• 2624 Citations
  • 30 h-Index
1983 …2019
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Fingerprint Dive into the research topics where Tadahiko Mashino is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 4 Similar Profiles
Fullerenes Medicine & Life Sciences
Derivatives Chemical Compounds
Cytochrome P-450 Enzyme System Chemical Compounds
Superoxides Chemical Compounds
Reactive Oxygen Species Medicine & Life Sciences
Alkenes Medicine & Life Sciences
Chemical activation Chemical Compounds
Oxidation Chemical Compounds

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Research Output 1983 2019

  • 2624 Citations
  • 30 h-Index
  • 95 Article
  • 2 Review article
  • 1 Chapter
  • 1 Conference contribution

Synthesis and antitumor activity of novel pyridinium fullerene derivatives

Yasuno, T., Ohe, T., Ikeda, H., Takahashi, K., Nakamura, S. & Mashino, T., 2019 Jan 1, In : International journal of nanomedicine. 14, p. 6325-6337 13 p.

Research output: Contribution to journalArticle

Open Access
Cell Line
Lead compounds
3 Citations (Scopus)

A 5-hydroxyoxindole derivative attenuates LPS-induced inflammatory responses by activating the p38-Nrf2 signaling axis

Niino, T., Tago, K., Yasuda, D., Takahashi, K., Mashino, T., Tamura, H. & Tago, M., 2018 Sep 1, In : Biochemical Pharmacology. 155, p. 182-197 16 p.

Research output: Contribution to journalArticle

Chemical activation

A major component of vitamin E, α-tocopherol inhibits the anti-tumor activity of crizotinib against cells transformed by EML4-ALK

Uchihara, Y., Kidokoro, T., Tago, K., Mashino, T., Tamura, H. & Tago, M., 2018 Apr 15, In : European Journal of Pharmacology. 825, p. 1-9 9 p.

Research output: Contribution to journalArticle

Vitamin E
Gene Fusion

Hit-to-Lead in Academia: Discovery of a Protein-Protein Interaction Inhibitor of Keap1-Nrf2

Yasuda, D., Obata, R., Takahashi, K., Ohe, T. & Mashino, T., 2018 Jan 1, In : Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 138, 8, p. 1059-1065 7 p.

Research output: Contribution to journalReview article

Drug Discovery
Kelch-Like ECH-Associated Protein 1
Protein Stability

Synthesis of novel benzbromarone derivatives designed to avoid metabolic activation

Ohe, T., Umezawa, R., Kitagawara, Y., Yasuda, D., Takahashi, K., Nakamura, S., Abe, A., Sekine, S., Ito, K., Okunushi, K., Morio, H., Furihata, T., Anzai, N. & Mashino, T., 2018 Jan 1, (Accepted/In press) In : Bioorganic and Medicinal Chemistry Letters.

Research output: Contribution to journalArticle

Uricosuric Agents
Chemical activation
Uric Acid