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Research Output 1981 2019

  • 5917 Citations
  • 26 h-Index
  • 50 Article
  • 1 Chapter
2019

Melon GliSODin® prevents diet-induced NASH onset by reducing fat synthesis and improving liver function

Nakamura, A., Kitamura, N., Yokoyama, Y., Uchida, S., Kumadaki, K., Tsubota, K. & Watanabe, M., 2019 Aug 1, In : Nutrients. 11, 8, 1779.

Research output: Contribution to journalArticle

Open Access
Cucurbitaceae
liver function
Fatty Liver
melons
Fats
2018
15 Citations (Scopus)

Bile acid metabolism regulated by the gut microbiota promotes non-alcoholic steatohepatitis-associated hepatocellular carcinoma in mice

Yamada, S., Takashina, Y., Watanabe, M., Nagamine, R., Saito, Y., Kamada, N. & Saito, H., 2018 Jan 1, In : Oncotarget. 9, 11, p. 9925-9939 15 p.

Research output: Contribution to journalArticle

Fatty Liver
Bile Acids and Salts
Hepatocellular Carcinoma
Anti-Bacterial Agents
Liver
5 Citations (Scopus)

Claudin-3 regulates bile canalicular paracellular barrier and cholesterol gallstone core formation in mice

Tanaka, H., Imasato, M., Yamazaki, Y., Matsumoto, K., Kunimoto, K., Delpierre, J., Meyer, K., Zerial, M., Kitamura, N., Watanabe, M., Tamura, A. & Tsukita, S., 2018 Jan 1, (Accepted/In press) In : Journal of Hepatology.

Research output: Contribution to journalArticle

Claudin-3
Gallstones
Bile
Cholesterol
Ions
9 Citations (Scopus)

Lithocholic acid, a bacterial metabolite reduces breast cancer cell proliferation and aggressiveness

Mikó, E., Vida, A., Kovács, T., Ujlaki, G., Trencsényi, G., Márton, J., Sári, Z., Kovács, P., Boratkó, A., Hujber, Z., Csonka, T., Antal-Szalmás, P., Watanabe, M., Gombos, I., Csoka, B., Kiss, B., Vígh, L., Szabó, J., Méhes, G., Sebestyén, A. & 2 others, Goedert, J. J. & Bai, P., 2018 Jan 1, (Accepted/In press) In : Biochimica et Biophysica Acta - Bioenergetics.

Research output: Contribution to journalArticle

Lithocholic Acid
Cell proliferation
Metabolites
Cell Proliferation
Breast Neoplasms
2017
9 Citations (Scopus)

Bile acid binding resin prevents fat accumulation through intestinal microbiota in high-fat diet-induced obesity in mice

Kusumoto, Y., Irie, J., Iwabu, K., Tagawa, H., Itoh, A., Kato, M., Kobayashi, N., Tanaka, K., Kikuchi, R., Fujita, M., Nakajima, Y., Morimoto, K., Sugizaki, T., Yamada, S., Kawai, T., Watanabe, M., Oike, Y. & Itoh, H., 2017 Jun 1, In : Metabolism: Clinical and Experimental. 71, p. 1-6 6 p.

Research output: Contribution to journalArticle

High Fat Diet
Bile Acids and Salts
Obesity
Fats
Fat-Restricted Diet

Bile acids and metabolic syndrome

Taoka, H. & Watanabe, M., 2017 Apr 3, Bile Acids in Gastroenterology: Basic and Clinical. Springer Japan, p. 193-209 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Bile Acids and Salts
Metabolic Networks and Pathways
Incretins
Glucose
Bariatric Surgery
5 Citations (Scopus)

Neuroprotective role of retinal SIRT3 against acute photo-stress

Ban, N., Ozawa, Y., Osada, H., Lin, J. B., Toda, E., Watanabe, M., Yuki, K., Kubota, S., Apte, R. S. & Tsubota, K., 2017 Dec 1, In : npj Aging and Mechanisms of Disease. 3, 1, 19.

Research output: Contribution to journalArticle

Reactive Oxygen Species
Retina
Endoplasmic Reticulum Stress
Light
Photoreceptor Cells
2016
6 Citations (Scopus)

Intestinal bile acid composition modulates prohormone convertase 1β (PC1/3) expression and consequent GLP-1 production in male mice

Morimoto, K., Watanabe, M., Sugizaki, T., Irie, J. & Itoh, H., 2016 Mar 1, In : Endocrinology. 157, 3, p. 1071-1081 11 p.

Research output: Contribution to journalArticle

Proprotein Convertase 1
Glucagon-Like Peptide 1
Bile Acids and Salts
Gene Expression
Hypoglycemic Agents
2015
8 Citations (Scopus)

Bile acid binding resin improves hepatic insulin sensitivity by reducing cholesterol but not triglyceride levels in the liver

Tagawa, H., Irie, J., Itoh, A., Kusumoto, Y., Kato, M., Kobayashi, N., Tanaka, K., Morinaga, R., Fujita, M., Nakajima, Y., Morimoto, K., Sugizaki, T., Kawano, Y., Yamada, S., Kawai, T., Watanabe, M. & Itoh, H., 2015 Jul 1, In : Diabetes Research and Clinical Practice. 109, 1, p. 85-94 10 p.

Research output: Contribution to journalArticle

Bile Acids and Salts
Insulin Resistance
Triglycerides
Cholesterol
Liver
2014
9 Citations (Scopus)

Aerobic exercise increases tear secretion in type 2 diabetic mice

Sano, K., Kawashima, M., Ito, A., Inaba, T., Morimoto, K., Watanabe, M. & Tsubota, K., 2014, In : Investigative Ophthalmology and Visual Science. 55, 7, p. 4287-4294 8 p.

Research output: Contribution to journalArticle

Tears
Exercise
Inbred C57BL Mouse
Lysine
Oxidative Stress
32 Citations (Scopus)

Claudin 2 deficiency reduces bile flow and increases susceptibility to cholesterol gallstone disease in mice

Matsumoto, K., Imasato, M., Yamazaki, Y., Tanaka, H., Watanabe, M., Eguchi, H., Nagano, H., Hikita, H., Tatsumi, T., Takehara, T., Tamura, A. & Tsukita, S., 2014 Nov 1, In : Gastroenterology. 147, 5, p. 1134-1145.e10

Research output: Contribution to journalArticle

Claudin-2
Gallstones
Bile
Cholesterol
Knockout Mice
11 Citations (Scopus)

Cysteine sulfinic acid decarboxylase regulation: A role for farnesoid X receptor and small heterodimer partner in murine hepatic taurine metabolism

Kerr, T. A., Matsumoto, Y., Matsumoto, H., Xie, Y., Hirschberger, L. L., Stipanuk, M. H., Anakk, S., Moore, D. D., Watanabe, M., Kennedy, S. & Davidson, N. O., 2014 Oct 1, In : Hepatology Research. 44, 10, p. E218-E228

Research output: Contribution to journalArticle

sulfoalanine decarboxylase
Taurine
Bile Acids and Salts
Messenger RNA
Liver
16 Citations (Scopus)

The niemann-Pick C1 like 1 (NPC1L1) inhibitor ezetimibe improves metabolic disease via decreased liver X receptor (LXR) activity in liver of obese male mice

Sugizaki, T., Watanabe, M., Horai, Y., Kaneko-Iwasaki, N., Arita, E., Miyazaki, T., Morimoto, K., Honda, A., Irie, J. & Itoh, H., 2014, In : Endocrinology. 155, 8, p. 2810-2819 10 p.

Research output: Contribution to journalArticle

Obese Mice
Metabolic Diseases
Liver
Oleic Acid
Insulin
62 Citations (Scopus)

Vitamin D and energy homeostasis - Of mice and men

Bouillon, R., Carmeliet, G., Lieben, L., Watanabe, M., Perino, A., Auwerx, J., Schoonjans, K. & Verstuyf, A., 2014 Feb, In : Nature Reviews Endocrinology. 10, 2, p. 79-87 9 p.

Research output: Contribution to journalArticle

Vitamin D
Calcitriol Receptors
Homeostasis
Obesity
Cytoplasmic and Nuclear Receptors
2013
45 Citations (Scopus)

Bile acids increase levels of microRNAs 221 and 222, leading to degradation of CDX2 during esophageal carcinogenesis

Matsuzaki, J., Suzuki, H., Tsugawa, H., Watanabe, M., Hossain, S., Arai, E., Saito, Y., Sekine, S., Akaike, T., Kanai, Y., Mukaisho, K. I., Auwerx, J. & Hibi, T., 2013 Dec, In : Gastroenterology. 145, 6, p. 1300-1311 12 p.

Research output: Contribution to journalArticle

Bile Acids and Salts
MicroRNAs
Carcinogenesis
Adenocarcinoma
Barrett Esophagus
14 Citations (Scopus)

Calorie restriction (CR) and CR mimetics for the prevention and treatment of age-related eye disorders

Kawashima, M., Ozawa, Y., Shinmura, K., Inaba, T., Nakamura, S., Kawakita, T., Watanabe, M. & Tsubota, K., 2013 Oct, In : Experimental Gerontology. 48, 10, p. 1096-1100 5 p.

Research output: Contribution to journalArticle

Eye Diseases
Aging of materials
Macular Degeneration
Diabetic Retinopathy
Animal Models
2 Citations (Scopus)

Developments in understanding bile acid metabolism

Morimoto, K., Itoh, H. & Watanabe, M., 2013 Jan, In : Expert Review of Endocrinology and Metabolism. 8, 1, p. 59-69 11 p.

Research output: Contribution to journalArticle

Bile Acids and Salts
Poisons
Cytoplasmic and Nuclear Receptors
G-Protein-Coupled Receptors
Lipid Metabolism
13 Citations (Scopus)

Light-dark condition regulates sirtuin mRNA levels in the retina

Ban, N., Ozawa, Y., Inaba, T., Miyake, S., Watanabe, M., Shinmura, K. & Tsubota, K., 2013 Nov, In : Experimental Gerontology. 48, 11, p. 1212-1217 6 p.

Research output: Contribution to journalArticle

Sirtuins
Retina
Light
Messenger RNA
Liver
13 Citations (Scopus)

Tysnd1 Deficiency in Mice Interferes with the Peroxisomal Localization of PTS2 Enzymes, Causing Lipid Metabolic Abnormalities and Male Infertility

Mizuno, Y., Ninomiya, Y., Nakachi, Y., Iseki, M., Iwasa, H., Akita, M., Tsukui, T., Shimozawa, N., Ito, C., Toshimori, K., Nishimukai, M., Hara, H., Maeba, R., Okazaki, T., Alodaib, A. N. A., Amoudi, M. A., Jacob, M., Alkuraya, F. S., Horai, Y., Watanabe, M. & 7 others, Motegi, H., Wakana, S., Noda, T., Kurochkin, I. V., Mizuno, Y., Schönbach, C. & Okazaki, Y., 2013 Feb, In : PLoS Genetics. 9, 2, e1003286.

Research output: Contribution to journalArticle

infertility
Male Infertility
male fertility
abnormality
Trypsin
2012
65 Citations (Scopus)

Bile Acid Binding Resin Improves Metabolic Control through the Induction of Energy Expenditure

Watanabe, M., Morimoto, K., Houten, S. M., Kaneko-Iwasaki, N., Sugizaki, T., Horai, Y., Mataki, C., Sato, H., Murahashi, K., Arita, E., Schoonjans, K., Suzuki, T., Itoh, H. & Auwerx, J., 2012 Aug 29, In : PLoS One. 7, 8, e38286.

Research output: Contribution to journalArticle

bile acids
Bile Acids and Salts
energy expenditure
Energy Metabolism
resins
49 Citations (Scopus)

Bile acids induce monocyte differentiation toward interleukin-12 hypo-producing dendritic cells via a TGR5-dependent pathway

Ichikawa, R., Takayama, T., Yoneno, K., Kamada, N., Kitazume, M. T., Higuchi, H., Matsuoka, K., Watanabe, M., Itoh, H., Kanai, T., Hisamatsu, T. & Hibi, T., 2012 Jun, In : Immunology. 136, 2, p. 153-162 10 p.

Research output: Contribution to journalArticle

Interleukin-12
Bile Acids and Salts
Dendritic Cells
Monocytes
Cytoplasmic and Nuclear Receptors
30 Citations (Scopus)

Dietary lactoferrin alleviates age-related lacrimal gland dysfunction in mice

Kawashima, M., Kawakita, T., Inaba, T., Okada, N., Ito, M., Shimmura, S., Watanabe, M., Shinmura, K. & Tsubota, K., 2012 Mar 27, In : PLoS One. 7, 3, e33148.

Research output: Contribution to journalArticle

lacrimal apparatus
Lacrimal Apparatus
Lactoferrin
lactoferrin
Tears
102 Citations (Scopus)

TGR5 potentiates GLP-1 secretion in response to anionic exchange resins

Harach, T., Pols, T. W. H., Nomura, M., Maida, A., Watanabe, M., Auwerx, J. & Schoonjans, K., 2012, In : Scientific Reports. 2, 430.

Research output: Contribution to journalArticle

Glucagon-Like Peptide 1
Colon
G-Protein-Coupled Receptors
Bile Acids and Salts
Animal Models
23 Citations (Scopus)

The antiaging approach for the treatment of dry eye

Tsubota, K., Kawashima, M., Inaba, T., Dogru, M., Matsumoto, Y., Ishida, R., Kaido, M., Kojima, T., Uchino, M., Uchino, Y., Ogawa, Y., Nakamura, S., Higuchi, A., Shinmura, K., Watanabe, M. & Kawakita, T., 2012 Nov, In : Cornea. 31, 11 SUPPL.1

Research output: Contribution to journalArticle

Free Radicals
Therapeutics
Ophthalmic Solutions
Tears
Patient Satisfaction
2011
52 Citations (Scopus)

Combined deletion of Fxr and Shp in mice induces Cyp17a1 and results in juvenile onset cholestasis

Anakk, S., Watanabe, M., Ochsner, S. A., McKenna, N. J., Finegold, M. J. & Moore, D. D., 2011 Jan 4, In : Journal of Clinical Investigation. 121, 1, p. 86-95 10 p.

Research output: Contribution to journalArticle

Cholestasis
Bile Acids and Salts
Knockout Mice
Liver
Wounds and Injuries
5 Citations (Scopus)

Dietary cholesterol reduces plasma triacylglycerol in apolipoprotein E-null mice: Suppression of lipin-1 and -2 in the glycerol-3-phosphate pathway

Obama, T., Nagaoka, S., Akagi, K., Kato, R., Horiuchi, N., Horai, Y., Aiuchi, T., Arata, S., Yamaguchi, T., Watanabe, M. & Itabe, H., 2011, In : PLoS One. 6, 8, e22917.

Research output: Contribution to journalArticle

Dietary Cholesterol
apolipoprotein E
Apolipoproteins E
glycerol
Liver
122 Citations (Scopus)

Loss of claudin-15, but not claudin-2, causes Na+ deficiency and glucose malabsorption in mouse small intestine

Tamura, A., Hayashi, H., Imasato, M., Yamazaki, Y., Hagiwara, A., Wada, M., Noda, T., Watanabe, M., Suzuki, Y. & Tsukita, S., 2011 Mar, In : Gastroenterology. 140, 3, p. 913-923 11 p.

Research output: Contribution to journalArticle

Claudin-2
Small Intestine
Glucose
Knockout Mice
Homeostasis
142 Citations (Scopus)

Lowering bile acid pool size with a synthetic farnesoid X receptor (FXR) agonist induces obesity and diabetes through reduced energy expenditure

Watanabe, M., Horai, Y., Houten, S. M., Morimoto, K., Sugizaki, T., Arita, E., Mataki, C., Sato, H., Tanigawara, Y., Schoonjans, K., Itoh, H. & Auwerx, J., 2011 Jul 29, In : Journal of Biological Chemistry. 286, 30, p. 26913-26920 8 p.

Research output: Contribution to journalArticle

Medical problems
Bile Acids and Salts
Energy Metabolism
Obesity
High Fat Diet
2009
125 Citations (Scopus)

Serum bile acid along with plasma incretins and serum high-molecular weight adiponectin levels are increased after bariatric surgery

Nakatani, H., Kasama, K., Oshiro, T., Watanabe, M., Hirose, H. & Itoh, H., 2009 Oct, In : Metabolism: Clinical and Experimental. 58, 10, p. 1400-1407 8 p.

Research output: Contribution to journalArticle

Incretins
Bariatric Surgery
Adiponectin
Bile Acids and Salts
Molecular Weight
2008
48 Citations (Scopus)

Loss of orphan receptor small heterodimer partner sensitizes mice to liver injury from obstructive cholestasis

Young, J. P., Qatanani, M., Chua, S. S., LaRey, J. L., Johnson, S. A., Watanabe, M., Moore, D. D. & Yoon, K. L., 2008 May, In : Hepatology. 47, 5, p. 1578-1586 9 p.

Research output: Contribution to journalArticle

Cholestasis
Bile Acids and Salts
Ligation
Bile Ducts
Bile
Retinoid X Receptors
Poly(ADP-ribose) Polymerases
PPAR gamma
Adipocytes
Adipose Tissue
2007

Bile Acids Control Lipogenesis and Energy Metabolism

Watanabe, M., 2007, In : Japanese Journal of Clinical Chemistry. 36, 3, p. 215-227 13 p.

Research output: Contribution to journalArticle

Lipogenesis
Bile Acids and Salts
Energy Metabolism
74 Citations (Scopus)

Peroxisome Proliferator-activated Receptor (PPAR)-2 controls adipocyte differentiation and adipose tissue function through the regulation of the activity of the retinoid X receptor/PPARγ heterodimer

Bai, P., Houten, S. M., Huber, A., Schreiber, V., Watanabe, M., Kiss, B., De Murcia, G., Auwerx, J. & Ménissier-De Murcia, J., 2007 Dec 28, In : Journal of Biological Chemistry. 282, 52, p. 37738-37746 9 p.

Research output: Contribution to journalArticle

Retinoid X Receptors
Peroxisome Proliferator-Activated Receptors
Adipocytes
Adipose Tissue
Poly(ADP-ribose) Polymerases
2006
1149 Citations (Scopus)

Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation

Watanabe, M., Houten, S. M., Mataki, C., Christoffolete, M. A., Kim, B. W., Sato, H., Messaddeq, N., Harney, J. W., Ezaki, O., Kodama, T., Schoonjans, K., Bianco, A. C. & Auwerx, J., 2006 Jan 26, In : Nature. 439, 7075, p. 484-489 6 p.

Research output: Contribution to journalArticle

Bile Acids and Salts
Thyroid Hormones
Energy Metabolism
Cytoplasmic and Nuclear Receptors
Homeostasis
346 Citations (Scopus)

Endocrine functions of bile acids

Houten, S. M., Watanabe, M. & Auwerx, J., 2006 Apr 5, In : EMBO Journal. 25, 7, p. 1419-1425 7 p.

Research output: Contribution to journalArticle

Bile Acids and Salts
Cholesterol
Homeostasis
Enterohepatic Circulation
Molecules
2004
1178 Citations (Scopus)

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

Um, S. H., Frigerio, F., Watanabe, M., Picard, F., Joaquin, M., Sticker, M., Fumagalli, S., Allegrini, P. R., Kozma, S. C., Auwerx, J. & Thomas, G., 2004 Sep 9, In : Nature. 431, 7005, p. 200-205 6 p.

Research output: Contribution to journalArticle

Ribosomal Protein S6 Kinases
Insulin Resistance
Obesity
Diet
Insulin
700 Citations (Scopus)

Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c

Watanabe, M., Houten, S. M., Wang, L., Moschetta, A., Mangelsdorf, D. J., Heyman, R. A., Moore, D. D. & Auwerx, J., 2004 Jan 1, In : Journal of Clinical Investigation. 113, 10, p. 1408-1418 11 p.

Research output: Contribution to journalArticle

Sterol Regulatory Element Binding Protein 1
Bile Acids and Salts
Cholic Acid
Triglycerides
Hypertriglyceridemia
4 Citations (Scopus)

Erratum: Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity (Nature (2004) 431 (200-205))

Sung, H. U., Frigerio, F., Watanabe, M., Picard, F., Joaquin, M., Sticker, M., Fumagalli, S., Allegrini, P. R., Kozma, S. C., Auwerx, J. & Thomas, G., 2004 Sep 23, In : Nature. 431, 7007, p. 485 1 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)

Impaired pancreatic growth, β cell mass, and β cell function in E2F1-7-/- mice

Fajas, L., Annicotte, J. S., Miard, S., Sarruf, D., Watanabe, M. & Auwerx, J., 2004 Jan 1, In : Journal of Clinical Investigation. 113, 9, p. 1288-1295 8 p.

Research output: Contribution to journalArticle

Glucose Intolerance
Insulin
Growth
Homeostasis
Glucose

Impaired pancreatic growth, β cell mass, and β cell function in E2F1-7-/- mice

Fajas, L., Annicotte, J. S., Miard, S., Sarruf, D., Watanabe, M. & Auwerx, J., 2004 May, In : Journal of Clinical Investigation. 113, 9, p. 1288-1295 8 p.

Research output: Contribution to journalArticle

Glucose Intolerance
Insulin
Growth
Homeostasis
Glucose
56 Citations (Scopus)

Ligand-dependent contribution of RXRβ to cholesterol homeostasis in Sertoli cells

Mascrez, B., Ghyselinck, N. B., Watanabe, M., Annicotte, J. S., Chambon, P., Auwerx, J. & Mark, M., 2004 Mar, In : EMBO Reports. 5, 3, p. 285-290 6 p.

Research output: Contribution to journalArticle

Retinoid X Receptors
Sertoli Cells
Homeostasis
Cholesterol
Ligands
2003
637 Citations (Scopus)

Activation of peroxisome proliferator-activated receptor δ induces fatty acid β-oxidation in skeletal muscle and attenuates metabolic syndrome

Tanaka, T., Yamamoto, J., Iwasaki, S., Asaba, H., Hamura, H., Ikeda, Y., Watanabe, M., Magoori, K., Ioka, R. X., Tachibana, K., Watanabe, Y., Uchiyama, Y., Sumi, K., Iguchi, H., Ito, S., Doi, T., Hamakubo, T., Naito, M., Auwerx, J., Yanagisawa, M. & 2 others, Kodama, T. & Sakai, J., 2003 Dec 23, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 26, p. 15924-15929 6 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Skeletal Muscle
Fatty Acids
Skeletal Muscle Fibers
Insulin Resistance
138 Citations (Scopus)

Compensation by the muscle limits the metabolic consequences of lipodystrophy in PPARγ hypomorphic mice

Koutnikova, H., Cock, T. A., Watanabe, M., Houten, S. M., Champy, M. F., Dierich, A. & Auwerx, J., 2003 Nov 25, In : Proceedings of the National Academy of Sciences of the United States of America. 100, SUPPL. 2, p. 14457-14462 6 p.

Research output: Contribution to journalArticle

Lipodystrophy
Peroxisome Proliferator-Activated Receptors
Muscles
White Adipose Tissue
Lipids
2002
45 Citations (Scopus)

Distribution and partial characterisation of IgG Fc binding protein in various mucin producing cells and body fluids

Kobayashi, K., Ogata, H., Morikawa, M., Iijima, S., Harada, N., Yoshida, T., Brown, W. R., Inoue, N., Hamada, Y., Ishii, H., Watanabe, M. & Hibi, T., 2002, In : Gut. 51, 2, p. 169-176 8 p.

Research output: Contribution to journalArticle

Body Fluids
Mucins
Carrier Proteins
Immunoglobulin G
Mucus
1996
49 Citations (Scopus)

Deletion mapping on chromosome 1p in well-differentiated gastric cancer

Ezaki, T., Yanagisawa, A., Ohta, K., Aiso, S., Watanabe, M., Hibi, T., Kato, Y., Nakajima, T., Ariyama, T., Inazawa, J., Nakamura, Y. & Horii, A., 1996, In : British Journal of Cancer. 73, 4, p. 424-428 5 p.

Research output: Contribution to journalArticle

Chromosome Mapping
Tumor Suppressor Genes
Microsatellite Repeats
Stomach Neoplasms
Loss of Heterozygosity
1995
337 Citations (Scopus)

Induction of the acyl-coenzyme A synthetase gene by fibrates and fatty acids is mediated by a peroxisome proliferator response element in the C promoter

Schoonjans, K., Watanabe, M., Suzuki, H., Mahfoudi, A., Krey, G., Wahli, W., Grimaldi, P., Staels, B., Yamamoto, T. & Auwerx, J., 1995, In : Journal of Biological Chemistry. 270, 33, p. 19269-19276 8 p.

Research output: Contribution to journalArticle

Coenzyme A Ligases
Peroxisome Proliferators
Fibric Acids
Response Elements
Fatty Acids
1994
46 Citations (Scopus)

Enzyme linked immunosorbent assay (ELISA) and immunoprecipitation studies on anti-goblet cell antibody using a mucin producing cell line in patients with inflammatory bowel disease

Hibi, T., Ohara, M., Kobayashi, K., Brown, W. R., Toda, K., Takaishi, H., Hosoda, Y., Hayashi, A., Iwao, Y., Watanabe, M., Aiso, S., Kawai, Y. & Tsuchiya, M., 1994 Feb, In : Gut. 35, 2, p. 224-230 7 p.

Research output: Contribution to journalArticle

Goblet Cells
Mucins
Inflammatory Bowel Diseases
Immunoprecipitation
Enzyme-Linked Immunosorbent Assay
1992
4 Citations (Scopus)

Rapid Communication - Quantitative analysis of intercellular communication in colon cancer cells (Caco-2) by the scrape-loading/dye transfer assay

Hara, A., Hibil, T., Yoshioka, M., Hayashi, A., Toda, K., Suzuki, T., Kameda, Y., Ueda, F., Watanabe, M. & Tsuchiya, M., 1992 Aug, In : Gastroenterologia Japonica. 27, 4, p. 560 1 p.

Research output: Contribution to journalArticle

Antitumor Drug Screening Assays
Neoplastic Cell Transformation
Cultured Tumor Cells
Intercellular Junctions
Caco-2 Cells
1990
47 Citations (Scopus)

In vitro anticolon antibody production by mucosal or peripheral blood lymphocytes from patients with ulcerative colitis

Hibi, T., Ohara, M., Toda, K., Hara, A., Ogata, H., Iwao, Y., Watanabe, N., Watanabe, M., Hamada, Y., Kobayashi, K., Aiso, S., Tsuchiya, M., Ohara, M., Toda, K. & Watanabe, N., 1990, In : Gut. 31, 12, p. 1371-1376 6 p.

Research output: Contribution to journalArticle

Ulcerative Colitis
Antibody Formation
Lymphocytes
Antibodies
Mucous Membrane
1987
9 Citations (Scopus)

Alteration of T cell maturation and proliferation in the mouse thymus induced by serum factors from patients with ulcerative colitis

Watanabe, M., Aiso, S., Hibi, T., Iwao, Y., Yoshida, T., Asakura, H., Tsuru, S. & Tsuchiya, M., 1987, In : Clinical and Experimental Immunology. 68, 3, p. 596-604 9 p.

Research output: Contribution to journalArticle

Ulcerative Colitis
Thymus Gland
Cell Proliferation
T-Lymphocytes
Serum