Osamu Nagano

Division of Gene Regulation

Websitehttps://k-ris.keio.ac.jp/html/100002497_ja.html

2880 Citations
24 h-Index

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6 Similar Profiles

Neoplasms Medicine & Life Sciences

Neoplastic Stem Cells Medicine & Life Sciences

Sulfasalazine Medicine & Life Sciences

Hyaluronic Acid Medicine & Life Sciences

Reactive Oxygen Species Medicine & Life Sciences

Stomach Neoplasms Medicine & Life Sciences

Stomach Medicine & Life Sciences

Cisplatin Medicine & Life Sciences

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Research Output 2003 2019

2880 Citations
24 h-Index
52 Article

2 Citations (Scopus)

Glucose transporter 1-mediated vascular translocation of nanomedicines enhances accumulation and efficacy in solid tumors

Suzuki, K., Miura, Y., Mochida, Y., Miyazaki, T., Toh, K., Anraku, Y., Melo, V., Liu, X., Ishii, T., Nagano, O., Saya, H., Cabral, H. & Kataoka, K., 2019 May 10, In : Journal of Controlled Release. 301, p. 28-41 14 p.

Research output: Contribution to journal › Article

Nanomedicine

Facilitative Glucose Transport Proteins

Blood Vessels

Micelles

Neoplasms

Glutaminolysis-related genes determine sensitivity to xCT-targeted therapy in head and neck squamous cell carcinoma

Okazaki, S., Umene, K., Yamasaki, J., Suina, K., Otsuki, Y., Yoshikawa, M., Minami, Y., Masuko, T., Kawaguchi, S., Nakayama, H., Banno, K., Aoki, D., Saya, H. & Nagano, O., 2019 Nov 1, In : Cancer science. 110, 11, p. 3453-3463 11 p.

Research output: Contribution to journal › Article

Open Access

Sulfasalazine

Glutamate Dehydrogenase

Glutamine

Genes

Neoplasms

4 Citations (Scopus)

Development of a functional thyroid model based on an organoid culture system

Saito, Y., Onishi, N., Takami, H., Seishima, R., Inoue, H., Hirata, Y., Kameyama, K., Tsuchihashi, K., Sugihara, E., Uchino, S., Ito, K., Kawakubo, H., Takeuchi, H., Kitagawa, Y., Saya, H. & Nagano, O., 2018 Mar 4, In : Biochemical and Biophysical Research Communications. 497, 2, p. 783-789 7 p.

Research output: Contribution to journal › Article

Organoids

Thyroglobulin

Iodides

Cell culture

Thyroid Gland

1 Citation (Scopus)

Epidermal growth factor receptor promotes glioma progression by regulating xCT and GluN2B-containing N-methyl-d-aspartate–sensitive glutamate receptor signaling

Suina, K., Tsuchihashi, K., Yamasaki, J., Kamenori, S., Shintani, S., Hirata, Y., Okazaki, S., Sampetrean, O., Baba, E., Akashi, K., Mitsuishi, Y., Takahashi, F., Takahashi, K., Saya, H. & Nagano, O., 2018 Jan 1, (Accepted/In press) In : Cancer Science.

Research output: Contribution to journal › Article

Glutamate Receptors

Epidermal Growth Factor Receptor

Glioma

Glutamic Acid

Epidermal Growth Factor

17 Citations (Scopus)

Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival

Shiota, M., Naya, M., Yamamoto, T., Hishiki, T., Tani, T., Takahashi, H., Kubo, A., Koike, D., Itoh, M., Ohmura, M., Kabe, Y., Sugiura, Y., Hiraoka, N., Morikawa, T., Takubo, K., Suina, K., Nagashima, H., Sampetrean, O., Nagano, O., Saya, H. & 3 others, Yamazoe, S., Watanabe, H. & Suematsu, M., 2018 Dec 1, In : Nature Communications. 9, 1, 1561.

Research output: Contribution to journal › Article

Raman Spectrum Analysis

Oxidants

Gold

Raman spectroscopy

tumors