• 126 Citations
  • 7 h-Index
19932017
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Research Output 1993 2017

  • 126 Citations
  • 7 h-Index
  • 22 Article
  • 2 Chapter
  • 1 Editorial
  • 1 Review article
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Article
2016
2 Citations (Scopus)

Antimutagenic components in Glycyrrhiza against N-methyl-N-nitrosourea in the Ames assay

Inami, K., Mine, Y., Kojo, Y., Tanaka, S., Ishikawa, S. & Mochizuki, M., 2016 Jul 28, (Accepted/In press) In : Natural Product Research. p. 1-5 5 p.

Research output: Contribution to journalArticle

N-methyl-N-nitrosourea
Glycyrrhiza
Methylnitrosourea
Salmonella typhimurium
Salmonella Typhimurium
2014
3 Citations (Scopus)

Antimutagenicity screening of extracts from medicinal and edible plants against N-Methyl-N-nitrosourea by the Ames assay

Tatsuzaki, J., Jinwei, Y., Kojo, Y., Mine, Y., Ishikawa, S., Mochizuki, M. & Inami, K., 2014, In : Genes and Environment. 36, 2, p. 39-46 8 p.

Research output: Contribution to journalArticle

Glycyrrhiza
Ginger
Methylnitrosourea
Edible Plants
mutagenicity
1 Citation (Scopus)

Assessment of the antimutagenic effects of aqueous extracts from herbal medicines against N-Alkyl-N-nitrosoureas-induced mutagenicity using the umu test

Inami, K., Takada, M., Itoh, K., Ishikawa, S. & Mochizuki, M., 2014, In : Genes and Environment. 36, 2, p. 33-38 6 p.

Research output: Contribution to journalArticle

Antimutagenic Agents
Rhizome
Herbal Medicine
mutagenicity
Cinnamomum zeylanicum
2013

Oxidation of n-alkyl-n-(3-carboxypropyl)nitrosamines by iron porphyrin and oxidant forms alkylating mutagens

Inami, K., Yasui, H., Tsugumi, H., Ishikawa, S. & Mochizuki, M., 2013, In : Genes and Environment. 35, 4, p. 99-104 6 p.

Research output: Contribution to journalArticle

butyl(3-carboxypropyl)nitrosamine
Nitrosamines
porphyrin
Porphyrins
Mutagens
2012
2 Citations (Scopus)

Structure and mutagenicity of a direct-acting mutagen derived from the reaction of N-nitroso-N-methylbutylamine with hydroxyl radical

Inami, K., Miura, M., Tsutsumi, N., Okochi, E., Susaki, Y., Ishikawa, S., Motohashi, S., Shiino, J., Takeda, K. & Mochizuki, M., 2012, In : Heterocycles. 84, 2, p. 1081-1088 8 p.

Research output: Contribution to journalArticle

Mutagens
Salmonella typhimurium
Hydroxyl Radical
Oxides
Cytochrome P-450 Enzyme System
2011
9 Citations (Scopus)

7-Azabicyclo[2.2.1]heptane as a structural motif to block mutagenicity of nitrosamines

Ohwada, T., Ishikawa, S., Mine, Y., Inami, K., Yanagimoto, T., Karaki, F., Kabasawa, Y., Otani, Y. & Mochizuki, M., 2011 Apr 15, In : Bioorganic and Medicinal Chemistry. 19, 8, p. 2726-2741 16 p.

Research output: Contribution to journalArticle

Nitrosamines
Hydroxylation
7-azabicyclo(2.2.1)heptane
Dimethylnitrosamine
Heptanes
2010
2 Citations (Scopus)

Mutagenicity of polyaromatic hydrocarbons by chemical models for cytochrome P450 in Ames assay

Inami, K., Ishikawa, S. & Mochizuki, M., 2010 Jul, In : Toxicological and Environmental Chemistry. 92, 6, p. 1169-1176 8 p.

Research output: Contribution to journalArticle

Chemical Models
mutagenicity
Salmonella typhimurium
Hydrocarbons
Oxidants
2009
9 Citations (Scopus)

Activation Mechanism of N-Nitrosodialkylamines as Environmental Mutagens and Its Application to Antitumor Research

Inami, K., Ishikawa, S., Mochizuki, M. & Ishikawa, S., 2009, In : Genes and Environment. 31, 4, p. 97-104 8 p.

Research output: Contribution to journalArticle

Nitrosamines
Mutagens
Research
Chemical Models
DNA
2007
12 Citations (Scopus)

Ames test-negative carcinogen, ortho-phenyl phenol, binds tubulin and causes aneuploidy in budding yeast

Nunoshiba, T., Watanabe, E., Takahashi, T., Daigaku, Y., Ishikawa, S., Mochizuki, M., Ui, A., Enomoto, T. & Yamamoto, K., 2007 Apr 1, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 617, 1-2, p. 90-97 8 p.

Research output: Contribution to journalArticle

Carcinogenicity Tests
Saccharomycetales
Aneuploidy
Tubulin
Phenol
4 Citations (Scopus)

Cross-linkable Nitrosamines with a Chloroalkyl Group as Candidates for Anticancer Lead Compounds

Ishikawa, S. & Mochizuki, M., 2007, In : Genes and Environment. 29, 1, p. 1-10 10 p.

Research output: Contribution to journalArticle

Nitrosamines
DNA
Acridines
Nitroso Compounds
Alkylation
2006
11 Citations (Scopus)
Deoxyguanosine
Oligonucleotides
Amines
Derivatives
2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline
2005
5 Citations (Scopus)

Apoptosis induced in human cell lines by a butanol extract from Chlorophytum comosum roots

Matsushita, H., Kuwabara, H., Ishikawa, S. & Mochizuki, M., 2005, In : Journal of Health Science. 51, 3, p. 341-345 5 p.

Research output: Contribution to journalArticle

Butanols
U937 Cells
HL-60 Cells
Cells
Apoptosis
2004
7 Citations (Scopus)

Synthesis and properties of bifunctional chloroalkyl nitrosamines with an intercalating moiety

Ishikawa, S., Tajima, M. & Mochizuki, M., 2004 Jul 15, In : Bioorganic and Medicinal Chemistry. 12, 14, p. 3791-3796 6 p.

Research output: Contribution to journalArticle

Nitrosamines
Acridines
Salmonella
DNA
Salmonella typhimurium
2003
22 Citations (Scopus)

A practical approach for the chemical synthesis of 2′-deoxyguanosine-C8 adducts with mutagenic/carcinogenic amino- or nitro-arenes

Takamura-Enya, T., Ishikawa, S., Mochizuki, M. & Wakabayashi, K., 2003 Aug 4, In : Tetrahedron Letters. 44, 32, p. 5969-5973 5 p.

Research output: Contribution to journalArticle

Deoxyguanosine
Cross Reactions
Palladium
7 Citations (Scopus)

Mutagenicity and cross-linking activity of chloroalkylnitrosamines, possible new antitumor lead compounds

Ishikawa, S. & Mochizuki, M., 2003 Jul, In : Mutagenesis. 18, 4, p. 331-335 5 p.

Research output: Contribution to journalArticle

Lead compounds
Nitrosamines
DNA
DNA Repair
Repair
2000
6 Citations (Scopus)

Synthesis and properties of novel bifunctional nitrosamines with ω-chloroalkyl groups

Ishikawa, S., Saitoh, N. & Mochizuki, M., 2000, In : Chemical and Pharmaceutical Bulletin. 48, 10, p. 1500-1503 4 p.

Research output: Contribution to journalArticle

Nitrosamines
Salmonella
Salmonella typhimurium
Lead compounds
DNA
1999
7 Citations (Scopus)

Mutagenicity of potassium alkanediazotates in Chinese hamster V79 cells and their alkylating activity

Ishikawa, S., Seki, M. & Mochizuki, M., 1999, In : Biological and Pharmaceutical Bulletin. 22, 6, p. 577-581 5 p.

Research output: Contribution to journalArticle

Nitroso Compounds
Niacinamide
Cricetulus
Potassium
Isomerism
1998
9 Citations (Scopus)

Mutagenicity of isomeric alkanediazotates, precursors for ultimate alkylating species of carcinogenic N-nitroso compounds

Ishikawa, S., Sawada, A., Kasuya, K. & Mochizuki, M., 1998 Jan 13, In : Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 412, 1, p. 99-107 9 p.

Research output: Contribution to journalArticle

Isomerism
Nitroso Compounds
Potassium
Nitrosamines
pyrazine-2-diazohydroxide
1996
2 Citations (Scopus)

Lack of mutagenicity of diethylstilbestrol metabolite and analog, (±)-indenestrols A and B, in bacterial assays

Ishikawa, S., Oda, T., Sato, Y. & Mochizuki, M., 1996 Jul 5, In : Mutation Research - Genetic Toxicology. 368, 3-4, p. 261-265 5 p.

Research output: Contribution to journalArticle

Diethylstilbestrol
Metabolites
Assays
Estrogen Receptors
indenestrol B
1 Citation (Scopus)

Selective proliferation of human γδ T cells in vitro

Chen, S. H., Oki, A., Ohno, T., Ishikawa, S., Mochizuki, M., Che, Y. F., Dai, H. M. & Ge, X. R., 1996, In : Cell Research. 6, 2, p. 177-187 11 p.

Research output: Contribution to journalArticle

T-Lymphocytes
Interleukin-2
Tissue Donors
Adoptive Immunotherapy
In Vitro Techniques
1993

Nucleotides Bearing a Cleavable Genotoxic Group on the Phosphate

Hayatsu, H., Akashi, M., Inada, N., Takashima, S., Ishikawa, S., Hizatate, S. & Mochizuki, M., 1993 Feb 1, In : Journal of the American Chemical Society. 115, 3, p. 1180-1181 2 p.

Research output: Contribution to journalArticle

Bearings (structural)
Nucleotides
Phosphates

Nucleotides bearing a cleavable genotoxic group on the phosphate.

Hayatsu, H., Ishii, M., Akashi, M., Inada, N., Takashima, S., Ishikawa, S., Hizatate, S. & Mochizuki, M., 1993, In : Nucleic acids symposium series. 29, p. 217-218 2 p.

Research output: Contribution to journalArticle

Nucleotides
Phosphates
Single-Stranded DNA Breaks
Circular DNA
Nitrosamines