• 11128 Citations
  • 31 h-Index
1988 …2019
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Research Output 1988 2019

  • 11128 Citations
  • 31 h-Index
  • 123 Article
  • 3 Review article
  • 1 Conference contribution
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Article
2019

Disseminated histoplasmosis from a calcified lung nodule after long-term corticosteroid therapy in an elderly Japanese patient: A case report

Kobayashi, K., Asakura, T., Kawada, I., Hasegawa, H., Chubachi, S., Ohara, K., Kuramoto, J., Sugiura, H., Fujishima, S., Iwata, S., Umeyama, T., Katano, H., Uwamino, Y., Miyazaki, Y., Kamei, K., Hasegawa, N. & Betsuyaku, T., 2019 Apr 1, In : Medicine. 98, 17, p. e15264

Research output: Contribution to journalArticle

Open Access
Histoplasmosis
Adrenal Cortex Hormones
Lung
Fever
meropenem

Identifying Sepsis Populations Benefitting from Anticoagulant Therapy: A Prospective Cohort Study Incorporating a Restricted Cubic Spline Regression Model

behalf of the Japanese Association for Acute Medicine (JAAM) Focused Outcomes Research in Emergency Care in Acute Respiratory Distress Syndrome, Sepsis Trauma (FORECAST) Study Group, 2019 Jan 1, In : Thrombosis and Haemostasis. 119, 11, p. 1740-1751 12 p.

Research output: Contribution to journalArticle

Disseminated Intravascular Coagulation
Anticoagulants
Sepsis
Cohort Studies
Prospective Studies
1 Citation (Scopus)

Impact of Body Temperature Abnormalities on the Implementation of Sepsis Bundles and Outcomes in Patients With Severe Sepsis: A Retrospective Sub-Analysis of the Focused Outcome Research on Emergency Care for Acute Respiratory Distress Syndrome, Sepsis and Trauma Study

JAAM Focused Outcome Research on Emergency Care for Acute respiratory distress syndrome, Sepsis and Trauma (FORECAST) Group, 2019 May 1, In : Critical care medicine. 47, 5, p. 691-699 9 p.

Research output: Contribution to journalArticle

Adult Respiratory Distress Syndrome
Emergency Medical Services
Body Temperature
Sepsis
Outcome Assessment (Health Care)
2 Citations (Scopus)

In-hospital mortality associated with the misdiagnosis or unidentified site of infection at admission

Abe, T., Tokuda, Y., Shiraishi, A., Fujishima, S., Mayumi, T., Sugiyama, T., Deshpande, G. A., Shiino, Y., Hifumi, T., Otomo, Y., Okamoto, K., Kotani, J., Sakamoto, Y., Sasaki, J., Shiraishi, S. I., Takuma, K., Hagiwara, A., Yamakawa, K., Takeyama, N., Gando, S. & 22 others, Muroya, T., Koike, K., Anan, H., Sugita, M., Miki, Y., Yamashita, H., Kittaka, H., Maehara, J., Nachi, S., Morino, K., Hoshino, A., Yamaguchi, H., Harada, M., Ishikura, H., Kawakami, M., Deguchi, Y., Yoshihara, H., Hanaki, Y., Okada, K., Kaneko, T., Kiyota, K. & Shimizu, Y., 2019 Jun 6, In : Critical Care. 23, 1, 202.

Research output: Contribution to journalArticle

Open Access
Hospital Mortality
Diagnostic Errors
Infection
Propensity Score
Soft Tissue Infections
Hospital Mortality
Intensive Care Units
Sepsis
Japan
Odds Ratio

Prognostic Accuracy of Quick SOFA is different according to the severity of illness in infectious patients

Umemura, Y., Ogura, H., Gando, S., Shiraishi, A., Saitoh, D., Fujishima, S., Mayumi, T., Kushimoto, S., Abe, T., Shiino, Y., Nakada, T. A., Tarui, T., Hifumi, T., Otomo, Y., Okamoto, K., Kotani, J., Sakamoto, Y., Sasaki, J., Shiraishi, S. I., Takuma, K. & 8 others, Tsuruta, R., Hagiwara, A., Masuno, T., Takeyama, N., Yamashita, N., Ikeda, H., Ueyama, M. & Yamakawa, K., 2019 Jan 1, In : Journal of Infection and Chemotherapy.

Research output: Contribution to journalArticle

ROC Curve
Area Under Curve
Hospital Emergency Service
Sepsis
Mortality
1 Citation (Scopus)

Role of disseminated intravascular coagulation in severe sepsis

Japanese Association for Acute Medicine (JAAM) Focused Outcomes Research in Emergency Care in Acute Respiratory Distress Syndrome, Sepsis and Trauma (FORECAST) Study Group, 2019 Jun 1, In : Thrombosis Research. 178, p. 182-188 7 p.

Research output: Contribution to journalArticle

Disseminated Intravascular Coagulation
Sepsis
Multiple Organ Failure
Mortality
Propensity Score
5 Citations (Scopus)

Variations in infection sites and mortality rates among patients in intensive care units with severe sepsis and septic shock in Japan

Abe, T., Ogura, H., Kushimoto, S., Shiraishi, A., Sugiyama, T., Deshpande, G. A., Uchida, M., Nagata, I., Saitoh, D., Fujishima, S., Mayumi, T., Hifumi, T., Shiino, Y., Nakada, T. A., Tarui, T., Otomo, Y., Okamoto, K., Umemura, Y., Kotani, J., Sakamoto, Y. & 13 others, Sasaki, J., Shiraishi, S. I., Takuma, K., Tsuruta, R., Hagiwara, A., Yamakawa, K., Masuno, T., Takeyama, N., Yamashita, N., Ikeda, H., Ueyama, M., Fujimi, S. & Gando, S., 2019 May 3, In : Journal of Intensive Care. 7, 1, 28.

Research output: Contribution to journalArticle

Open Access
Septic Shock
Hospital Mortality
Intensive Care Units
Sepsis
Japan
2018
11 Citations (Scopus)

Characteristics, management, and in-hospital mortality among patients with severe sepsis in intensive care units in Japan: The FORECAST study

Abe, T., Ogura, H., Shiraishi, A., Kushimoto, S., Saitoh, D., Fujishima, S., Mayumi, T., Shiino, Y., Nakada, T. A., Tarui, T., Hifumi, T., Otomo, Y., Okamoto, K., Umemura, Y., Kotani, J., Sakamoto, Y., Sasaki, J., Shiraishi, S. I., Takuma, K., Tsuruta, R. & 43 others, Hagiwara, A., Yamakawa, K., Masuno, T., Takeyama, N., Yamashita, N., Ikeda, H., Ueyama, M., Fujimi, S., Gando, S., Tasaki, O., Mizobata, Y., Funakoshi, H., Okuyama, T., Yamashita, I., Kanai, T., Yamada, Y., Aibiki, M., Sato, K., Yamashita, S., Yoshida, K., Kasaoka, S., Kon, A., Rinka, H., Kato, H., Okudera, H., Narimatsu, E., Fujiwara, T., Sugita, M., Shichinohe, Y., Nakae, H., Iiduka, R., Nakamura, M., Murata, Y., Sato, Y., Ishikura, H., Myojo, Y., Tsujita, Y., Kinoshita, K., Yamaguchi, H., Sakurai, T., Miyatake, S., Saotome, T. & Yasuda, S., 2018 Nov 22, In : Critical Care. 22, 1, 322.

Research output: Contribution to journalArticle

Open Access
Adult Respiratory Distress Syndrome
Emergency Medical Services
Hospital Mortality
Intensive Care Units
Sepsis
1 Citation (Scopus)

Complementary Role of Hypothermia Identification to the Quick Sequential Organ Failure Assessment Score in Predicting Patients With Sepsis at High Risk of Mortality: A Retrospective Analysis From a Multicenter, Observational Study

Kushimoto, S., Gando, S., Ogura, H., Umemura, Y., Saitoh, D., Mayumi, T., Fujishima, S., Abe, T., Shiraishi, A., Ikeda, H., Kotani, J., Miki, Y., Shiraishi, S. I., Suzuki, K., Suzuki, Y., Takeyama, N., Takuma, K., Tsuruta, R., Yamaguchi, Y., Yamashita, N. & 1 others, Aikawa, N., 2018 Jan 1, (Accepted/In press) In : Journal of Intensive Care Medicine.

Research output: Contribution to journalArticle

Organ Dysfunction Scores
Hypothermia
Multicenter Studies
Observational Studies
Sepsis
6 Citations (Scopus)

Plasma sE-cadherin and the plasma sE-cadherin/sVE-cadherin ratio are potential biomarkers for chronic obstructive pulmonary disease

Shirahata, T., Nakamura, H., Nakajima, T., Nakamura, M., Chubachi, S., Yoshida, S., Tsuduki, K., Mashimo, S., Takahashi, S., Minematsu, N., Tateno, H., Asano, K., Fujishima, S. & Betsuyaku, T., 2018 Feb 12, (Accepted/In press) In : Biomarkers. p. 1-8 8 p.

Research output: Contribution to journalArticle

Pulmonary diseases
Biomarkers
Cadherins
Chronic Obstructive Pulmonary Disease
Plasmas
16 Citations (Scopus)

The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J-SSCG 2016)

Nishida, O., Ogura, H., Egi, M., Fujishima, S., Hayashi, Y., Iba, T., Imaizumi, H., Inoue, S., Kakihana, Y., Kotani, J., Kushimoto, S., Masuda, Y., Matsuda, N., Matsushima, A., Nakada, T. A., Nakagawa, S., Nunomiya, S., Sadahiro, T., Shime, N., Yatabe, T. & 53 others, Hara, Y., Hayashida, K., Kondo, Y., Sumi, Y., Yasuda, H., Aoyama, K., Azuhata, T., Doi, K., Doi, M., Fujimura, N., Fuke, R., Fukuda, T., Goto, K., Hasegawa, R., Hashimoto, S., Hatakeyama, J., Hayakawa, M., Hifumi, T., Higashibeppu, N., Hirai, K., Hirose, T., Ide, K., Kaizuka, Y., Kan'o, T., Kawasaki, T., Kuroda, H., Matsuda, A., Matsumoto, S., Nagae, M., Onodera, M., Ohnuma, T., Oshima, K., Saito, N., Sakamoto, S., Sakuraya, M., Sasano, M., Sato, N., Sawamura, A., Shimizu, K., Shirai, K., Takei, T., Takeuchi, M., Takimoto, K., Taniguchi, T., Tatsumi, H., Tsuruta, R., Yama, N., Yamakawa, K., Yamashita, C., Yamashita, K., Yoshida, T., Tanaka, H. & Oda, S., 2018 Feb 2, In : Journal of Intensive Care. 6, 1, 7.

Research output: Contribution to journalArticle

Practice Management
Septic Shock
Practice Guidelines
Sepsis
Medicine
2017
8 Citations (Scopus)

Assessment of mortality by qSOFA in patients with sepsis outside ICU: A post hoc subgroup analysis by the Japanese Association for Acute Medicine Sepsis Registry Study Group

Umemura, Y., Ogura, H., Gando, S., Kushimoto, S., Saitoh, D., Mayumi, T., Fujishima, S., Abe, T., Ikeda, H., Kotani, J., Miki, Y., Shiraishi, S. I., Shiraishi, A., Suzuki, K., Suzuki, Y., Takeyama, N., Takuma, K., Tsuruta, R., Yamaguchi, Y., Yamashita, N. & 1 others, Aikawa, N., 2017, (Accepted/In press) In : Journal of Infection and Chemotherapy.

Research output: Contribution to journalArticle

Intensive Care Units
Registries
Sepsis
Medicine
Organ Dysfunction Scores
1307 Citations (Scopus)

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016

Rhodes, A., Evans, L. E., Alhazzani, W., Levy, M. M., Antonelli, M., Ferrer, R., Kumar, A., Sevransky, J. E., Sprung, C. L., Nunnally, M. E., Rochwerg, B., Rubenfeld, G. D., Angus, D. C., Annane, D., Beale, R. J., Bellinghan, G. J., Bernard, G. R., Chiche, J. D., Coopersmith, C., De Backer, D. P. & 39 others, French, C. J., Fujishima, S., Gerlach, H., Hidalgo, J. L., Hollenberg, S. M., Jones, A. E., Karnad, D. R., Kleinpell, R. M., Koh, Y., Lisboa, T. C., Machado, F. R., Marini, J. J., Marshall, J. C., Mazuski, J. E., McIntyre, L. A., McLean, A. S., Mehta, S., Moreno, R. P., Myburgh, J., Navalesi, P., Nishida, O., Osborn, T. M., Perner, A., Plunkett, C. M., Ranieri, M., Schorr, C. A., Seckel, M. A., Seymour, C. W., Shieh, L., Shukri, K. A., Simpson, S. Q., Singer, M., Thompson, B. T., Townsend, S. R., Van der Poll, T., Vincent, J. L., Wiersinga, W. J., Zimmerman, J. L. & Dellinger, R. P., 2017 Mar 1, In : Intensive Care Medicine. 43, 3, p. 304-377 74 p.

Research output: Contribution to journalArticle

Septic Shock
Sepsis
Guidelines
Practice Guidelines
Committee Membership
2016

Erratum: Distinct effects of endogenous interleukin-23 on eosinophilic airway inflammation in response to different antigens (Allergology International (2015) 64 (S24-S29))

Ogawa, R., Suzuki, Y., Kagawa, S., Masaki, K., Fukunaga, K., Yoshimura, A., Fujishima, S., Terashima, T., Betsuyaku, T. & Asano, K., 2016 Jan 1, In : Allergology International. 65, 1, p. 120 1 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Infection site is predictive of outcome in acute lung injury associated with severe sepsis and septic shock

Japanese Association for Acute Medicine Sepsis Registry (JAAM SR) Study Group, 2016 Jul 1, In : Respirology. 21, 5, p. 898-904 7 p.

Research output: Contribution to journalArticle

Acute Lung Injury
Septic Shock
Sepsis
Infection
Mortality
9 Citations (Scopus)

Plasma Cathepsin S and Cathepsin S/Cystatin C Ratios Are Potential Biomarkers for COPD

Nakajima, T., Nakamura, H., Owen, C. A., Yoshida, S., Tsuduki, K., Chubachi, S., Shirahata, T., Mashimo, S., Nakamura, M., Takahashi, S., Minematsu, N., Tateno, H., Fujishima, S., Asano, K., Celli, B. R. & Betsuyaku, T., 2016, In : Disease Markers. 2016, 4093870.

Research output: Contribution to journalArticle

cathepsin S
Cystatin C
Biomarkers
Chronic Obstructive Pulmonary Disease
Plasmas
6 Citations (Scopus)

Prognostic factors of Streptococcus pneumoniae infection in adults

Hifumi, T., Fujishima, S., Abe, T., Kiriu, N., Inoue, J., Kato, H., Koido, Y., Kawakita, K., Kuroda, Y., Sasaki, J. & Hori, S., 2016 Feb 1, In : American Journal of Emergency Medicine. 34, 2, p. 202-206 5 p.

Research output: Contribution to journalArticle

Pneumococcal Infections
Sepsis
Pneumonia
Organ Dysfunction Scores
Mortality
2015
2 Citations (Scopus)

Distinct effects of endogenous interleukin-23 on eosinophilic airway inflammation in response to different antigens

Ogawa, R., Suzuki, Y., Kagawa, S., Masaki, K., Fukunaga, K., Yoshimura, A., Fujishima, S., Terashima, T., Betsuyaku, T. & Asano, K., 2015 Jan 4, (Accepted/In press) In : Allergology International.

Research output: Contribution to journalArticle

Interleukin-23
Pyroglyphidae
Inflammation
Antigens
Interleukins
2014
19 Citations (Scopus)

A multicenter, prospective evaluation of quality of care and mortality in japan based on the surviving sepsis campaign guidelines

Fujishima, S., Gando, S., Saitoh, D., Mayumi, T., Kushimoto, S., Shiraishi, S. I., Ogura, H., Takuma, K., Kotani, J., Ikeda, H., Yamashita, N., Suzuki, K., Tsuruta, R., Takeyama, N., Araki, T., Suzuki, Y., Miki, Y., Yamaguchi, Y. & Aikawa, N., 2014, In : Journal of Infection and Chemotherapy. 20, 2, p. 115-120 6 p.

Research output: Contribution to journalArticle

Quality of Health Care
Sepsis
Japan
Guidelines
Mortality
42 Citations (Scopus)

Epidemiology of severe sepsis in Japanese intensive care units: A prospective multicenter study

Ogura, H., Gando, S., Saitoh, D., Takeyama, N., Kushimoto, S., Fujishima, S., Mayumi, T., Araki, T., Ikeda, H., Kotani, J., Miki, Y., Shiraishi, S. I., Suzuki, K., Suzuki, Y., Takuma, K., Tsuruta, R., Yamaguchi, Y., Yamashita, N. & Aikawa, N., 2014, In : Journal of Infection and Chemotherapy. 20, 3, p. 157-162 6 p.

Research output: Contribution to journalArticle

Disseminated Intravascular Coagulation
Multicenter Studies
Intensive Care Units
Sepsis
Epidemiology
1 Citation (Scopus)

Pharmacokinetics of a polyene antifungal agent, liposomal amphotericin B (L-AMB), in a severely burned patient

Sasaki, J., Matsumoto, K., Fujishima, S., Morita, K. & Hori, S., 2014 Oct 1, In : Journal of Chemotherapy. 26, 5, p. 312-314 3 p.

Research output: Contribution to journalArticle

Polyenes
Injury Severity Score
Fatal Outcome
Antifungal Agents
Microbial Sensitivity Tests
6 Citations (Scopus)

Plasma cytokine profiles related to smoking-sensitivity and phenotypes of chronic obstructive pulmonary disease

Nakamura, M., Nakamura, H., Minematsu, N., Chubachi, S., Miyazaki, M., Yoshida, S., Tsuduki, K., Shirahata, T., Mashimo, S., Takahashi, S., Nakajima, T., Tateno, H., Fujishima, S. & Betsuyaku, T., 2014, In : Biomarkers. 19, 5, p. 368-377 10 p.

Research output: Contribution to journalArticle

Pulmonary diseases
Chronic Obstructive Pulmonary Disease
Smoking
Cytokines
Phenotype
4 Citations (Scopus)

Rho-kinase contributes to pressure-induced constriction of renal microvessels

Honma, K., Hayashi, K., Wakino, S., Tokuyama, H., Kanda, T., Tatematsu, S., Hasegawa, K., Fujishima, S., Hori, S., Saruta, T. & Itoh, H., 2014, In : Keio Journal of Medicine. 63, 1, p. 1-12 12 p.

Research output: Contribution to journalArticle

rho-Associated Kinases
Arterioles
Microvessels
Constriction
Kidney
2013
65 Citations (Scopus)

A multicenter, prospective validation study of the Japanese association for acute medicine disseminated intravascular coagulation scoring system in patients with severe sepsis

Gando, S., Saitoh, D., Ogura, H., Fujishima, S., Mayumi, T., Araki, T., Ikeda, H., Kotani, J., Kushimoto, S., Miki, Y., Shiraishi, S. I., Suzuki, K., Suzuki, Y., Takeyama, N., Takuma, K., Tsuruta, R., Yamaguchi, Y., Yamashita, N. & Aikawa, N., 2013 Jun 20, In : Critical Care. 17, 3, R111.

Research output: Contribution to journalArticle

Disseminated Intravascular Coagulation
Validation Studies
Sepsis
Medicine
Prospective Studies
1 Citation (Scopus)

Fatal overwhelming postsplenectomy infection caused by Streptococcus pneumoniae in mothers within 1 year after delivery: Case report

Hifumi, T., Fujishima, S., Chang, B., Sasaki, J., Kiriu, N., Kato, H., Inoue, J. & Koido, Y., 2013 Dec, In : Journal of Infection and Chemotherapy. 19, 6, p. 1202-1205 4 p.

Research output: Contribution to journalArticle

Pneumococcal Infections
Splenectomy
Mothers
Vaccination
Pregnant Women

Neuroleptic malignant syndrome-induced massive coagulopathy treated by recombinant human soluble thrombomodulin.

Hayashida, K., Fujishima, S., Nakaya, N., Abe, S., Shiroshita-Takeshita, A. & Hori, S., 2013 Mar, In : The American journal of emergency medicine. 31, 3

Research output: Contribution to journalArticle

Methotrimeprazine
Neuroleptic Malignant Syndrome
Thrombomodulin
Disseminated Intravascular Coagulation
Recombinant Proteins

Pharmacological therapies for ARDS

Izumida, H. & Fujishima, S., 2013 May, In : Japanese Journal of Anesthesiology. 62, 5, p. 541-546 6 p.

Research output: Contribution to journalArticle

Adult Respiratory Distress Syndrome
Pharmacology
Adrenal Cortex Hormones
Methylprednisolone
Therapeutics
8 Citations (Scopus)

Renal microcirculation and calcium channel subtypes

Honma, K., Hayashi, K., Yamaguchi, S., Fujishima, S., Hori, S. & Itoh, H., 2013, In : Current Hypertension Reviews. 9, 3, p. 182-186 5 p.

Research output: Contribution to journalArticle

Calcium Channels
Microcirculation
Kidney
Arterioles
Mibefradil
HDL Lipoproteins
Chronic Renal Insufficiency
Renal Dialysis
LDL Lipoproteins
Maintenance
7 Citations (Scopus)
HDL Lipoproteins
Chronic Renal Insufficiency
Renal Dialysis
LDL Lipoproteins
Maintenance
2624 Citations (Scopus)

Surviving sepsis campaign: International guidelines for management of severe sepsis and septic shock, 2012

The Surviving Sepsis Campaign Guidelines Committee including The Pediatric Subgroup, 2013, In : Intensive Care Medicine. 39, 2, p. 165-228 64 p.

Research output: Contribution to journalArticle

Septic Shock
Sepsis
Guidelines
Adult Respiratory Distress Syndrome
Positive-Pressure Respiration
3690 Citations (Scopus)

Surviving sepsis campaign: International guidelines for management of severe sepsis and septic shock: 2012

The Surviving Sepsis Campaign Guidelines Committee including The Pediatric Subgroup, 2013, In : Critical Care Medicine. 41, 2, p. 580-637 58 p.

Research output: Contribution to journalArticle

Septic Shock
Sepsis
Guidelines
Adult Respiratory Distress Syndrome
Positive-Pressure Respiration
59 Citations (Scopus)

The impact of body temperature abnormalities on the disease severity and outcome in patients with severe sepsis: An analysis from a multicenter, prospective survey of severe sepsis

Kushimoto, S., Gando, S., Saitoh, D., Mayumi, T., Ogura, H., Fujishima, S., Araki, T., Ikeda, H., Kotani, J., Miki, Y., Shiraishi, S. I., Suzuki, K., Suzuki, Y., Takeyama, N., Takuma, K., Tsuruta, R., Yamaguchi, Y., Yamashita, N. & Aikawa, N., 2013 Nov 13, In : Critical Care. 17, 6, R271.

Research output: Contribution to journalArticle

Body Temperature
Sepsis
Hypothermia
Mortality
APACHE
2012
5 Citations (Scopus)

Clinical efficacy and safety of intravenous itraconazole in the management of invasive candidiasis in patients ofsurgery and critical care

Takesue, Y., Oda, S., Fujishima, S., Mikamo, H. & Aikawa, N., 2012 Aug, In : Journal of Infection and Chemotherapy. 18, 4, p. 515-521 7 p.

Research output: Contribution to journalArticle

Invasive Candidiasis
Itraconazole
Critical Care
Patient Care
Safety
1 Citation (Scopus)
Disaster Medicine
Disaster Planning
Emergency Medical Technicians
Earthquakes
Disasters
2011
28 Citations (Scopus)

Carbon black nanoparticles enhance bleomycin-induced lung inflammatory and fibrotic changes in mice

Kamata, H., Tasaka, S., Inoue, K. I., Miyamoto, K., Nakano, Y., Shinoda, H., Kimizuka, Y., Fujiwara, H., Ishii, M., Hasegawa, N., Takamiya, R., Fujishima, S., Takano, H. & Ishizaka, A., 2011 Mar, In : Experimental Biology and Medicine. 236, 3, p. 315-324 10 p.

Research output: Contribution to journalArticle

Soot
Bleomycin
Nanoparticles
Lung
Bronchoalveolar Lavage Fluid
8 Citations (Scopus)

Early administration of sivelestat, the neutrophil elastase inhibitor, in adults for acute lung injury following gastric aspiration

Hayashida, K., Fujishima, S., Sasao, K., Orita, T., Toyoda, Y., Kitano, M. & Hori, S., 2011 Sep, In : Shock. 36, 3, p. 223-227 5 p.

Research output: Contribution to journalArticle

Secretory Proteinase Inhibitory Proteins
Acute Lung Injury
Stomach
Lung Injury
Confidence Intervals
2010
51 Citations (Scopus)

Clinical aspects of invasive infections with Streptococcus dysgalactiae ssp. equisimilis in Japan: Differences with respect to Streptococcus pyogenes and Streptococcus agalactiae infections

Takahashi, T., Sunaoshi, K., Sunakawa, K., Fujishima, S., Watanabe, H. & Ubukata, K., 2010, In : Clinical Microbiology and Infection. 16, 8, p. 1097-1103 7 p.

Research output: Contribution to journalArticle

Streptococcus agalactiae
Streptococcus pyogenes
Streptococcus
Japan
Infection
4 Citations (Scopus)

Involvement of E-cadherin cleavage in reperfusion injury

Goto, T., Ishizaka, A., Katayama, M., Kohno, M., Tasaka, S., Fujishima, S., Kobayashi, K. & Nomori, H., 2010 Feb, In : European Journal of Cardio-thoracic Surgery. 37, 2, p. 426-431 6 p.

Research output: Contribution to journalArticle

Cadherins
Reperfusion Injury
Bronchoalveolar Lavage Fluid
Lung
Albumins
17 Citations (Scopus)

Laminin γ2 fragments are increased in the circulation of patients with early phase acute lung injury

Katayama, M., Ishizaka, A., Sakamoto, M., Fujishima, S., Sekiguchi, K., Asano, K., Betsuyaku, T., Kotani, T., Ware, L. B., Matthay, M. A. & Hashimoto, S., 2010 Mar, In : Intensive Care Medicine. 36, 3, p. 479-486 8 p.

Research output: Contribution to journalArticle

Acute Lung Injury
Laminin
Pulmonary Edema
Epithelium
Re-Epithelialization
44 Citations (Scopus)

Production and activation of matrix metalloproteinase 7 (matrilysin 1) in the lungs of patients with idiopathic pulmonary fibrosis

Fujishima, S., Shiomi, T., Yamashita, S., Yogo, Y., Nakano, Y., Inoue, T., Nakamura, M., Tasaka, S., Hasegawa, N., Aikawa, N., Ishizaka, A. & Okada, Y., 2010 Aug, In : Archives of Pathology and Laboratory Medicine. 134, 8, p. 1136-1142 7 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 7
Idiopathic Pulmonary Fibrosis
Lung
Epithelial Cells
Interstitial Lung Diseases
2009
21 Citations (Scopus)

Effects of tnf-α-converting enzyme inhibition on acute lung injury induced by endotoxin in the rat

Shimizu, M., Hasegawa, N., Nishimura, T., Endo, Y., Shiraishi, Y., Yamasawa, W., Koh, H., Tasaka, S., Shimada, H., Nakano, Y., Fujishima, S., Yamaguchi, K. & Ishizaka, A., 2009 Nov, In : Shock. 32, 5, p. 535-540 6 p.

Research output: Contribution to journalArticle

Acute Lung Injury
Endotoxins
Bronchoalveolar Lavage Fluid
Enzymes
Neutrophils
45 Citations (Scopus)

Elevated CC chemokine level in bronchoalveolar lavage fluid is predictive of a poor outcome of idiopathic pulmonary fibrosis

Shinoda, H., Tasaka, S., Fujishima, S., Yamasawa, W., Miyamoto, K., Nakano, Y., Kamata, H., Hasegawa, N. & Ishizaka, A., 2009, In : Respiration. 78, 3, p. 285-292 8 p.

Research output: Contribution to journalArticle

CC Chemokines
Idiopathic Pulmonary Fibrosis
Bronchoalveolar Lavage Fluid
Chemokine CCL22
Chemokine CCL17
19 Citations (Scopus)

Intratracheal synthetic CpG oligodeoxynucleotide causes acute lung injury with systemic inflammatory response

Tasaka, S., Kamata, H., Miyamoto, K., Nakano, Y., Shinoda, H., Kimizuka, Y., Fujiwara, H., Hasegawa, N., Fujishima, S., Miyasho, T. & Ishizaka, A., 2009 Sep 23, In : Respiratory Research. 10, 84.

Research output: Contribution to journalArticle

Acute Lung Injury
Oligodeoxyribonucleotides
Cytosine
Guanine
Phosphates
9 Citations (Scopus)

In vivo il-18 supplementation ameliorates lethal acute lung injury in burn-primed endotoxemic mice: A novel anti-inflammatory role of IL-18

Sekine, K., Fujishima, S., Sasaki, J., Ishizaka, A., Aiso, S. & Aikawa, N., 2009 Nov, In : Shock. 32, 5, p. 554-562 9 p.

Research output: Contribution to journalArticle

Interleukin-18
Acute Lung Injury
Burns
Anti-Inflammatory Agents
Interleukin-10
42 Citations (Scopus)

Macrophage derived chemokine (CCL22), thymus and activation-regulated chemokine (CCL17), and CCR4 in idiopathic pulmonary fibrosis

Yogo, Y., Fujishima, S., Inoue, T., Saito, F., Shiomi, T., Yamaguchi, K. & Ishizaka, A., 2009 Aug 29, In : Respiratory Research. 10, 80.

Research output: Contribution to journalArticle

Chemokine CCL22
Chemokine CCL17
Idiopathic Pulmonary Fibrosis
Alveolar Macrophages
Pulmonary Fibrosis
2008
26 Citations (Scopus)

Neutrophil elastase and systemic inflammatory response syndrome in the initiation and development of acute lung injury among critically ill patients

Fujishima, S., Morisaki, H., Ishizaka, A., Kotake, Y., Miyaki, M., Yoh, K., Sekine, K., Sasaki, J., Tasaka, S., Hasegawa, N., Kawai, Y., Takeda, J. & Aikawa, N., 2008 Jun, In : Biomedicine and Pharmacotherapy. 62, 5, p. 333-338 6 p.

Research output: Contribution to journalArticle

Systemic Inflammatory Response Syndrome
Leukocyte Elastase
Acute Lung Injury
Critical Illness
Adult Respiratory Distress Syndrome
107 Citations (Scopus)

Role of interleukin-6 in bleomycin-induced lung inflammatory changes in mice

Saito, F., Tasaka, S., Inoue, K. I., Miyamoto, K., Nakano, Y., Ogawa, Y., Yamasawa, W., Shiraishi, Y., Hasegawa, N., Fujishima, S., Takano, H. & Ishizaka, A., 2008 May 1, In : American Journal of Respiratory Cell and Molecular Biology. 38, 5, p. 566-571 6 p.

Research output: Contribution to journalArticle

Bleomycin
Interleukin-6
Lung
Bronchoalveolar Lavage Fluid
Lung Injury
49 Citations (Scopus)

Usefulness of procalcitonin serum level for the discrimination of severe sepsis from sepsis: A multicenter prospective study

Endo, S., Aikawa, N., Fujishima, S., Sekine, I., Kogawa, K., Yamamoto, Y., Kushimoto, S., Yukioka, H., Kato, N., Totsuka, K., Kikuchi, K., Ikeda, T., Ikeda, K., Yamada, H., Harada, K. & Satomura, S., 2008 Jun, In : Journal of Infection and Chemotherapy. 14, 3, p. 244-249 6 p.

Research output: Contribution to journalArticle

Calcitonin
Multicenter Studies
Sepsis
Prospective Studies
Serum