidermis, Bowen's disease, and squamous cell carcinoma

Watanuki, S., Fujita, H., Koyama, K., Amagai, M. & Kubo, A., 2018 Jan 1, (Accepted/In press) In : Journal of Dermatological Science.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Identification of a human papillomavirus type 58 lineage in multiple Bowen's disease on the fingers: Case report and published work review

Kobayashi, K., Tanese, K., Kubo, A., Matsumoto-Mochimaru, N., Sasaki, A., Kameyama, K., Amagai, M. & Umegaki, N., 2018 Jan 1, (Accepted/In press) In : Journal of Dermatology.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Langerhans Cells Prevent Autoimmunity via Expansion of Keratinocyte Antigen-Specific Regulatory T Cells

Kitashima, D. Y., Kobayashi, T., Woodring, T., Idouchi, K., Doebel, T., Voisin, B., Adachi, T., Ouchi, T., Takahashi, H., Nishifuji, K., Kaplan, D. H., Clausen, B. E., Amagai, M. & Nagao, K., 2018 Jan 1, (Accepted/In press) In : EBioMedicine.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Unique clinical and serological features of bullous pemphigoid associated with dipeptidyl peptidase-4 inhibitors

Horikawa, H., Kurihara, Y., Funakoshi, T., Umegaki, N., Takahashi, H., Kubo, A., Tanikawa, A., Kodani, N., Minami, Y., Meguro, S., Itoh, H., Izumi, K., Nishie, W., Shimizu, H., Amagai, M. & Yamagami, J., 2018 Jan 1, (Accepted/In press) In : British Journal of Dermatology.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Vancomycin Mediates IgA Autoreactivity in Drug-Induced Linear IgA Bullous Dermatosis

Yamagami, J., Nakamura, Y., Nagao, K., Funakoshi, T., Takahashi, H., Tanikawa, A., Hachiya, T., Yamamoto, T., Ishida-Yamamoto, A., Tanaka, T., Fujimoto, N., Nishigori, C., Yoshida, T., Ishii, N., Hashimoto, T. & Amagai, M., 2018 Jul, In : Journal of Investigative Dermatology. 138, 7, p. 1473-1480 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

自己免疫性水疱症の上部消化管内視鏡所見

Translated title of the contribution: Endoscopic findings of laryngopharyngeal and esophageal involvement in autoimmune bullous diseaseNakamura, R., Omori, T., Suda, K., Wada, N., Kawakubo, H., Takeuchi, H., Yamagami, J., Amagai, M. & Kitagawa, Y., 2018 Aug 1, In : Gastroenterological Endoscopy. 60, 8, p. 1515-1526 12 p.

Research output: Contribution to journalArticle

2017

A randomized double-blind trial of intravenous immunoglobulin for bullous pemphigoid

Bullous Pemphigoid Study Group, 2017 Feb 1, In : Journal of Dermatological Science. 85, 2, p. 77-84 8 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Association study of childhood food allergy with genome-wide association studies-discovered loci of atopic dermatitis and eosinophilic esophagitis

Hirota, T., Nakayama, T., Sato, S., Yanagida, N., Matsui, T., Sugiura, S., Takaoka, Y., Hizawa, N., Fujieda, S., Miyatake, A., Sasaki, T., Amagai, M., Doi, S., Ito, K., Sasaki, T. & Amagai, M., 2017, (Accepted/In press) In : Journal of Allergy and Clinical Immunology.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Azathioprine monotherapy in autoimmune blistering diseases: A feasible option for mild to moderate cases

Kakuta, R., Yamagami, J., Funakoshi, T., Takahashi, H., Ohyama, M. & Amagai, M., 2017 Jan 1, (Accepted/In press) In : Journal of Dermatology.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Dermoscopy of pigmented invasive ductal carcinoma mimicking basal cell carcinoma

Horikawa, H., Umegaki, N., Funakoshi, T., Amagai, M. & Tanaka, M., 2017, (Accepted/In press) In : Australasian Journal of Dermatology.

Research output: Contribution to journalArticle

1 Citation (Scopus)

E-cadherin integrates mechanotransduction and EGFR signaling to control junctional tissue polarization and tight junction positioning

Rübsam, M., Mertz, A. F., Kubo, A., Marg, S., Jüngst, C., Goranci-Buzhala, G., Schauss, A. C., Horsley, V., Dufresne, E. R., Moser, M., Ziegler, W., Amagai, M., Wickström, S. A. & Niessen, C. M., 2017 Dec 1, In : Nature Communications. 8, 1, 1250.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Endoscopic findings of laryngopharyngeal and esophageal involvement in autoimmune bullous disease

Nakamura, R., Omori, T., Suda, K., Wada, N., Kawakubo, H., Takeuchi, H., Yamagami, J., Amagai, M. & Kitagawa, Y., 2017, (Accepted/In press) In : Digestive Endoscopy.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2 Citations (Scopus)

Induction of hair follicle dermal papilla cell properties in human induced pluripotent stem cell-derived multipotent LNGFR(+)THY-1(+) mesenchymal cells

Veraitch, O., Mabuchi, Y., Matsuzaki, Y., Sasaki, T., Okuno, H., Tsukashima, A., Amagai, M., Okano, H. & Ohyama, M., 2017 Feb 21, In : Scientific Reports. 7, 42777.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Inflammation-free, gas-permeable, lightweight, stretchable on-skin electronics with nanomeshes

Miyamoto, A., Lee, S., Cooray, N. F., Lee, S., Mori, M., Matsuhisa, N., Jin, H., Yoda, L., Yokota, T., Itoh, A., Sekino, M., Kawasaki, H., Ebihara, T., Amagai, M. & Someya, T., 2017 Sep 1, In : Nature Nanotechnology. 12, 9, p. 907-913 7 p.

Research output: Contribution to journalArticle

236 Citations (Scopus)

Inflammatory Linear Verrucous Epidermal Nevus with a Postzygotic GJA1 Mutation Is a Mosaic Erythrokeratodermia Variabilis et Progressiva

Umegaki, N., Sasaki, T., Fujita, H., Aoki, S., Kameyama, K., Amagai, M., Seishima, M. & Kubo, A., 2017 Apr 1, In : Journal of Investigative Dermatology. 137, 4, p. 967-970 4 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Intestinal Dysbiosis and Biotin Deprivation Induce Alopecia through Overgrowth of Lactobacillus murinus in Mice

Hayashi, A., Mikami, Y., Miyamoto, K., Kamada, N., Sato, T., Mizuno, S., Naganuma, M., Teratani, T., Aoki, R., Fukuda, S., Suda, W., Hattori, M., Amagai, M., Ohyama, M. & Kanai, T., 2017 Aug 15, In : Cell Reports. 20, 7, p. 1513-1524 12 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Lack of XAGE-1b and NY-ESO-1 in metastatic lymph nodes may predict the potential survival of stage III melanoma patients

Mori, M., Funakoshi, T., Kameyama, K., Kawakami, Y., Sato, E., Nakayama, E., Amagai, M. & Tanese, K., 2017, (Accepted/In press) In : Journal of Dermatology.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Meeting Report of the Pathogenesis of Pemphigus and Pemphigoid Meeting in Munich, September 2016

Schmidt, E., Spindler, V., Eming, R., Amagai, M., Antonicelli, F., Baines, J. F., Belheouane, M., Bernard, P., Borradori, L., Caproni, M., Di Zenzo, G., Grando, S., Harman, K., Jonkman, M. F., Koga, H., Ludwig, R. J., Kowalczyk, A. P., Müller, E. J., Nishie, W., Pas, H. & 12 others, Payne, A. S., Sadik, C. D., Seppänen, A., Setterfield, J., Shimizu, H., Sinha, A. A., Sprecher, E., Sticherling, M., Ujiie, H., Zillikens, D., Hertl, M. & Waschke, J., 2017 Jun 1, In : Journal of Investigative Dermatology. 137, 6, p. 1199-1203 5 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Non-pathogenic pemphigus foliaceus (PF) IgG acts synergistically with a directly pathogenic PF IgG to increase blistering by p38MAPK-dependent desmoglein 1 clustering

Yoshida, K., Ishii, K., Shimizu, A., Yokouchi, M., Amagai, M., Shiraishi, K., Shirakata, Y., Stanley, J. R. & Ishiko, A., 2017 Mar 1, In : Journal of Dermatological Science. 85, 3, p. 197-207 11 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)