• 3097 Citations
  • 32 h-Index
1993 …2020

Research output per year

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Research Output

  • 3097 Citations
  • 32 h-Index
  • 84 Article
  • 4 Review article
  • 1 Comment/debate
  • 1 Letter
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Article
2020

Mucosal concentrations of N-acetyl-5-aminosalicylic acid related to endoscopic activity in ulcerative colitis patients with mesalamine

Fukuda, T., Naganuma, M., Takabayashi, K., Hagihara, Y., Tanemoto, S., Nomura, E., Yoshimatsu, Y., Sugimoto, S., Nanki, K., Mizuno, S., Mikami, Y., Fukuhara, K., Sujino, T., Mutaguchi, M., Inoue, N., Ogata, H., Iwao, Y., Abe, T. & Kanai, T., 2020 Jan 1, (Accepted/In press) In : Journal of Gastroenterology and Hepatology (Australia).

Research output: Contribution to journalArticle

Open Access
2019

Efficacy of therapeutic intervention for patients with an ulcerative colitis mayo endoscopic score of 1

Fukuda, T., Naganuma, M., Sugimoto, S., Ono, K., Nanki, K., Mizuno, S., Hukuhara, K., Mutaguchi, M., Nakazato, Y., Takabayashi, K., Inoue, N., Ogata, H., Iwao, Y. & Kanai, T., 2019 Mar 14, In : Inflammatory bowel diseases. 25, 4, p. 782-788 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Pancreatic fat content may increase the risk of imaging progression in low-risk branch duct intraductal papillary mucinous neoplasm

Kashiwagi, K., Minami, K., Seino, T., Hirata, K., Iwasaki, E., Inoue, N., Iwao, Y. & Kanai, T., 2019 Jan 1, (Accepted/In press) In : Journal of Digestive Diseases.

Research output: Contribution to journalArticle

2018

5-Aminosalicylic acid aggravates colitis mimicking exacerbation of ulcerative colitis

Miyoshi, J., Matsuoka, K., Yoshida, A., Naganuma, M., Hisamatsu, T., Yajima, T., Inoue, N., Okamoto, S., Iwao, Y., Ogata, H., Ueno, F., Hibi, T. & Kanai, T., 2018 Oct 1, In : Intestinal Research. 16, 4, p. 635-640 6 p.

Research output: Contribution to journalArticle

Pancreatic Fat Content Detected by Computed Tomography and Its Significant Relationship with Intraductal Papillary Mucinous Neoplasm

Kashiwagi, K., Seino, T., Fukuhara, S., Minami, K., Horibe, M., Iwasaki, E., Takaishi, H., Itoh, K., Sugino, Y., Inoue, N., Iwao, Y. & Kanai, T., 2018 Oct 1, In : Pancreas. 47, 9, p. 1087-1092 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2017

Endocytoscopy can be used to assess histological healing in ulcerative colitis

Nakazato, Y., Naganuma, M., Sugimoto, S., Bessho, R., Arai, M., Kiyohara, H., Ono, K., Nanki, K., Mutaguchi, M., Mizuno, S., Kobayashi, T., Hosoe, N., Shimoda, M., Abe, T., Inoue, N., Ogata, H., Iwao, Y. & Kanai, T., 2017 Mar 13, (Accepted/In press) In : Endoscopy.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Endoscopic morphologic features of ulcerative colitis–associated dysplasia classified according to the SCENIC consensus statement

Sugimoto, S., Naganuma, M., Iwao, Y., Matsuoka, K., Shimoda, M., Mikami, S., Mizuno, S., Nakazato, Y., Nanki, K., Inoue, N., Ogata, H. & Kanai, T., 2017 Mar 1, In : Gastrointestinal Endoscopy. 85, 3, p. 639-646.e2

Research output: Contribution to journalArticle

13 Citations (Scopus)

Limited identification of dual-time-point positron emission tomography/computed tomography in advanced colorectal neoplasms

Kashiwagi, K., Nakazato, Y., Arai, M., Iwasaki, E., Naganuma, M., Inoue, N., Iwao, Y., Ogata, H., Murakami, K. & Kanai, T., 2017, In : Internal Medicine. 56, 11, p. 1287-1292 6 p.

Research output: Contribution to journalArticle

Long-term safety and efficacy of adalimumab for intestinal Behçet's disease in the open label study following a phase 3 clinical trial

Inoue, N., Kobayashi, K., Naganuma, M., Hirai, F., Ozawa, M., Arikan, D., Huang, B., Robinson, A. M., Thakkar, R. B. & Hibi, T., 2017, In : Intestinal Research. 15, 3, p. 395-401 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Polyp detection rate in transverse and sigmoid colon significantly increases with longer withdrawal time during screening colonoscopy

Kashiwagi, K., Inoue, N., Yoshida, T., Bessyo, R., Yoneno, K., Imaeda, H., Ogata, H., Kanai, T., Sugino, Y. & Iwao, Y., 2017 Mar 1, In : PLoS One. 12, 3, e0174155.

Research output: Contribution to journalArticle

8 Citations (Scopus)

The impact of visceral adipose tissue as best predictor for difficult colonoscopy and the clinical utility of a long small-caliber scope as rescue

Kashiwagi, K., Inoue, N., Yoshida, T., Bessho, R., Yoneno, K., Imaeda, H., Ogata, H., Kanai, T., Sugino, Y. & Iwao, Y., 2017 Dec 1, In : PLoS One. 12, 12, e0189817.

Research output: Contribution to journalArticle

1 Citation (Scopus)

The risk factor of clinical relapse in ulcerative colitis patients with low dose 5-aminosalicylic acid as maintenance therapy: A report from the IBD registry

Fukuda, T., Naganuma, M., Sugimoto, S., Nanki, K., Mizuno, S., Mutaguchi, M., Nakazato, Y., Inoue, N., Ogata, H., Iwao, Y. & Kanai, T., 2017 Nov 1, In : PLoS One. 12, 11, e0187737.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2016

Clinical Efficacy and Safety of Oral Qing-Dai in Patients with Ulcerative Colitis: A Single-Center Open-Label Prospective Study

Sugimoto, S., Naganuma, M., Kiyohara, H., Arai, M., Ono, K., Mori, K., Saigusa, K., Nanki, K., Takeshita, K., Takeshita, T., Mutaguchi, M., Mizuno, S., Bessho, R., Nakazato, Y., Hisamatsu, T., Inoue, N., Ogata, H., Iwao, Y. & Kanai, T., 2016 Mar 10, (Accepted/In press) In : Digestion. p. 193-201 9 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Endoscopic Severity Predicts Long-Term Prognosis in Crohn's Disease Patients with Clinical Remission

Naganuma, M., Hisamatsu, T., Matsuoka, K., Kiyohara, H., Arai, M., Sugimoto, S., Mori, K., Nanki, K., Ohno, K., Mutaguchi, M., Mizuno, S., Bessho, R., Nakazato, Y., Hosoe, N., Inoue, N., Iwao, Y., Ogata, H. & Kanai, T., 2016 Jan 1, In : Digestion. 93, 1, p. 66-71 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Factors associated with exacerbation of newly diagnosed mild ulcerative colitis based on a nationwide registry in Japan

Kuwahara, E., Murakami, Y., Nakamura, T., Inoue, N., Nagahori, M., Matsui, T., Watanabe, M., Suzuki, Y. & Nishiwaki, Y., 2016 Apr 13, (Accepted/In press) In : Journal of Gastroenterology. p. 1-9 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

The ulcerative colitis endoscopic index of severity is useful to predict medium- to long-term prognosis in ulcerative colitis patients with clinical remission

Arai, M., Naganuma, M., Sugimoto, S., Kiyohara, H., Ono, K., Mori, K., Saigusa, K., Nanki, K., Mutaguchi, M., Mizuno, S., Bessho, R., Nakazato, Y., Hosoe, N., Matsuoka, K., Inoue, N., Ogata, H., Iwao, Y. & Kanai, T., 2016, In : Journal of Crohn's and Colitis. 10, 11, p. 1303-1309 7 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)
2015

Adalimumab for the treatment of japanese patients with intestinal behçet's disease

Tanida, S., Inoue, N., Kobayashi, K., Naganuma, M., Hirai, F., Iizuka, B., Watanabe, K., Mitsuyama, K., Inoue, T., Ishigatsubo, Y., Suzuki, Y., Nagahori, M., Motoya, S., Nakamura, S., Arora, V., Robinson, A. M., Thakkar, R. B. & Hibi, T., 2015 May 1, In : Clinical Gastroenterology and Hepatology. 13, 5, p. 940-948.e3

Research output: Contribution to journalArticle

35 Citations (Scopus)

Risk factors for decreased bone mineral density in inflammatory bowel disease: A cross-sectional study

Wada, Y., Hisamatsu, T., Naganuma, M., Matsuoka, K., Okamoto, S., Inoue, N., Yajima, T., Kouyama, K., Iwao, Y., Ogata, H., Hibi, T., Abe, T. & Kanai, T., 2015 Dec 1, In : Clinical Nutrition. 34, 6, p. 1202-1209 8 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2014

Modified bowel preparation regimen for use in second-generation colon capsule endoscopy in patients with ulcerative colitis

Usui, S., Hosoe, N., Matsuoka, K., Kobayashi, T., Nakano, M., Naganuma, M., Ishibashi, Y., Kimura, K., Yoneno, K., Kashiwagi, K., Hisamatsu, T., Inoue, N., Serizawa, H., Hibi, T., Ogata, H. & Kanai, T., 2014 Sep 1, In : Digestive Endoscopy. 26, 5, p. 665-672 8 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Risk and management of intra-abdominal abscess in crohn's disease treated with infliximab

Yoneno, K., Hisamatsu, T., Matsuoka, K., Okamoto, S., Takayama, T., Ichikawa, R., Sujino, T., Miyoshi, J., Takabayashi, K., Mikami, Y., Mizuno, S., Wada, Y., Yajima, T., Naganuma, M., Inoue, N., Iwao, Y., Ogata, H., Hasegawa, H., Kitagawa, Y., Hibi, T. & 1 others, Kanai, T., 2014 Jun, In : Digestion. 89, 3, p. 201-208 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

The 2nd edition of consensus statements for the diagnosis and management of intestinal Behçet's disease: Indication of anti-TNFα monoclonal antibodies

Hisamatsu, T., Ueno, F., Matsumoto, T., Kobayashi, K., Koganei, K., Kunisaki, R., Hirai, F., Nagahori, M., Matsushita, M., Kobayashi, K., Kishimoto, M., Takeno, M., Tanaka, M., Inoue, N. & Hibi, T., 2014 Jan 1, In : Journal of gastroenterology. 49, 1, p. 156-162 7 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)
2013

Applicability of second-generation colon capsule endoscope to ulcerative colitis: A clinical feasibility study

Hosoe, N., Matsuoka, K., Naganuma, M., Ida, Y., Ishibashi, Y., Kimura, K., Yoneno, K., Usui, S., Kashiwagi, K., Hisamatsu, T., Inoue, N., Kanai, T., Imaeda, H., Ogata, H. & Hibi, T., 2013 Jul, In : Journal of Gastroenterology and Hepatology (Australia). 28, 7, p. 1174-1179 6 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Mucosal healing with oral tacrolimus is associated with favorable medium- and long-term prognosis in steroid-refractory/dependent ulcerative colitis patients

Miyoshi, J., Matsuoka, K., Inoue, N., Hisamatsu, T., Ichikawa, R., Yajima, T., Okamoto, S., Naganuma, M., Sato, T., Kanai, T., Ogata, H., Iwao, Y. & Hibi, T., 2013 Dec 15, In : Journal of Crohn's and Colitis. 7, 12, p. e609-e614

Research output: Contribution to journalArticle

35 Citations (Scopus)

Safety and efficacy of AJG522 as a bowel cleansing agent for colonoscopy in healthy Japanese subjects

Furuie, H., Hirato, H., Yagi, M., Sakurai, T., Yamada, S., Seki, M., Endo, Y., Igarashi, M., Inoue, N. & Ueno, F., 2013 Mar 1, In : Japanese Journal of Clinical Pharmacology and Therapeutics. 44, 2, p. 53-60 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2012

[Colonoscopy in the practice of inflammatory bowel diseases].

Inoue, N. & Iwao, Y., 2012 Feb, In : Nihon rinsho. Japanese journal of clinical medicine. 70 Suppl 1, p. 209-217 9 p.

Research output: Contribution to journalArticle

A case of intestinal Behçet's disease treated with infliximab monotherapy who successfully maintained clinical remission and complete mucosal healing for six years

Maruyama, Y., Hisamatsu, T., Matsuoka, K., Naganuma, M., Inoue, N., Ogata, H., Iwao, Y., Kanai, T. & Hibi, T., 2012 Aug 23, In : Internal Medicine. 51, 16, p. 2125-2129 5 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
8 Citations (Scopus)

Effects of family history on inflammatory bowel disease characteristics in Japanese patients

Kuwahara, E., Asakura, K., Nishiwaki, Y., Inoue, N., Watanabe, M., Hibi, T. & Takebayashi, T., 2012 Sep 1, In : Journal of gastroenterology. 47, 9, p. 961-968 8 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Endoscopic hemostasis for nonvariceal upper gastrointestinal bleeding - Strategies in difficult cases

Imaeda, H., Hosoe, N., Kashiwagi, K., Ohgo, H., Yamaoka, M., Sujino, T., Inoue, N., Suzuki, H., Iwao, Y., Hibi, T. & Ogata, H., 2012 Aug 1, In : GASTROENTEROLOGICAL ENDOSCOPY. 54, 8, p. 2256-2268 13 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Intermittent Granulocyte and Monocyte Apheresis Versus Mercaptopurine for Maintaining Remission of Ulcerative Colitis: A Pilot Study

Sakuraba, A., Sato, T., Morohoshi, Y., Matsuoka, K., Okamoto, S., Inoue, N., Takaishi, H., Ogata, H., Iwao, Y. & Hibi, T., 2012 Jun 1, In : Therapeutic Apheresis and Dialysis. 16, 3, p. 213-218 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Novel, objective, multivariate biomarkers composed of plasma amino acid profiles for the diagnosis and assessment of inflammatory bowel disease

Hisamatsu, T., Okamoto, S., Hashimoto, M., Muramatsu, T., Andou, A., Uo, M., Kitazume, M. T., Matsuoka, K., Yajima, T., Inoue, N., Kanai, T., Ogata, H., Iwao, Y., Yamakado, M., Sakai, R., Ono, N., Ando, T., Suzuki, M. & Hibi, T., 2012 Jan 31, In : PloS one. 7, 1, e31131.

Research output: Contribution to journalArticle

101 Citations (Scopus)
2011

Correlation between endocytoscopy and conventional histopathology in microstructural features of ulcerative colitis.

Bessho, R., Kanai, T., Hosoe, N., Kobayashi, T., Takayama, T., Inoue, N., Mukai, M., Ogata, H. & Hibi, T., 2011, In : Journal of Gastroenterology. 46, 10, p. 1197-1202 6 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Ectopic expression of blood type antigens in inflamed mucosa with higher incidence of FUT2 secretor status in colonic Crohn's disease

Miyoshi, J., Yajima, T., Okamoto, S., Matsuoka, K., Inoue, N., Hisamatsu, T., Shimamura, K., Nakazawa, A., Kanai, T., Ogata, H., Iwao, Y., Mukai, M. & Hibi, T., 2011 Sep 1, In : Journal of gastroenterology. 46, 9, p. 1056-1063 8 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Validity of activity indices in ulcerative colitis: Comparison of clinical and endoscopic indices

Hirai, F., Matsui, T., Aoyagi, K., Inoue, N., Hibi, T., Oshitani, N., Fujii, H., Kobayashi, K., Suzuki, Y. & Tanaka, S., 2011 Dec 1, In : GASTROENTEROLOGICAL ENDOSCOPY. 53, 12, p. 3811-3819 9 p.

Research output: Contribution to journalArticle

2010

Competition between colitogenic Th1 and Th17 cells contributes to the amelioration of colitis

Mikami, Y., Kanai, T., Sujino, T., Ono, Y., Hayashi, A., Okazawa, A., Kamada, N., Matsuoka, K., Hisamatsu, T., Okamoto, S., Takaishi, H., Inoue, N., Ogata, H. & Hibi, T., 2010 Sep, In : European Journal of Immunology. 40, 9, p. 2409-2422 14 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

In vivo visualization of trophozoites in patients with amoebic colitis by using a newly developed endocytoscope

Hosoe, N., Kobayashi, T., Kanai, T., Bessho, R., Takayama, T., Inoue, N., Imaeda, H., Iwao, Y., Kobayashi, S., Mukai, M., Ogata, H. & Hibi, T., 2010 Sep 1, In : Gastrointestinal Endoscopy. 72, 3, p. 643-646 4 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Management of Crohn's disease by immunoreguratoly therapy

Inoue, N. & Ogata, H., 2010 Jun 1, In : Journal of Japanese Society of Gastroenterology. 107, 6, p. 868-875 8 p.

Research output: Contribution to journalArticle

Novel endoscopic activity index is useful for choosing treatment in severe active ulcerative colitis patients

Naganuma, M., Ichikawa, H., Inoue, N., Kobayashi, T., Okamoto, S., Hisamatsu, T., Kanai, T., Ogata, H., Iwao, Y. & Hibi, T., 2010 Sep 1, In : Journal of gastroenterology. 45, 9, p. 936-943 8 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Rapid endoscopic improvement is important for 1-year avoidance of colectomy but not for the long-term prognosis in cyclosporine A treatment for ulcerative colitis

Kobayashi, T., Naganuma, M., Okamoto, S., Hisamatsu, T., Inoue, N., Ichikawa, H., Takayama, T., Saito, R., Sujino, T., Ogata, H., Iwao, Y. & Hibi, T., 2010 Nov 1, In : Journal of gastroenterology. 45, 11, p. 1129-1137 9 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Validity of activity indices in ulcerative colitis: Comparison of clinical and endoscopic indices

Hirai, F., Matsui, T., Aoyagi, K., Inoue, N., Hibi, T., Oshitani, N., Fujii, H., Kobayashi, K., Suzuki, Y. & Tanaka, S., 2010 Jan 1, In : Digestive Endoscopy. 22, 1, p. 39-44 6 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2009

Clinical results of endoscopic hemostasis using a short transparent hood and short hemoclips for non-variceal upper gastrointestinal bleeding: Original article

Hosoe, N., Imaeda, H., Kashiwagi, K., Naganuma, M., Inoue, N., Suzuki, H., Suganuma, K., Ida, Y., Nakamizo, H., Aiura, K., Ogata, H., Iwao, Y., Kumai, K. & Hibi, T., 2009 Apr 1, In : Digestive Endoscopy. 21, 2, p. 93-96 4 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Prediction of survival and complications after percutaneous endoscopic gastrostomy in an individual by using clinical factors with an artificial neural network system

Takayama, T., Takayama, K., Inoue, N., Funakoshi, S., Serizawa, H., Watanabe, N., Kumagai, N., Tsuchimoto, K. & Hibi, T., 2009 Nov 1, In : European Journal of Gastroenterology and Hepatology. 21, 11, p. 1279-1285 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Prevalence of ulcerative colitis and Crohn's disease in Japan

Asakura, K., Nishiwaki, Y., Inoue, N., Hibi, T., Watanabe, M. & Takebayashi, T., 2009 May 8, In : Journal of gastroenterology. 44, 7, p. 659-665 7 p.

Research output: Contribution to journalArticle

156 Citations (Scopus)
2008

A pilot open-labeled prospective randomized study between weekly and intensive treatment of granulocyte and monocyte adsorption apheresis for active ulcerative colitis

Sakuraba, A., Sato, T., Naganuma, M., Morohoshi, Y., Matsuoka, K., Inoue, N., Takaishi, H., Ogata, H., Iwao, Y. & Hibi, T., 2008 Jan 1, In : Journal of gastroenterology. 43, 1, p. 51-56 6 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Exacerbating Role of γδ T Cells in Chronic Colitis of T-Cell Receptor α Mutant Mice

Nanno, M., Kanari, Y., Naito, T., Inoue, N., Hisamatsu, T., Chinen, H., Sugimoto, K., Shimomura, Y., Yamagishi, H., Shiohara, T., Ueha, S., Matsushima, K., Suematsu, M., Mizoguchi, A., Hibi, T., Bhan, A. K. & Ishikawa, H., 2008 Feb, In : Gastroenterology. 134, 2, p. 481-490 10 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Imbalance in intestinal microflora constitution could be involved in the pathogenesis of inflammatory bowel disease

Takaishi, H., Matsuki, T., Nakazawa, A., Takada, T., Kado, S., Asahara, T., Kamada, N., Sakuraba, A., Yajima, T., Higuchi, H., Inoue, N., Ogata, H., Iwao, Y., Nomoto, K., Tanaka, R. & Hibi, T., 2008 Jul 1, In : International Journal of Medical Microbiology. 298, 5-6, p. 463-472 10 p.

Research output: Contribution to journalArticle

183 Citations (Scopus)

Nonpathogenic Escherichia coli strain Nissle 1917 inhibits signal transduction in intestinal epithelial cells

Kamada, N., Maeda, K., Inoue, N., Hisamatsu, T., Okamoto, S., Kyong, S. H., Yamada, T., Watanabe, N., Tsuchimoto, K., Ogata, H. & Hibi, T., 2008 Jan 1, In : Infection and Immunity. 76, 1, p. 214-220 7 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)
2007

Clinical significance of serum p53 antibodies in patients with ulcerative colitis and its carcinogenesis

Yoshizawa, S., Matsuoka, K., Inoue, N., Takaishi, H., Ogata, H., Iwao, Y., Mukai, M., Fujita, T., Kawakami, Y. & Hibi, T., 2007 Jul 1, In : Inflammatory bowel diseases. 13, 7, p. 865-873 9 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Cytomegalovirus is frequently reactivated and disappears without antiviral agents in ulcerative colitis patients

Matsuoka, K., Iwao, Y., Mori, T., Sakuraba, A., Yajima, T., Hisamatsu, T., Okamoto, S., Morohoshi, Y., Izumiya, M., Ichikawa, H., Sato, T., Inoue, N., Ogata, H. & Hibi, T., 2007 Feb 1, In : American Journal of Gastroenterology. 102, 2, p. 331-337 7 p.

Research output: Contribution to journalArticle

146 Citations (Scopus)