Research Output per year
Fingerprint Dive into the research topics where Tadahiko Mashino is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Fullerenes
Medicine & Life Sciences
Derivatives
Chemical Compounds
Cytochrome P-450 Enzyme System
Chemical Compounds
Superoxides
Chemical Compounds
Reactive Oxygen Species
Medicine & Life Sciences
Alkenes
Medicine & Life Sciences
Chemical activation
Chemical Compounds
Oxidation
Chemical Compounds
Network
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Research Output 1983 2019
Synthesis and antitumor activity of novel pyridinium fullerene derivatives
Yasuno, T., Ohe, T., Ikeda, H., Takahashi, K., Nakamura, S. & Mashino, T., 2019 Jan 1, In : International journal of nanomedicine. 14, p. 6325-6337 13 p.Research output: Contribution to journal › Article
Open Access
Fullerenes
Derivatives
Heterografts
Cell Line
Lead compounds
3
Citations
(Scopus)
A 5-hydroxyoxindole derivative attenuates LPS-induced inflammatory responses by activating the p38-Nrf2 signaling axis
Niino, T., Tago, K., Yasuda, D., Takahashi, K., Mashino, T., Tamura, H. & Tago, M., 2018 Sep 1, In : Biochemical Pharmacology. 155, p. 182-197 16 p.Research output: Contribution to journal › Article
Derivatives
Acetylcysteine
Cysteine
Chemical activation
Antioxidants
A major component of vitamin E, α-tocopherol inhibits the anti-tumor activity of crizotinib against cells transformed by EML4-ALK
Uchihara, Y., Kidokoro, T., Tago, K., Mashino, T., Tamura, H. & Tago, M., 2018 Apr 15, In : European Journal of Pharmacology. 825, p. 1-9 9 p.Research output: Contribution to journal › Article
Tocopherols
Vitamin E
Neoplasms
Tocotrienols
Gene Fusion
Hit-to-Lead in Academia: Discovery of a Protein-Protein Interaction Inhibitor of Keap1-Nrf2
Yasuda, D., Obata, R., Takahashi, K., Ohe, T. & Mashino, T., 2018 Jan 1, In : Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 138, 8, p. 1059-1065 7 p.Research output: Contribution to journal › Review article
Proteins
Drug Discovery
Kelch-Like ECH-Associated Protein 1
Lead
Protein Stability
Synthesis of novel benzbromarone derivatives designed to avoid metabolic activation
Ohe, T., Umezawa, R., Kitagawara, Y., Yasuda, D., Takahashi, K., Nakamura, S., Abe, A., Sekine, S., Ito, K., Okunushi, K., Morio, H., Furihata, T., Anzai, N. & Mashino, T., 2018 Jan 1, (Accepted/In press) In : Bioorganic and Medicinal Chemistry Letters.Research output: Contribution to journal › Article
Benzbromarone
Uricosuric Agents
Chemical activation
Derivatives
Uric Acid