• 1264 Citations
  • 21 h-Index
1993 …2020

Research output per year

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Research Output

  • 1264 Citations
  • 21 h-Index
  • 54 Article
  • 3 Letter
  • 3 Review article
  • 1 Chapter
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Article
2020

A significant association of non-obese non-alcoholic fatty liver disease with sarcopenic obesity

Kashiwagi, K., Takayama, M., Fukuhara, K., Shimizu-Hirota, R., Chu, P. S., Nakamoto, N., Inoue, N., Iwao, Y. & Kanai, T., 2020 Aug, In : Clinical Nutrition ESPEN. 38, p. 86-93 8 p.

Research output: Contribution to journalArticle

Open Access

Potential association of metabolic and musculoskeletal disorders with lumbar intervertebral disc degeneration: Cross-sectional study using medical checkup data

Fujita, N., Ishihara, S., Michikawa, T., Azuma, K., Suzuki, S., Tsuji, O., Nagoshi, N., Okada, E., Yagi, M., Tsuji, T., Takayama, M., Matsumoto, H., Nakamura, M., Matsumoto, M. & Watanabe, K., 2020 May, In : Journal of Orthopaedic Science. 25, 3, p. 384-388 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2019

Spinal epidural lipomatosis is a previously unrecognized manifestation of metabolic syndrome

Ishihara, S., Fujita, N., Azuma, K., Michikawa, T., Yagi, M., Tsuji, T., Takayama, M., Matsumoto, H., Nakamura, M., Matsumoto, M. & Watanabe, K., 2019 Mar 1, In : Spine Journal. 19, 3, p. 493-500 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2018

Carotid plaque score and risk of cardiovascular mortality in the oldest old: Results from the TOOTH study

Hirata, T., Arai, Y., Takayama, M., Abe, Y., Ohkuma, K. & Takebayashi, T., 2018, In : Journal of atherosclerosis and thrombosis. 25, 1, p. 55-64 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Relative validity of brief-type self-administered diet history questionnaire among very old Japanese aged 80 years or older

Kobayashi, S., Yuan, X., Sasaki, S., Osawa, Y., Hirata, T., Abe, Y., Takayama, M., Arai, Y., Masui, Y. & Ishizaki, T., 2018 Jan 1, (Accepted/In press) In : Public Health Nutrition.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2017

Association of kidney dysfunction with asymptomatic cerebrovascular abnormalities in a Japanese population with health checkups

Hayashi, K., Takayama, M., Kanda, T., Kashiwagi, K., Hishikawa, A., Iwao, Y. & Itoh, H., 2017, In : Circulation Journal. 81, 8, p. 1191-1197 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Identification of dietary patterns and their relationships with general and oral health in the very old

Osawa, Y., Arai, Y., Takayama, M., Hirata, T., Kawasaki, M., Abe, Y., Iinuma, T., Sasaki, S. & Hirose, N., 2017, In : Asia Pacific Journal of Clinical Nutrition. 26, 2, p. 262-270 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
8 Citations (Scopus)

Longitudinal association of hypertension and diabetes mellitus with cognitive functioning in a general 70-year-old population: The SONIC study

Ryuno, H., Kamide, K., Gondo, Y., Kabayama, M., Oguro, R., Nakama, C., Yokoyama, S., Nagasawa, M., Maeda-Hirao, S., Imaizumi, Y., Takeya, M., Yamamoto, H., Takeda, M., Takami, Y., Itoh, N., Takeya, Y., Yamamoto, K., Sugimoto, K., Nakagawa, T., Yasumoto, S. & 8 others, Ikebe, K., Inagaki, H., Masui, Y., Takayama, M., Arai, Y., Ishizaki, T., Takahashi, R. & Rakugi, H., 2017 Jul 1, In : Hypertension Research. 40, 7, p. 665-670 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Maintenance of the paraspinal muscles may protect against radiographic knee osteoarthritis

Azuma, K., Sera, Y., Shinjo, T., Takayama, M., Shiomi, E., Momoshima, S., Iwao, Y., Ishida, H. & Matsumoto, H., 2017 Aug 10, In : Open Access Rheumatology: Research and Reviews. 9, p. 151-158 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Perceived swallowing problems and mortality risk in very elderly people ≥85 years old: Results of the Tokyo Oldest Old Survey on Total Health study

Iinuma, T., Hirata, T., Arai, Y., Takayama, M., Abe, Y., Fukumoto, M., Fukui, Y. & Gionhaku, N., 2017, (Accepted/In press) In : Gerodontology.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Relationships of muscle echo intensity with walking ability and physical activity in the very old population

Osawa, Y., Arai, Y., Oguma, Y., Hirata, T., Abe, Y., Azuma, K., Takayama, M. & Hirose, N., 2017 Apr 1, In : Journal of Aging and Physical Activity. 25, 2, p. 189-195 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Satisfaction with dietary life affects oral health-related quality of life and subjective well-being in very elderly people

Iinuma, T., Arai, Y., Takayama, M., Takayama, M., Abe, Y., Osawa, Y., Fukumoto, M., Fukui, Y., Shioda, Y., Hirose, N., Komiyama, K. & Gionhaku, N., 2017, In : Journal of oral science. 59, 2, p. 207-213 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
4 Citations (Scopus)
2016

Association between maximum occlusal force and 3-year all-cause mortality in community-dwelling elderly people

Iinuma, T., Arai, Y., Takayama, M., Abe, Y., Ito, T., Kondo, Y., Hirose, N. & Gionhaku, N., 2016 Sep 1, In : BMC Oral Health. 16, 1, 82.

Research output: Contribution to journalArticle

9 Citations (Scopus)
6 Citations (Scopus)

Differences in the association between high blood pressure and cognitive functioning among the general Japanese population aged 70 and 80 years: The SONIC study

Ryuno, H., Kamide, K., Gondo, Y., Nakama, C., Oguro, R., Kabayama, M., Kawai, T., Kusunoki, H., Yokoyama, S., Imaizumi, Y., Takeya, M., Yamamoto, H., Takeda, M., Takami, Y., Itoh, N., Yamamoto, K., Takeya, Y., Sugimoto, K., Nakagawa, T., Ikebe, K. & 7 others, Inagaki, H., Masui, Y., Ishizaki, T., Takayama, M., Arai, Y., Takahashi, R. & Rakugi, H., 2016 Jul 1, In : Hypertension Research. 39, 7, p. 557-563 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
13 Citations (Scopus)

Effects of the APOE ε4 allele and education on cognitive function in Japanese centenarians

Ishioka, Y. L., Gondo, Y., Fuku, N., Inagaki, H., Masui, Y., Takayama, M., Abe, Y., Arai, Y. & Hirose, N., 2016 Aug 24, (Accepted/In press) In : Age. p. 1-9 9 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2015

Association of visceral fat area, smoking, and alcohol consumption with reflux esophagitis and Barrett's esophagus in Japan

Matsuzaki, J., Suzuki, H., Kobayakawa, M., Inadomi, J. M., Takayama, M., Makino, K., Iwao, Y., Sugino, Y. & Kanai, T., 2015 Jul 30, In : PloS one. 10, 7, e0133865.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Denture wearing during sleep doubles the risk of pneumonia in the very elderly

Iinuma, T., Arai, Y., Abe, Y., Takayama, M., Fukumoto, M., Fukui, Y., Iwase, T., Takebayashi, T., Hirose, N., Gionhaku, N. & Komiyama, K., 2015 Mar 25, In : Journal of Dental Research. 94, p. 28S-36S

Research output: Contribution to journalArticle

56 Citations (Scopus)

Inflammation, But Not Telomere Length, Predicts Successful Ageing at Extreme Old Age: A Longitudinal Study of Semi-supercentenarians

Arai, Y., Martin-Ruiz, C. M., Takayama, M., Abe, Y., Takebayashi, T., Koyasu, S., Suematsu, M., Hirose, N. & von Zglinicki, T., 2015 Oct 1, In : EBioMedicine. 2, 10, p. 1549-1558 10 p.

Research output: Contribution to journalArticle

104 Citations (Scopus)
2014

Physical independence and mortality at the extreme limit of life span: Supercentenarians study in Japan

Arai, Y., Inagaki, H., Takayama, M., Abe, Y., Saito, Y., Takebayashi, T., Gondo, Y. & Hirose, N., 2014 Jan 1, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 69, 4, p. 486-494 9 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
2013

Association of marine-origin N-3 polyunsaturated fatty acids consumption and functional mobility in the community-dwelling oldest old

Takayama, M., Arai, Y., Sasaki, S., Hashimoto, M., Shimizu, K., Abe, Y. & Hirose, N., 2013 Jan 1, In : Journal of Nutrition, Health and Aging. 17, 1, p. 82-89 8 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2012

Maximum occlusal force and physical performance in the oldest old: The Tokyo oldest old survey on total health

Iinuma, T., Arai, Y., Fukumoto, M., Takayama, M., Abe, Y., Asakura, K., Nishiwaki, Y., Takebayashi, T., Iwase, T., Komiyama, K., Gionhaku, N. & Hirose, N., 2012 Jan 1, In : Journal of the American Geriatrics Society. 60, 1, p. 68-76 9 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)
2011

Proteomic analysis of plasma proteins in Japanese semisuper centenarians

Miura, Y., Sato, Y., Arai, Y., Abe, Y., Takayama, M., Toda, T., Hirose, N. & Endo, T., 2011 Jan 1, In : Experimental Gerontology. 46, 1, p. 81-85 5 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
2010

The Tokyo Oldest Old Survey on Total Health (TOOTH): A longitudinal cohort study of multidimensional components of health and well-being

Arai, Y., Iinuma, T., Takayama, M., Takayama, M., Abe, Y., Fukuda, R., Ando, J., Ohta, K., Hanabusa, H., Asakura, K., Nishiwaki, Y., Gondo, Y., Akiyama, H., Komiyama, K., Gionhaku, N. & Hirose, N., 2010 Jun 11, In : BMC Geriatrics. 10, 35.

Research output: Contribution to journalArticle

31 Citations (Scopus)
2009
1 Citation (Scopus)

Cognitive function in Japanese centenarians according to the mini-mental state examination

Inagaki, H., Gondo, Y., Hirose, N., Masui, Y., Kitagawa, K., Arai, Y., Ebihara, Y., Yamamura, K., Takayama, M., Nakazawa, S., Shimizu, K. I. & Homma, A., 2009 Aug 1, In : Dementia and Geriatric Cognitive Disorders. 28, 1, p. 6-12 7 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

The metabolic syndrome, IGF-1, and insulin action

Arai, Y., Kojima, T., Takayama, M. & Hirose, N., 2009 Feb 5, In : Molecular and Cellular Endocrinology. 299, 1, p. 124-128 5 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
2008

Adipose endocrine function, insulin-like growth factor-1 axis, and exceptional survival beyond 100 years of age

Arai, Y., Takayama, M., Gondo, Y., Inagaki, H., Yamamura, K., Nakazawa, S., Kojima, T., Ebihara, Y., Shimizu, K., Masui, Y., Kitagawa, K., Takebayashi, T. & Hirose, N., 2008 Nov, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 63, 11, p. 1209-1218 10 p.

Research output: Contribution to journalArticle

Open Access
52 Citations (Scopus)
2007

Morbidity of Tokyo-area centenarians and its relationship to functional status

Takayama, M., Hirose, N., Arai, Y., Gondo, Y., Shimizu, K., Ebihara, Y., Yamamura, K., Nakazawa, S., Inagaki, H., Masui, Y. & Kitagawa, K., 2007 Jul, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 62, 7, p. 774-782 9 p.

Research output: Contribution to journalArticle

Open Access
53 Citations (Scopus)
2006

Functional status of centenarians in Tokyo, Japan: Developing better phenotypes of exceptional longevity

Gondo, Y., Hirose, N., Arai, Y., Inagaki, H., Masui, Y., Yamamura, K., Shimizu, K. I., Takayama, M., Ebihara, Y., Nakazawa, S. & Kitagawa, K., 2006 Mar, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 61, 3, p. 305-310 6 p.

Research output: Contribution to journalArticle

Open Access
124 Citations (Scopus)
2005

Contribution of an affect-associated gene to human longevity: Prevalence of the long-allele genotype of the serotonin transporter-linked gene in Japanese centenarians

Gondo, Y., Hirose, N., Arai, Y., Yamamura, K., Shimizu, K. I., Takayama, M., Ebihara, Y., Nakazawa, S., Inagaki, H., Masui, Y. & Kitagawa, K., 2005 Nov 1, In : Mechanisms of Ageing and Development. 126, 11, p. 1178-1184 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2004

Association analysis between longevity in the Japanese population and polymorphic variants of genes involved in insulin and insulin-like growth factor 1 signaling pathways

Kojima, T., Kamei, H., Aizu, T., Arai, Y., Takayama, M., Nakazawa, S., Ebihara, Y., Inagaki, H., Masui, Y., Gondo, Y., Sakaki, Y. & Hirose, N., 2004 Nov 1, In : Experimental Gerontology. 39, 11-12 SPEC. ISS., p. 1595-1598 4 p.

Research output: Contribution to journalArticle

87 Citations (Scopus)
2003

Association analysis of the SHC1 gene locus with longevity in the Japanese population

Kamei, H., Adati, N., Arai, Y., Yamamura, K., Takayama, M., Nakazawa, S., Ebihara, Y., Gondo, Y., Akechi, M., Noguchi, T., Hirose, N., Sakaki, Y. & Kojima, T., 2003 Nov 1, In : Journal of Molecular Medicine. 81, 11, p. 724-728 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Deficiency of choresteryl ester transfer protein and gene polymorphisms of lipoprotein lipase and hepatic lipase are not associated with longevity

Arai, Y., Hirose, N., Yamamura, K., Nakazawa, S., Shimizu, K. I., Takayama, M., Ebihara, Y., Homma, S., Gondo, Y., Masui, Y. & Inagaki, H., 2003 Feb 1, In : Journal of Molecular Medicine. 81, 2, p. 102-109 8 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Preconditioning with heat shock further improved functional recovery in young adult but not in middle-aged rat hearts

Honma, Y., Tani, M., Yamamura, K., Takayama, M. & Hasegawa, H., 2003 Mar 1, In : Experimental Gerontology. 38, 3, p. 299-306 8 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
2002

Aging abolishes the cardioprotective effect of combination heat shock and hypoxic preconditioning in reperfused rat hearts

Honma, Y., Tani, M., Takayama, M., Yamamura, K. & Hasegawa, H., 2002 Nov 1, In : Basic Research in Cardiology. 97, 6, p. 489-495 7 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2001
13 Citations (Scopus)

Lipoprotein metabolism in Japanese centenarians: Effects of apolipoprotein E polymorphism and nutritional status

Arai, Y., Hirose, N., Nakazawa, S., Yamamura, K., Shimizu, K. I., Takayama, M., Ebihara, Y., Osono, Y. & Homma, S., 2001 Nov 22, In : Journal of the American Geriatrics Society. 49, 11, p. 1434-1441 8 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Serum insulin-like growth factor-1 in centenarians: Implications of IGF-1 as a rapid turnover protein

Arai, Y., Hirose, N., Yamamura, K., Shimizu, K. I., Takayama, M., Ebihara, Y. & Osono, Y., 2001 Jan 1, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 56, 2, p. M79-M82

Research output: Contribution to journalArticle

Open Access
47 Citations (Scopus)
2000

Ca2+ sensitizer, pimobendan, attenuates myocardial injury in low-flow ischemic but not in total ischemic hearts

Hasegawa, H., Tani, M., Honma, Y., Tamaki, K., Yamamura, K., Takayama, M. & Ebihara, Y., 2000 Nov 25, In : Respiration and Circulation. 48, 11, p. 1165-1170 6 p.

Research output: Contribution to journalArticle

Clinical factors related to the aqueous levels of vascular endothelial growth factor and hepatocyte growth factor in proliferative diabetic retinopathy

Shinoda, K., Ishida, S., Kawashima, S., Wakabayashi, T., Uchita, M., Matsuzaki, T., Takayama, M., Shinmura, K. & Yamada, M., 2000 Jan 1, In : Current Eye Research. 21, 2, p. 655-661 7 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Clinical Role of Vascular Endothelial Growth Factor (VEGF) and Hepatocyte Growth Factor (HGF) in Type-2 Diabetic Patients

Takayama, M., Shinmura, K., Hasegawa, H., Tani, M., Wakabayashi, T., Shinoda, K., Ishida, S. & Yamada, M., 2000, In : Journal of the Japan Diabetes Society. 43, 5, p. 347-354 8 p.

Research output: Contribution to journalArticle

1999

Comparison of the levels of hepatocyte growth factor and vascular endothelial growth factor in aqueous fluid and serum with grades of retinopathy in patients with diabetes mellitus

Shinoda, K., Ishida, S., Kawashima, S., Wakabayashi, T., Matsuzaki, T., Takayama, M., Shinmura, K. & Yamada, M., 1999, In : British Journal of Ophthalmology. 83, 7, p. 834-837 4 p.

Research output: Contribution to journalArticle

Open Access
67 Citations (Scopus)

Loss of protection by hypoxic preconditioning in aging Fischer 344 rat hearts related to myocardial glycogen content and Na+ imbalance

Tani, M., Honma, Y., Takayama, M., Hasegawa, H., Shinmura, K., Ebihara, Y. & Tamaki, K., 1999 Mar 1, In : Cardiovascular Research. 41, 3, p. 594-602 9 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)
1998

Low concentrations of adenosine receptor blocker decrease protection by hypoxic preconditioning in ischemic rat hearts

Tani, M., Suganuma, Y., Takayama, M., Hasegawa, H., Shinmura, K., Ebihara, Y. & Tamaki, K., 1998 Mar, In : Journal of Molecular and Cellular Cardiology. 30, 3, p. 617-626 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)