• 2713 Citations
  • 30 h-Index
19942019

Research output per year

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Research Output

  • 2713 Citations
  • 30 h-Index
  • 53 Article
  • 1 Short survey
  • 1 Review article
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Article
2019

Induction of human pluripotent stem cells into kidney tissues by synthetic mRNAs encoding transcription factors

Hiratsuka, K., Monkawa, T., Akiyama, T., Nakatake, Y., Oda, M., Goparaju, S. K., Kimura, H., Chikazawa-Nohtomi, N., Sato, S., Ishiguro, K., Yamaguchi, S., Suzuki, S., Morizane, R., Ko, S., Itoh, H. & Ko, M., 2019 Dec 1, In : Scientific Reports. 9, 1, 913.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2016

Generation of kidney tubular organoids from human pluripotent stem cells

Yamaguchi, S., Morizane, R., Honma, K., Monkawa, T., Suzuki, S., Fujii, S., Koda, M., Hiratsuka, K., Yamashita, M., Yoshida, T., Wakino, S., Hayashi, K., Sasaki, J., Hori, S. & Itoh, H., 2016 Dec 16, In : Scientific Reports. 6, 38353.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Immunoadsorption therapy for dilated cardiomyopathy using tryptophan column-A prospective, multicenter, randomized, within-patient and parallel-group comparative study to evaluate efficacy and safety

Yoshikawa, T., Baba, A., Akaishi, M., Wakabayashi, Y., Monkawa, T., Kitakaze, M., Izumi, T. & Tomoike, H., 2016, (Accepted/In press) In : Journal of Clinical Apheresis.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2015

A case of severe osteomalacia caused by Tubulointerstitial nephritis with Fanconi syndrome in asymptomotic primary biliary cirrhosis

Yamaguchi, S., Maruyama, T., Wakino, S., Tokuyama, H., Hashiguchi, A., Tada, S., Honma, K., Monkawa, T., Thomas, J. C., Miyashita, K., Kurihara, I., Yoshida, T., Konishi, K., Hayashi, K., Hayashi, M. & Itoh, H., 2015 Nov 11, (Accepted/In press) In : BMC Nephrology.

Research output: Contribution to journalArticle

6 Citations (Scopus)

miR-363 induces transdifferentiation of human kidney tubular cells to mesenchymal phenotype

Morizane, R., Fujii, S., Monkawa, T., Hiratsuka, K., Yamaguchi, S., Honma, K. & Itoh, H., 2015 Sep 15, (Accepted/In press) In : Clinical and Experimental Nephrology.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2014

MiR-34c attenuates epithelial-mesenchymal transition and kidney fibrosis with ureteral obstruction

Morizane, R., Fujii, S., Monkawa, T., Hiratsuka, K., Yamaguchi, S., Homma, K. & Itoh, H., 2014 Apr 3, In : Scientific reports. 4, 4578.

Research output: Contribution to journalArticle

41 Citations (Scopus)
2013

A curriculum for the board certified nephrologist (pediatric medicine)

Imai, H., Monkawa, T., Nakanishi, K., Kagami, S., Nagata, M., Hattori, M., Hataya, H., Kawasaki, Y., Kaku, Y., Kondo, S., Saito, H., Kamei, K., Tsuchida, S. & Goto, Y., 2013 Dec 1, In : Japanese Journal of Nephrology. 55, 8, p. 1348-1390 43 p.

Research output: Contribution to journalArticle

Kidney Specific Protein-Positive Cells Derived from Embryonic Stem Cells Reproduce Tubular Structures In Vitro and Differentiate into Renal Tubular Cells

Morizane, R., Monkawa, T., Fujii, S., Yamaguchi, S., Homma, K., Matsuzaki, Y., Okano, H. & Itoh, H., 2013 Jun 3, In : PloS one. 8, 6, e64843.

Research output: Contribution to journalArticle

31 Citations (Scopus)
2012

A novel compound heterozygous mutation of Gitelman's syndrome in Japan, as diagnosed by an extraordinary response of the fractional excretion rate of chloride in the trichlormethiazide loading test

Ueda, K., Makita, N., Kawarazaki, H., Fujiwara, T., Unuma, S., Monkawa, T., Hayashi, M. & Fujita, T., 2012 Jul 3, In : Internal Medicine. 51, 12, p. 1549-1553 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Selective depletion of mouse kidney proximal straight tubule cells causes acute kidney injury

Sekine, M., Monkawa, T., Morizane, R., Matsuoka, K., Taya, C., Akita, Y., Joh, K., Itoh, H., Hayashi, M., Kikkawa, Y., Kohno, K., Suzuki, A. & Yonekawa, H., 2012 Feb 1, In : Transgenic research. 21, 1, p. 51-62 12 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
2011

[Curriculum for the board certified nephrologist (internal medicine)].

Imai, H., Monkawa, T., Wada, T., Fujigaki, Y., Ito, T., Kanno, Y., Kiyomoto, H., Matsumura, M., Ohara, M., Saito, C., Uchida, K., Yasuda, T. & Yoshida, A., 2011 Dec 1, In : Nihon Jinzo Gakkai shi. 53, 8, p. 1074-1138 65 p.

Research output: Contribution to journalArticle

Renal amyloidosis caused by apolipoprotein A-II without a genetic mutation in the coding sequence

Morizane, R., Monkawa, T., Konishi, K., Hashiguchi, A., Ueda, M., Ando, Y., Tokuyama, H., Hayashi, K., Hayashi, M. & Itoh, H., 2011 Oct 1, In : Clinical and experimental nephrology. 15, 5, p. 774-779 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Specific immunoadsorption therapy using a tryptophan column in patients with refractory heart failure due to dilated cardiomyopathy

Nagatomo, Y., Baba, A., Ito, H., Naito, K., Yoshizawa, A., Kurita, Y., Nakamura, I., Monkawa, T., Matsubara, T., Wakabayashi, Y., Ogawa, S., Akaishi, M. & Yoshikawa, T., 2011 Feb 23, In : Journal of Clinical Apheresis. 26, 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

The role of microRNA-145 in human embryonic stem cell differentiation into vascular cells

Yamaguchi, S., Yamahara, K., Homma, K., Suzuki, S., Fujii, S., Morizane, R., Monkawa, T., Matsuzaki, Y., Kangawa, K. & Itoh, H., 2011 Dec 1, In : Atherosclerosis. 219, 2, p. 468-474 7 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)
2010

Complete elimination of cardiodepressant IgG3 autoantibodies by immunoadsorption in patients with severe heart failure

Baba, A., Akaishi, M., Shimada, M., Monkawa, T., Wakabayashi, Y., Takahashi, M., Nagatomo, Y. & Yoshikawa, T., 2010 Jan 1, In : Circulation Journal. 74, 7, p. 1372-1378 7 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Fibroblast expression of an IκB dominant-negative transgene attenuates renal fibrosis

Inoue, T., Takenaka, T., Hayashi, M., Monkawa, T., Yoshino, J., Shimoda, K., Neilson, E. G., Suzuki, H. & Okada, H., 2010 Dec 1, In : Journal of the American Society of Nephrology. 21, 12, p. 2047-2052 6 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Heart failure causes cholinergic transdifferentiation of cardiac sympathetic nerves via gp130-signaling cytokines in rodents

Kanazawa, H., Ieda, M., Kimura, K., Arai, T., Kawaguchi-Manabe, H., Matsuhashi, T., Endo, J., Sano, M., Kawakami, T., Kimura, T., Monkawa, T., Hayashi, M., Iwanami, A., Okano, H., Okada, Y., Ishibashi-Ueda, H., Ogawa, S. & Fukuda, K., 2010 Feb 1, In : Journal of Clinical Investigation. 120, 2, p. 408-421 14 p.

Research output: Contribution to journalArticle

79 Citations (Scopus)
2009

Differentiation of murine embryonic stem and induced pluripotent stem cells to renal lineage in vitro

Morizane, R., Monkawa, T. & Itoh, H., 2009 Dec 25, In : Biochemical and Biophysical Research Communications. 390, 4, p. 1334-1339 6 p.

Research output: Contribution to journalArticle

83 Citations (Scopus)
2007

A case of Henoch-Schönlein purpura in a patient on hemodialysis

Yoshino, J., Sasamura, H., Konishi, K., Tsuji, M., Suda, N., Yoshida, T., Monkawa, T., Hayashi, M. & Itoh, H., 2007 Feb 27, In : Japanese Journal of Nephrology. 49, 1, p. 49-53 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Snail1 is involved in the renal epithelial-mesenchymal transition

Yoshino, J., Monkawa, T., Tsuji, M., Inukai, M., Itoh, H. & Hayashi, M., 2007 Oct 12, In : Biochemical and Biophysical Research Communications. 362, 1, p. 63-68 6 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)
2006

Microarray analysis of a reversible model and an irreversible model of anti-Thy-1 nephritis

Tsuji, M., Monkawa, T., Yoshino, J., Asai, M., Fukuda, S., Kawachi, H., Shimizu, F., Hayashi, M. & Saruta, T., 2006 Mar 1, In : Kidney international. 69, 6, p. 996-1004 9 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

The cyclin-dependent kinase inhibitor p21 limits murine mesangial proliferative glomerulonephritis

Monkawa, T., Pippin, J., Yo, Y., Kopp, J. B., Alpers, C. E. & Shankland, S. J., 2006 Jan 1, In : Nephron - Experimental Nephrology. 102, 1, p. e8-e18

Research output: Contribution to journalArticle

10 Citations (Scopus)
2005

Mechanical stretch induces podocyte hypertrophy in vitro

Petermann, A. T., Pippin, J., Durvasula, R., Pichler, R., Hiromura, E., Monkawa, T., Couser, W. G. & Shankland, S. J., 2005 Jan, In : Kidney international. 67, 1, p. 157-166 10 p.

Research output: Contribution to journalArticle

75 Citations (Scopus)
2004

Comparison of the effects calcitriol and maxacalcitol on secondary hyperparathyroidism in patients on chronic haemodialysis: A randomized propective multicenter trial

Hayashi, M., Tsuchiya, Y., Itaya, Y., Takenaka, T., Kobayashi, K., Yoshizawa, M., Nakamura, R., Monkawa, T. & Ichihara, A., 2004 Aug 1, In : Nephrology Dialysis Transplantation. 19, 8, p. 2067-2073 7 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Expression of the Na+/H+ exchanger regulatory protein family in genetically hypertensive rats

Kobayashi, K., Monkawa, T., Hayashi, M. & Saruta, T., 2004 Sep 1, In : Journal of hypertension. 22, 9, p. 1723-1730 8 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Spironolactone in combination with cilazapril ameliorates proteinuria and renal interstitial fibrosis in rats with anti-Thy-1 irreversible nephritis

Asai, M., Monkawa, T., Marumo, T., Fukuda, S., Tsuji, M., Yoshino, J., Kawachi, H., Shimizu, F., Hayashi, M. & Saruta, T., 2004 Dec 1, In : Hypertension Research. 27, 12, p. 971-978 8 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
2003

Leukemia Inhibitory Factor Is Involved in Tubular Regeneration after Experimental Acute Renal Failure

Yoshino, J., Monkawa, T., Tsuji, M., Hayashi, M. & Saruta, T., 2003 Dec 1, In : Journal of the American Society of Nephrology. 14, 12, p. 3090-3101 12 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Mitotic cell cycle proteins increase in podocytes despite lack of proliferation

Petermann, A. T., Pippin, J., Hiromura, K., Monkawa, T., Durvasula, R., Couser, W. G., Kopp, J. & Shankland, S. J., 2003 Jan 1, In : Kidney international. 63, 1, p. 113-122 10 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)
2002

Insulin is a potent survival factor in mesangial cells: Role of the PI3-kinase/Akt pathway

Hiromura, K., Monkawa, T., Petermann, A. T., Durvasula, R. V. & Shankland, S. J., 2002 Jan 1, In : Kidney international. 61, 4, p. 1312-1321 10 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Mechanical stress reduces podocyte proliferation in vitro

Petermann, A. T., Hiromura, K., Blonski, M., Pippin, J., Monkawa, T., Durvasula, R., Couser, W. G. & Shankland, S. J., 2002 Jan 1, In : Kidney international. 61, 1, p. 40-50 11 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)

The hypertrophic effect of transforming growth factor-β is reduced in the absence of cyclin-dependent kinase-inhibitors p21 and p27

Monkawa, T., Hiromura, K., Wolf, G. & Shankland, S. J., 2002 May 7, In : Journal of the American Society of Nephrology. 13, 5, p. 1172-1178 7 p.

Research output: Contribution to journalArticle

67 Citations (Scopus)
2001

A New Member of the HCO3- Transporter Superfamily Is an Apical Anion Exchanger of β-Intercalated Cells in the Kidney

Tsuganezawa, H., Kobayashi, K., Iyori, M., Araki, T., Koizumi, A., Watanabe, S. I., Kaneko, A., Fukao, T., Monkawa, T., Yoshida, T., Kim, D. K., Kanai, Y., Endou, H., Hayashi, M. & Saruta, T., 2001 Mar 16, In : Journal of Biological Chemistry. 276, 11, p. 8180-8189 10 p.

Research output: Contribution to journalArticle

116 Citations (Scopus)

Dietary phosphorus deprivation induces 25-hydroxyvitamin D3 1α-hydroxylase gene expression

Yoshida, T., Yoshida, N., Monkawa, T., Hayashi, M. & Saruta, T., 2001 Jan 1, In : Endocrinology. 142, 5, p. 1720-1726 7 p.

Research output: Contribution to journalArticle

Open Access
52 Citations (Scopus)

Podocyte expression of the CDK-inhibitor p57 during development and disease

Hiromura, K., Haseley, L. A., Zhang, P., Monkawa, T., Durvasula, R., Petermann, A. T., Alpers, C. E., Mundel, P. & Shankland, S. J., 2001 Jan 1, In : Kidney international. 60, 6, p. 2235-2246 12 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)
2000

Identification of 25-hydroxyvitamin D3 1α-hydroxylase gene expression in macrophages

Monkawa, T., Yoshida, T., Hayashi, M. & Saruta, T., 2000 Jan 1, In : Kidney international. 58, 2, p. 559-568 10 p.

Research output: Contribution to journalArticle

92 Citations (Scopus)

Novel mutations in thiazide-sensitive Na-Cl cotransporter gene of patients with Gitelman's syndrome

Monkawa, T., Kurihara, I., Kobayashi, K., Hayashi, M. & Saruta, T., 2000 Jan 1, In : Journal of the American Society of Nephrology. 11, 1, p. 65-70 6 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)
1999

Calcitonin induces 25-hydroxyvitamin D3 1α-hydroxylase mRNA expression via protein kinase C pathway in LLC-PK1 cells

Yoshida, N., Yoshida, T., Nakamura, A., Monkawa, T., Hayashi, M. & Saruta, T., 1999 Dec 1, In : Journal of the American Society of Nephrology. 10, 12, p. 2474-2479 6 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Cloning of porcine 25-hydroxyvitamin D3 1α-hydroxylase and its regulation by cAMP in LLC-PK1 cells

Yoshida, T., Yoshida, N., Nakamura, A., Monkawa, T., Hayashi, M. & Saruta, T., 1999 May 1, In : Journal of the American Society of Nephrology. 10, 5, p. 963-970 8 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Intracellular calcium concentration in the inositol trisphosphate receptor type 1 knockout mouse

Hayashi, M., Monkawa, T., Yoshida, T., Sasamura, H., Matsumoto, M., Inoue, T., Mikoshiba, K. & Saruta, T., 1999 Oct 1, In : Journal of the American Society of Nephrology. 10, 10, p. 2094-2101 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
1998

Localization of inositol 1,4,5-trisphosphate receptors in the rat kidney

Monkawa, T., Hayashi, M., Miyawaki, A., Sugiyama, T., Yamamoto-Hino, M., Hasegawa, M., Furuichi, T., Mikoshiba, K. & Saruta, T., 1998 Jan 1, In : Kidney international. 53, 2, p. 296-301 6 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Serum leptin concentrations in patients with thyroid disorders

Yoshida, T., Momotani, N., Hayashi, M., Monkawa, T., Ito, K. & Saruta, T., 1998 Apr 7, In : Clinical Endocrinology. 48, 3, p. 299-302 4 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)

Two novel 1α-hydroxylase mutations in French-Canadians with vitamin D dependency rickets type I

Yoshida, T., Monkawa, T., Tenenhouse, H. S., Goodyer, P., Shinki, T., Suda, T., Wakino, S., Hayashi, M. & Saruta, T., 1998 Jan 1, In : Kidney international. 54, 5, p. 1437-1443 7 p.

Research output: Contribution to journalArticle

69 Citations (Scopus)
1997

Expression and localization of the water channels in human autosomal dominant polycystic kidney disease

Hayashi, M., Yamaji, Y., Monkawa, T., Yoshida, T., Tsuganezawa, H., Sasamura, H., Kitajima, W., Sasaki, S., Ishibashi, K., Maurmo, F. & Saruta, T., 1997 Jan 1, In : Nephron. 75, 3, p. 321-326 6 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Molecular cloning of cDNA and genomic DNA for human 25-hydroxyvitamin D3 1α-hydroxylase

Monkawa, T., Yoshida, T., Wakino, S., Shinki, T., Anazawa, H., DeLuca, H. F., Suda, T., Hayashi, M. & Saruta, T., 1997 Oct 20, In : Biochemical and Biophysical Research Communications. 239, 2, p. 527-533 7 p.

Research output: Contribution to journalArticle

137 Citations (Scopus)

Na+/H+-exchanger 3 activity and its gene in the spontaneously hypertensive rat kidney

Hayashi, M., Yoshida, T., Monkawa, T., Yamaji, Y., Sato, S. & Saruta, T., 1997 Feb 24, In : Journal of hypertension. 15, 1, p. 43-48 6 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)

Regulation of expression of leptin mRNA and secretion of leptin by thyroid hormone in 3T3-L1 adipocytes

Yoshida, T., Monkawa, T., Hayashi, M. & Saruta, T., 1997 Mar 27, In : Biochemical and Biophysical Research Communications. 232, 3, p. 822-826 5 p.

Research output: Contribution to journalArticle

86 Citations (Scopus)
1996

Mutational analysis of the ligand binding site of the inositol 1,4,5- trisphosphate receptor

Yoshikawa, F., Morita, M., Monkawa, T., Michikawa, T., Furuichi, T. & Mikoshiba, K., 1996 Aug 10, In : Journal of Biological Chemistry. 271, 30, p. 18277-18284 8 p.

Research output: Contribution to journalArticle

182 Citations (Scopus)

Regulation of obese mRNA expression by hormonal factors in primary cultures of rat adipocytes

Yoshida, T., Hayashi, M., Monkawa, T. & Saruta, T., 1996 Nov, In : European journal of endocrinology. 135, 5, p. 619-625 7 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Role of vasopressin V2 receptor in acute regulation of aquaporin-2

Hayashi, M., Sasaki, S., Tsuganezawa, H., Monkawa, T., Kitajima, W., Fushimi, K., Marumo, F. & Saruta, T., 1996 Jan 1, In : Kidney and Blood Pressure Research. 19, 1, p. 32-37 6 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)
1995

Heterotetrameric complex formation of inositol 1,4,5-trisphosphate receptor subunits

Monkawa, T., Miyawaki, A., Sugiyama, T., Yoneshima, H., Yamamoto-Hino, M., Furuichi, T., Saruta, T., Hasegawa, M. & Mikoshiba, K., 1995 Jun 16, In : Journal of Biological Chemistry. 270, 24, p. 14700-14704 5 p.

Research output: Contribution to journalArticle

185 Citations (Scopus)