• 458 Citations
  • 12 h-Index
20102019

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

  • 458 Citations
  • 12 h-Index
  • 30 Article
Filter
Article
2019

A phase II trial of induction of erlotinib followed by cytotoxic chemotherapy for EGFR mutation-positive non-squamous non-small cell lung cancer patients

Tani, T., Naoki, K., Yasuda, H., Arai, D., Ishioka, K., Ohgino, K., Yoda, S., Nakayama, S., Satomi, R., Terai, H., Ikemura, S., Sato, T. & Soejima, K., 2019 Nov 1, In : Cancer Chemotherapy and Pharmacology. 84, 5, p. 1065-1071 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Efficacy of afatinib or osimertinib plus cetuximab combination therapy for non-small-cell lung cancer with EGFR exon 20 insertion mutations

Hasegawa, H., Yasuda, H., Hamamoto, J., Masuzawa, K., Tani, T., Nukaga, S., Hirano, T., Kobayashi, K., Manabe, T., Terai, H., Ikemura, S., Kawada, I., Naoki, K. & Soejima, K., 2019 Jan 1, In : Lung Cancer. 127, p. 146-152 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Long-lasting response to nivolumab for a patient with lynch syndrome-associated lung adenocarcinoma

Masuzawa, K., Asakura, T., Ikemura, S., Yasuda, H., Kawada, I., Takaoka, S., Hayashi, Y., Nakajima, T., Arai, M., Fukunaga, K. & Soejima, K., 2019 Jan 1, In : JCO Precision Oncology. 3, p. 74-78 5 p.

Research output: Contribution to journalArticle

Molecular dynamics simulation-guided drug sensitivity prediction for lung cancer with rare EGFR mutations

Ikemura, S., Yasuda, H., Matsumoto, S., Kamada, M., Hamamoto, J., Masuzawa, K., Kobayashi, K., Manabe, T., Arai, D., Nakachi, I., Kawada, I., Ishioka, K., Nakamura, M., Namkoong, H., Naoki, K., Ono, F., Araki, M., Kanada, R., Ma, B., Hayashi, Y. & 8 others, Mimaki, S., Yoh, K., Kobayashi, S. S., Kohno, T., Okuno, Y., Goto, K., Tsuchihara, K. & Soejima, K., 2019 May 14, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 20, p. 10025-10030 6 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Monomer preference of EGFR tyrosine kinase inhibitors influences the synergistic efficacy of combination therapy with cetuximab

Oashi, A., Yasuda, H., Kobayashi, K., Tani, T., Hamamoto, J., Masuzawa, K., Manabe, T., Terai, H., Ikemura, S., Kawada, I., Naoki, K. & Soejima, K., 2019 Jan 1, In : Molecular cancer therapeutics. 18, 9, p. 1593-1601 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2018

A case of pulmonary adenocarcinoma showing rapid progression of peritoneal dissemination after immune checkpoint inhibitor therapy

Shinozaki, T., Iwami, E., Ikemura, S., Matsuzaki, T., Nakajima, T., Hashimoto, K. & Terashima, T., 2018 May 31, In : BMC Cancer. 18, 1, 620.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Lymph node collision tumor consisting of metastatic pulmonary adenocarcinoma and diffuse large b-cell lymphoma

Ikemura, S., Moriyama, M., Matsumoto, K., Nakayama, S., Matsuzaki, T., Nakajima, T., Sasaki, A., Miyauchi, J. & Terashima, T., 2018 Jan 1, In : Internal Medicine. 57, 8, p. 1135-1139 5 p.

Research output: Contribution to journalArticle

2017

Amplification of EGFR wild-type alleles in non-small cell lung cancer cells confers acquired resistance to mutation-selective EGFR tyrosine kinase inhibitors

Nukaga, S., Yasuda, H., Tsuchihara, K., Hamamoto, J., Masuzawa, K., Kawada, I., Naoki, K., Matsumoto, S., Mimaki, S., Ikemura, S., Goto, K., Betsuyaku, T. & Soejima, K., 2017 Apr 15, In : Cancer Research. 77, 8, p. 2078-2089 12 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)

Changes in the tumor microenvironment during lymphatic metastasis of lung squamous cell carcinoma

Ikemura, S., Aramaki, N., Fujii, S., Kirita, K., Umemura, S., Matsumoto, S., Yoh, K., Niho, S., Ohmatsu, H., Kuwata, T., Kojima, M., Ochiai, A., Betsuyaku, T., Tsuboi, M., Goto, K. & Ishii, G., 2017 Jan 1, In : Cancer Science. 108, 1, p. 136-142 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

The prognostic factors for long-term (≥5 Years) survival in stage IV Non-small cell lung cancer

Matsuzaki, T., Ikemura, S., Chubachi, S., Nakayama, S., Iwami, E., Sato, M., Nakajima, T., Eguchi, K. & Terashima, T., 2017 Apr 20, In : Japanese Journal of Lung Cancer. 57, 2, p. 88-95 8 p.

Research output: Contribution to journalArticle

2016

A Case of Small Cell Lung Cancer Treated with Concurrent Chemoradiotherapy with Carboplatin plus Etoposide in a Hemodialysis Patient

Terashima, T., Iwami, E., Chubachi, S., Ikemura, S., Nakajima, T., Matsuzaki, T. & Aoyagi, H., 2016 Jan 1, In : Gan to kagaku ryoho. Cancer & chemotherapy. 43, 1, p. 99-101 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Aggressive tumor microenvironment of solid predominant lung adenocarcinoma subtype harboring with epidermal growth factor receptor mutations

Saruwatari, K., Ikemura, S., Sekihara, K., Kuwata, T., Fujii, S., Umemura, S., Kirita, K., Matsumoto, S., Yoh, K., Niho, S., Ohmatsu, H., Ochiai, A., Kohrogi, H., Tsuboi, M., Goto, K. & Ishii, G., 2016 Jan 1, In : Lung Cancer. 91, p. 7-14 8 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

The association of intravascular stromal cells with prognosis in high-grade neuroendocrine carcinoma of the lung

Sekihara, K., Hishida, T., Ikemura, S., Saruwatari, K., Morise, M., Kuwata, T., Fujii, S., Kojima, M., Ochiai, A., Funai, K., Aokage, K., Yoshida, J., Tsuboi, M. & Ishii, G., 2016 May 1, In : Journal of Cancer Research and Clinical Oncology. 142, 5, p. 905-912 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2015

A phase II study of biweekly paclitaxel and carboplatin in elderly patients with advanced non-small cell lung cancer

Soejima, K., Naoki, K., Ishioka, K., Nakamura, M., Nakatani, M., Kawada, I., Watanabe, H., Nakachi, I., Yasuda, H., Satomi, R., Nakayama, S., Yoda, S., Ikemura, S., Terai, H., Sato, T., Ohgino, K., Arai, D., Tani, T., Kuroda, A., Nishino, M. & 1 others, Betsuyaku, T., 2015 Mar, In : Cancer Chemotherapy and Pharmacology. 75, 3, p. 513-519 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

A Phase II study of S-1 and irinotecan combination therapy in previously treated patients with advanced non-small cell lung cancer

Ikemura, S., Naoki, K., Yasuda, H., Kawada, I., Yoda, S., Terai, H., Sato, T., Ishioka, K., Arai, D., Ohgino, K., Kamata, H., Miyata, J., Kabata, H., Betsuyaku, T. & Soejima, K., 2015 Apr 1, In : Japanese journal of clinical oncology. 45, 4, p. 356-361 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

FOXD1 expression is associated with poor prognosis in non-small cell lung cancer

Nakayama, S., Soejima, K., Yasuda, H., Yoda, S., Satomi, R., Ikemura, S., Terai, H., Sato, T., Yamaguchi, N., Hamamoto, J., Arai, D., Ishioka, K., Ohgino, K., Naoki, K. & Betsuyaku, T., 2015 Jan 1, In : Anticancer research. 35, 1, p. 261-268 8 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Long-term exposure to gefitinib induces acquired resistance through DNA methylation changes in the EGFR-mutant PC9 lung cancer cell line

Terai, H., Soejima, K., Yasuda, H., Sato, T., Naoki, K., Ikemura, S., Arai, D., Ohgino, K., Ishioka, K., Hamamoto, J., Kanai, Y. & Betsuyaku, T., 2015 Jan 1, In : International journal of oncology. 46, 1, p. 430-436 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Methylation-induced downregulation of TFPI-2 causes TMPRSS4 overexpression and contributes to oncogenesis in a subset of non-small-cell lung carcinoma

Hamamoto, J., Soejima, K., Naoki, K., Yasuda, H., Hayashi, Y., Yoda, S., Nakayama, S., Satomi, R., Terai, H., Ikemura, S., Sato, T., Arai, D., Ishioka, K., Ohgino, K. & Betsuyaku, T., 2015 Jan 1, In : Cancer science. 106, 1, p. 34-42 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2014

Claudin-1 is a novel target of miR-375 in non-small-cell lung cancer

Yoda, S., Soejima, K., Hamamoto, J., Yasuda, H., Nakayama, S., Satomi, R., Terai, H., Ikemura, S., Sato, T., Naoki, K. & Betsuyaku, T., 2014 Jan 1, In : Lung Cancer. 85, 3, p. 366-372 7 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Expression of fibroblast growth factor 9 is associated with poor prognosis in patients with resected non-small cell lung cancer

Ohgino, K., Soejima, K., Yasuda, H., Hayashi, Y., Hamamoto, J., Naoki, K., Arai, D., Ishioka, K., Sato, T., Terai, H., Ikemura, S., Yoda, S., Tani, T., Kuroda, A. & Betsuyaku, T., 2014 Jan 1, In : Lung Cancer. 83, 1, p. 90-96 7 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)
2013

[Evaluation of the characteristics of tuberculosis patients in Ashikaga Red Cross Hospital, Tochigi Prefecture, Japan (2007-2011)].

Shimada, M., Kameyama, Y. & Ikemura, S., 2013 Jul, In : Unknown Journal. 88, 7, p. 589-593 5 p.

Research output: Contribution to journalArticle

Activation of the FGF2-FGFR1 autocrine pathway: A novel mechanism of acquired resistance to gefitinib in NSCLC

Terai, H., Soejima, K., Yasuda, H., Nakayama, S., Hamamoto, J., Arai, D., Ishioka, K., Ohgino, K., Ikemura, S., Sato, T., Yoda, S., Satomi, R., Naoki, K. & Betsuyaku, T., 2013 Jul 1, In : Molecular Cancer Research. 11, 7, p. 759-767 9 p.

Research output: Contribution to journalArticle

122 Citations (Scopus)

Identification of microRNAs differentially expressed between lung squamous cell carcinoma and lung adenocarcinoma

Hamamoto, J., Soejima, K., Yoda, S., Naoki, K., Nakayama, S., Satomi, R., Terai, H., Ikemura, S., Sato, T., Yasuda, H., Hayashi, Y., Sakamoto, M., Takebayashi, T. & Betsuyaku, T., 2013 Aug 1, In : Molecular Medicine Reports. 8, 2, p. 456-462 7 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)
2012

A case of elderly advanced squamous cell lung carcinoma successfully treated with nedaplatin and S-1 combination chemotherapy

Terai, H., Soejima, K., Naoki, K., Ikemura, S., Ogura-Tomomatsu, H., Sato, T., Asano, K. & Betsuyaku, T., 2012 Mar, In : Japanese Journal of Cancer and Chemotherapy. 39, 3, p. 429-432 4 p.

Research output: Contribution to journalArticle

2011

A phase i study of S-1 and irinotecan combination therapy in previously treated advanced non-small cell lung cancer patients

Yoda, S., Soejima, K., Yasuda, H., Naoki, K., Kawada, I., Watanabe, H., Nakachi, I., Satomi, R., Nakayama, S., Ikemura, S., Terai, H., Sato, T., Morosawa, M. & Asano, K., 2011 Mar 1, In : Cancer Chemotherapy and Pharmacology. 67, 3, p. 717-722 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Bronchoscopic Microsampling is a Useful Complementary Diagnostic Tool for Detecting Lung Cancer

Yasuda, H., Soejima, K., Nakayama, S., Kawada, I., Nakachi, I., Yoda, S., Satomi, R., Ikemura, S., Terai, H., Sato, T., Watanabe, H., Naoki, K., Hayashi, Y. & Ishizaka, A., 2011 Apr 1, In : Lung Cancer. 72, 1, p. 32-38 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

The PCR-invader method (structure-specific 5 nuclease-based method), a sensitive method for detecting EGFR gene mutations in lung cancer specimens; Comparison with direct sequencing

Naoki, K., Soejima, K., Okamoto, H., Hamamoto, J., Hida, N., Nakachi, I., Yasuda, H., Nakayama, S., Yoda, S., Satomi, R., Ikemura, S., Terai, H., Sato, T. & Watanabe, K., 2011 Aug 1, In : International Journal of Clinical Oncology. 16, 4, p. 335-344 10 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)
2010

Distinct epigenetic regulation of tumor suppressor genes in putative cancer stem cells of solid tumors

Yasuda, H., Soejima, K., Watanabe, H., Kawada, I., Nakachi, I., Yoda, S., Nakayama, S., Satomi, R., Ikemura, S., Terai, H., Sato, T., Suzuki, S., Matsuzaki, Y., Naoki, K. & Ishizaka, A., 2010 Dec 1, In : International journal of oncology. 37, 6, p. 1537-1546 10 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

FDG-PET imaging of benign pulmonary diseases

Terai, H., Soejima, K., Naoki, K., Kawada, I., Nakachi, I., Satomi, R., Nakayama, S., Yoda, S., Ikemura, S., Sato, T., Ishizaka, A. & Yasuda, H., 2010 Feb 15, In : Japanese Journal of Clinical Radiology. 55, 1, p. 163-172 10 p.

Research output: Contribution to journalArticle

The combination of multiple receptor tyrosine kinase inhibitor and mammalian target of rapamycin inhibitor overcomes erlotinib resistance in lung cancer cell lines through c-met inhibition

Nakachi, I., Naoki, K., Soejima, K., Kawada, I., Watanabe, H., Yasuda, H., Nakayama, S., Yoda, S., Satomi, R., Ikemura, S., Terai, H., Sato, T. & Ishizaka, A., 2010 Aug 1, In : Molecular Cancer Research. 8, 8, p. 1142-1151 10 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)