• 8905 Citations
  • 51 h-Index
1992 …2020

Research output per year

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Research Output

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Article

[Risk factors of severe peripheral corneal ulcers].

Suzuki, A., Matsumoto, Y., Uchino, Y., Kawakita, T., Shimmura, S. & Tsubota, K., 2011 Feb 1, In : Nippon Ganka Gakkai zasshi. 115, 2, p. 116-121 6 p.

Research output: Contribution to journalArticle

Accessory cell populations in the cornea

Shimmura, S. & Kawakita, T., 2006 Apr, In : Ocular Surface. 4, 2, p. 74-80 7 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Accumulation of Secretory Vesicles in the Lacrimal Gland Epithelia Is Related to Non-Sjögren's Type Dry Eye in Visual Display Terminal Users

Kamoi, M., Ogawa, Y., Nakamura, S., Dogru, M., Nagai, T., Obata, H., Ito, M., Kaido, M., Kawakita, T., Okada, Y., Kawakami, Y., Shimmura, S. & Tsubota, K., 2012 Sep 4, In : PloS one. 7, 9, e43688.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Acidic electrolysed water in the disinfection of the ocular surface

Shimmura, S., Matsumoto, K., Yaguchi, H., Okuda, T., Miyajima, S., Negi, A., Shimazaki, J. & Tsubot, K., 2000 Jan, In : Experimental Eye Research. 70, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

A Clinical Case Report Including In Vivo Laser Confocal Microscopic Findings of Keratitis Complicated with Takayasu's Arteritis

Matsumoto, Y., Yasuoka, H., Ichihashi, Y., Kawakita, T., Shimmura, S. & Tsubota, K., 2016 Feb 1, In : Nippon Ganka Gakkai zasshi. 120, 2, p. 114-119 6 p.

Research output: Contribution to journalArticle

Albumin as a tear supplement in the treatment of severe dry eye

Shimmura, S., Ueno, R., Matsumoto, Y., Goto, E., Higuchi, A., Shimazaki, J. & Tsubota, K., 2003 Oct 1, In : British Journal of Ophthalmology. 87, 10, p. 1279-1283 5 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

Albumin rescues ocular epithelial cells from cell death in dry eye

Higuchi, A., Ueno, R., Shimmura, S., Suematsu, M., Dogru, M. & Tsubota, K., 2007 Feb 1, In : Current Eye Research. 32, 2, p. 83-88 6 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)
34 Citations (Scopus)

Amniotic membrane transplantation with conjunctival autograft for recurrent pterygium

Shimazaki, J., Kosaka, K., Shimmura, S. & Tsubota, K., 2003 Jan 1, In : Ophthalmology. 110, 1, p. 119-124 6 p.

Research output: Contribution to journalArticle

64 Citations (Scopus)

AMPK-NF-κB axis in the photoreceptor disorder during retinal inflammation

Kamoshita, M., Ozawa, Y., Kubota, S., Miyake, S., Tsuda, C., Nagai, N., Yuki, K., Shimmura, S., Umezawa, K. & Tsubota, K., 2014 Jul 21, In : PloS one. 9, 7, e103013.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Angiotensin II Type 1 Receptor Antagonist Attenuates Lacrimal Gland, Lung, and Liver Fibrosis in a Murine Model of Chronic Graft-Versus-Host Disease

Yaguchi, S., Ogawa, Y., Shimmura, S., Kawakita, T., Hatou, S., Satofuka, S., Nakamura, S., Imada, T., Miyashita, H., Yoshida, S., Yaguchi, T., Ozawa, Y., Mori, T., Okamoto, S., Kawakami, Y., Ishida, S. & Tsubota, K., 2013 Jun 6, In : PloS one. 8, 6, e64724.

Research output: Contribution to journalArticle

30 Citations (Scopus)

A novel NIH/3T3 duplex feeder system to engineer corneal epithelial sheets with enhanced cytokeratin 15-positive progenitor populations

Miyashita, H., Shimmura, S., Higa, K., Yoshida, S., Kawakita, T., Shimazaki, J. & Tsubota, K., 2008 Jul 1, In : Tissue Engineering - Part A.. 14, 7, p. 1275-1282 8 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Antiinflammatory effects of amniotic membrane transplantation in ocular surface disorders

Shimmura, S., Shimazaki, J., Ohashi, Y. & Tsubota, K., 2001 May 9, In : Cornea. 20, 4, p. 408-413 6 p.

Research output: Contribution to journalArticle

201 Citations (Scopus)

Aquaporin 1-positive stromal niche-like cells directly interact with N-cadherin-positive clusters in the basal limbal epithelium

Higa, K., Kato, N., Yoshida, S., Ogawa, Y., Shimazaki, J., Tsubota, K. & Shimmura, S., 2013 Mar 1, In : Stem Cell Research. 10, 2, p. 147-155 9 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

A Rabbit Corneal Endothelial Dysfunction Model Using Endothelial-Mesenchymal Transformed Cells

Yamashita, K., Hatou, S., Inagaki, E., Higa, K., Tsubota, K. & Shimmura, S., 2018 Dec 1, In : Scientific Reports. 8, 1, 16868.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Artificial human corneas: Scaffolds for transplantation and host regeneration

Griffith, M., Hakim, M., Shimmura, S., Watsky, M. A., Li, F., Carlsson, D., Doillon, C. J., Nakamura, M., Suuronen, E., Shinozaki, N., Nakata, K. & Sheardown, H., 2002 Oct, In : Cornea. 21, 7 SUPPL., p. S54-S61

Research output: Contribution to journalArticle

90 Citations (Scopus)

Association between meibomian gland changes and aging, sex, or tear function

Den, S., Shimizu, K., Ikeda, T., Tsubota, K., Shimmura, S. & Shimazaki, J., 2006 Jul 1, In : Cornea. 25, 6, p. 651-655 5 p.

Research output: Contribution to journalArticle

109 Citations (Scopus)

Association of preoperative tear function with surgical outcome in severe Stevens-Johnson syndrome

Shimazaki, J., Shimmura, S., Fujishima, H. & Tsubota, K., 2000 Nov 20, In : Ophthalmology. 107, 8, p. 1518-1523 6 p.

Research output: Contribution to journalArticle

80 Citations (Scopus)

Calorie restriction: A new therapeutic intervention for age-related dry eye disease in rats

Kawashima, M., Kawakita, T., Okada, N., Ogawa, Y., Murat, D., Nakamura, S., Nakashima, H., Shimmura, S., Shinmura, K. & Tsubota, K., 2010 Jul 1, In : Biochemical and Biophysical Research Communications. 397, 4, p. 724-728 5 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Cataract surgery after deep anterior lamellar keratoplasty and penetrating keratoplasty in age- and disease-matched eyes

Den, S., Shimmura, S. & Shimazaki, J., 2018 Apr, In : Journal of Cataract and Refractive Surgery. 44, 4, p. 496-503 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Challenges and Strategies for Regenerating the Lacrimal Gland

Hirayama, M., Kawakita, T., Tsubota, K. & Shimmura, S., 2016 Apr 1, In : Ocular Surface. 14, 2, p. 135-143 9 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Changes in ocular surface caused by antiglaucomatous eyedrops: Prospective, randomised study for the comparison of 0.5% timolol v 0.12% unoprostone

Shimazaki, J., Hanada, K., Yagi, Y., Yamagami, J., Ishioka, M., Shimmura, S. & Tsubota, K., 2000 Nov 16, In : British Journal of Ophthalmology. 84, 11, p. 1250-1254 5 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Changes observed in keratolimbal allograft

Maruyama-Hosoi, F., Shimazaki, J., Shimmura, S. & Tsubota, K., 2006 May 1, In : Cornea. 25, 4, p. 377-382 6 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Characteristics of Traumatic Globe Rupture after Keratoplasty

Kawashima, M., Kawakita, T., Shimmura, S., Tsubota, K. & Shimazaki, J., 2009 Nov 1, In : Ophthalmology. 116, 11, p. 2072-2076 5 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Characterization of cultivated murine lacrimal gland epithelial cells

Kobayashi, S., Kawakita, T., Kawashima, M., Okada, N., Mishima, K., Saito, I., Ito, M., Shimmura, S. & Tsubota, K., 2012 May 12, In : Molecular vision. 18, p. 1271-1277 7 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Clinical application of Er:YAG laser for the treatment of pterygium

Nakamura, K., Bissen-Miyajima, H., Shimmura, S. & Tsubota, K., 2000 Jan 1, In : Ophthalmic Surgery and Lasers. 31, 1, p. 8-12 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Clinical application of living-related conjunctival-limbal allograft

Tsubota, K., Shimmura, S., Shinozaki, N., Holland, E. J. & Shimazaki, J., 2002 Jan 1, In : American Journal of Ophthalmology. 133, 1, p. 134-135 2 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Clinical backgrounds of postoperative keratoplasty patients with spontaneous wound dehiscence or gaps after suture removal

Fujii, S., Matsumoto, Y., Fukui, M., Fujitake, J., Kawakita, T., Shimmura, S. & Tsubota, K., 2014 Jan 1, In : Cornea. 33, 12, p. 1320-1323 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Clusterin promotes corneal epithelial cell growth through upregulation of hepatocyte growth factor by mesenchymal cells in vitro

Okada, N., Kawakita, T., Mishima, K., Saito, I., Miyashita, H., Yoshida, S., Shimmura, S. & Tsubota, K., 2011 May 1, In : Investigative Ophthalmology and Visual Science. 52, 6, p. 2905-2910 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Collagen-immobilized poly(vinyl alcohol) as an artificial cornea scaffold that supports a stratified corneal epithelium

Miyashita, H., Shimmura, S., Kobayashi, H., Taguchi, T., Asano-Kato, N., Uchino, Y., Kato, M., Shimazaki, J., Tanaka, J. & Tsubota, K., 2006 Jan 1, In : Journal of Biomedical Materials Research - Part B Applied Biomaterials. 76, 1, p. 56-63 8 p.

Research output: Contribution to journalArticle

66 Citations (Scopus)

Collagen immobilized PVA hydrogel-hydroxyapatite composites prepared by kneading methods as a material for peripheral cuff of artificial cornea

Kobayashi, H., Kato, M., Taguchi, T., Ikoma, T., Miyashita, H., Shimmura, S., Tsubota, K. & Tanaka, J., 2004 Dec 1, In : Materials Science and Engineering C. 24, 6-8 SPEC. ISS., p. 729-735 7 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)

Collagen-poly(N-isopropylacrylamide)-based membranes for corneal stroma scaffolds

Shimmura, S., Doillon, C. J., Griffith, M., Nakamura, M., Gagnon, E., Usui, A., Shinozaki, N. & Tsubota, K., 2003 Oct, In : Cornea. 22, 7 SUPPL., p. S81-S88

Research output: Contribution to journalArticle

35 Citations (Scopus)

Comparison of anterior and posterior corneal surface irregularity in descemet stripping automated endothelial keratoplasty and penetrating keratoplasty

Yamaguchi, T., Negishi, K., Yamaguchi, K., Dogru, M., Uchino, Y., Shimmura, S. & Tsubota, K., 2010 Oct 1, In : Cornea. 29, 10, p. 1086-1090 5 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Comparison of corneal thickness and haze in DSAEK and penetrating keratoplasty

Uchino, Y., Shimmura, S., Yamaguchi, T., Kawakita, T., Matsumoto, Y., Negishi, K. & Tsubota, K., 2011 Mar 1, In : Cornea. 30, 3, p. 287-290 4 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Comparison of Deep Lamellar Keratoplasty and Penetrating Keratoplasty for Lattice and Macular Corneal Dystrophies

Kawashima, M., Kawakita, T., Den, S., Shimmura, S., Tsubota, K. & Shimazaki, J., 2006 Aug 1, In : American Journal of Ophthalmology. 142, 2, p. 304-309 6 p.

Research output: Contribution to journalArticle

67 Citations (Scopus)

Comparison of domestic and overseas donor corneas for keratoplasty

Nishi, Y., Kawakita, T., Yasu, M., Ichihashi, Y., Matsumoto, Y., Shimmura, S. & Tsubota, K., 2012 Sep 1, In : Japanese Journal of Clinical Ophthalmology. 66, 9, p. 1337-1342 6 p.

Research output: Contribution to journalArticle

Comparison of long-term outcome of penetrating and deep anterior lamellar keratoplasty

Adachi, S., Ichihashi, Y., Kawakita, T., Matsumoto, Y., Uchino, M., Shimmura, S. & Tsubota, K., 2013 Jan 1, In : Japanese Journal of Clinical Ophthalmology. 67, 1, p. 85-89 5 p.

Research output: Contribution to journalArticle

Comparison of Long-Term Outcomes of Visual Function and Endothelial Cell Survival After Descemet Stripping Automated Endothelial Keratoplasty and Penetrating Keratoplasty Using Mixed-Effects Models

Ishiyama, S., Mori, Y., Nejima, R., Tokudome, T., Shimmura, S., Miyata, K. & Amano, S., 2016 Aug 24, (Accepted/In press) In : Cornea.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Comparison of telomere length and association with progenitor cell markers in lacrimal gland between sjögren syndrome and non-sjögren syndrome dry eye patients

Kawashima, M., Kawakita, T., Maida, Y., Kamoi, M., Ogawa, Y., Shimmura, S., Masutomi, K. & Tsubota, K., 2011 Jun 22, In : Molecular vision. 17, p. 1397-1404 8 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Complications with one-piece lamellar keratolimbal grafts for simultaneous limbal and corneal pathologies

Shimmura, S., Ando, M., Shimazaki, J. & Tsubota, K., 2000 Jul 1, In : Cornea. 19, 4, p. 439-442 4 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Component surgery of the cornea

Shimmura, S., 2004 Nov, In : Cornea. 23, 8 SUPPL., p. S31-S35

Research output: Contribution to journalArticle

28 Citations (Scopus)

Corneal Endothelial Regeneration Using Mesenchymal Stem Cells Derived from Human Umbilical Cord

Yamashita, K., Inagaki, E., Hatou, S., Higa, K., Ogawa, A., Miyashita, H., Tsubota, K. & Shimmura, S., 2018 Aug 15, In : Stem Cells and Development. 27, 16, p. 1097-1108 12 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Corneal opacity and cataract: Triple procedure versus secondary approach

Shimmura, S., Ohashi, Y., Shiroma, H., Shimazaki, J. & Tsubota, K., 2003 Apr 1, In : Cornea. 22, 3, p. 234-238 5 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Cultivated autologous limbal epithelial transplantation for symptomatic bullous keratopathy

Satake, Y., Shimmura, S. & Shimazaki, J., 2009 Apr 14, In : BMJ case reports.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Cytokeratin 15 can be used to identify the limbal phenotype in normal and diseased ocular surfaces

Yoshida, S., Shimmura, S., Kawakita, T., Miyashita, H., Den, S., Shimazaki, J. & Tsubota, K., 2006 Nov 1, In : Investigative Ophthalmology and Visual Science. 47, 11, p. 4780-4786 7 p.

Research output: Contribution to journalArticle

116 Citations (Scopus)

Cytokeratin expression in mouse lacrimal gland germ epithelium

Hirayama, M., Liu, Y., Kawakita, T., Shimmura, S. & Tsubota, K., 2016 May 1, In : Experimental Eye Research. 146, p. 54-59 6 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Dacryoadenitis associated with Acanthamoeba keratitis

Tomita, M., Shimmura, S., Tsubota, K. & Shimazaki, J., 2006 Sep 19, In : Archives of Ophthalmology. 124, 9, p. 1239-1242 4 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Deep lamellar keratoplasty (DLKP) in keratoconus patients using viscoadaptive viscoelastics

Shimmura, S., Shimazaki, J., Omoto, M., Teruya, A., Ishioka, M. & Tsubota, K., 2005 Mar 1, In : Cornea. 24, 2, p. 178-181 4 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)

Deep lamellar keratoplasty in severe ocular surface disease

Shimmura, S., Higa, A., Omoto, M., Shimazaki, J. & Tsubota, K., 2007 May, In : Nippon Ganka Gakkai zasshi. 111, 5, p. 391-396 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Detection of neutrophils and possible involvement of interleukin-8 in diffuse lamellar keratitis after laser in situ keratomileusis

Asano-Kato, N., Toda, I., Shimmura, S., Noda-Tsuruya, T., Fukagawa, K., Yoshinaga, M., Matsukawa, A. & Tsubota, K., 2003 Oct, In : Journal of Cataract and Refractive Surgery. 29, 10, p. 1996-2000 5 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)