• 919 Citations
  • 19 h-Index
20072020

Research output per year

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Research Output

  • 919 Citations
  • 19 h-Index
  • 70 Article
  • 2 Review article
  • 1 Short survey
2020

Appropriate timing for a biochemical evaluation after adrenalectomy for unilateral aldosterone-producing adenoma

Takamatsu, K., Takeda, T., Hattori, S., Tanaka, N., Morita, S., Matsumoto, K., Kosaka, T., Mizuno, R., Shinojima, T., Kikuchi, E., Asanuma, H., Kurihara, I., Itoh, H. & Oya, M., 2020 Jan 1, (Accepted/In press) In : Clinical Endocrinology.

Research output: Contribution to journalArticle

2019

Impact of inflammatory marker levels one month after the first-line targeted therapy initiation on progression-free survival prediction in patients with metastatic clear cell renal cell carcinoma

Ito, K., Masunaga, A., Tanaka, N., Mizuno, R., Shirotake, S., Yasumizu, Y., Ito, Y., Miyazaki, Y., Hagiwara, M., Kanao, K., Mikami, S., Momma, T., Masuda, T., Nakagawa, K., Oyama, M., Asano, T. & Oya, M., 2019 Jan 1, In : Japanese Journal of Clinical Oncology. 49, 1, p. 69-76 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2 Citations (Scopus)

Sub-classification of patients with intermediate-risk metastatic renal cell carcinoma treated with targeted therapy

Kaneko, G., Shirotake, S., Nishimoto, K., Miyazaki, Y., Ito, K., Ito, Y., Hagiwara, M., Kanao, K., Nakagawa, K., Momma, T., Asano, T., Tanaka, N., Mizuno, R., Oya, M. & Oyama, M., 2019 Aug 1, In : Japanese journal of clinical oncology. 49, 8, p. 780-785 6 p.

Research output: Contribution to journalArticle

TNFAIP2 expression induces epithelial-to-mesenchymal transition and confers platinum resistance in urothelial cancer cells

Niwa, N., Tanaka, N., Hongo, H., Miyazaki, Y., Takamatsu, K., Mizuno, R., Kikuchi, E., Mikami, S., Kosaka, T. & Oya, M., 2019 Jan 1, In : Laboratory Investigation.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Type of patients in whom biochemical recurrence after radical prostatectomy can be observed without salvage therapy

Matsumoto, K., Niwa, N., Hagiwara, M., Kosaka, T., Tanaka, N., Takeda, T., Morita, S., Mizuno, R., Shinojima, T., Hara, S., Asanuma, H. & Oya, M., 2019 Jan 1, (Accepted/In press) In : World Journal of Urology.

Research output: Contribution to journalArticle

Volumetric imaging: a potential tool to stage upper tract urothelial carcinoma

Grahn, A., Tanaka, N., Uhlén, P. & Brehmer, M., 2019 Jan 1, In : World Journal of Urology.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2018

BCG-induced cytokine release in bladder cancer cells is regulated by Ca2+ signaling

Ibarra, C., Karlsson, M., Codeluppi, S., Varas-Godoy, M., Zhang, S., Louhivuori, L., Mangsbo, S., Hosseini, A., Soltani, N., Kaba, R., Kalle Lundgren, T., Hosseini, A., Tanaka, N., Oya, M., Wiklund, P., Miyakawa, A. & Uhlén, P., 2018 Jan 1, (Accepted/In press) In : Molecular Oncology.

Research output: Contribution to journalArticle

2 Citations (Scopus)

History of Non–Muscle-Invasive Bladder Cancer May Have a Worse Prognostic Impact in cT2-4aN0M0 Bladder Cancer Patients Treated With Radical Cystectomy

Kayama, E., Kikuchi, E., Fukumoto, K., Shirotake, S., Miyazaki, Y., Hakozaki, K., Kaneko, G., Yoshimine, S., Tanaka, N., Takahiro, M., Kanai, K., Oyama, M., Nakajima, Y., Hara, S., Monma, T. & Oya, M., 2018 Jan 1, (Accepted/In press) In : Clinical Genitourinary Cancer.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Improved Pathological Examination of Tumors with 3D Light-Sheet Microscopy

Uhlén, P. & Tanaka, N., 2018 May 1, In : Trends in Cancer. 4, 5, p. 337-341 5 p.

Research output: Contribution to journalShort survey

2 Citations (Scopus)

Mapping of the three-dimensional lymphatic microvasculature in bladder tumours using light-sheet microscopy

Tanaka, N., Kaczynska, D., Kanatani, S., Sahlgren, C., Mitura, P., Stepulak, A., Miyakawa, A., Wiklund, P. & Uhlén, P., 2018 Apr 1, In : British Journal of Cancer. 118, 7, p. 995-999 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Publisher Correction: Whole-tissue biopsy phenotyping of three-dimensional tumours reveals patterns of cancer heterogeneity

Tanaka, N., Kanatani, S., Tomer, R., Sahlgren, C., Kronqvist, P., Kaczynska, D., Louhivuori, L., Kis, L., Lindh, C., Mitura, P., Stepulak, A., Corvigno, S., Hartman, J., Micke, P., Mezheyeuski, A., Strell, C., Carlson, J. W., Fernández Moro, C., Dahlstrand, H., Östman, A. & 6 others, Matsumoto, K., Wiklund, P., Oya, M., Miyakawa, A., Deisseroth, K. & Uhlén, P., 2018 Jan 2, (Accepted/In press) In : Nature Biomedical Engineering. 1 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Single-cell RNA-seq analysis reveals the platinum resistance gene COX7B and the surrogate marker CD63

Tanaka, N., Katayama, S., Reddy, A., Nishimura, K., Niwa, N., Hongo, H., Ogihara, K., Kosaka, T., Mizuno, R., Kikuchi, E., Mikami, S., Miyakawa, A., Arenas, E., Kere, J., Oya, M. & Uhlén, P., 2018 Jan 1, (Accepted/In press) In : Cancer Medicine.

Research output: Contribution to journalArticle

2 Citations (Scopus)
6 Citations (Scopus)
2017

Prognostic value of neutrophil-to-lymphocyte ratio in patients with metastatic renal cell carcinoma treated with first-line and subsequent second-line targeted therapy: A proposal of the modified-IMDC risk model

Tanaka, N., Mizuno, R., Yasumizu, Y., Ito, K., Shirotake, S., Masunaga, A., Ito, Y., Miyazaki, Y., Hagiwara, M., Kanao, K., Mikami, S., Nakagawa, K., Momma, T., Masuda, T., Asano, T., Oyama, M. & Oya, M., 2017 Feb 1, In : Urologic Oncology: Seminars and Original Investigations. 35, 2, p. 39.e19-39.e28

Research output: Contribution to journalArticle

17 Citations (Scopus)

Significance of a frozen section analysis of the ureteral margin in bladder cancer patients treated with radical cystectomy and neoadjuvant chemotherapy

Hakozaki, K., Kikuchi, E., Fukumoto, K., Shirotake, S., Miyazaki, Y., Maeda, T., Kaneko, G., Yoshimine, S., Tanaka, N., Kanai, K., Oyama, M., Nakajima, Y., Momma, T. & Oya, M., 2017 Dec 1, In : Medical Oncology. 34, 12, 187.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Whole-tissue biopsy phenotyping of three-dimensional tumours reveals patterns of cancer heterogeneity

Tanaka, N., Kanatani, S., Tomer, R., Sahlgren, C., Kronqvist, P., Kaczynska, D., Louhivuori, L., Kis, L., Lindh, C., Mitura, P., Stepulak, A., Corvigno, S., Hartman, J., Micke, P., Mezheyeuski, A., Strell, C., Carlson, J. W., Fernández Moro, C., Dahlstrand, H., Östman, A. & 6 others, Matsumoto, K., Wiklund, P., Oya, M., Miyakawa, A., Deisseroth, K. & Uhlén, P., 2017 Oct 1, In : Nature Biomedical Engineering. 1, 10, p. 796-806 11 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)
2016

Acquired platinum resistance involves epithelial to mesenchymal transition through ubiquitin ligase FBXO32 dysregulation

Tanaka, N., Kosaka, T., Miyazaki, Y., Mikami, S., Niwa, N., Otsuka, Y., Minamishima, Y. A., Mizuno, R., Kikuchi, E., Miyajima, A., Sabe, H., Okada, Y., Uhlén, P., Suematsu, M. & Oya, M., 2016 Jan 1, In : JCI Insight. 1, 18, e83654.

Research output: Contribution to journalArticle

Open Access
14 Citations (Scopus)

External Validation of the MSKCC and IMDC Risk Models in Patients Treated with Targeted Therapy as a First-line and Subsequent Second-line Treatment: A Japanese Multi-institutional Study

Tanaka, N., Mizuno, R., Ito, K., Shirotake, S., Yasumizu, Y., Masunaga, A., Ito, Y., Miyazaki, Y., Hagiwara, M., Kanao, K., Mikami, S., Nakagawa, K., Momma, T., Masuda, T., Asano, T., Oyama, M. & Oya, M., 2016 Aug 1, In : European Urology Focus. 2, 3, p. 303-309 7 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Impact of Second-Line Targeted Therapy Dose Intensity on Patients With Metastatic Renal Cell Carcinoma

Shirotake, S., Yasumizu, Y., Ito, K., Masunaga, A., Ito, Y., Miyazaki, Y., Hagiwara, M., Kanao, K., Mikami, S., Nakagawa, K., Momma, T., Masuda, T., Asano, T., Oyama, M., Tanaka, N., Mizuno, R. & Oya, M., 2016 Jan 30, (Accepted/In press) In : Clinical Genitourinary Cancer.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Patient age was an independent predictor of cancer-specific survival in male patients with upper tract urothelial carcinoma treated by radical nephroureterectomy

Kobayashi, H., Kikuchi, E., Tanaka, N., Shirotake, S., Miyazaki, Y., Ide, H., Obata, J., Hoshino, K., Matsumoto, K., Kaneko, G., Hagiwara, M., Kosaka, T., Oyama, M., Nakajima, Y. & Oya, M., 2016 Jun 1, In : Japanese Journal of Clinical Oncology. 46, 6, p. 554-559 6 p., hyw028.

Research output: Contribution to journalArticle

4 Citations (Scopus)
15 Citations (Scopus)

Relationship Between Increased Expression of the Axl/Gas6 Signal Cascade and Prognosis of Patients with Upper Tract Urothelial Carcinoma

Hattori, S., Kikuchi, E., Kosaka, T., Miyazaki, Y., Tanaka, N., Miyajima, A., Mikami, S. & Oya, M., 2016 Feb 1, In : Annals of Surgical Oncology. 23, 2, p. 663-670 8 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2015

Are the Formulas Used to Estimate Renal Function Adequate for Patients Treated With Cisplatin-Based Chemotherapy After Nephroureterectomy for Upper Tract Urothelial Carcinoma?

Niwa, N., Kikuchi, E., Masashi, M., Tanaka, N., Nishiyama, T., Miyajima, A., Saito, S. & Oya, M., 2015 Dec 27, (Accepted/In press) In : Clinical Genitourinary Cancer.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Comparison of outcomes between ultrasonography and cystoscopy in the surveillance of patients with initially diagnosed TaG1-2 bladder cancers: A matched-pair analysis

Niwa, N., Matsumoto, K., Hayakawa, N., Ito, Y., Maeda, T., Akatsuka, S., Masuda, T., Nakamura, S. & Tanaka, N., 2015 Sep 1, In : Urologic Oncology. 33, 9

Research output: Contribution to journalArticle

7 Citations (Scopus)

Down-regulation of NF kappa B activation is an effective therapeutic modality in acquired platinum-resistant bladder cancer

Ito, Y., Kikuchi, E., Tanaka, N., Kosaka, T., Suzuki, E., Mizuno, R., Shinojima, T., Miyajima, A., Umezawa, K. & Oya, M., 2015 Apr 29, In : BMC Cancer. 15, 1, 324.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Effect of reclassification of the IMDC model in patients with metastatic renal cell carcinoma treated with targeted therapy in the first-line and second-line settings

Tanaka, N., Mizuno, R., Shirotake, S., Ito, K., Yasumizu, Y., Masunaga, A., Ito, Y., Miyazaki, Y., Hagiwara, M., Kanao, K., Mikami, S., Nakagawa, K., Momma, T., Masuda, T., Asano, T., Oyama, M. & Oya, M., 2015 Oct 22, (Accepted/In press) In : Urologic Oncology: Seminars and Original Investigations.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Impact of an adjuvant chemotherapeutic regimen on the clinical outcome in high risk patients with upper tract urothelial carcinoma: A Japanese multi-institution experience

Shirotake, S., Kikuchi, E., Tanaka, N., Matsumoto, K., Miyazaki, Y., Kobayashi, H., Ide, H., Obata, J., Hoshino, K., Kaneko, G., Hagiwara, M., Kosaka, T., Kanao, K., Kodaira, K., Hara, S., Oyama, M., Momma, T., Miyajima, A., Nakagawa, K., Hasegawa, S. & 2 others, Nakajima, Y. & Oya, M., 2015 Apr 1, In : Journal of Urology. 193, 4, p. 1122-1128 7 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Impact of Combined Use of Blood-based Inflammatory Markers on Patients with Upper Tract Urothelial Carcinoma Following Radical Nephroureterectomy: Proposal of a Cumulative Marker Score as a Novel Predictive Tool for Prognosis

Tanaka, N., Kikuchi, E., Kanao, K., Matsumoto, K., Shirotake, S., Miyazaki, Y., Kobayashi, H., Kaneko, G., Hagiwara, M., Ide, H., Obata, J., Hoshino, K., Hayakawa, N., Kosaka, T., Hara, S., Nakagawa, K., Jinzaki, M. & Oya, M., 2015 Aug 1, In : European Urology Focus. 1, 1, p. 54-63 10 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Nicotine induces tumor growth and chemoresistance through activation of the PI3K/Akt/mTOR pathway in bladder cancer

Yuge, K., Kikuchi, E., Hagiwara, M., Yasumizu, Y., Tanaka, N., Kosaka, T., Miyajima, A. & Oya, M., 2015 Sep 1, In : Molecular Cancer Therapeutics. 14, 9, p. 2112-2120 9 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Prognostic Impact of Renin–Angiotensin System Blockade on Renal Cell Carcinoma After Surgery

Miyajima, A., Yazawa, S., Kosaka, T., Tanaka, N., Shirotake, S., Mizuno, R., Kikuchi, E. & Oya, M., 2015 Feb 18, In : Annals of Surgical Oncology. 22, 11, p. 3751-3759 9 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Refraining from Smoking for 15 Years or More Reduced the Risk of Tumor Recurrence in Non-muscle Invasive Bladder Cancer Patients

Ogihara, K., Kikuchi, E., Yuge, K., Ito, Y., Tanaka, N., Matsumoto, K., Miyajima, A., Asakura, H. & Oya, M., 2015 Dec 15, (Accepted/In press) In : Annals of Surgical Oncology. p. 1-8 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2014

A Multi-Institutional Validation of the Prognostic Value of the Neutrophil-to-Lymphocyte Ratio for Upper Tract Urothelial Carcinoma Treated with Radical Nephroureterectomy

Tanaka, N., Kikuchi, E., Kanao, K., Matsumoto, K., Shirotake, S., Miyazaki, Y., Kobayashi, H., Kaneko, G., Hagiwara, M., Ide, H., Obata, J., Hoshino, K., Hayakawa, N., Kosaka, T., Hara, S., Oyama, M., Momma, T., Nakajima, Y., Jinzaki, M. & Oya, M., 2014 Oct 8, In : Annals of Surgical Oncology. 21, 12, p. 4041-4048 8 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

Ductal adenocarcinoma of the prostate forming a mass in the retrovesical space

Niwa, N., Tanaka, N., Horinaga, M., Hayashi, Y., Hisazumi, H. & Masuda, T., 2014 Oct 1, In : Urology. 84, 4, p. e9-e10

Research output: Contribution to journalArticle

Independent predictors for bladder outcomes after treatment of intravesical recurrence following radical nephroureterectomy in patients with primary upper tract urothelial carcinoma

Tanaka, N., Kikuchi, E., Kanao, K., Matsumoto, K., Shirotake, S., Kobayashi, H., Miyazaki, Y., Ide, H., Obata, J., Hoshino, K., Hayakawa, N., Hagiwara, M., Kosaka, T., Oyama, M., Miyajima, A., Momma, T., Nakagawa, K., Jinzaki, M., Hasegawa, S., Nakajima, Y. & 1 others, Oya, M., 2014 Sep, In : Annals of Surgical Oncology. 21, 9, p. 3151-3158 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Long term follow-up in patients with initially diagnosed low grade Ta non-muscle invasive bladder tumors: Tumor recurrence and worsening progression

Kobayashi, H., Kikuchi, E., Mikami, S., Maeda, T., Tanaka, N., Miyajima, A., Nakagawa, K. & Oya, M., 2014 Jan 8, In : BMC Urology. 14, 1, 5.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Metastatic behavior of upper tract urothelial carcinoma after radical nephroureterectomy: Association with primary tumor location

Tanaka, N., Kikuchi, E., Kanao, K., Matsumoto, K., Kobayashi, H., Ide, H., Miyazaki, Y., Obata, J., Hoshino, K., Shirotake, S., Akita, H., Kosaka, T., Miyajima, A., Momma, T., Nakagawa, K., Hasegawa, S., Nakajima, Y., Jinzaki, M. & Oya, M., 2014 Mar 1, In : Annals of Surgical Oncology. 21, 3, p. 1038-1045 8 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Mucosa-associated lymphoid tissue lymphoma arising from the kidney

Niwa, N., Tanaka, N., Horinaga, M., Hongo, H., Ito, Y., Watanabe, T. & Masuda, T., 2014 Feb 27, In : Journal of the Canadian Urological Association. 8, 1-2 FEB, p. E86-E88

Research output: Contribution to journalArticle

3 Citations (Scopus)

Optimal timing of hormonal therapy for prostate-specific antigen recurrence after radical prostatectomy

Matsumoto, K., Mizuno, R., Tanaka, N., Ide, H., Hasegawa, M., Ishida, M., Hayakawa, N., Yasumizu, Y., Hagiwara, M., Hara, S., Kikuchi, E., Miyajima, A., Nakagawa, K., Nakajima, Y., Nakamura, S., Nakashima, J. & Oya, M., 2014 Jul, In : Medical Oncology. 31, 7, 45.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Survival following primary androgen deprivation therapy for localized intermediate- Or high-risk prostate cancer: Comparison with the life expectancy of the age-matched normal population

Matsumoto, K., Hagiwara, M., Tanaka, N., Hayakawa, N., Ishida, M., Ninomiya, A., Nakajima, Y. & Nakamura, S., 2014 Jun, In : Medical Oncology. 31, 6, 979.

Research output: Contribution to journalArticle

6 Citations (Scopus)

The predictive value of C-reactive protein for prognosis in patients with upper tract urothelial carcinoma treated with radical nephroureterectomy: A multi-institutional study

Tanaka, N., Kikuchi, E., Shirotake, S., Kanao, K., Matsumoto, K., Kobayashi, H., Miyazaki, Y., Ide, H., Obata, J., Hoshino, K., Hayakawa, N., Ito, Y., Kosaka, T., Kodaira, K., Oyama, M., Miyajima, A., Momma, T., Nakagawa, K., Ueno, M. & Oya, M., 2014 Jan 1, In : European Urology. 65, 1, p. 227-234 8 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)
12 Citations (Scopus)

Third-line hormonal therapy to treat prostate cancer relapse after initial and second-line hormonal therapy: Report of 52 cases and literature review

Matsumoto, K., Hagiwara, M., Hayakawa, N., Tanaka, N., Ito, Y., Maeda, T., Ninomiya, A., Nagata, H. & Nakamura, S., 2014, In : Asian Pacific Journal of Cancer Prevention. 15, 8, p. 3645-3649 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2013

C-reactive protein: A biomarker of survival in patients with localized upper tract urothelial carcinoma treated with radical nephroureterectomy

Obata, J., Kikuchi, E., Tanaka, N., Matsumoto, K., Hayakawa, N., Ide, H., Miyajima, A., Nakagawa, K. & Oya, M., 2013 Nov 1, In : Urologic Oncology: Seminars and Original Investigations. 31, 8, p. 1725-1730 6 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Efficacy of estramustine phosphate sodium hydrate (EMP) monotherapy in castration-resistant prostate cancer patients: Report of 102 cases and review of literature

Matsumoto, K., Tanaka, N., Hayakawa, N., Ezaki, T., Suzuki, K., Maeda, T., Ninomiya, A. & Nakamura, S., 2013 Dec 1, In : Medical Oncology. 30, 4, 717.

Research output: Contribution to journalReview article

15 Citations (Scopus)

Impact of smoking status on bladder tumor recurrence after radical nephroureterectomy for upper tract urothelial carcinoma

Hagiwara, M., Kikuchi, E., Tanaka, N., Matsumoto, K., Ide, H., Miyajima, A., Masuda, T., Nakamura, S. & Oya, M., 2013 Jun 1, In : Journal of Urology. 189, 6, p. 2062-2068 7 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Patient characteristics and outcomes in metastatic upper tract urothelial carcinoma after radical nephroureterectomy: The experience of Japanese multi-institutions

Tanaka, N., Kikuchi, E., Kanao, K., Matsumoto, K., Kobayashi, H., Miyazaki, Y., Ide, H., Obata, J., Hoshino, K., Shirotake, S., Hayakawa, N., Kosaka, T., Miyajima, A., Momma, T., Nakagawa, K., Hasegawa, S., Nakajima, Y. & Oya, M., 2013 Jul 1, In : BJU international. 112, 2, p. E28-E34

Research output: Contribution to journalArticle

24 Citations (Scopus)

Prognostic value of plasma fibrinogen levels in patients with localized upper tract urothelial carcinoma

Tanaka, N., Kikuchi, E., Matsumoto, K., Hayakawa, N., Ide, H., Miyajima, A., Nakamura, S. & Oya, M., 2013 May 1, In : BJU international. 111, 6, p. 857-864 8 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)