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Fingerprint Dive into the research topics where Tomoyuki Ohe is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
Derivatives Chemical Compounds
Fullerenes Medicine & Life Sciences
Neuropeptide Y Receptors Medicine & Life Sciences
P-Glycoprotein Medicine & Life Sciences
Benzbromarone Medicine & Life Sciences
Cytochrome P-450 Enzyme System Medicine & Life Sciences
Structure-Activity Relationship Medicine & Life Sciences
Rats Chemical Compounds

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Research Output 1994 2019

  • 1092 Citations
  • 17 h-Index
  • 41 Article
  • 2 Review article

Synthesis and antitumor activity of novel pyridinium fullerene derivatives

Yasuno, T., Ohe, T., Ikeda, H., Takahashi, K., Nakamura, S. & Mashino, T., 2019 Jan 1, In : International journal of nanomedicine. 14, p. 6325-6337 13 p.

Research output: Contribution to journalArticle

Open Access
Fullerenes
Derivatives
Heterografts
Cell Line
Lead compounds

Hit-to-Lead in Academia: Discovery of a Protein-Protein Interaction Inhibitor of Keap1-Nrf2

Yasuda, D., Obata, R., Takahashi, K., Ohe, T. & Mashino, T., 2018 Jan 1, In : Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 138, 8, p. 1059-1065 7 p.

Research output: Contribution to journalReview article

Proteins
Drug Discovery
Kelch-Like ECH-Associated Protein 1
Lead
Protein Stability

Synthesis of novel benzbromarone derivatives designed to avoid metabolic activation

Ohe, T., Umezawa, R., Kitagawara, Y., Yasuda, D., Takahashi, K., Nakamura, S., Abe, A., Sekine, S., Ito, K., Okunushi, K., Morio, H., Furihata, T., Anzai, N. & Mashino, T., 2018 Jan 1, (Accepted/In press) In : Bioorganic and Medicinal Chemistry Letters.

Research output: Contribution to journalArticle

Benzbromarone
Uricosuric Agents
Chemical activation
Derivatives
Uric Acid
4 Citations (Scopus)

Alpha-tocopherol attenuates the anti-tumor activity of crizotinib against cells transformed by NPM-ALK

Uchihara, Y., Ueda, F., Tago, K., Nakazawa, Y., Ohe, T., Mashino, T., Yokota, S., Kasahara, T., Tamura, H. & Tago, M., 2017 Aug 1, In : PLoS One. 12, 8, e0183003.

Research output: Contribution to journalArticle

alpha-Tocopherol
lymphoma
alpha-tocopherol
Tumors
phosphotransferases (kinases)
7 Citations (Scopus)

Discovery of benzo[g]indoles as a novel class of non-covalent Keap1-Nrf2 protein-protein interaction inhibitor

Yasuda, D., Yuasa, A., Obata, R., Nakajima, M., Takahashi, K., Ohe, T., Ichimura, Y., Komatsu, M., Yamamoto, M., Imamura, R., Kojima, H., Okabe, T., Nagano, T. & Mashino, T., 2017 Nov 15, In : Bioorganic and Medicinal Chemistry Letters. 27, 22, p. 5006-5009 4 p.

Research output: Contribution to journalArticle

Indoles
Proteins
Hydroxamic Acids
Lead compounds
Derivatives