• 628 Citations
  • 12 h-Index
19992015
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Research Output 1999 2015

  • 628 Citations
  • 12 h-Index
  • 20 Article
  • 1 Chapter
2015
4 Citations (Scopus)

Ampullary adenoma treated by endoscopic double-snare retracting papillectomy

Soma, H., Miyata, N., Hozawa, S., Higuchi, H., Yamagishi, Y., Nakamura, Y., Saeki, K., Kameyama, K., Masugi, Y., Yahagi, N. & Kanai, T., 2015 Sep 1, In : Gut and Liver. 9, 5, p. 689-692 4 p.

Research output: Contribution to journalArticle

Adenoma
Ampulla of Vater
Duodenitis
Polyps
Surgical Instruments
2013
4 Citations (Scopus)

Biliary Findings Assist in Predicting Enlargement of Intraductal Papillary Mucinous Neoplasms of the Pancreas

Matsuzaki, J., Suzuki, H., Okuda, S., Tanimoto, A., Asakura, K., Fukuhara, S., Okada, S., Hirata, K., Mori, H., Masaoka, T., Higuchi, H., Hozawa, S., Kuribayashi, S., Takebayashi, T. & Hibi, T., 2013 May, In : Clinical Gastroenterology and Hepatology. 11, 5, p. 548-554 7 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Magnetic Resonance Cholangiopancreatography
Gallbladder
Common Bile Duct
Confidence Intervals
7 Citations (Scopus)

CCR2 knockout exacerbates cerulein-induced chronic pancreatitis with hyperglycemia via decreased GLP-1 receptor expression and insulin secretion

Nakamura, Y., Kanai, T., Saeki, K., Takabe, M., Irie, J., Miyoshi, J., Mikami, Y., Teratani, T., Suzuki, T., Miyata, N., Hisamatsu, T., Nakamoto, N., Yamagishi, Y., Higuchi, H., Ebinuma, H., Hozawa, S., Saito, H., Itoh, H. & Hibi, T., 2013, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 304, 8

Research output: Contribution to journalArticle

Ceruletide
Peptide Receptors
Chronic Pancreatitis
Hyperglycemia
Insulin
2012
43 Citations (Scopus)

CCL2-induced migration and SOCS3-mediated activation of macrophages are involved in cerulein-induced pancreatitis in mice

Saeki, K., Kanai, T., Nakano, M., Nakamura, Y., Miyata, N., Sujino, T., Yamagishi, Y., Ebinuma, H., Takaishi, H., Ono, Y., Takeda, K., Hozawa, S., Yoshimura, A. & Hibi, T., 2012 Apr, In : Gastroenterology. 142, 4

Research output: Contribution to journalArticle

Ceruletide
Macrophage Activation
Pancreatitis
Macrophages
Parabiosis

Hemobilia due to biliary intraepithelial neoplasia associated with Zollinger-Ellison syndrome

Umeda, R., Nakamura, Y., Masugi, Y., Shinoda, M., Hosoe, N., Ono, Y., Fujimura, T., Yamagishi, Y., Higuchi, H., Ebinuma, H., Hozawa, S., Tanabe, M., Hashimoto, S., Sakamoto, M., Kitagawa, Y. & Hibi, T., 2012 Jun, In : Clinical Journal of Gastroenterology. 5, 3, p. 189-194 6 p.

Research output: Contribution to journalArticle

Hemobilia
Gastrinoma
Zollinger-Ellison Syndrome
Hemorrhage
Ampulla of Vater
16 Citations (Scopus)

Transforming growth factor β and Ras/MEK/ERK signaling regulate the expression level of a novel tumor suppressor lefty

Miyata, N., Azuma, T., Hozawa, S., Higuchi, H., Yokoyama, A., Kabashima, A., Igarashi, T., Saeki, K. & Hibi, T., 2012 Jul, In : Pancreas. 41, 5, p. 745-752 8 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase Kinases
Extracellular Signal-Regulated MAP Kinases
Transforming Growth Factors
Pancreatic Neoplasms
Neoplasms
2011
34 Citations (Scopus)
Insulin
Adiponectin
Insulin Resistance
Logistic Models
Neural networks
2010
13 Citations (Scopus)

Gemcitabine as first-line chemotherapy in elderly patients with unresectable pancreatic carcinoma

Yamagishi, Y., Higuchi, H., Izumiya, M., Sakai, G., Iizuka, H., Nakamura, S., Adachi, M., Hozawa, S., Takaishi, H. & Hibi, T., 2010 Nov, In : Journal of Gastroenterology. 45, 11, p. 1146-1154 9 p.

Research output: Contribution to journalArticle

gemcitabine
Drug Therapy
Pancreatic Neoplasms
Pancreatic Carcinoma
Proportional Hazards Models
2009
100 Citations (Scopus)

Side population of pancreatic cancer cells predominates in TGF-β-mediated epithelial to mesenchymal transition and invasion

Kabashima, A., Higuchi, H., Takaishi, H., Matsuzaki, Y., Suzuki, S., Izumiya, M., Iizuka, H., Sakai, G., Hozawa, S., Azuma, T. & Hibi, T., 2009 Jun 15, In : International Journal of Cancer. 124, 12, p. 2771-2779 9 p.

Research output: Contribution to journalArticle

Side-Population Cells
Epithelial-Mesenchymal Transition
Pancreatic Neoplasms
Population
Cadherins
2008
8 Citations (Scopus)

IgG4-negative autoimmune pancreatitis with sclerosing cholangitis and colitis: Possible association with primary sclerosing cholangitis?

Saeki, K., Hozawa, S., Miyata, N., Nishizawa, T., Soma, H., Iwao, Y., Kameyama, K. & Hibi, T., 2008, In : Internal Medicine. 47, 10, p. 943-948 6 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Colitis
Pancreatitis
Immunoglobulin G
Intrahepatic Bile Ducts
7 Citations (Scopus)

Induction of matrix metalloproteinase-1 gene transcription by tumour necrosis factor α via the p50/p50 homodimer of nuclear factor-κ B in activated human hepatic stellate cells

Hozawa, S., Nakamura, T., Nakano, M., Adachi, M., Tanaka, H., Takahashi, Y., Tetsuya, M., Miyata, N., Soma, H. & Hibi, T., 2008, In : Liver International. 28, 10, p. 1418-1425 8 p.

Research output: Contribution to journalArticle

Hepatic Stellate Cells
Matrix Metalloproteinase 1
Tumor Necrosis Factor-alpha
Genes
Electrophoretic Mobility Shift Assay
2006

A case of tuberculous lymphadenitis found as an abdominal mass penetrating the duodenum

Tokiwa, K., Hozawa, S., Kojima, S., Kobayashi, K., Watanabe, K., Mine, T., Kijima, H., Imai, Y. & Miyachi, H., 2006, In : Japanese Journal of Gastroenterology. 103, 8, p. 948-954 7 p.

Research output: Contribution to journalArticle

Lymph Node Tuberculosis
Duodenum
Tuberculosis
Biopsy
Endosonography
2005
1 Citation (Scopus)

Refractory gastric varices treated by multi-endovascular and endoscopic techniques

Hashimoto, T., Koizumi, J., Hozawa, S., Saito, T., Tokiwa, K., Shiba, T., Mine, T. & Imai, Y., 2005, In : Acta Hepatologica Japonica. 46, 5, p. 284-289 6 p.

Research output: Contribution to journalArticle

Endovascular Procedures
Esophageal and Gastric Varices
Transjugular Intrahepatic Portasystemic Shunt
Hematemesis
Veins
2004
41 Citations (Scopus)

Deficiency of inducible nitric oxide synthase exacerbates hepatic fibrosis in mice fed high-fat diet

Chen, Y., Hozawa, S., Sawamura, S., Sato, S., Fukuyama, N., Tsuji, C., Mine, T., Okada, Y., Tanino, R., Ogushi, Y. & Nakazawa, H., 2004 Dec 31, In : Biochemical and Biophysical Research Communications. 326, 1, p. 45-51 7 p.

Research output: Contribution to journalArticle

High Fat Diet
Nitric Oxide Synthase Type II
Nutrition
Fibrosis
Fats
2003
14 Citations (Scopus)

Pro-inflammatory cytokine-induced matrix metalloproteinase-1 (mmp-1) secretion in human pancreatic periacinar myofibroblasts

Tasaki, K., Shintani, Y., Saotome, T., Andoh, A., Fujiyama, Y., Hozawa, S. & Bamba, T., 2003, In : Pancreatology. 3, 5, p. 414-421 8 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 1
Myofibroblasts
Cytokines
Interleukin-1
Mitogen-Activated Protein Kinase Kinases
5 Citations (Scopus)

Stem Cells Expressing Matrix Metalloproteinase-13 mRNA Appear during Regression Reversal of Hepatic Cirrhosis

Watanabe, T., Niioka, M., Hozawa, S., Sugioka, Y., Arai, M., Maruyama, K., Okano, H. & Okazaki, I., 2003 Feb 6, Extracellular Matrix and The Liver: Approach to Gene Therapy. Elsevier Inc., p. 361-388 28 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Matrix Metalloproteinase 13
Stem cells
Liver Cirrhosis
Liver
Stem Cells
2001
58 Citations (Scopus)

Dynamic change of cells expressing MMP-2 mRNA and MT1-MMP mRNA in the recovery from liver fibrosis in the rat

Watanabe, T., Niioka, M., Ishikawa, A., Hozawa, S., Arai, M., Maruyama, K., Okada, A. & Okazaki, I., 2001, In : Journal of Hepatology. 35, 4, p. 465-473 9 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 15
Matrix Metalloproteinases
Liver Cirrhosis
Messenger RNA
Gelatinases
46 Citations (Scopus)

Reversibility of hepatic fibrosis: From the first report of collagenase in the liver to the possibility of gene therapy for recovery

Okazaki, I., Watanabe, T., Hozawa, S., Niioka, M., Arai, M. & Maruyama, K., 2001 Jun, In : Keio Journal of Medicine. 50, 2, p. 58-65 8 p.

Research output: Contribution to journalArticle

Collagenases
Genetic Therapy
Fibrosis
Liver
Liver Cirrhosis
2000
109 Citations (Scopus)

Gene expression of interstitial collagenase in both progressive and recovery phase of rat liver fibrosis induced by carbon tetrachloride

Watanabe, T., Niioka, M., Hozawa, S., Kameyama, K., Hayashi, T., Arai, M., Ishikawa, A., Maruyama, K. & Okazaki, I., 2000 Aug, In : Journal of Hepatology. 33, 2, p. 224-235 12 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 1
Carbon Tetrachloride
Matrix Metalloproteinases
Liver Cirrhosis
Gene Expression
74 Citations (Scopus)

Molecular mechanism of the reversibility of hepatic fibrosis: With special reference to the role of matrix metalloproteinases

Okazaki, I., Watanabe, T., Hozawa, S., Arai, M. & Maruyama, K., 2000, In : Journal of Gastroenterology and Hepatology (Australia). 15, SUPPL.

Research output: Contribution to journalArticle

Matrix Metalloproteinases
Fibrosis
Matrix Metalloproteinase 1
Liver
Tissue Inhibitor of Metalloproteinases
1999
44 Citations (Scopus)

Interferon-inducible gene family 1-8U expression in colitis-associated colon cancer and severely inflamed mucosa in ulcerative colitis

Hisamatsu, T., Watanabe, M., Ogata, H., Ezaki, T., Hozawa, S., Ishii, H., Kanai, T. & Hibi, T., 1999 Dec 1, In : Cancer Research. 59, 23, p. 5927-5931 5 p.

Research output: Contribution to journalArticle

Colitis
Ulcerative Colitis
Colonic Neoplasms
Interferons
Mucous Membrane