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Research Output 1999 2019

  • 6535 Citations
  • 30 h-Index
  • 84 Article
  • 6 Letter
  • 2 Chapter
  • 2 Review article
2019
11 Citations (Scopus)

APOE Alleles and Extreme Human Longevity

Sebastiani, P., Gurinovich, A., Nygaard, M., Sasaki, T., Sweigart, B., Bae, H., Andersen, S. L., Villa, F., Atzmon, G., Christensen, K., Arai, Y., Barzilai, N., Puca, A., Christiansen, L., Hirose, N. & Perls, T. T., 2019 Jan 1, In : The journals of gerontology. Series A, Biological sciences and medical sciences. 74, 1, p. 44-51 8 p.

Research output: Contribution to journalArticle

Alleles
Genotype
Population
New England
Retirement

Case of Conradi–Hünermann–Happle syndrome due to a nonsense mutation of c.245G>A (p.W82*)

Satake, M., Kudo, K., Sasaki, T., Furue, M. & Kubo, A., 2019 Jan 1, In : Journal of Dermatology.

Research output: Contribution to journalLetter

Chondrodysplasia Punctata
Nonsense Codon
2 Citations (Scopus)

Clonal Expansion of Second-Hit Cells with Somatic Recombinations or C>T Transitions Form Porokeratosis in MVD or MVK Mutant Heterozygotes

Kubo, A., Sasaki, T., Suzuki, H., Shiohama, A., Aoki, S., Sato, S., Fujita, H., Ono, N., Umegaki-Arao, N., Kawai, T., Nakabayashi, K., Hata, K., Yamada, D., Matsubara, Y., Kosaki, K. & Amagai, M., 2019 Dec, In : Journal of Investigative Dermatology. 139, 12, p. 2458-2466.e9

Research output: Contribution to journalArticle

Open Access
Porokeratosis
Heterozygote
Genetic Recombination
Skin
Genes

Genetic Protective Factors for Dementia Isolated by Centenarian Researches

Sasaki, T., Nishimoto, Y., Hirose, N. & Arai, Y., 2019 Oct 1, In : Brain and nerve = Shinkei kenkyu no shinpo. 71, 10, p. 1061-1070 10 p.

Research output: Contribution to journalReview article

Dementia
Maintenance
Research
Cognition
Protective Factors
1 Citation (Scopus)

Induced Pluripotent Stem Cells Reprogrammed with Three Inhibitors Show Accelerated Differentiation Potentials with High Levels of 2-Cell Stage Marker Expression

Nishihara, K., Shiga, T., Nakamura, E., Akiyama, T., Sasaki, T., Suzuki, S., Ko, M., Tada, N., Okano, H. & Akamatsu, W., 2019 Feb 12, In : Stem Cell Reports. 12, 2, p. 305-318 14 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Stem cells
Pluripotent Stem Cells
Fibroblast Growth Factor 4
Stem Cells

Novel gene mutations in Chédiak–Higashi syndrome with hyperpigmentation

Fukuchi, K., Tatsuno, K., Sakaguchi, K., Sano, S., Sasaki, T., Aoki, S., Kubo, A. & Tokura, Y., 2019 Jan 1, In : Journal of Dermatology.

Research output: Contribution to journalLetter

Chediak-Higashi Syndrome
Hyperpigmentation
Mutation
Genes

Recovery of FRI-5 carbapenemase at a Japanese hospital where FRI-4 carbapenemase was discovered

Uwamino, Y., Kubota, H., Sasaki, T., Kosaka, A., Furuhashi, M., Uno, S., Kudoh, J., Murata, M. & Hasegawa, N., 2019 Nov 1, In : The Journal of antimicrobial chemotherapy. 74, 11, p. 3390-3492 103 p.

Research output: Contribution to journalArticle

carbapenemase

Subclinical hypopigmentation of the skin and hair in a Japanese patient with Hermansky–Pudlak syndrome type 3

Saito, S., Tanaka, R., Sasaki, T., Aoki, S., Yasuhara, R., Nakayama, Y., Nagai, T., Sonobe, H., Ozawa, Y. & Kubo, A., 2019 Jan 1, (Accepted/In press) In : Journal of Dermatology.

Research output: Contribution to journalLetter

Hermanski-Pudlak Syndrome
Hypopigmentation
Hair
Skin

The desmosome is a mesoscale lipid raft-like membrane domain

Lewis, J. D., Caldara, A. L., Zimmer, S. E., Stahley, S. N., Seybold, A., Strong, N. L., Frangakis, A. S., Levental, I., Wahl, J. K., Mattheyses, A. L., Sasaki, T., Nakabayashi, K., Hata, K., Matsubara, Y., Ishida-Yamamoto, A., Amagai, M., Kubo, A. & Kowalczyk, A. P., 2019 Jun 1, In : Molecular biology of the cell. 30, 12, p. 1390-1405 16 p.

Research output: Contribution to journalArticle

Open Access
Desmogleins
Desmosomes
Cadherins
Lipids
Mutation
2018
3 Citations (Scopus)

A familial case of nail patella syndrome with a heterozygous in-frame indel mutation in the LIM domain of LMX1B

Mukai, M., Fujita, H., Umegaki, N., Sasaki, T., Yasuda-Sekiguchi, F., Isojima, T., Kitanaka, S., Amagai, M. & Kubo, A., 2018 Apr 1, In : Journal of Dermatological Science. 90, 1, p. 90-93 4 p.

Research output: Contribution to journalLetter

Nail-Patella Syndrome
Nails
Mutation
Haploinsufficiency
Assays
17 Citations (Scopus)

Deep whole-genome sequencing reveals recent selection signatures linked to evolution and disease risk of Japanese

Okada, Y., Momozawa, Y., Sakaue, S., Kanai, M., Ishigaki, K., Akiyama, M., Kishikawa, T., Arai, Y., Sasaki, T., Kosaki, K., Suematsu, M., Matsuda, K., Yamamoto, K., Kubo, M., Hirose, N. & Kamatani, Y., 2018 Dec 1, In : Nature Communications. 9, 1, 1631.

Research output: Contribution to journalArticle

sequencing
genome
Genes
Genetic Selection
signatures
4 Citations (Scopus)

HER2 heterogeneity is associated with poor survival in HER2-positive breast cancer

Hosonaga, M., Arima, Y., Sampetrean, O., Komura, D., Koya, I., Sasaki, T., Sato, E., Okano, H., Kudo, J., Ishikawa, S., Saya, H. & Ishikawa, T., 2018 Aug 1, In : International Journal of Molecular Sciences. 19, 8, 2158.

Research output: Contribution to journalArticle

breast
cancer
Breast Neoplasms
mice
RNA Sequence Analysis

Intragenic copy number variation within human epiplakin 1 (EPPK1) generates variation of molecular size of epiplakin

Ishikawa, K., Furuhashi, M., Sasaki, T., Kudo, J., Tsuchisaka, A., Hashimoto, T., Sasaki, T., Yoshioka, H., Eshima, N., Matsuda-Hirose, H., Sakai, T., Hatano, Y. & Fujiwara, S., 2018 Aug 1, In : Journal of Dermatological Science. 91, 2, p. 228-231 4 p.

Research output: Contribution to journalLetter

epiplakin

Junctional epidermolysis bullosa without pyloric atresia due to a homozygous missense mutation in ITGB4

Yoshida, K., Sadamoto, M., Sasaki, T., Kubo, A. & Ishiko, A., 2018 Jan 1, (Accepted/In press) In : Journal of Dermatology.

Research output: Contribution to journalArticle

Junctional Epidermolysis Bullosa
Missense Mutation
Pyloric Atresia
1 Citation (Scopus)

Linear keratinocytic epidermal nevi on trunk skin caused by a somatic FGFR2 p.C382R mutation

Tanaka, R., Umegaki, N., Sasaki, T., Aoki, S., Yoshida, K., Niizeki, H. & Kubo, A., 2018 Nov 1, In : Journal of Dermatology. 45, 11, p. e302-e303

Research output: Contribution to journalLetter

Skin
Mutation
Epidermal Nevus
2017
17 Citations (Scopus)

Association study of childhood food allergy with genome-wide association studies-discovered loci of atopic dermatitis and eosinophilic esophagitis

Hirota, T., Nakayama, T., Sato, S., Yanagida, N., Matsui, T., Sugiura, S., Takaoka, Y., Hizawa, N., Fujieda, S., Miyatake, A., Sasaki, T., Amagai, M., Doi, S., Ito, K., Sasaki, T. & Amagai, M., 2017, (Accepted/In press) In : Journal of Allergy and Clinical Immunology.

Research output: Contribution to journalArticle

2 Citations (Scopus)
Hypotrichosis
Hair
Mutation
Homozygote
Autosomal Recessive Woolly Hair
9 Citations (Scopus)

Induction of hair follicle dermal papilla cell properties in human induced pluripotent stem cell-derived multipotent LNGFR(+)THY-1(+) mesenchymal cells

Veraitch, O., Mabuchi, Y., Matsuzaki, Y., Sasaki, T., Okuno, H., Tsukashima, A., Amagai, M., Okano, H. & Ohyama, M., 2017 Feb 21, In : Scientific Reports. 7, 42777.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Hair Follicle
Skin
Hair
Keratinocytes
5 Citations (Scopus)

Inflammatory Linear Verrucous Epidermal Nevus with a Postzygotic GJA1 Mutation Is a Mosaic Erythrokeratodermia Variabilis et Progressiva

Umegaki, N., Sasaki, T., Fujita, H., Aoki, S., Kameyama, K., Amagai, M., Seishima, M. & Kubo, A., 2017 Apr 1, In : Journal of Investigative Dermatology. 137, 4, p. 967-970 4 p.

Research output: Contribution to journalArticle

Connexin 43
1 Citation (Scopus)

Novel KRT9 missense mutation in a Japanese case of epidermolytic palmoplantar keratoderma

Fukunaga, Y., Kubo, A., Sasaki, T., Tsuruta, D. & Fukai, K., 2017, (Accepted/In press) In : Journal of Dermatology.

Research output: Contribution to journalArticle

11 Citations (Scopus)

RNA Sequencing Analysis Reveals Interactions between Breast Cancer or Melanoma Cells and the Tissue Microenvironment during Brain Metastasis

Sato, R., Nakano, T., Hosonaga, M., Sampetrean, O., Harigai, R., Sasaki, T., Koya, I., Okano, H., Kudo, J., Saya, H. & Arima, Y., 2017, In : BioMed Research International. 2017, 8032910.

Research output: Contribution to journalArticle

RNA Sequence Analysis
Cellular Microenvironment
Melanoma
Brain
RNA
1 Citation (Scopus)

Somatic HRAS p.G12S mosaic mutation causes unilaterally distributed epidermal nevi, woolly hair and palmoplantar keratosis

Honda, A., Umegaki, N., Sasaki, T., Nakabayashi, K., Hata, K., Matsubara, Y., Tanikawa, A., Amagai, M. & Kubo, A., 2017, (Accepted/In press) In : Journal of Dermatology.

Research output: Contribution to journalArticle

2016
2 Citations (Scopus)

Case of dominant dystrophic epidermolysis bullosa with amniotic band syndrome

Sakiyama, T., Umegaki, N., Sasaki, T., Kosaki, K., Amagai, M. & Kubo, A., 2016, (Accepted/In press) In : Journal of Dermatology.

Research output: Contribution to journalArticle

Amniotic Band Syndrome
Collagen Type VII
Epidermolysis Bullosa Dystrophica
Genetic Testing
Missense Mutation
9 Citations (Scopus)
Japan
Demography
Tokyo
Gastrointestinal Diseases
Adiponectin
1 Citation (Scopus)

Distinct phenotype of epidermolysis bullosa simplex with infantile migratory circinate erythema due to frameshift mutations in the V2 domain of KRT5

Kumagai, Y., Umegaki, N., Sasaki, T., Nakamura, Y., Takahashi, H., Ashida, A., Tsunemi, Y., Kawashima, M., Shimizu, A., Ishiko, A., Nakamura, K., Tsuchihashi, H., Amagai, M. & Kubo, A., 2016, (Accepted/In press) In : Journal of the European Academy of Dermatology and Venereology.

Research output: Contribution to journalArticle

Frameshift Mutation
Phenotype
Epidermolysis Bullosa Simplex with Migratory Circinate Erythema
6 Citations (Scopus)

Identification and characterization of a recessive missense mutation p.P277L in SERPINB7 in nagashima-type palmoplantar keratosis

Shiohama, A., Sasaki, T., Sato, S., Sakabe, J. I., Ito, T., Isoda, H., Zenke, Y., Nakano, T., Maeda, T., Ishiko, A., Kabashima, K., Tokura, Y., Mitsuhashi, Y., Amagai, M. & Kubo, A., 2016 Jan 1, In : Journal of Investigative Dermatology. 136, 1, p. 325-328 4 p.

Research output: Contribution to journalArticle

Palmoplantar Keratoderma
Serpins
Inheritance Patterns
Mass Screening
Missense Mutation
33 Citations (Scopus)

Transepidermal water loss measurement during infancy can predict the subsequent development of atopic dermatitis regardless of filaggrin mutations

Horimukai, K., Morita, K., Narita, M., Kondo, M., Kabashima, S., Inoue, E., Sasaki, T., Niizeki, H., Saito, H., Matsumoto, K. & Ohya, Y., 2016 Jan 1, In : Allergology International. 65, 1, p. 103-108 6 p.

Research output: Contribution to journalArticle

Atopic Dermatitis
Mutation
Water
Forehead
Ovomucin
2015
2 Citations (Scopus)

Case of non-Herlitz junctional epidermolysis bullosa with COL17A1 mutation

Kasai, H., Sasaki, T., Matsuzaki, H., Yoshioka, T., Nagao, K., Amagai, M., Ishiko, A. & Kubo, A., 2015 Mar 1, In : Journal of Dermatology. 42, 3, p. 323-325 3 p.

Research output: Contribution to journalArticle

Non-Fibrillar Collagens
Junctional Epidermolysis Bullosa
Autoantigens
Mutation
1 Citation (Scopus)

Japanese recurrent mutation c.6216+5G>T in COL7A1 leads to a mild phenotype of dystrophic epidermolysis bullosa

Masunaga, T., Saito, M., Sasaki, T., Kubo, A., Amagai, M. & Ishiko, A., 2015 Dec 1, In : Journal of Dermatological Science. 80, 3, p. 220-223 4 p.

Research output: Contribution to journalArticle

Collagen Type VII
Epidermolysis Bullosa Dystrophica
Founder Effect
Japan
Alleles
83 Citations (Scopus)

Long-term safety issues of iPSC-based cell therapy in a spinal cord injury model: Oncogenic transformation with epithelial-mesenchymal transition

Nori, S., Okada, Y., Nishimura, S., Sasaki, T., Itakura, G., Kobayashi, Y., Renault-Mihara, F., Shimizu, A., Koya, I., Yoshida, R., Kudo, J., Koike, M., Uchiyama, Y., Ikeda, E., Toyama, Y., Nakamura, M. & Okano, H., 2015 Mar 10, In : Stem Cell Reports. 4, 3, p. 360-373 14 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Epithelial-Mesenchymal Transition
Cell- and Tissue-Based Therapy
Stem cells
Spinal Cord Injuries
9 Citations (Scopus)

Pathological characterization of pachydermia in pachydermoperiostosis

Tanese, K., Niizeki, H., Seki, A., Otsuka, A., Kabashima, K., Kosaki, K., Kuwahara, M., Miyakawa, S. I., Miyasaka, M., Matsuoka, K., Okuyama, T., Shiohama, A., Sasaki, T., Kudo, J., Amagai, M. & Ishiko, A., 2015 Jul 1, In : Journal of Dermatology. 42, 7, p. 710-714 5 p.

Research output: Contribution to journalArticle

Primary Hypertrophic Osteoarthropathy
Elastic Tissue
Mucins
Skin
Edema
14 Citations (Scopus)

Recurrent gastrointestinal perforation in a patient with Ehlers-Danlos syndrome due to tenascin-X deficiency

Sakiyama, T., Kubo, A., Sasaki, T., Yamada, T., Yabe, N., Matsumoto, K. I. & Futei, Y., 2015 May 1, In : Journal of Dermatology. 42, 5, p. 511-514 4 p.

Research output: Contribution to journalArticle

Exome
Ehlers-Danlos Syndrome
Genetic Heterogeneity
Nonsense Codon
tenascin X
111 Citations (Scopus)

YAP is essential for tissue tension to ensure vertebrate 3D body shape

Porazinski, S., Wang, H., Asaoka, Y., Behrndt, M., Miyamoto, T., Morita, H., Hata, S., Sasaki, T., Krens, S. F. G., Osada, Y., Asaka, S., Momoi, A., Linton, S., Miesfeld, J. B., Link, B. A., Senga, T., Castillo-Morales, A., Urrutia, A. O., Shimizu, N., Nagase, H. & 6 others, Matsuura, S., Bagby, S., Kondoh, H., Nishina, H., Heisenberg, C. P. & Furutani-Seiki, M., 2015 May 14, In : Nature. 521, 7551, p. 217-221 5 p.

Research output: Contribution to journalArticle

Vertebrates
Gravitation
Oryzias
Embryonic Structures
Actomyosin
2014
5 Citations (Scopus)

A Japanese case of Mal de Meleda with SLURP1 mutation

Sakabe, J. I., Kabashima-Kubo, R., Kubo, A., Sasaki, T. & Tokura, Y., 2014, In : Journal of Dermatology. 41, 8, p. 764-765 2 p.

Research output: Contribution to journalArticle

DNA Mutational Analysis
Ly Antigens
Palmoplantar Keratoderma
Urokinase-Type Plasminogen Activator
Pedigree
283 Citations (Scopus)

Application of moisturizer to neonates prevents development of atopic dermatitis

Horimukai, K., Morita, K., Narita, M., Kondo, M., Kitazawa, H., Nozaki, M., Shigematsu, Y., Yoshida, K., Niizeki, H., Motomura, K. I., Sago, H., Takimoto, T., Inoue, E., Kamemura, N., Kido, H., Hisatsune, J., Sugai, M., Murota, H., Katayama, I., Sasaki, T. & 6 others, Amagai, M., Morita, H., Matsuda, A., Matsumoto, K., Saito, H. & Ohya, Y., 2014 Oct 1, In : Journal of Allergy and Clinical Immunology. 134, 4, p. 824-830.e6

Research output: Contribution to journalArticle

Atopic Dermatitis
Newborn Infant
Eczema
Allergens
Immunoglobulin E
21 Citations (Scopus)

Filaggrin loss-of-function mutations are not a predisposing factor for atopic dermatitis in an Ishigaki Island under subtropical climate

Sasaki, T., Furusyo, N., Shiohama, A., Takeuchi, S., Nakahara, T., Uchi, H., Hirota, T., Tamari, M., Shimizu, N., Ebihara, T., Amagai, M., Furue, M., Hayashi, J. & Kudo, J., 2014, In : Journal of Dermatological Science. 76, 1, p. 10-15 6 p.

Research output: Contribution to journalArticle

Atopic Dermatitis
Climate
Islands
Causality
Mutation
13 Citations (Scopus)

Global gene expression analysis following spinal cord injury in non-human primates

Nishimura, S., Sasaki, T., Shimizu, A., Yoshida, K., Iwai, H., Koya, I., Kobayashi, Y., Itakura, G., Shibata, S., Ebise, H., Horiuchi, K., Kudo, J., Toyama, Y., Anderson, A. J., Okano, H. & Nakamura, M., 2014, In : Experimental Neurology. 261, p. 171-179 9 p.

Research output: Contribution to journalArticle

Spinal Cord Injuries
Primates
Gene Expression
Callithrix
Rodentia
1 Citation (Scopus)

Mouse models for spontaneous dermatitis due to impaired skin barrier formation

Sasaki, T., Shiohama, A. & Amagai, M., 2014, In : Japanese Journal of Clinical Immunology. 37, 3, p. 160-165 6 p.

Research output: Contribution to journalArticle

Dermatitis
Skin
Tail
Nonsense Codon
Mutation
17 Citations (Scopus)

The complete type of pachydermoperiostosis: A novel nonsense mutation p.E141* of the SLCO2A1 gene

Niizeki, H., Shiohama, A., Sasaki, T., Seki, A., Kabashima, K., Otsuka, A., Kosaki, K., Ogo, A., Yamada, T., Miyasaka, M., Matsuoka, K., Hirakiyama, A., Okuyama, T., Matsuda, M., Nakabayashi, K., Tanese, K., Ishiko, A., Amagai, M. & Kudo, J., 2014, In : Journal of Dermatological Science. 75, 3, p. 193-195 3 p.

Research output: Contribution to journalArticle

Hydroxyprostaglandin Dehydrogenases
Organic Anion Transporters
Dinoprostone
Introns
Exons
15 Citations (Scopus)

The novel SLCO2A1 heterozygous missense mutation p.E427K and nonsense mutation p.R603* in a female patient with pachydermoperiostosis with an atypical phenotype

Niizeki, H., Shiohama, A., Sasaki, T., Seki, A., Kabashima, K., Otsuka, A., Takeshita, M., Hirakiyama, A., Okuyama, T., Tanese, K., Ishiko, A., Amagai, M. & Kudo, J., 2014, In : British Journal of Dermatology. 170, 5, p. 1187-1189 3 p.

Research output: Contribution to journalArticle

Primary Hypertrophic Osteoarthropathy
Organic Anion Transporters
Nonsense Codon
Missense Mutation
Heterozygote
2013
62 Citations (Scopus)

A homozygous nonsense mutation in the gene for Tmem79, a component for the lamellar granule secretory system, produces spontaneous eczema in an experimental model of atopic dermatitis

Sasaki, T., Shiohama, A., Kubo, A., Kawasaki, H., Ishida-Yamamoto, A., Yamada, T., Hachiya, T., Shimizu, A., Okano, H., Kudo, J. & Amagai, M., 2013 Nov, In : Journal of Allergy and Clinical Immunology. 132, 5

Research output: Contribution to journalArticle

Nonsense Codon
Eczema
Secretory Vesicles
Atopic Dermatitis
Theoretical Models
9 Citations (Scopus)

Characterization of canine filaggrin: Gene structure and protein expression in dog skin

Kanda, S., Sasaki, T., Shiohama, A., Nishifuji, K., Amagai, M., Iwasaki, T. & Kudo, J., 2013 Feb, In : Veterinary Dermatology. 24, 1

Research output: Contribution to journalArticle

skin (animal)
Canidae
protein synthesis
Dogs
Skin
4 Citations (Scopus)

Dpysl4 is involved in tooth germ morphogenesis through growth regulation, polarization and differentiation of dental epithelial cells

Yasukawa, M., Ishida, K., Yuge, Y., Hanaoka, M., Minami, Y., Ogawa, M., Sasaki, T., Saito, M. & Tsuji, T., 2013 Apr 26, In : International Journal of Biological Sciences. 9, 4, p. 382-390 9 p.

Research output: Contribution to journalArticle

Tooth Germ
enamel
morphogenesis
Morphogenesis
tooth
33 Citations (Scopus)

Human induced pluripotent stem cell-derived ectodermal precursor cells contribute to hair follicle morphogenesis in vivo

Veraitch, O., Kobayashi, T., Imaizumi, Y., Akamatsu, W., Sasaki, T., Yamanaka, S., Amagai, M., Okano, H. & Ohyama, M., 2013 Jun, In : Journal of Investigative Dermatology. 133, 6, p. 1479-1488 10 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Hair Follicle
Stem cells
Morphogenesis
Cells
53 Citations (Scopus)

Mutations in SERPINB7, encoding a member of the serine protease inhibitor superfamily, cause nagashima-type palmoplantar keratosis

Kubo, A., Shiohama, A., Sasaki, T., Nakabayashi, K., Kawasaki, H., Atsugi, T., Sato, S., Shimizu, A., Mikami, S., Tanizaki, H., Uchiyama, M., Maeda, T., Taisuke, I., Sakabe, J. I., Heike, T., Okuyama, T., Kosaki, R., Kosaki, K., Kudo, J., Hata, K. & 7 others, Umezawa, A., Tokura, Y., Ishiko, A., Niizeki, H., Kabashima, K., Mitsuhashi, Y. & Amagai, M., 2013 Nov 7, In : American Journal of Human Genetics. 93, 5, p. 945-956 12 p.

Research output: Contribution to journalArticle

Palmoplantar Keratoderma
Serine Proteinase Inhibitors
Mutation
Cornea
Peptide Hydrolases
2012
182 Citations (Scopus)

Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population

Hirota, T., Takahashi, A., Kubo, M., Tsunoda, T., Tomita, K., Sakashita, M., Yamada, T., Fujieda, S., Tanaka, S., Doi, S., Miyatake, A., Enomoto, T., Nishiyama, C., Nakano, N., Maeda, K., Okumura, K., Ogawa, H., Ikeda, S., Noguchi, E., Sakamoto, T. & 10 others, Hizawa, N., Ebe, K., Saeki, H., Sasaki, T., Ebihara, T., Amagai, M., Takeuchi, S., Furue, M., Nakamura, Y. & Tamari, M., 2012 Nov, In : Nature Genetics. 44, 11, p. 1222-1226 5 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Atopic Dermatitis
Population
Interleukin-13
Validation Studies
51 Citations (Scopus)

Identification of mutations in the prostaglandin transporter gene SLCO2A1 and its phenotype-genotype correlation in Japanese patients with pachydermoperiostosis

Sasaki, T., Niizeki, H., Shimizu, A., Shiohama, A., Hirakiyama, A., Okuyama, T., Seki, A., Kabashima, K., Otsuka, A., Ishiko, A., Tanese, K., Miyakawa, S. I., Sakabe, J. I., Kuwahara, M., Amagai, M., Okano, H., Suematsu, M. & Kudo, J., 2012 Oct, In : Journal of Dermatological Science. 68, 1, p. 36-44 9 p.

Research output: Contribution to journalArticle

Primary Hypertrophic Osteoarthropathy
Genetic Association Studies
Prostaglandins
Genes
Mutation
53 Citations (Scopus)

Restoration of the intrinsic properties of human dermal papilla in vitro

Ohyama, M., Kobayashi, T., Sasaki, T., Shimizu, A. & Amagai, M., 2012 Sep 1, In : Journal of Cell Science. 125, 17, p. 4114-4125 12 p.

Research output: Contribution to journalArticle

Skin
Hair Follicle
In Vitro Techniques
Genes
Bioengineering
2011
18 Citations (Scopus)

Loss-of-function mutations within the filaggrin gene and atopic dermatitis

Kawasaki, H., Kubo, A., Sasaki, T. & Amagai, M., 2011 May 9, Pathogenesis and Management of Atopic Dermatitis. S. Karger AG, Vol. 41. p. 35-46 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Atopic Dermatitis
Mutation
Genes
Skin
Cornea
7 Citations (Scopus)

Transgenic rescue of desmoglein 3 null mice with desmoglein 1 to develop a syngeneic mouse model for pemphigus vulgaris

Hata, T., Nishifuji, K., Shimoda, K., Sasaki, T., Yamada, T., Nishikawa, T., Koyasu, S. & Amagai, M., 2011 Jul, In : Journal of Dermatological Science. 63, 1, p. 33-39 7 p.

Research output: Contribution to journalArticle

Desmoglein 3
Desmoglein 1
Pemphigus
Keratin-5
Histology