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Research Output 2005 2020

  • 795 Citations
  • 16 h-Index
  • 40 Article
  • 4 Chapter
  • 1 Review article
2020

Immune-resistant mechanisms in cancer immunotherapy

Kawakami, Y., Ohta, S., Sayem, M. A., Tsukamoto, N. & Yaguchi, T., 2020 Jan 1, (Accepted/In press) In : International Journal of Clinical Oncology.

Research output: Contribution to journalReview article

Immunotherapy
Neoplasms
T-Lymphocytes
Antibodies
Immunosuppressive Agents

NUAK2 localization in normal skin and its expression in a variety of skin tumors with YAP

Al-Busani, H., Al-Sobaihi, S., Nojima, K., Tanemura, A., Yaguchi, T., Kawakami, Y., Matsumura, H., Nishimura, E. K., Yokozeki, H. & Namiki, T., 2020 Feb, In : Journal of Dermatological Science. 97, 2, p. 143-151 9 p.

Research output: Contribution to journalArticle

Bowen's Disease
Tumors
Skin
Extramammary Paget's Disease
Squamous Cell Carcinoma
2019
74 Citations (Scopus)

A defined commensal consortium elicits CD8 T cells and anti-cancer immunity

Tanoue, T., Morita, S., Plichta, D. R., Skelly, A. N., Suda, W., Sugiura, Y., Narushima, S., Vlamakis, H., Motoo, I., Sugita, K., Shiota, A., Takeshita, K., Yasuma-Mitobe, K., Riethmacher, D., Kaisho, T., Norman, J. M., Mucida, D., Suematsu, M., Yaguchi, T., Bucci, V. & 8 others, Inoue, T., Kawakami, Y., Olle, B., Roberts, B., Hattori, M., Xavier, R. J., Atarashi, K. & Honda, K., 2019 Jan 31, In : Nature. 565, 7741, p. 600-605 6 p.

Research output: Contribution to journalArticle

Immunity
T-Lymphocytes
Listeriosis
Histocompatibility
Microbiota
2 Citations (Scopus)

Analysis of the Tumor Reactivity of Tumor-Infiltrating Lymphocytes in a Metastatic Melanoma Lesion that Lost Major Histocompatibility Complex Class I Expression after Anti–PD-1 Therapy

Inozume, T., Yaguchi, T., Ariyasu, R., Togashi, Y., Ohnuma, T., Honobe, A., Nishikawa, H., Kawakami, Y. & Kawamura, T., 2019 Jan 1, In : Journal of Investigative Dermatology.

Research output: Contribution to journalArticle

Tumor-Infiltrating Lymphocytes
Lymphocytes
Major Histocompatibility Complex
Tumors
Melanoma

Transcription factor homeobox D9 is involved in the malignant phenotype of cervical cancer through direct binding to the human papillomavirus oncogene promoter

Hirao, N., Iwata, T., Tanaka, K., Nishio, H., Nakamura, M., Morisada, T., Morii, K., Maruyama, N., Katoh, Y., Yaguchi, T., Ota, S., Kukimoto, I., Aoki, D. & Kawakami, Y., 2019 Jan 1, (Accepted/In press) In : Gynecologic Oncology.

Research output: Contribution to journalArticle

Homeobox Genes
Oncogenes
Uterine Cervical Neoplasms
Transcription Factors
Phenotype
2018
4 Citations (Scopus)

Human PBMC-transferred murine MHC class I/II-deficient NOG mice enable long-term evaluation of human immune responses

Yaguchi, T., Kobayashi, A., Inozume, T., Morii, K., Nagumo, H., Nishio, H., Iwata, T., Ka, Y., Katano, I., Ito, R., Ito, M. & Kawakami, Y., 2018 Nov 1, In : Cellular and Molecular Immunology. 15, 11, p. 953-962 10 p.

Research output: Contribution to journalArticle

Blood Cells
T-Lymphocytes
Graft vs Host Disease
Cell- and Tissue-Based Therapy
Melanoma
10 Citations (Scopus)

Involvement of local renin-angiotensin system in immunosuppression of tumor microenvironment

Nakamura, K., Yaguchi, T., Ohmura, G., Kobayashi, A., Kawamura, N., Iwata, T., Kiniwa, Y., Okuyama, R. & Kawakami, Y., 2018 Jan 1, In : Cancer Science. 109, 1, p. 54-64 11 p.

Research output: Contribution to journalArticle

Tumor Microenvironment
Angiotensin Receptor Antagonists
Immunosuppressive Agents
Renin-Angiotensin System
Immunosuppression
5 Citations (Scopus)

Tumor associated macrophages support the growth of FGF9-induced lung adenocarcinoma by multiple mechanisms

Hegab, A. E., Ozaki, M., Kagawa, S., Hamamoto, J., Yasuda, H., Naoki, K., Soejima, K., Yin, Y., Kinoshita, T., Yaguchi, T., Kawakami, Y., Ornitz, D. M. & Betsuyaku, T., 2018 May 1, In : Lung Cancer. 119, p. 25-35 11 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor 9
Macrophages
Growth
Neoplasms
Adenocarcinoma of lung
2017
15 Citations (Scopus)

Determination of poor prognostic immune features of tumour microenvironment in non-smoking patients with lung adenocarcinoma

Kinoshita, T., Kudo-Saito, C., Muramatsu, R., Fujita, T., Saito, M., Nagumo, H., Sakurai, T., Noji, S., Takahata, E., Yaguchi, T., Tsukamoto, N., Hayashi, Y., Kaseda, K., Kamiyama, I., Ohtsuka, T., Tomizawa, K., Shimoji, M., Mitsudomi, T., Asamura, H. & Kawakami, Y., 2017 Nov 1, In : European Journal of Cancer. 86, p. 15-27 13 p.

Research output: Contribution to journalArticle

Tumor Microenvironment
T-Lymphocytes
Adenocarcinoma
Non-Small Cell Lung Carcinoma
Immunosuppressive Agents
2 Citations (Scopus)

Inter-patient and intra-tumor heterogeneity in the sensitivity to tumor-targeted immunity in colorectal cancer

Miyauchi, T., Yaguchi, T. & Kawakami, Y., 2017, In : Japanese Journal of Clinical Immunology. 40, 1, p. 54-59 6 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Immunity
Microsatellite Repeats
Microsatellite Instability
Neoplasms
4 Citations (Scopus)

Prospects for personalized combination immunotherapy for solid tumors based on adoptive cell therapies and immune checkpoint blockade therapies

Kato, D., Yaguchi, T., Iwata, T., Morii, K., Nakagawa, T., Nishimura, R. & Kawakami, Y., 2017, In : Japanese Journal of Clinical Immunology. 40, 1, p. 68-77 10 p.

Research output: Contribution to journalArticle

Cell- and Tissue-Based Therapy
Immunotherapy
Neoplasms
T-Lymphocytes
Therapeutics
2016
14 Citations (Scopus)

Cancer-induced heterogeneous immunosuppressive tumor microenvironments and their personalized modulation

Yaguchi, T. & Kawakami, Y., 2016, In : International Immunology. 28, 8, p. 393-399 7 p.

Research output: Contribution to journalArticle

Tumor Microenvironment
Immunosuppressive Agents
Neoplasms
Immunotherapy
Immunosuppression
11 Citations (Scopus)

CHD7 promotes proliferation of neural stem cells mediated by MIF

Ota, S., Yaguchi, T., Okuno, H., Chneiweiss, H., Kawakami, Y. & Okano, H., 2016 Dec 13, In : Molecular Brain. 9, 1, p. 1-12 12 p.

Research output: Contribution to journalArticle

Neural Stem Cells
DNA-Binding Proteins
Cell Movement
Stem Cells
Chromatin
49 Citations (Scopus)

Melanoma cells control antimelanoma CTL responses via interaction between TIGIT and CD155 in the effector phase

Inozume, T., Yaguchi, T., Furuta, J., Harada, K., Kawakami, Y. & Shimada, S., 2016 Jan 1, In : Journal of Investigative Dermatology. 136, 1, p. 255-263 9 p.

Research output: Contribution to journalArticle

T-cells
Melanoma
Cytotoxic T-Lymphocytes
T-Lymphocytes
Tumors
14 Citations (Scopus)

MHC-compatible bone marrow stromal/stem cells trigger fibrosis by activating host T cells in a scleroderma mouse model

Ogawa, Y., Morikawa, S., Okano, H., Mabuchi, Y., Suzuki, S., Yaguchi, T., Sato, Y., Mukai, S., Yaguchi, S., Inaba, T., Okamoto, S., Kawakami, Y., Tsubota, K., Matsuzaki, Y. & Shimmura, S., 2016 Jan 26, In : eLife. 5, JANUARY2016, e09394.

Research output: Contribution to journalArticle

T-cells
Stem cells
Mesenchymal Stromal Cells
Bone
Fibrosis
21 Citations (Scopus)

MIF maintains the tumorigenic capacity of brain tumor-initiating cells by directly inhibiting p53

Fukaya, R., Ota, S., Yaguchi, T., Matsuzaki, Y., Sugihara, E., Okano, H., Saya, H., Kawakami, Y., Kawase, T., Yoshida, K. & Toda, M., 2016 May 1, In : Cancer Research. 76, 9, p. 2813-2823 11 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Brain Neoplasms
Cell Line
Macrophage Migration-Inhibitory Factors
Heterografts

Personalized cancer immunotherapy: Immune biomarkers and combination immunotherapy

Kawakami, Y., Popivanova, B., Nuchsupha, S., Hayakawa, T., Nakamura, K., Nagumo, H., Katano, I., Kinoshita, T., Tsubota, K., Kamijuku, H., Kawamura, N., Miyazaki, J., Satomi, R., Sugiyama, J., Nishio, H., Noji, S., Kudo-Saito, C., Tsukamoto, N., Sakurai, T., Fujita, T. & 1 others, Yaguchi, T., 2016 Feb 22, Immunotherapy of Cancer: An Innovative Treatment Comes of Age. Springer Japan, p. 349-358 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Immunotherapy
Biomarkers
Neoplasms
T-Lymphocytes
Mutation
49 Citations (Scopus)

Prognostic value of tumor-infiltrating lymphocytes differs depending on histological type and smoking habit in completely resected non-small-cell lung cancer

Kinoshita, T., Muramatsu, R., Fujita, T., Nagumo, H., Sakurai, T., Noji, S., Takahata, E., Yaguchi, T., Tsukamoto, N., Kudo-Saito, C., Hayashi, Y., Kamiyama, I., Ohtsuka, T., Asamura, H. & Kawakami, Y., 2016 Nov 1, In : Annals of oncology : official journal of the European Society for Medical Oncology. 27, 11, p. 2117-2123 7 p.

Research output: Contribution to journalArticle

Tumor-Infiltrating Lymphocytes
Non-Small Cell Lung Carcinoma
Habits
Smoking
Survival
2015
17 Citations (Scopus)

Aberrant myosin 1b expression promotes cell migration and lymph node metastasis of HNSCC

Ohmura, G., Tsujikawa, T., Yaguchi, T., Kawamura, N., Mikami, S., Sugiyama, J., Nakamura, K., Kobayashi, A., Iwata, T., Nakano, H., Shimada, T., Hisa, Y. & Kawakami, Y., 2015 Apr 1, In : Molecular Cancer Research. 13, 4, p. 721-731 11 p.

Research output: Contribution to journalArticle

Myosins
Cell Movement
Lymph Nodes
Neoplasm Metastasis
Cell Surface Extensions
13 Citations (Scopus)

Cytokine profile in cervical mucosa of Japanese patients with cervical intraepithelial neoplasia

Iwata, T., Fujii, T., Morii, K., Saito, M., Sugiyama, J., Nishio, H., Morisada, T., Tanaka, K., Yaguchi, T., Kawakami, Y. & Aoki, D., 2015 Feb 1, In : International Journal of Clinical Oncology. 20, 1, p. 126-133 8 p.

Research output: Contribution to journalArticle

Cervical Intraepithelial Neoplasia
Mucous Membrane
Interleukin-8
Interleukin-1
Cytokines
1 Citation (Scopus)

Development of personalized combination cancer immunotherapy based on the patients’ immune status

Kawakami, Y., Qian, L., Kawamura, N., Miyazaki, J., Nagumo, H., Tsubota, K., Kinoshita, T., Nakamua, K., Ohmura, G., Satomi, R., Sugiyama, J., Nishio, H., Hayakawa, T., Popivanova, B., Nuchsupha, S., Hsin-Ju Liu, T., Kamijuku, H., Kudo-Saito, C., Tsukamoto, N., Sakurai, T. & 2 others, Fujita, T. & Yaguchi, T., 2015 Jan 1, Inflammation and Immunity in Cancer. Springer Japan, p. 255-266 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Immunotherapy
Neoplasms
T-Lymphocytes
Biomarkers
Immunosuppressive Agents
12 Citations (Scopus)

NUAK2 amplification coupled with PTEN deficiency promotes melanoma development via CDK Activation

Namiki, T., Yaguchi, T., Nakamura, K., Valencia, J. C., Coelho, S. G., Yin, L., Kawaguchi, M., Vieira, W. D., Kaneko, Y., Tanemura, A., Katayama, I., Yokozeki, H., Kawakami, Y. & Hearing, V. J., 2015 Jul 1, In : Cancer Research. 75, 13, p. 2708-2715 8 p.

Research output: Contribution to journalArticle

Melanoma
Phosphatidylinositol 3-Kinases
Growth
S Phase
Therapeutics
6 Citations (Scopus)

Synergistic antiproliferative effect of imatinib and adriamycin in platelet-derived growth factor receptor-expressing osteosarcoma cells

Yamaguchi, S. I., Ueki, A., Sugihara, E., Onishi, N., Yaguchi, T., Kawakami, Y., Horiuchi, K., Morioka, H., Matsumoto, M., Nakamura, M., Muto, A., Toyama, Y., Saya, H. & Shimizu, T., 2015 Jul 1, In : Cancer Science. 106, 7, p. 875-882 8 p.

Research output: Contribution to journalArticle

Platelet-Derived Growth Factor Receptors
Osteosarcoma
Doxorubicin
Neoplasms
Phosphatidylinositol 3-Kinase
2014
36 Citations (Scopus)

Immunosuppression through constitutively activated NF-κB signalling in human ovarian cancer and its reversal by an NF-κB inhibitor

Nishio, H., Yaguchi, T., Sugiyama, J., Sumimoto, H., Umezawa, K., Iwata, T., Susumu, N., Fujii, T., Kawamura, N., Kobayashi, A., Park, J., Aoki, D. & Kawakami, Y., 2014 Jun 10, In : British Journal of Cancer. 110, 12, p. 2965-2974 10 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Immunosuppression
Interleukin-8
Arginase
Interleukin-6
1 Citation (Scopus)

Intratumoral Injection of BCG-CWS-pretreated dendritic cells following tumor cryoablation

Kawamura, N., Udagawa, M., Fujita, T., Sakurai, T., Yaguchi, T. & Kawakami, Y., 2014, In : Methods in Molecular Biology. 1139, p. 145-153 9 p.

Research output: Contribution to journalArticle

Cryosurgery
Mycobacterium bovis
Dendritic Cells
Injections
Neoplasms
3 Citations (Scopus)

Roles of signaling pathways in cancer cells and immune cells in generation of immunosuppressive tumor-associated microenvironments

Kawakami, Y., Yaguchi, T., Sumimoto, H., Kudo-Saito, C., Tsukamoto, N., Iwata-Kajihara, T., Nakamura, S., Nishio, H., Satomi, R., Kobayashi, A., Tanaka, M., Park, J. H., Kamijuku, H., Tsujikawa, T. & Kawamura, N., 2014 Jan 1, The Tumor Immunoenvironment. Springer Netherlands, p. 307-323 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Tumor Microenvironment
Immunosuppressive Agents
Neoplasms
Cytokines
Catenins
15 Citations (Scopus)

Significant roles of the (pro)renin receptor in integrity of vascular smooth muscle cells

Kurauchi-Mito, A., Ichihara, A., Bokuda, K., Sakoda, M., Kinouchi, K., Yaguchi, T., Yamada, T., Sun-Wada, G. H., Wada, Y. & Itoh, H., 2014 Sep 11, In : Hypertension Research. 37, 9, p. 830-835 6 p.

Research output: Contribution to journalArticle

Vascular Smooth Muscle
Renin
Smooth Muscle Myocytes
Vacuolar Proton-Translocating ATPases
Blood Vessels
19 Citations (Scopus)

TGF-β1 in tumor microenvironments induces immunosuppression in the tumors and sentinel lymph nodes and promotes tumor progression

Nakamura, S., Yaguchi, T., Kawamura, N., Kobayashi, A., Sakurai, T., Higuchi, H., Takaishi, H., Hibi, T. & Kawakami, Y., 2014 Feb, In : Journal of Immunotherapy. 37, 2, p. 63-72 10 p.

Research output: Contribution to journalArticle

Tumor Microenvironment
Immunosuppression
Immunosuppressive Agents
T-Lymphocytes
Neoplasms
2013
29 Citations (Scopus)

Angiotensin II Type 1 Receptor Antagonist Attenuates Lacrimal Gland, Lung, and Liver Fibrosis in a Murine Model of Chronic Graft-Versus-Host Disease

Yaguchi, S., Ogawa, Y., Shimmura, S., Kawakita, T., Hatou, S., Satofuka, S., Nakamura, S., Imada, T., Miyashita, H., Yoshida, S., Yaguchi, T., Ozawa, Y., Mori, T., Okamoto, S., Kawakami, Y., Ishida, S. & Tsubota, K., 2013 Jun 6, In : PLoS One. 8, 6, e64724.

Research output: Contribution to journalArticle

lacrimal apparatus
Angiotensin II Type 1 Receptor Blockers
Lacrimal Apparatus
liver cirrhosis
angiotensin II
39 Citations (Scopus)

Autocrine and paracrine loops between cancer cells and macrophages promote lymph node metastasis via CCR4/CCL22 in head and neck squamous cell carcinoma

Tsujikawa, T., Yaguchi, T., Ohmura, G., Ota, S., Kobayashi, A., Kawamura, N., Fujita, T., Nakano, H., Shimada, T., Takahashi, T., Nakao, R., Yanagisawa, A., Hisa, Y. & Kawakami, Y., 2013 Jun 15, In : International Journal of Cancer. 132, 12, p. 2755-2766 12 p.

Research output: Contribution to journalArticle

Lymph Nodes
Macrophages
Neoplasm Metastasis
Neoplasms
Tongue Neoplasms
16 Citations (Scopus)

Cancer-induced immunosuppressive cascades and their reversal by molecular-targeted therapy

Kawakami, Y., Yaguchi, T., Sumimoto, H., Kudo-Saito, C., Tsukamoto, N., Iwata-Kajihara, T., Nakamura, S., Nishio, H., Satomi, R., Kobayashi, A., Tanaka, M., Park, J. H., Kamijuku, H., Tsujikawa, T. & Kawamura, N., 2013 May, In : Annals of the New York Academy of Sciences. 1284, 1, p. 80-86 7 p.

Research output: Contribution to journalArticle

Molecular Targeted Therapy
Immunosuppressive Agents
Tumors
T-cells
Infiltration
17 Citations (Scopus)

Improvement of cancer immunotherapy by combining molecular targeted therapy

Kawakami, Y., Yaguchi, T., Sumimoto, H., Kudo-Saito, C., Iwata-Kajihara, T., Nakamura, S., Tsujikawa, T., Park, J. H., Popivanova, B. K., Miyazaki, J. & Kawamura, N., 2013, In : Frontiers in Oncology. 3 MAY, Article 136.

Research output: Contribution to journalArticle

Molecular Targeted Therapy
Immunotherapy
Immunosuppressive Agents
Neoplasms
Catenins
2012
19 Citations (Scopus)

Fibroblast growth factor-2 is an important factor that maintains cellular immaturity and contributes to aggressiveness of osteosarcoma

Shimizu, T., Ishikawa, T., Iwai, S., Ueki, A., Sugihara, E., Onishi, N., Kuninaka, S., Miyamoto, T., Toyama, Y., Ijiri, H., Mori, H., Matsuzaki, Y., Yaguchi, T., Nishio, H., Kawakami, Y., Ikeda, Y. & Saya, H., 2012 Mar, In : Molecular Cancer Research. 10, 3, p. 454-468 15 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor 2
Osteosarcoma
Osteogenesis
Leukemia Inhibitory Factor
Neoplasms

Human tumor antigens recognized by T cells and their implications for cancer immunotherapy

Ueda, R., Yaguchi, T. & Kawakami, Y., 2012 Jan 1, Innate Immune Regulation and Cancer Immunotherapy. Springer New York, p. 335-345 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Neoplasm Antigens
Immunotherapy
T-Lymphocytes
Neoplasms
Melanoma
62 Citations (Scopus)

Immune suppression and resistance mediated by constitutive activation of Wnt/-β-catenin signaling in human melanoma cells

Yaguchi, T., Goto, Y., Kido, K., Mochimaru, H., Sakurai, T., Tsukamoto, N., Kudo-Saito, C., Fujita, T., Sumimoto, H. & Kawakami, Y., 2012 Sep 1, In : Journal of Immunology. 189, 5, p. 2110-2117 8 p.

Research output: Contribution to journalArticle

Catenins
Melanoma
Dendritic Cells
Interleukin-10
Wnt Signaling Pathway
2011
69 Citations (Scopus)

The mechanisms of cancer immunoescape and development of overcoming strategies

Yaguchi, T., Sumimoto, H., Kudo-Saito, C., Tsukamoto, N., Ueda, R., Iwata-Kajihara, T., Nishio, H., Kawamura, N. & Kawakami, Y., 2011 Mar, In : International Journal of Hematology. 93, 3, p. 294-300 7 p.

Research output: Contribution to journalArticle

Immunosuppressive Agents
Neoplasms
Immunotherapy
Catenins
Epithelial-Mesenchymal Transition
2010
8 Citations (Scopus)

Partial regression of duodenal lesions of intestinal follicular lymphoma after antibiotic treatment

Yaguchi, T., Imaeda, H., Kizaki, M., Hosoe, N., Suzuki, H., Ogata, H., Iwao, Y., Kameyama, K., Ikeda, Y. & Hibi, T., 2010 Oct, In : Digestive Endoscopy. 22, 4, p. 316-318 3 p.

Research output: Contribution to journalArticle

Follicular Lymphoma
Anti-Bacterial Agents
Duodenum
Endoscopy
Lymphoma
2009
39 Citations (Scopus)

Emerging concepts in biomarker discovery; The US-Japan workshop on immunological molecular markers in oncology

Tahara, H., Sato, M., Thurin, M., Wang, E., Butterfield, L. H., Disis, M. L., Fox, B. A., Lee, P. P., Khleif, S. N., Wigginton, J. M., Ambs, S., Akutsu, Y., Chaussabel, D., Doki, Y., Eremin, O., Fridman, W. H., Hirohashi, Y., Imai, K., Jacobson, J., Jinushi, M. & 36 others, Kanamoto, A., Kashani-Sabet, M., Kato, K., Kawakami, Y., Kirkwood, J. M., Kleen, T. O., Lehmann, P. V., Liotta, L., Lotze, M. T., Maio, M., Malyguine, A., Masucci, G., Matsubara, H., Mayrand-Chung, S., Nakamura, K., Nishikawa, H., Karolina, A. K., Petricoin, E. F., Pos, Z., Ribas, A., Rivoltini, L., Sato, N., Shiku, H., Slingluff, C. L., Streicher, H., Stroncek, D. F., Takeuchi, H., Toyota, M., Wada, H., Wu, X., Wulfkuhle, J., Yaguchi, T., Zeskind, B., Zhao, Y., Zocca, M. B. & Marincola, F. M., 2009 Jun 17, In : Journal of Translational Medicine. 7, 45.

Research output: Contribution to journalArticle

Oncology
Biomarkers
Japan
Education
Biological Therapy
15 Citations (Scopus)

Involvement of hyaluronan and its receptor CD44 with choroidal neovascularization

Mochimaru, H., Takahashi, E., Tsukamoto, N., Miyazaki, J., Yaguchi, T., Koto, T., Kurihara, T., Noda, K., Ozawa, Y., Ishimoto, T., Kawakami, Y., Tanihara, H., Saya, H., Ishida, S. & Tsubota, K., 2009, In : Investigative Ophthalmology and Visual Science. 50, 9, p. 4410-4415 6 p.

Research output: Contribution to journalArticle

CD44 Antigens
Choroidal Neovascularization
Hyaluronic Acid
Light Coagulation
Lasers
28 Citations (Scopus)

Simultaneous suppression of MITF and BRAFV600E enhanced inhibition of melanoma cell proliferation

Kido, K., Sumimoto, H., Asada, S., Okada, S. M., Yaguchi, T., Kawamura, N., Miyagishi, M., Saida, T. & Kawakami, Y., 2009 Oct, In : Cancer Science. 100, 10, p. 1863-1869 7 p.

Research output: Contribution to journalArticle

Microphthalmia-Associated Transcription Factor
Melanoma
Cell Proliferation
Cell Line
2008
16 Citations (Scopus)

Dendritic cell based personalized immunotherapy based on cancer antigen research

Kawakami, Y., Fujita, T., Kudo, C., Sakurai, T., Udagawa, M., Yaguchi, T., Hasegawa, G., Hayashi, E., Ueda, Y., Iwata, T., Wang, Q., Okada, S., Tsukamoto, N., Matsuzaki, Y. & Sumimoto, H., 2008, In : Frontiers in Bioscience. 13, 5, p. 1952-1958 7 p.

Research output: Contribution to journalArticle

Immunotherapy
Dendritic Cells
Tumors
Antigens
Research
18 Citations (Scopus)

Suppression of alkali burn-induced corneal neovascularization by dendritic cell vaccination targeting VEGF receptor 2

Mochimaru, H., Usui, T., Yaguchi, T., Nagahama, Y., Hasegawa, G., Usui, Y., Shimmura, S., Tsubota, K., Amano, S., Kawakami, Y. & Ishida, S., 2008 Apr, In : Investigative Ophthalmology and Visual Science. 49, 5, p. 2172-2177 6 p.

Research output: Contribution to journalArticle

Corneal Neovascularization
Vascular Endothelial Growth Factor Receptor
Alkalies
Burns
Dendritic Cells
2007
11 Citations (Scopus)

Identification of a novel cancer-testis antigen CRT2 frequently expressed in various cancers using representational differential analysis

Hayashi, E., Matsuzaki, Y., Hasegawa, G., Yaguchi, T., Kurihara, S., Fujita, T., Kageshita, T., Sano, M. & Kawakami, Y., 2007 Nov 1, In : Clinical Cancer Research. 13, 21, p. 6267-6274 8 p.

Research output: Contribution to journalArticle

Testicular Neoplasms
Antigens
HLA-A24 Antigen
Neoplasms
Testis
10 Citations (Scopus)

Suppression of choroidal neovascularization by dendritic cell vaccination targeting VEGFR2

Mochimaru, H., Nagai, N., Hasegawa, G., Kudo-Saito, C., Yaguchi, T., Usui, Y., Kurihara, T., Koto, T., Satojuka, S., Shinoda, H., Ozawa, Y., Tsubota, K., Kawakami, Y. & Ishida, S., 2007 Oct, In : Investigative Ophthalmology and Visual Science. 48, 10, p. 4795-4801 7 p.

Research output: Contribution to journalArticle

Choroidal Neovascularization
Dendritic Cells
Vaccination
Peptides
Epitopes
2005
2 Citations (Scopus)

IgA nephropathy associated with polycythemia vera

Yaguchi, T., Takimoto, C., Uchimura, H., Konishi, K., Ichihara, A., Hayashi, K., Saruta, T. & Hashiguchi, A., 2005, In : Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine. 94, 8, p. 1612-1614 3 p.

Research output: Contribution to journalArticle

IGA Glomerulonephritis
Polycythemia Vera
Immunoglobulin A