• 10100 Citations
  • 43 h-Index
1984 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

2020

Visualization of AMPA receptors in living human brain with positron emission tomography

Miyazaki, T., Nakajima, W., Hatano, M., Shibata, Y., Kuroki, Y., Arisawa, T., Serizawa, A., Sano, A., Kogami, S., Yamanoue, T., Kimura, K., Hirata, Y., Takada, Y., Ishiwata, Y., Sonoda, M., Tokunaga, M., Seki, C., Nagai, Y., Minamimoto, T., Kawamura, K. & 17 others, Zhang, M. R., Ikegaya, N., Iwasaki, M., Kunii, N., Kimura, Y., Yamashita, F., Taguri, M., Tani, H., Nagai, N., Koizumi, T., Nakajima, S., Mimura, M., Yuzaki, M., Kato, H., Higuchi, M., Uchida, H. & Takahashi, T., 2020 Feb 1, In : Nature medicine. 26, 2, p. 281-288 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2019

Activity-Dependent Secretion of Synaptic Organizer Cbln1 from Lysosomes in Granule Cell Axons

Ibata, K., Kono, M., Narumi, S., Motohashi, J., Kakegawa, W., Kohda, K. & Yuzaki, M., 2019 Jun 19, In : Neuron. 102, 6, p. 1184-1198.e10

Research output: Contribution to journalArticle

1 Citation (Scopus)

Hyaluronan synthesis supports glutamate transporter activity

Hayashi, M. K., Nishioka, T., Shimizu, H., Takahashi, K., Kakegawa, W., Mikami, T., Hirayama, Y., Koizumi, S., Yoshida, S., Yuzaki, M., Tammi, M., Sekino, Y., Kaibuchi, K., Shigemoto-Mogami, Y., Yasui, M. & Sato, K., 2019 Jan 1, In : Journal of Neurochemistry.

Research output: Contribution to journalArticle

Interneuronal NMDA receptors regulate long-term depression and motor learning in the cerebellum

Kono, M., Kakegawa, W., Yoshida, K. & Yuzaki, M., 2019 Feb 1, In : Journal of Physiology. 597, 3, p. 903-920 18 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

In vivoTwo-photon imaging of anesthesia-specific alterations in microglial surveillance and photodamage-directed motility in mouse cortex

Sun, W., Suzuki, K., Toptunov, D., Stoyanov, S., Yuzaki, M., Khiroug, L. & Dityatev, A., 2019 Jan 1, In : Frontiers in Neuroscience. 13, MAY, 421.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Mice lacking EFA6C/Psd2, a guanine nucleotide exchange factor for Arf6, exhibit lower Purkinje cell synaptic density but normal cerebellar motor functions

Saegusa, S., Fukaya, M., Kakegawa, W., Tanaka, M., Katsumata, O., Sugawara, T., Hara, Y., Itakura, M., Okubo, T., Sato, T., Yuzaki, M. & Sakagami, H., 2019 May 1, In : PloS one. 14, 5, e0216960.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

PhotonSABER: new tool shedding light on endocytosis and learning mechanisms in vivo

Matsuda, S., Kakegawa, W. & Yuzaki, M., 2019 Jan 1, In : Communicative and Integrative Biology. 12, 1, p. 34-37 4 p.

Research output: Contribution to journalArticle

Open Access

PIP 3 -Phldb2 is crucial for LTP regulating synaptic NMDA and AMPA receptor density and PSD95 turnover

Xie, M. J., Ishikawa, Y., Yagi, H., Iguchi, T., Oka, Y., Kuroda, K., Iwata, K., Kiyonari, H., Matsuda, S., Matsuzaki, H., Yuzaki, M., Fukazawa, Y. & Sato, M., 2019 Dec 1, In : Scientific reports. 9, 1, 4305.

Research output: Contribution to journalArticle

Open Access
2018

Caveolin-1 Promotes Early Neuronal Maturation via Caveolae-Independent Trafficking of N-Cadherin and L1

Shikanai, M., Nishimura, Y. V., Sakurai, M., Nabeshima, Y. I., Yuzaki, M. & Kawauchi, T., 2018 Sep 28, In : iScience. 7, p. 53-67 15 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Cellular and Subcellular Localization of Endogenous Neuroligin-1 in the Cerebellum

Nozawa, K., Hayashi, A., Motohashi, J., Takeo, Y. H., Matsuda, K. & Yuzaki, M., 2018 Jan 1, (Accepted/In press) In : Cerebellum.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Functional interactions between transient receptor potential M8 and transient receptor potential V1 in the trigeminal system: Relevance to migraine pathophysiology

Kayama, Y., Shibata, M., Takizawa, T., Ibata, K., Shimizu, T., Ebine, T., Toriumi, H., Yuzaki, M. & Suzuki, N., 2018 Apr 1, In : Cephalalgia. 38, 5, p. 833-845 13 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Improvement of cerebellar ataxic gait by injecting Cbln1 into the cerebellum of cbln1-null mice

Takeuchi, E., Ishida, A., Yuzaki, M. & Yanagihara, D., 2018 Dec 1, In : Scientific Reports. 8, 1, 6184.

Research output: Contribution to journalArticle

3 Citations (Scopus)

La Dolce Vita of Neurexin: Synaptic Partnerships through Glycosaminoglycans

Suzuki, K. & Yuzaki, M., 2018 Sep 6, In : Cell. 174, 6, p. 1337-1338 2 p.

Research output: Contribution to journalShort survey

Molecular Mechanisms for Learning and Memory: What Happens at the Synapses?

Kakegawa, W. & Yuzaki, M., 2018 Jul 1, In : Brain and nerve = Shinkei kenkyu no shinpo. 70, 7, p. 677-687 11 p.

Research output: Contribution to journalArticle

Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice

Ogiwara, I., Miyamoto, H., Tatsukawa, T., Yamagata, T., Nakayama, T., Atapour, N., Miura, E., Mazaki, E., Ernst, S. J., Cao, D., Ohtani, H., Itohara, S., Yanagawa, Y., Montal, M., Yuzaki, M., Inoue, Y., Hensch, T. K., Noebels, J. L. & Yamakawa, K., 2018 Dec 1, In : Communications Biology. 1, 1, 96.

Research output: Contribution to journalArticle

Open Access
14 Citations (Scopus)

Optogenetic Control of Synaptic AMPA Receptor Endocytosis Reveals Roles of LTD in Motor Learning

Kakegawa, W., Katoh, A., Narumi, S., Miura, E., Motohashi, J., Takahashi, A., Kohda, K., Fukazawa, Y., Yuzaki, M. & Matsuda, S., 2018 Sep 5, In : Neuron. 99, 5, p. 985-998.e6

Research output: Contribution to journalArticle

18 Citations (Scopus)

Rab family small GTPases-mediated regulation of intracellular logistics in neural development

Shikanai, M., Yuzaki, M. & Kawauchi, T., 2018 Aug 1, In : Histology and Histopathology. 33, 8, p. 765-771 7 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)

Spatiotemporal regulation of the GPCR activity of BAI3 by C1qL4 and Stabilin-2 controls myoblast fusion

Hamoud, N., Tran, V., Aimi, T., Kakegawa, W., Lahaie, S., Thibault, M. P., Pelletier, A., Wong, G. W., Kim, I. S., Kania, A., Yuzaki, M., Bouvier, M. & Côté, J. F., 2018 Dec 1, In : Nature Communications. 9, 1, 4470.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Two Classes of Secreted Synaptic Organizers in the Central Nervous System

Yuzaki, M., 2018 Feb 10, In : Annual Review of Physiology. 80, p. 243-262 20 p.

Research output: Contribution to journalReview article

15 Citations (Scopus)
2017

Chemical labelling for visualizing native AMPA receptors in live neurons

Wakayama, S., Kiyonaka, S., Arai, I., Kakegawa, W., Matsuda, S., Ibata, K., Nemoto, Y. L., Kusumi, A., Yuzaki, M. & Hamachi, I., 2017 Apr 7, In : Nature Communications. 8, 14850.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Dendritic Homeostasis Disruption in a Novel Frontotemporal Dementia Mouse Model Expressing Cytoplasmic Fused in Sarcoma

Shiihashi, G., Ito, D., Arai, I., Kobayashi, Y., Hayashi, K., Otsuka, S., Nakajima, K., Yuzaki, M., Itohara, S. & Suzuki, N., 2017 Oct, In : EBioMedicine. 24, p. 102-115 14 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Glutamate transporter GLAST controls synaptic wrapping by Bergmann glia and ensures proper wiring of Purkinje cells

Miyazaki, T., Yamasaki, M., Hashimoto, K., Kohda, K., Yuzaki, M., Shimamoto, K., Tanaka, K., Kano, M. & Watanabe, M., 2017 Jul 11, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 28, p. 7438-7443 6 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

MTCL1 plays an essential role in maintaining Purkinje neuron axon initial segment

Satake, T., Yamashita, K., Hayashi, K., Miyatake, S., Tamura-Nakano, M., Doi, H., Furuta, Y., Shioi, G., Miura, E., Takeo, Y. H., Yoshida, K., Yahikozawa, H., Matsumoto, N., Yuzaki, M. & Suzuki, A., 2017 May 2, In : EMBO Journal. 36, 9, p. 1227-1242 16 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Neural differentiation of human embryonic stem cells induced by the transgene-mediated overexpression of single transcription factors

Matsushita, M., Nakatake, Y., Arai, I., Ibata, K., Kohda, K., Goparaju, S. K., Murakami, M., Sakota, M., Chikazawa-Nohtomi, N., Ko, S., Kanai, T., Yuzaki, M. & Ko, M., 2017 May 31, (Accepted/In press) In : Biochemical and Biophysical Research Communications.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Rapid differentiation of human pluripotent stem cells into functional neurons by mRNAs encoding transcription factors

Goparaju, S. K., Kohda, K., Ibata, K., Soma, A., Nakatake, Y., Akiyama, T., Wakabayashi, S., Matsushita, M., Sakota, M., Kimura, H., Yuzaki, M., Ko, S. & Ko, M., 2017 Feb 13, In : Scientific Reports. 7, 42367.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Signaling Pathways Relevant to Nerve Growth Factor-induced Upregulation of Transient Receptor Potential M8 Expression

Kayama, Y., Shibata, M., Takizawa, T., Ibata, K., Nakahara, J., Shimizu, T., Toriumi, H., Yuzaki, M. & Suzuki, N., 2017 Dec 26, In : Neuroscience. 367, p. 178-188 11 p.

Research output: Contribution to journalArticle

The C1q complement family of synaptic organizers: not just complementary

Yuzaki, M., 2017 Aug 1, In : Current Opinion in Neurobiology. 45, p. 9-15 7 p.

Research output: Contribution to journalReview article

29 Citations (Scopus)
2016

A Computational Model for the AMPA Receptor Phosphorylation Master Switch Regulating Cerebellar Long-Term Depression

Gallimore, A. R., Aricescu, A. R., Yuzaki, M. & Calinescu, R., 2016 Jan 1, In : PLoS Computational Biology. 12, 1, e1004664.

Research output: Contribution to journalArticle

9 Citations (Scopus)

A GluD Coming-Of-Age Story

Yuzaki, M. & Aricescu, A. R., 2016, (Accepted/In press) In : Trends in Neurosciences.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Allosteric activation of membrane-bound glutamate receptors using coordination chemistry within living cells

Kiyonaka, S., Kubota, R., Michibata, Y., Sakakura, M., Takahashi, H., Numata, T., Inoue, R., Yuzaki, M. & Hamachi, I., 2016 Oct 1, In : Nature Chemistry. 8, 10, p. 958-967 10 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

A novel non-canonical Notch signaling regulates expression of synaptic vesicle proteins in excitatory neurons

Hayashi, Y., Nishimune, H., Hozumi, K., Saga, Y., Harada, A., Yuzaki, M., Iwatsubo, T., Kopan, R. & Tomita, T., 2016 Apr 4, In : Scientific reports. 6, 23969.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Involvement of GluD2 in fear-conditioned bradycardia in mice

Kotajima-Murakami, H., Narumi, S., Yuzaki, M. & Yanagihara, D., 2016 Nov 1, In : PLoS One. 11, 11, e0166144.

Research output: Contribution to journalArticle

Long-term depression at parallel fiber-Purkinje cell synapses

Kohda, K., Kakegawa, W. & Yuzaki, M., 2016 Jan 1, Essentials of Cerebellum and Cerebellar Disorders: A Primer for Graduate Students. Springer International Publishing, p. 329-334 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Physiological functions of D-serine mediated through δ2 glutamate receptors in the cerebellum

Kakegawa, W. & Yuzaki, M., 2016 Jan 1, D-Amino Acids: Physiology, Metabolism, and Application. Springer Japan, p. 65-80 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Roles of Cbln1 in non-motor functions of mice

Otsuka, S., Konno, K., Abe, M., Motohashi, J., Kohda, K., Sakimura, K., Watanabe, M. & Yuzaki, M., 2016 Nov 16, In : Journal of Neuroscience. 36, 46, p. 11801-11816 16 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Structural basis for integration of GluD receptors within synaptic organizer complexes

Elegheert, J., Kakegawa, W., Clay, J. E., Shanks, N. F., Behiels, E., Matsuda, K., Kohda, K., Miura, E., Rossmann, M., Mitakidis, N., Motohashi, J., Chang, V. T., Siebold, C., Greger, I. H., Nakagawa, T., Yuzaki, M. & Aricescu, A. R., 2016 Jul 15, In : Science. 353, 6296, p. 295-300 6 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Transsynaptic Modulation of Kainate Receptor Functions by C1q-like Proteins

Matsuda, K., Budisantoso, T., Mitakidis, N., Sugaya, Y., Miura, E., Kakegawa, W., Yamasaki, M., Konno, K., Uchigashima, M., Abe, M., Watanabe, I., Kano, M., Watanabe, M., Sakimura, K., Aricescu, A. R. & Yuzaki, M., 2016 May 18, In : Neuron. 90, 4, p. 752-767 16 p.

Research output: Contribution to journalArticle

65 Citations (Scopus)
2015

Anterograde C1ql1 signaling is required in order to determine and maintain a single-winner climbing fiber in the mouse cerebellum

Kakegawa, W., Mitakidis, N., Miura, E., Abe, M., Matsuda, K., Takeo, Y. H., Kohda, K., Motohashi, J., Takahashi, A., Nagao, S., Muramatsu, S. I., Watanabe, M., Sakimura, K., Aricescu, A. R. & Yuzaki, M., 2015 Jan 21, In : Neuron. 85, 2, p. 316-329 14 p.

Research output: Contribution to journalArticle

70 Citations (Scopus)

Controlling the Regional Identity of hPSC-Derived Neurons to Uncover Neuronal Subtype Specificity of Neurological Disease Phenotypes

Imaizumi, K., Sone, T., Ibata, K., Fujimori, K., Yuzaki, M., Akamatsu, W. & Okano, H., 2015 Dec 8, In : Stem Cell Reports. 5, 6, p. 1010-1022 13 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Rorα regulates multiple aspects of dendrite development in cerebellar purkinje cells in vivo

Takeo, Y. H., Kakegawa, W., Miura, E. & Yuzaki, M., 2015 Sep 9, In : Journal of Neuroscience. 35, 36, p. 12518-12534 17 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2014

Axonal localization of Ca2+-dependent activator protein for secretion 2 is critical for subcellular locality of brain-derived neurotrophic factor and neurotrophin-3 release affecting proper development of postnatal mouse cerebellum

Sadakata, T., Kakegawa, W., Shinoda, Y., Hosono, M., Katoh-Semba, R., Sekine, Y., Sato, Y., Saruta, C., Ishizaki, Y., Yuzaki, M., Kojima, M. & Furuichi, T., 2014 Jun 12, In : PloS one. 9, 6, e99524.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Cbln1 downregulates the formation and function of inhibitory synapses in mouse cerebellar Purkinje cells

Ito-Ishida, A., Kakegawa, W., Kohda, K., Miura, E., Okabe, S. & Yuzaki, M., 2014 Apr, In : European Journal of Neuroscience. 39, 8, p. 1268-1280 13 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Enriched expression of GluD1 in higher brain regions and its involvement in parallel fiber-interneuron synapse formation in the cerebellum

Konno, K., Matsuda, K., Nakamoto, C., Uchigashima, M., Miyazaki, T., Yamasaki, M., Sakimura, K., Yuzaki, M. & Watanabe, M., 2014 Jan 1, In : Journal of Neuroscience. 34, 22, p. 7412-7424 13 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Neural ECM and synaptogenesis

Heikkinen, A., Pihlajaniemi, T., Faissner, A. & Yuzaki, M., 2014 Jan 1, Progress in Brain Research. Elsevier B.V., p. 29-51 23 p. (Progress in Brain Research; vol. 214).

Research output: Chapter in Book/Report/Conference proceedingChapter

23 Citations (Scopus)

Rab8a and Rab8b are essential for several apical transport pathways but insufficient for ciliogenesis

Sato, T., Iwano, T., Kunii, M., Matsuda, S., Mizuguchi, R., Jung, Y., Hagiwara, H., Yoshihara, Y., Yuzaki, M., Harada, R. & Harada, A., 2014 Jan 1, In : Journal of Cell Science. 127, 2, p. 422-431 10 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

Reprogramming non-human primate somatic cells into functional neuronal cells by defined factors

Zhou, Z., Kohda, K., Ibata, K., Kohyama, J., Akamatsu, W., Yuzaki, M., Okano, H. J., Sasaki, E. & Okano, H., 2014 Apr 3, In : Molecular brain. 7, 1, 24.

Research output: Contribution to journalArticle

15 Citations (Scopus)

The role of Cbln1 on Purkinje cell synapse formation

Ito-Ishida, A., Okabe, S. & Yuzaki, M., 2014 Jun 1, In : Neuroscience Research. 83, p. 64-68 5 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2013

CAPS1 deficiency perturbs dense-core vesicle trafficking and golgi structure and reduces presynaptic release probability in the mouse brain

Sadakata, T., Kakegawa, W., Shinoda, Y., Hosono, M., Katoh-Semba, R., Sekine, Y., Sato, Y., Tanaka, M., Iwasato, T., Itohara, S., Furuyama, K., Kawaguchi, Y., Ishizaki, Y., Yuzaki, M. & Furuichi, T., 2013 Nov 4, In : Journal of Neuroscience. 33, 44, p. 17326-17334 9 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Cerebellar LTD vs. motor learning-Lessons learned from studying GluD2

Yuzaki, M., 2013 Nov 1, In : Neural Networks. 47, p. 36-41 6 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Deletions in GRID2 lead to a recessive syndrome of cerebellar ataxia and tonic upgaze in humans

Hills, L. B., Masri, A., Konno, K., Kakegawa, W., Lam, A. T. N., Lim-Melia, E., Chandy, N., Hill, R. S., Partlow, J. N., Al-Saffar, M., Nasir, R., Stoler, J. M., Barkovich, A. J., Watanabe, M., Yuzaki, M. & Mochida, G. H., 2013 Oct 15, In : Neurology. 81, 16, p. 1378-1386 9 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)