• 126 Citations
  • 7 h-Index
19932017
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Research Output 1993 2017

  • 126 Citations
  • 7 h-Index
  • 22 Article
  • 2 Chapter
  • 1 Editorial
  • 1 Review article
2017

Startup of pedagogy in pharmaceutical education —What to see, how to consider and what is revealed

Arita, E. & Ishikawa, S., 2017, In : Yakugaku Zasshi. 137, 4, p. 393-394 2 p.

Research output: Contribution to journalEditorial

1 Citation (Scopus)

Status and problems of humanities education with respect to pharmacy education

Ishikawa, S., 2017, In : Yakugaku Zasshi. 137, 4, p. 399-405 7 p.

Research output: Contribution to journalReview article

Pharmacy Education
Education
Pharmacists
Curriculum
Communication
2016
2 Citations (Scopus)

Antimutagenic components in Glycyrrhiza against N-methyl-N-nitrosourea in the Ames assay

Inami, K., Mine, Y., Kojo, Y., Tanaka, S., Ishikawa, S. & Mochizuki, M., 2016 Jul 28, (Accepted/In press) In : Natural Product Research. p. 1-5 5 p.

Research output: Contribution to journalArticle

N-methyl-N-nitrosourea
Glycyrrhiza
Methylnitrosourea
Salmonella typhimurium
Salmonella Typhimurium
2014
3 Citations (Scopus)

Antimutagenicity screening of extracts from medicinal and edible plants against N-Methyl-N-nitrosourea by the Ames assay

Tatsuzaki, J., Jinwei, Y., Kojo, Y., Mine, Y., Ishikawa, S., Mochizuki, M. & Inami, K., 2014, In : Genes and Environment. 36, 2, p. 39-46 8 p.

Research output: Contribution to journalArticle

Glycyrrhiza
Ginger
Methylnitrosourea
Edible Plants
mutagenicity
1 Citation (Scopus)

Assessment of the antimutagenic effects of aqueous extracts from herbal medicines against N-Alkyl-N-nitrosoureas-induced mutagenicity using the umu test

Inami, K., Takada, M., Itoh, K., Ishikawa, S. & Mochizuki, M., 2014, In : Genes and Environment. 36, 2, p. 33-38 6 p.

Research output: Contribution to journalArticle

Antimutagenic Agents
Rhizome
Herbal Medicine
mutagenicity
Cinnamomum zeylanicum
2013

Oxidation of n-alkyl-n-(3-carboxypropyl)nitrosamines by iron porphyrin and oxidant forms alkylating mutagens

Inami, K., Yasui, H., Tsugumi, H., Ishikawa, S. & Mochizuki, M., 2013, In : Genes and Environment. 35, 4, p. 99-104 6 p.

Research output: Contribution to journalArticle

butyl(3-carboxypropyl)nitrosamine
Nitrosamines
porphyrin
Porphyrins
Mutagens
2012
2 Citations (Scopus)

Structure and mutagenicity of a direct-acting mutagen derived from the reaction of N-nitroso-N-methylbutylamine with hydroxyl radical

Inami, K., Miura, M., Tsutsumi, N., Okochi, E., Susaki, Y., Ishikawa, S., Motohashi, S., Shiino, J., Takeda, K. & Mochizuki, M., 2012, In : Heterocycles. 84, 2, p. 1081-1088 8 p.

Research output: Contribution to journalArticle

Mutagens
Salmonella typhimurium
Hydroxyl Radical
Oxides
Cytochrome P-450 Enzyme System
2011
9 Citations (Scopus)

7-Azabicyclo[2.2.1]heptane as a structural motif to block mutagenicity of nitrosamines

Ohwada, T., Ishikawa, S., Mine, Y., Inami, K., Yanagimoto, T., Karaki, F., Kabasawa, Y., Otani, Y. & Mochizuki, M., 2011 Apr 15, In : Bioorganic and Medicinal Chemistry. 19, 8, p. 2726-2741 16 p.

Research output: Contribution to journalArticle

Nitrosamines
Hydroxylation
7-azabicyclo(2.2.1)heptane
Dimethylnitrosamine
Heptanes
2010

Interprofessional education at the Keio University Faculty of Pharmacy

Ehara, Y., Abe, Y., Fujimoto, K., Fukushima, N., Iijima, S., Ishikawa, S., Kishimoto, K., Mochizuki, M., Takahashi, K., Yokota, E. & Kobayashi, S., 2010, Advanced Initiatives in Interprofessional Education in Japan: Japan Interprofessional Working and Education Network. Springer Japan, p. 57-63 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Medical Faculties
Students
Medical Students
Education
Learning
2 Citations (Scopus)

Mutagenicity of polyaromatic hydrocarbons by chemical models for cytochrome P450 in Ames assay

Inami, K., Ishikawa, S. & Mochizuki, M., 2010 Jul, In : Toxicological and Environmental Chemistry. 92, 6, p. 1169-1176 8 p.

Research output: Contribution to journalArticle

Chemical Models
mutagenicity
Salmonella typhimurium
Hydrocarbons
Oxidants
2009
9 Citations (Scopus)

Activation Mechanism of N-Nitrosodialkylamines as Environmental Mutagens and Its Application to Antitumor Research

Inami, K., Ishikawa, S., Mochizuki, M. & Ishikawa, S., 2009, In : Genes and Environment. 31, 4, p. 97-104 8 p.

Research output: Contribution to journalArticle

Nitrosamines
Mutagens
Research
Chemical Models
DNA
2007
12 Citations (Scopus)

Ames test-negative carcinogen, ortho-phenyl phenol, binds tubulin and causes aneuploidy in budding yeast

Nunoshiba, T., Watanabe, E., Takahashi, T., Daigaku, Y., Ishikawa, S., Mochizuki, M., Ui, A., Enomoto, T. & Yamamoto, K., 2007 Apr 1, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 617, 1-2, p. 90-97 8 p.

Research output: Contribution to journalArticle

Carcinogenicity Tests
Saccharomycetales
Aneuploidy
Tubulin
Phenol
4 Citations (Scopus)

Cross-linkable Nitrosamines with a Chloroalkyl Group as Candidates for Anticancer Lead Compounds

Ishikawa, S. & Mochizuki, M., 2007, In : Genes and Environment. 29, 1, p. 1-10 10 p.

Research output: Contribution to journalArticle

Nitrosamines
DNA
Acridines
Nitroso Compounds
Alkylation
2006
11 Citations (Scopus)
Deoxyguanosine
Oligonucleotides
Amines
Derivatives
2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline
2005
5 Citations (Scopus)

Apoptosis induced in human cell lines by a butanol extract from Chlorophytum comosum roots

Matsushita, H., Kuwabara, H., Ishikawa, S. & Mochizuki, M., 2005, In : Journal of Health Science. 51, 3, p. 341-345 5 p.

Research output: Contribution to journalArticle

Butanols
U937 Cells
HL-60 Cells
Cells
Apoptosis
2004
7 Citations (Scopus)

Synthesis and properties of bifunctional chloroalkyl nitrosamines with an intercalating moiety

Ishikawa, S., Tajima, M. & Mochizuki, M., 2004 Jul 15, In : Bioorganic and Medicinal Chemistry. 12, 14, p. 3791-3796 6 p.

Research output: Contribution to journalArticle

Nitrosamines
Acridines
Salmonella
DNA
Salmonella typhimurium
2003
22 Citations (Scopus)

A practical approach for the chemical synthesis of 2′-deoxyguanosine-C8 adducts with mutagenic/carcinogenic amino- or nitro-arenes

Takamura-Enya, T., Ishikawa, S., Mochizuki, M. & Wakabayashi, K., 2003 Aug 4, In : Tetrahedron Letters. 44, 32, p. 5969-5973 5 p.

Research output: Contribution to journalArticle

Deoxyguanosine
Cross Reactions
Palladium
4 Citations (Scopus)

Development for an efficient synthesis method of 2'-deoxyguanosine-C8 adducts with several amino/nitro-arenes.

Takamura-Enya, T., Ishikawa, S., Mochizuki, M. & Wakabayashi, K., 2003, Nucleic acids research. Supplement (2001). 3 ed. p. 23-24 2 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Deoxyguanosine
Amines
2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline
DNA Adducts
Meat
7 Citations (Scopus)

Mutagenicity and cross-linking activity of chloroalkylnitrosamines, possible new antitumor lead compounds

Ishikawa, S. & Mochizuki, M., 2003 Jul, In : Mutagenesis. 18, 4, p. 331-335 5 p.

Research output: Contribution to journalArticle

Lead compounds
Nitrosamines
DNA
DNA Repair
Repair
2000
6 Citations (Scopus)

Synthesis and properties of novel bifunctional nitrosamines with ω-chloroalkyl groups

Ishikawa, S., Saitoh, N. & Mochizuki, M., 2000, In : Chemical and Pharmaceutical Bulletin. 48, 10, p. 1500-1503 4 p.

Research output: Contribution to journalArticle

Nitrosamines
Salmonella
Salmonella typhimurium
Lead compounds
DNA
1999
7 Citations (Scopus)

Mutagenicity of potassium alkanediazotates in Chinese hamster V79 cells and their alkylating activity

Ishikawa, S., Seki, M. & Mochizuki, M., 1999, In : Biological and Pharmaceutical Bulletin. 22, 6, p. 577-581 5 p.

Research output: Contribution to journalArticle

Nitroso Compounds
Niacinamide
Cricetulus
Potassium
Isomerism
1998
9 Citations (Scopus)

Mutagenicity of isomeric alkanediazotates, precursors for ultimate alkylating species of carcinogenic N-nitroso compounds

Ishikawa, S., Sawada, A., Kasuya, K. & Mochizuki, M., 1998 Jan 13, In : Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 412, 1, p. 99-107 9 p.

Research output: Contribution to journalArticle

Isomerism
Nitroso Compounds
Potassium
Nitrosamines
pyrazine-2-diazohydroxide
1996
2 Citations (Scopus)

Lack of mutagenicity of diethylstilbestrol metabolite and analog, (±)-indenestrols A and B, in bacterial assays

Ishikawa, S., Oda, T., Sato, Y. & Mochizuki, M., 1996 Jul 5, In : Mutation Research - Genetic Toxicology. 368, 3-4, p. 261-265 5 p.

Research output: Contribution to journalArticle

Diethylstilbestrol
Metabolites
Assays
Estrogen Receptors
indenestrol B
1 Citation (Scopus)

Selective proliferation of human γδ T cells in vitro

Chen, S. H., Oki, A., Ohno, T., Ishikawa, S., Mochizuki, M., Che, Y. F., Dai, H. M. & Ge, X. R., 1996, In : Cell Research. 6, 2, p. 177-187 11 p.

Research output: Contribution to journalArticle

T-Lymphocytes
Interleukin-2
Tissue Donors
Adoptive Immunotherapy
In Vitro Techniques
1993

Nucleotides Bearing a Cleavable Genotoxic Group on the Phosphate

Hayatsu, H., Akashi, M., Inada, N., Takashima, S., Ishikawa, S., Hizatate, S. & Mochizuki, M., 1993 Feb 1, In : Journal of the American Chemical Society. 115, 3, p. 1180-1181 2 p.

Research output: Contribution to journalArticle

Bearings (structural)
Nucleotides
Phosphates

Nucleotides bearing a cleavable genotoxic group on the phosphate.

Hayatsu, H., Ishii, M., Akashi, M., Inada, N., Takashima, S., Ishikawa, S., Hizatate, S. & Mochizuki, M., 1993, In : Nucleic acids symposium series. 29, p. 217-218 2 p.

Research output: Contribution to journalArticle

Nucleotides
Phosphates
Single-Stranded DNA Breaks
Circular DNA
Nitrosamines