Research Output per year
Research Output
2020
The NOTCH–FOXM1 axis plays a key role in mitochondrial biogenesis in the induction of human stem cell memory–like CAR-T cells
Kondo, T., Ando, M., Nagai, N., Tomisato, W., Srirat, T., Liu, B., Mise-Omata, S., Ikeda, M., Chikuma, S., Nishimasu, H., Nureki, O., Ohmura, M., Hayakawa, N., Hishiki, T., Uchibori, R., Ozawa, K. & Yoshimura, A., 2020 Feb 1, In : Cancer Research. 80, 3, p. 471-483 13 p.Research output: Contribution to journal › Article
2
Citations
(Scopus)
2019
Xanthine oxidase inhibitor ameliorates postischemic renal injury in mice by promoting resynthesis of adenine nucleotides
Fujii, K., Kubo, A., Miyashita, K., Sato, M., Hagiwara, A., Inoue, H., Ryuzaki, M., Tamaki, M., Hishiki, T., Hayakawa, N., Kabe, Y., Itoh, H. & Suematsu, M., 2019 Nov 14, In : JCI Insight. 4, 22, e124816.Research output: Contribution to journal › Article
Open Access
1
Citation
(Scopus)
2018
Biochemical, metabolomic, and genetic analyses of dephospho coenzyme a kinase involved in coenzyme a biosynthesis in the human enteric parasite entamoeba histolytica
Nurkanto, A., Jeelani, G., Yamamoto, T., Hishiki, T., Naito, Y., Suematsu, M., Hashimoto, T. & Nozaki, T., 2018 Nov 30, In : Frontiers in Microbiology. 9, NOV, 2902.Research output: Contribution to journal › Article
2
Citations
(Scopus)
Characterization and validation of Entamoeba histolytica pantothenate kinase as a novel anti-amebic drug target
Nurkanto, A., Jeelani, G., Yamamoto, T., Naito, Y., Hishiki, T., Mori, M., Suematsu, M., Shiomi, K., Hashimoto, T. & Nozaki, T., 2018 Apr, In : International Journal for Parasitology: Drugs and Drug Resistance. 8, 1, p. 125-136 12 p.Research output: Contribution to journal › Article
3
Citations
(Scopus)
Development of a highly sensitive device for counting the number of disease-specific exosomes in human sera
Kabe, Y., Suematsu, M., Sakamoto, S., Hirai, M., Koike, I., Hishiki, T., Matsuda, A., Hasegawa, Y., Tsujita, K., Ono, M., Minegishi, N., Hozawa, A., Murakami, Y., Kubo, M., Itonaga, M. & Handa, H., 2018 Oct, In : Clinical Chemistry. 64, 10, p. 1463-1473 11 p.Research output: Contribution to journal › Article
11
Citations
(Scopus)
Glucose is preferentially utilized for biomass synthesis in pressure-overloaded hearts: Evidence from fatty acid-binding protein-4 and-5 knockout mice
Umbarawan, Y., Syamsunarno, M. R. A. A., Koitabashi, N., Yamaguchi, A., Hanaoka, H., Hishiki, T., Nagahata-Naito, Y., Obinata, H., Sano, M., Sunaga, H., Matsui, H., Tsushima, Y., Suematsu, M., Kurabayashi, M. & Iso, T., 2018 Jul 1, In : Cardiovascular Research. 114, 8, p. 1132-1144 13 p.Research output: Contribution to journal › Article
6
Citations
(Scopus)
Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival
Shiota, M., Naya, M., Yamamoto, T., Hishiki, T., Tani, T., Takahashi, H., Kubo, A., Koike, D., Itoh, M., Ohmura, M., Kabe, Y., Sugiura, Y., Hiraoka, N., Morikawa, T., Takubo, K., Suina, K., Nagashima, H., Sampetrean, O., Nagano, O., Saya, H. & 3 others, , 2018 Dec 1, In : Nature Communications. 9, 1, 1561.Research output: Contribution to journal › Article
26
Citations
(Scopus)
Myocardial fatty acid uptake through CD36 is indispensable for sufficient bioenergetic metabolism to prevent progression of pressure overload-induced heart failure
Umbarawan, Y., Syamsunarno, M. R. A. A., Koitabashi, N., Obinata, H., Yamaguchi, A., Hanaoka, H., Hishiki, T., Hayakawa, N., Sano, M., Sunaga, H., Matsui, H., Tsushima, Y., Suematsu, M., Kurabayashi, M. & Iso, T., 2018 Dec 1, In : Scientific reports. 8, 1, 12035.Research output: Contribution to journal › Article
7
Citations
(Scopus)
Neuroprotective Role of Astroglia in Parkinson Disease by Reducing Oxidative Stress Through Dopamine-Induced Activation of Pentose-Phosphate Pathway
Mashima, K., Takahashi, S., Minami, K., Izawa, Y., Abe, T., Tsukada, N., Hishiki, T., Suematsu, M., Kajimura, M. & Suzuki, N., 2018 May 1, In : ASN Neuro. 10Research output: Contribution to journal › Article
8
Citations
(Scopus)
2017
Robust suppression of cardiac energy catabolism with marked accumulation of energy substrates during lipopolysaccharide-induced cardiac dysfunction in mice
Umbarawan, Y., Syamsunarno, M. R. A. A., Obinata, H., Yamaguchi, A., Sunaga, H., Matsui, H., Hishiki, T., Matsuura, T., Koitabashi, N., Obokata, M., Hanaoka, H., Haque, A., Kunimoto, F., Tsushima, Y., Suematsu, M., Kurabayashi, M. & Iso, T., 2017 Dec, In : Metabolism: clinical and experimental. 77, p. 47-57 11 p.Research output: Contribution to journal › Article
10
Citations
(Scopus)
Targeting oxygen-sensing prolyl hydroxylase for metformin-associated lactic acidosis treatment
Oyaizu-Toramaru, T., Suhara, T., Hayakawa, N., Nakamura, T., Kubo, A., Minamishima, S., Yamaguchi, K., Hishiki, T., Morisaki, H., Suematsu, M. & Minamishima, Y., 2017 Aug 1, In : Molecular and Cellular Biology. 37, 16, e00248-17.Research output: Contribution to journal › Article
4
Citations
(Scopus)
The histone 3 lysine 9 methyltransferase inhibitor chaetocin improves prognosis in a rat model of high salt diet-induced heart failure
Ono, T., Kamimura, N., Matsuhashi, T., Nagai, T., Nishiyama, T., Endo, J., Hishiki, T., Nakanishi, T., Shimizu, N., Tanaka, H., Ohta, S., Suematsu, M., Ieda, M., Sano, M., Fukuda, K. & Kaneda, R., 2017 Jan 4, In : Scientific Reports. 7, 39752.Research output: Contribution to journal › Article
12
Citations
(Scopus)
2016
A possible role of microglia-derived nitric oxide by lipopolysaccharide in activation of astroglial pentose-phosphate pathway via the Keap1/Nrf2 system
Iizumi, T., Takahashi, S., Mashima, K., Minami, K., Izawa, Y., Abe, T., Hishiki, T., Suematsu, M., Kajimura, M. & Suzuki, N., 2016 May 4, In : Journal of Neuroinflammation. 13, 1, 99.Research output: Contribution to journal › Article
23
Citations
(Scopus)
Glutamine Oxidation Is Indispensable for Survival of Human Pluripotent Stem Cells
Tohyama, S., Fujita, J., Hishiki, T., Matsuura, T., Hattori, F., Ohno, R., Kanazawa, H., Seki, T., Nakajima, K., Kishino, Y., Okada, M., Hirano, A., Kuroda, T., Yasuda, S., Sato, Y., Yuasa, S., Sano, M., Suematsu, M. & Fukuda, K., 2016 Apr 12, In : Cell Metabolism. 23, 4, p. 663-674 12 p.Research output: Contribution to journal › Article
68
Citations
(Scopus)
2015
Activation of pyruvate dehydrogenase by dichloroacetate has the potential to induce epigenetic remodeling in the heart
Matsuhashi, T., Hishiki, T., Zhou, H., Ono, T., Kaneda, R., Iso, T., Yamaguchi, A., Endo, J., Katsumata, Y., Atsushi, A., Yamamoto, T., Shirakawa, K., Yan, X., Shinmura, K., Suematsu, M., Fukuda, K. & Sano, M., 2015 May 1, In : Journal of Molecular and Cellular Cardiology. 82, p. 116-124 9 p.Research output: Contribution to journal › Article
16
Citations
(Scopus)
Hyperhomocysteinemia abrogates fasting-induced cardioprotection against ischemia/reperfusion by limiting bioavailability of hydrogen sulfide anions
Nakano, S., Ishii, I., Shinmura, K., Tamaki, K., Hishiki, T., Akahoshi, N., Ida, T., Nakanishi, T., Kamata, S., Kumagai, Y., Akaike, T., Fukuda, K., Sano, M. & Suematsu, M., 2015 Mar 6, (Accepted/In press) In : Journal of Molecular Medicine.Research output: Contribution to journal › Article
21
Citations
(Scopus)
Impacts of CD44 knockdown in cancer cells on tumor and host metabolic systems revealed by quantitative imaging mass spectrometry
Ohmura, M., Hishiki, T., Yamamoto, T., Nakanishi, T., Kubo, A., Tsuchihashi, K., Tamada, M., Toue, S., Kabe, Y., Saya, H. & Suematsu, M., 2015 Apr 30, In : Nitric Oxide - Biology and Chemistry. 46, p. 102-113 12 p.Research output: Contribution to journal › Article
14
Citations
(Scopus)
Inhibition of the oxygen sensor PHD2 in the liver improves survival in lactic acidosis by activating the Cori cycle
Suhara, T., Hishiki, T., Kasahara, M., Hayakawa, N., Oyaizu, T., Nakanishi, T., Kubo, A., Morisaki, H., Kaelin, W. G., Suematsu, M. & Minamishima, Y., 2015 Sep 15, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 37, p. 11642-11647 6 p.Research output: Contribution to journal › Article
20
Citations
(Scopus)
Involvement of the yciW gene in l-cysteine and l-methionine metabolism in Escherichia coli
Kawano, Y., Ohtsu, I., Tamakoshi, A., Shiroyama, M., Tsuruoka, A., Saiki, K., Takumi, K., Nonaka, G., Nakanishi, T., Hishiki, T., Suematsu, M. & Takagi, H., 2015 Mar 1, In : Journal of Bioscience and Bioengineering. 119, 3, p. 310-313 4 p.Research output: Contribution to journal › Article
14
Citations
(Scopus)
Therapeutic hypothermia achieves neuroprotection via a decrease in acetylcholine with a concurrent increase in carnitine in the neonatal hypoxia-ischemia
Takenouchi, T., Sugiura, Y., Morikawa, T., Nakanishi, T., Nagahata, Y., Sugioka, T., Honda, K., Kubo, A., Hishiki, T., Matsuura, T., Hoshino, T., Takahashi, T., Suematsu, M. & Kajimura, M., 2015 May 5, In : Journal of Cerebral Blood Flow and Metabolism. 35, 5, p. 794-805 12 p.Research output: Contribution to journal › Article
16
Citations
(Scopus)
2014
Large-area surface-enhanced raman spectroscopy imaging of brain ischemia by gold nanoparticles grown on random nanoarrays of transparent boehmite
Yamazoe, S., Naya, M., Shiota, M., Morikawa, T., Kubo, A., Tani, T., Hishiki, T., Horiuchi, T., Suematsu, M. & Kajimura, M., 2014 Jun 24, In : ACS Nano. 8, 6, p. 5622-5632 11 p.Research output: Contribution to journal › Article
43
Citations
(Scopus)
Neutral aminoaciduria in cystathionine β-synthase-deficient mice, an animal model of homocystinuria
Akahoshi, N., Kamata, S., Kubota, M., Hishiki, T., Nagahata, Y., Matsuura, T., Yamazaki, C., Yoshida, Y., Yamada, H., Ishizaki, Y., Suematsu, M., Kasahara, T. & Ishii, I., 2014 Jun 15, In : American Journal of Physiology - Renal Physiology. 306, 12, p. F1462-F1476Research output: Contribution to journal › Article
10
Citations
(Scopus)
Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway
Yamamoto, T., Takano, N., Ishiwata, K., Ohmura, M., Nagahata, Y., Matsuura, T., Kamata, A., Sakamoto, K., Nakanishi, T., Kubo, A., Hishiki, T. & Suematsu, M., 2014 Mar 17, In : Nature communications. 5, 3480.Research output: Contribution to journal › Article
108
Citations
(Scopus)
2013
A critical role of fatty acid binding protein 4 and 5 (FABP4/5) in the systemic response to fasting
Syamsunarno, M. R. A. A., Iso, T., Hanaoka, H., Yamaguchi, A., Obokata, M., Koitabashi, N., Goto, K., Hishiki, T., Nagahata, Y., Matsui, H., Sano, M., Kobayashi, M., Kikuchi, O., Sasaki, T., Maeda, K., Murakami, M., Kitamura, T., Suematsu, M., Tsushima, Y., Endo, K. & 2 others, , 2013 Nov 14, In : PloS one. 8, 11, e79386.Research output: Contribution to journal › Article
29
Citations
(Scopus)
Capillary endothelial fatty acid binding proteins 4 and 5 play a critical role in fatty acid uptake in heart and skeletal muscle
Iso, T., Maeda, K., Hanaoka, H., Suga, T., Goto, K., Syamsunarno, M. R. A. A., Hishiki, T., Nagahata, Y., Matsui, H., Arai, M., Yamaguchi, A., Abumrad, N. A., Sano, M., Suematsu, M., Endo, K., Hotamisligil, G. S. & Kurabayashi, M., 2013 Nov 1, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 33, 11, p. 2549-2557 9 p.Research output: Contribution to journal › Article
59
Citations
(Scopus)
Distinct metabolic flow enables large-scale purification of mouse and human pluripotent stem cell-derived cardiomyocytes
Tohyama, S., Hattori, F., Sano, M., Hishiki, T., Nagahata, Y., Matsuura, T., Hashimoto, H., Suzuki, T., Yamashita, H., Satoh, Y., Egashira, T., Seki, T., Muraoka, N., Yamakawa, H., Ohgino, Y., Tanaka, T., Yoichi, M., Yuasa, S., Murata, M., Suematsu, M. & 1 others, , 2013 Jan 3, In : Cell stem cell. 12, 1, p. 127-137 11 p.Research output: Contribution to journal › Article
360
Citations
(Scopus)
Energy management by enhanced glycolysis in G1-phase in human colon cancer cells in vitro and in vivo
Bao, Y., Mukai, K., Hishiki, T., Kubo, A., Ohmura, M., Sugiura, Y., Matsuura, T., Nagahata, Y., Hayakawa, N., Yamamoto, T., Fukuda, R., Saya, H., Suematsu, M. & Minamishima, Y., 2013 Sep 1, In : Molecular Cancer Research. 11, 9, p. 973-985 13 p.Research output: Contribution to journal › Article
38
Citations
(Scopus)
2012
Carbon monoxide: Impact on remethylation/transsulfuration metabolism and its pathophysiologic implications
Hishiki, T., Yamamoto, T., Morikawa, T., Kubo, A., Kajimura, M. & Suematsu, M., 2012 Mar 1, In : Journal of Molecular Medicine. 90, 3, p. 245-254 10 p.Research output: Contribution to journal › Review article
20
Citations
(Scopus)
Gas biology: Tiny molecules controlling metabolic systems
Kajimura, M., Nakanishi, T., Takenouchi, T., Morikawa, T., Hishiki, T., Yukutake, Y. & Suematsu, M., 2012 Nov 15, In : Respiratory Physiology and Neurobiology. 184, 2, p. 139-148 10 p.Research output: Contribution to journal › Review article
26
Citations
(Scopus)
Hypoxic regulation of the cerebral microcirculation is mediated by a carbon monoxide-sensitive hydrogen sulfide pathway
Morikawa, T., Kajimura, M., Nakamura, T., Hishiki, T., Nakanishi, T., Yukutake, Y., Nagahata, Y., Ishikawa, M., Hattori, K., Takenouchi, T., Takahashi, T., Ishii, I., Matsubara, K., Kabe, Y., Uchiyama, S., Nagata, E., Gadalla, M. M., Snyder, S. H. & Suematsu, M., 2012 Jan 24, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 4, p. 1293-1298 6 p.Research output: Contribution to journal › Article
150
Citations
(Scopus)
Methionine excess in diet induces acute lethal hepatitis in mice lacking cystathionine γ-lyase, an animal model of cystathioninuria
Yamada, H., Akahoshi, N., Kamata, S., Hagiya, Y., Hishiki, T., Nagahata, Y., Matsuura, T., Takano, N., Mori, M., Ishizaki, Y., Izumi, T., Kumagai, Y., Kasahara, T., Suematsu, M. & Ishii, I., 2012 May 1, In : Free Radical Biology and Medicine. 52, 9, p. 1716-1726 11 p.Research output: Contribution to journal › Article
48
Citations
(Scopus)
Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue
Imaizumi, Y., Okada, Y., Akamatsu, W., Koike, M., Kuzumaki, N., Hayakawa, H., Nihira, T., Kobayashi, T., Ohyama, M., Sato, S., Takanashi, M., Funayama, M., Hirayama, A., Soga, T., Hishiki, T., Suematsu, M., Yagi, T., Ito, D., Kosakai, A., Hayashi, K. & 10 others, , 2012, In : Molecular brain. 5, 1, 35.Research output: Contribution to journal › Article
218
Citations
(Scopus)
2011
Disruption of HIF-1α in hepatocytes impairs glucose metabolism in diet-induced obesity mice
Ochiai, D., Goda, N., Hishiki, T., Kanai, M., Senoo-Matsuda, N., Soga, T., Johnson, R. S., Yoshimura, Y. & Suematsu, M., 2011 Nov 25, In : Biochemical and Biophysical Research Communications. 415, 3, p. 445-449 5 p.Research output: Contribution to journal › Article
31
Citations
(Scopus)
Triacylglycerol/phospholipid molecular species profiling of fatty livers and regenerated non-fatty livers in cystathionine beta-synthase-deficient mice, an animal model for homocysteinemia/homocystinuria
Ikeda, K., Kubo, A., Akahoshi, N., Yamada, H., Miura, N., Hishiki, T., Nagahata, Y., Matsuura, T., Suematsu, M., Taguchi, R. & Ishii, I., 2011 Jun 1, In : Analytical and bioanalytical chemistry. 400, 7, p. 1853-1863 11 p.Research output: Contribution to journal › Article
17
Citations
(Scopus)
Use of serum and urine metabolome analysis for the detection of metabolic changes in patients with stage 1-2 chronic kidney disease
Hayashi, K., Sasamura, H., Hishiki, T., Suematsu, M., Ikeda, S., Soga, T. & Itoh, H., 2011 Jan 1, In : Nephro-Urology Monthly. 3, 3, p. 164-171 8 p.Research output: Contribution to journal › Article
20
Citations
(Scopus)
2010
4-Hydroxy-2-nonenal protects against cardiac ischemia-reperfusion injury via the Nrf2-dependent pathway
Zhang, Y., Sano, M., Shinmura, K., Tamaki, K., Katsumata, Y., Matsuhashi, T., Morizane, S., Ito, H., Hishiki, T., Endo, J., Zhou, H., Yuasa, S., Kaneda, R., Suematsu, M. & Fukuda, K., 2010 Oct 1, In : Journal of Molecular and Cellular Cardiology. 49, 4, p. 576-586 11 p.Research output: Contribution to journal › Article
94
Citations
(Scopus)
Hypotaurine is an energy-saving hepatoprotective compound against ischemia-reperfusion injury of the rat liver
Sakuragawa, T., Hishiki, T., Ueno, Y., Ikeda, S., Soga, T., Yachie-Kinoshita, A., Kajimura, M. & Suematsu, M., 2010 Mar, In : Journal of Clinical Biochemistry and Nutrition. 46, 2, p. 126-134 9 p.Research output: Contribution to journal › Article
24
Citations
(Scopus)
Paradoxical ATP elevation in ischemic penumbra revealed by quantitative imaging mass spectrometry
Hattori, K., Kajimura, M., Hishiki, T., Nakanishi, T., Kubo, A., Nagahata, Y., Ohmura, M., Yachie-Kinoshita, A., Matsuura, T., Morikawa, T., Nakamura, T., Setou, M. & Suematsu, M., 2010 Oct 15, In : Antioxidants and Redox Signaling. 13, 8, p. 1157-1167 11 p.Research output: Contribution to journal › Review article
71
Citations
(Scopus)
Phosphorescence-assisted microvascular O2 measurements reveal alterations of oxygen demand in human metastatic colon cancer in the liver of superimmunodeficient NOG mice
Handa, K., Ohmura, M., Nishime, C., Hishiki, T., Nagahata, Y., Kawai, K., Suemizu, H., Nakamura, M., Wakui, M., Kitagawa, Y., Suematsu, M. & Tsukada, K., 2010 Dec 1, Oxygen Transport to Tissue XXXI. Takahashi, E. & Bruley, D. (eds.). p. 423-429 7 p. (Advances in Experimental Medicine and Biology; vol. 662).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
8
Citations
(Scopus)
Reduced CD73 expression and its association with altered purine nucleotide metabolism in colorectal cancer cells robustly causing liver metastases
Matsuyama, M., Wakui, M., Monnai, M., Mizushima, T., Nishime, C., Kawai, K., Ohmura, M., Suemizu, H., Hishiki, T., Suematsu, M., Murata, M., Chijiwa, T., Furukawa, D., Ogoshi, K., Makuuchi, H. & Nakamura, M., 2010 May 1, In : Oncology Letters. 1, 3, p. 431-436 6 p.Research output: Contribution to journal › Article
4
Citations
(Scopus)
T-state stabilization of hemoglobin by nitric oxide to form α-nitrosyl heme causes constitutive release of ATP from human erythrocytes
Akatsu, T., Tsukada, K., Hishiki, T., Suga-Numa, K., Tanabe, M., Shimazu, M., Kitagawa, Y., Yachie-Kinoshita, A. & Suematsu, M., 2010 Dec 1, Oxygen Transport to Tissue XXXI. Takahashi, E. & Bruley, D. (eds.). p. 109-114 6 p. (Advances in Experimental Medicine and Biology; vol. 662).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
5
Citations
(Scopus)
2009
Cystathionine β-synthase as a carbon monoxide-sensitive regulator of bile excretion
Shintani, T., Iwabuchi, T., Soga, T., Kato, Y., Yamamoto, T., Takano, N., Hishiki, T., Ueno, Y., Ikeda, S., Sakuragawa, T., Ishikawa, K., Goda, N., Kitagawa, Y., Kajimura, M., Matsumoto, K. & Suematsu, M., 2009 Mar 9, In : Hepatology. 49, 1, p. 141-150 10 p.Research output: Contribution to journal › Article
82
Citations
(Scopus)
HIF-1α is necessary to support gluconeogenesis during liver regeneration
Tajima, T., Goda, N., Fujiki, N., Hishiki, T., Nishiyama, Y., Senoo-Matsuda, N., Shimazu, M., Soga, T., Yoshimura, Y., Johnson, R. S. & Suematsu, M., 2009 Oct 2, In : Biochemical and Biophysical Research Communications. 387, 4, p. 789-794 6 p.Research output: Contribution to journal › Article
43
Citations
(Scopus)
Metabolic remodeling induced by mitochondrial aldehyde stress stimulates tolerance to oxidative stress in the heart
Endo, J., Sano, M., Katayama, T., Hishiki, T., Shinmura, K., Morizane, S., Matsuhashi, T., Katsumata, Y., Zhang, Y., Ito, H., Nagahata, Y., Marchitti, S., Nishimaki, K., Wolf, A. M., Nakanishi, H., Hattori, F., Vasiliou, V., Adachi, T., Ohsawa, I., Taguchi, R. & 5 others, , 2009 Nov, In : Circulation research. 105, 11, p. 1118-1127 10 p.Research output: Contribution to journal › Article
97
Citations
(Scopus)
Mono-(2-ethylhexyl) phthalate targets glycogen debranching enzyme and affects glycogen metabolism in rat testis
Kuramori, C., Hase, Y., Hoshikawa, K., Watanabe, K., Nishi, T., Hishiki, T., Soga, T., Nashimoto, A., Kabe, Y., Yamaguchi, Y., Watanabe, H., Kataoka, K., Suematsu, M. & Handa, H., 2009 May 13, In : Toxicological Sciences. 109, 1, p. 143-151 9 p.Research output: Contribution to journal › Article
11
Citations
(Scopus)
2007
Roles of hemoglobin allostery in hypoxia-induced metabolic alterations in erythrocytes: Simulation and its verification by metabolome analysis
Kinoshita, A., Tsukada, K., Soga, T., Hishiki, T., Ueno, Y., Nakayama, Y., Tomita, M. & Suematsu, M., 2007 Apr 6, In : Journal of Biological Chemistry. 282, 14, p. 10731-10741 11 p.Research output: Contribution to journal › Article
72
Citations
(Scopus)
2004
Refolding processes of cytochrome P450cam from ferric and ferrous acid forms to the native conformation. Formations of folding intermediates with non-native heme coordination state
Egawa, T., Hishiki, T., Ichikawa, Y., Kanamori, Y., Shimada, H., Takahashi, S., Kitagawa, T. & Ishimura, Y., 2004 Jul 30, In : Journal of Biological Chemistry. 279, 31, p. 32008-32017 10 p.Research output: Contribution to journal › Article
7
Citations
(Scopus)
2003
Infrared Spectroscopic and Mutational Studies on Putidaredoxin-Induced Conformational Changes in Ferrous CO-P450cam
Nagano, S., Shimada, H., Tarumi, A., Hishiki, T., Kimata-Ariga, Y., Egawa, T., Suematsu, M., Park, S. Y., Adachi, S. I., Shiro, Y. & Ishimura, Y., 2003 Dec 16, In : Biochemistry. 42, 49, p. 14507-14514 8 p.Research output: Contribution to journal › Article
47
Citations
(Scopus)
2000
X-ray crystal structure and catalytic properties of Thr252Ile mutant of cytochrome P450cam: Roles of Thr252 and water in the active center
Hishiki, T., Shimada, H., Nagano, S., Egawa, T., Kanamori, Y., Makino, R., Park, S. Y., Adachi, S. I., Shiro, Y. & Ishimura, Y., 2000 Jan 1, In : Journal of biochemistry. 128, 6, p. 965-974 10 p.Research output: Contribution to journal › Article
49
Citations
(Scopus)
1999
Putidaredoxin-cytochrome P450(cam) interaction: Spin state of the heme iron modulates putidaredoxin structure
Shimada, H., Nagano, S., Ariga, Y., Unno, M., Egawa, T., Hishiki, T., Ishimura, Y., Masuya, F., Obata, T. & Hori, H., 1999 Apr 2, In : Journal of Biological Chemistry. 274, 14, p. 9363-9369 7 p.Research output: Contribution to journal › Article
38
Citations
(Scopus)