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Research Output 1998 2019

  • 1596 Citations
  • 20 h-Index
  • 50 Article
  • 5 Chapter
  • 5 Review article
  • 1 Conference contribution
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Article
2019
3 Citations (Scopus)

Application of high-performance magnetic nanobeads to biological sensing devices

Kabe, Y., Sakamoto, S., Hatakeyama, M., Yamaguchi, Y., Suematsu, M., Itonaga, M. & Handa, H., 2019 Jan 1, (Accepted/In press) In : Analytical and Bioanalytical Chemistry.

Research output: Contribution to journalArticle

Exosomes
Equipment and Supplies
Technology
Immunoassay
Drug Receptors

Environmental Optimization Enables Maintenance of Quiescent Hematopoietic Stem Cells Ex Vivo

Kobayashi, H., Morikawa, T., Okinaga, A., Hamano, F., Hashidate-Yoshida, T., Watanuki, S., Hishikawa, D., Shindou, H., Arai, F., Kabe, Y., Suematsu, M., Shimizu, T. & Takubo, K., 2019 Jul 2, In : Cell Reports. 28, 1, p. 145-158.e9

Research output: Contribution to journalArticle

Open Access
Hematopoietic Stem Cells
Stem cells
Maintenance
Fatty Acids
Cell culture

Identification of a binding protein for sesamin and characterization of its roles in plant growth

Tera, M., Koyama, T., Murata, J., Furukawa, A., Mori, S., Azuma, T., Watanabe, T., Hori, K., Okazawa, A., Kabe, Y., Suematsu, M., Satake, H., Ono, E. & Horikawa, M., 2019 Dec 1, In : Scientific reports. 9, 1, 8631.

Research output: Contribution to journalArticle

Open Access
Carrier Proteins
Growth
Sesamum
sesamin
Lignans
2018
9 Citations (Scopus)

Baicalein Targets GTPase-Mediated Autophagy to Eliminate Liver Tumor–Initiating Stem Cell–Like Cells Resistant to mTORC1 Inhibition

Wu, R., Murali, R., Kabe, Y., French, S. W., Chiang, Y. M., Liu, S., Sher, L., Wang, C. C., Louie, S. & Tsukamoto, H., 2018 Nov 1, In : Hepatology. 68, 5, p. 1726-1740 15 p.

Research output: Contribution to journalArticle

GTP Phosphohydrolases
Autophagy
Sirolimus
Stem Cells
Liver
7 Citations (Scopus)

Development of a highly sensitive device for counting the number of disease-specific exosomes in human sera

Kabe, Y., Suematsu, M., Sakamoto, S., Hirai, M., Koike, I., Hishiki, T., Matsuda, A., Hasegawa, Y., Tsujita, K., Ono, M., Minegishi, N., Hozawa, A., Murakami, Y., Kubo, M., Itonaga, M. & Handa, H., 2018 Oct 1, In : Clinical Chemistry. 64, 10, p. 1463-1473 11 p.

Research output: Contribution to journalArticle

Exosomes
Equipment and Supplies
CD147 Antigens
Serum
Flow cytometry
17 Citations (Scopus)

Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival

Shiota, M., Naya, M., Yamamoto, T., Hishiki, T., Tani, T., Takahashi, H., Kubo, A., Koike, D., Itoh, M., Ohmura, M., Kabe, Y., Sugiura, Y., Hiraoka, N., Morikawa, T., Takubo, K., Suina, K., Nagashima, H., Sampetrean, O., Nagano, O., Saya, H. & 3 others, Yamazoe, S., Watanabe, H. & Suematsu, M., 2018 Dec 1, In : Nature Communications. 9, 1, 1561.

Research output: Contribution to journalArticle

Raman Spectrum Analysis
Oxidants
Gold
Raman spectroscopy
tumors
2017
1 Citation (Scopus)
Oligodendroglia
Thyroid Hormones
Adult Stem Cells
Core Binding Factor Alpha 2 Subunit
Cyclin-Dependent Kinase Inhibitor p15
20 Citations (Scopus)

Sigma-2 receptor and progesterone receptor membrane component 1 (PGRMC1) are two different proteins: Proofs by fluorescent labeling and binding of sigma-2 receptor ligands to PGRMC1

Pati, M. L., Groza, D., Riganti, C., Kopecka, J., Niso, M., Berardi, F., Hager, S., Heffeter, P., Hirai, M., Tsugawa, H., Kabe, Y., Suematsu, M. & Abate, C., 2017 Mar 1, In : Pharmacological Research. 117, p. 67-74 8 p.

Research output: Contribution to journalArticle

Progesterone Receptors
Ligands
Membranes
Proteins
Heme
9 Citations (Scopus)

Somatic KCNJ5 mutation occurring early in adrenal development may cause a novel form of juvenile primary aldosteronism

Tamura, A., Nishimoto, K., Seki, T., Matsuzawa, Y., Saito, J., Omura, M., Gomez-Sanchez, C. E., Makita, K., Matsui, S., Moriya, N., Inoue, A., Nagata, M., Sasano, H., Nakamura, Y., Yamazaki, Y., Kabe, Y., Mukai, K., Kosaka, T., Oya, M., Suematsu, S. & 1 others, Nishikawa, T., 2017 Feb 5, In : Molecular and Cellular Endocrinology. 441, p. 134-139 6 p.

Research output: Contribution to journalArticle

Hyperaldosteronism
Aldosterone
Cytochrome P-450 CYP11B2
Adrenal Glands
Mutation
26 Citations (Scopus)

Stearoyl-CoA Desaturase Promotes Liver Fibrosis and Tumor Development in Mice via a Wnt Positive-Signaling Loop by Stabilization of Low-Density Lipoprotein-Receptor-Related Proteins 5 and 6

Lai, K. K. Y., Kweon, S. M., Chi, F., Hwang, E., Kabe, Y., Higashiyama, R., Qin, L., Yan, R., Wu, R. P., Lai, K., Fujii, N., French, S., Xu, J., Wang, J. Y., Murali, R., Mishra, L., Lee, J. S., Ntambi, J. M. & Tsukamoto, H., 2017 May 1, In : Gastroenterology. 152, 6, p. 1477-1491 15 p.

Research output: Contribution to journalArticle

Low Density Lipoprotein Receptor-Related Protein-6
Low Density Lipoprotein Receptor-Related Protein-5
Stearoyl-CoA Desaturase
Liver Cirrhosis
Hepatic Stellate Cells
2016
4 Citations (Scopus)

Alteration of matrix metalloproteinase-3 O-glycan structure as a biomarker for disease activity of rheumatoid arthritis

Takeshita, M., Kuno, A., Suzuki, K., Matsuda, A., Shimazaki, H., Nakagawa, T., Otomo, Y., Kabe, Y., Suematsu, M., Narimatsu, H. & Takeuchi, T., 2016 May 21, In : Arthritis Research and Therapy. 18, 1, 112.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 3
Polysaccharides
Rheumatoid Arthritis
Biomarkers
Agrocybe
2 Citations (Scopus)

Disorganized Steroidogenesis in Adrenocortical Carcinoma, a Case Study

Uchida, T., Nishimoto, K., Fukumura, Y., Asahina, M., Goto, H., Kawano, Y., Shimizu, F., Tsujimura, A., Seki, T., Mukai, K., Kabe, Y., Suematsu, M., Gomez-Sanchez, C. E., Yao, T., Horie, S. & Watada, H., 2016 Jul 18, (Accepted/In press) In : Endocrine Pathology. p. 1-9 9 p.

Research output: Contribution to journalArticle

Adrenocortical Carcinoma
Steroid 11-beta-Hydroxylase
Cytochrome P-450 CYP11B2
Hydrocortisone
Aldosterone
55 Citations (Scopus)

Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance

Kabe, Y., Nakane, T., Koike, I., Yamamoto, T., Sugiura, Y., Harada, E., Sugase, K., Shimamura, T., Ohmura, M., Muraoka, K., Yamamoto, A., Uchida, T., Iwata, S., Yamaguchi, Y., Krayukhina, E., Noda, M., Handa, H., Ishimori, K., Uchiyama, S., Kobayashi, T. & 1 others, Suematsu, M., 2016 Mar 18, In : Nature Communications. 7, 11030.

Research output: Contribution to journalArticle

Dimerization
dimerization
Heme
cancer
cytochromes
20 Citations (Scopus)

Human Adrenocortical Remodeling Leading to Aldosterone-Producing Cell Cluster Generation

Nishimoto, K., Seki, T., Hayashi, Y., Mikami, S., Al-Eyd, G., Nakagawa, K., Morita, S., Kosaka, T., Oya, M., Mitani, F., Suematsu, M., Kabe, Y. & Mukai, K., 2016, In : International Journal of Endocrinology. 2016, 7834356.

Research output: Contribution to journalArticle

Aldosterone
Cytochrome P-450 CYP11B2
Steroid 11-beta-Hydroxylase
Zona Fasciculata
Zona Glomerulosa
2015

Correction: LATS1 and LATS2 phosphorylate CDC26 to modulate assembly of the tetratricopeptide repeat subcomplex of APC/C

Masuda, K., Chiyoda, T., Sugiyama, N., Segura-Cabrera, A., Kabe, Y., Ueki, A., Banno, K., Suematsu, M., Aoki, D., Ishihama, Y., Saya, H. & Kuninaka, S., 2015 Apr 10, In : PLoS One. 10, 4, e0125308.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Impacts of CD44 knockdown in cancer cells on tumor and host metabolic systems revealed by quantitative imaging mass spectrometry

Ohmura, M., Hishiki, T., Yamamoto, T., Nakanishi, T., Kubo, A., Tsuchihashi, K., Tamada, M., Toue, S., Kabe, Y., Saya, H. & Suematsu, M., 2015 Apr 30, In : Nitric Oxide - Biology and Chemistry. 46, p. 102-113 12 p.

Research output: Contribution to journalArticle

Mass spectrometry
Tumors
Mass Spectrometry
Cells
Imaging techniques
8 Citations (Scopus)

LATS1 and LATS2 phosphorylate CDC26 to modulate assembly of the tetratricopeptide repeat subcomplex of APC/C

Masuda, K., Chiyoda, T., Sugiyama, N., Segura-Cabrera, A., Kabe, Y., Ueki, A., Banno, K., Suematsu, M., Aoki, D., Ishihama, Y., Saya, H. & Kuninaka, S., 2015 Feb 27, In : PLoS One. 10, 2, e0118662.

Research output: Contribution to journalArticle

Anaphase-Promoting Complex-Cyclosome
Tumors
phosphotransferases (kinases)
Phosphorylation
Phosphotransferases
2014
28 Citations (Scopus)

Microscopic imaging mass spectrometry assisted by on-tissue chemical derivatization for visualizing multiple amino acids in human colon cancer xenografts

Toue, S., Sugiura, Y., Kubo, A., Ohmura, M., Karakawa, S., Mizukoshi, T., Yoneda, J., Miyano, H., Noguchi, Y., Kobayashi, T., Kabe, Y. & Suematsu, M., 2014, In : Proteomics. 14, 7-8, p. 810-819 10 p.

Research output: Contribution to journalArticle

Heterografts
Colonic Neoplasms
Mass spectrometry
Mass Spectrometry
Tissue
2013
6 Citations (Scopus)

Vesnarinone suppresses TNFa mRNA expression by inhibiting valosin-containing protein

Hotta, K., Nashimoto, A., Yasumura, E., Suzuki, M., Azuma, M., Iizumi, Y., Shima, D., Nabeshima, R., Hiramoto, M., Okada, A., Sakata-Sogawa, K., Tokunaga, M., Ito, T., Ando, H., Sakamoto, S., Kabe, Y., Aizawa, S., Imai, T., Yamaguchi, Y., Watanabe, H. & 1 others, Handa, H., 2013 May, In : Molecular Pharmacology. 83, 5, p. 930-938 9 p.

Research output: Contribution to journalArticle

Messenger RNA
Agranulocytosis
Heart Neoplasms
Quinolones
Treatment Failure
20 Citations (Scopus)

Vitamin K2 covalently binds to bak and induces bak-mediated apoptosiss

Karasawa, S., Azuma, M., Kasama, T., Sakamoto, S., Kabe, Y., Imai, T., Yamaguchi, Y., Miyazawa, K. & Handa, H., 2013 Mar, In : Molecular Pharmacology. 83, 3, p. 613-620 8 p.

Research output: Contribution to journalArticle

Vitamin K 2
Apoptosis
bcl-2-Associated X Protein
Epoxy Compounds
Cytochromes c
2012
51 Citations (Scopus)

HIF-1α induction suppresses excessive lipid accumulation in alcoholic fatty liver in mice

Nishiyama, Y., Goda, N., Kanai, M., Niwa, D., Osanai, K., Yamamoto, Y., Senoo-Matsuda, N., Johnson, R. S., Miura, S., Kabe, Y. & Suematsu, M., 2012 Feb, In : Journal of Hepatology. 56, 2, p. 441-447 7 p.

Research output: Contribution to journalArticle

Alcoholic Fatty Liver
Hypoxia-Inducible Factor 1
Lipids
Ethanol
Liver
142 Citations (Scopus)

Hypoxic regulation of the cerebral microcirculation is mediated by a carbon monoxide-sensitive hydrogen sulfide pathway

Morikawa, T., Kajimura, M., Nakamura, T., Hishiki, T., Nakanishi, T., Yukutake, Y., Nagahata, Y., Ishikawa, M., Hattori, K., Takenouchi, T., Takahashi, T., Ishii, I., Matsubara, K., Kabe, Y., Uchiyama, S., Nagata, E., Gadalla, M. M., Snyder, S. H. & Suematsu, M., 2012 Jan 24, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 4, p. 1293-1298 6 p.

Research output: Contribution to journalArticle

Hydrogen Sulfide
Carbon Monoxide
Microcirculation
Vasodilation
Brain Hypoxia
13 Citations (Scopus)

Involvement of NF-κB-mediated expression of galectin-3- binding protein in TNF-α-induced breast cancer cell adhesion

Noma, N., Simizu, S., Kambayashi, Y., Kabe, Y., Suematsu, M. & Umezawa, K., 2012 Jun, In : Oncology Reports. 27, 6, p. 2080-2084 5 p.

Research output: Contribution to journalArticle

Galectin 3
Cell Adhesion
Carrier Proteins
Breast Neoplasms
Neoplasms
2010
15 Citations (Scopus)

Identification of dynamin-2-mediated endocytosis as a new target of osteoporosis drugs, bisphosphonates

Masaike, Y., Takagi, T., Hirota, M., Yamada, J., Ishihara, S., Yung, T. M. C., Inoue, T., Sawa, C., Sagara, H., Sakamoto, S., Kabe, Y., Takahashi, Y., Yamaguchi, Y. & Handa, H., 2010 Feb, In : Molecular Pharmacology. 77, 2, p. 262-269 8 p.

Research output: Contribution to journalArticle

Dynamin II
Diphosphonates
Endocytosis
Osteoporosis
Prenylation
2009
32 Citations (Scopus)

Capsaicin binds to prohibitin 2 and displaces it from the mitochondria to the nucleus

Kuramori, C., Azuma, M., Kume, K., Kaneko, Y., Inoue, A., Yamaguchi, Y., Kabe, Y., Hosoya, T., Kizaki, M., Suematsu, M. & Handa, H., 2009 Feb 6, In : Biochemical and Biophysical Research Communications. 379, 2, p. 519-525 7 p.

Research output: Contribution to journalArticle

Mitochondria
Capsaicin
Apoptosis
Food additives
Food Additives
47 Citations (Scopus)

Development and application of high-performance affinity beads: Toward chemical biology and drug discovery

Sakamoto, S., Kabe, Y., Hatakeyama, M., Yamaguchi, Y. & Handa, H., 2009, In : Chemical Record. 9, 1, p. 66-85 20 p.

Research output: Contribution to journalArticle

Drug Discovery
Purification
Pharmaceutical Preparations
Affinity chromatography
Research
13 Citations (Scopus)

Inhibitory effect of N,N-didesmethylgrossularine-1 on inflammatory cytokine production in lipopolysaccharide-stimulated RAW 264.7 cells

Oda, T., Lee, J. S., Sato, Y., Kabe, Y., Sakamoto, S., Handa, H., Mangindaan, R. E. P. & Namikoshi, M., 2009 Dec, In : Marine Drugs. 7, 4, p. 589-599 11 p.

Research output: Contribution to journalArticle

Lipopolysaccharides
Cytokines
Carbolines
Urochordata
Interleukin-8
10 Citations (Scopus)

Mono-(2-ethylhexyl) phthalate targets glycogen debranching enzyme and affects glycogen metabolism in rat testis

Kuramori, C., Hase, Y., Hoshikawa, K., Watanabe, K., Nishi, T., Hishiki, T., Soga, T., Nashimoto, A., Kabe, Y., Yamaguchi, Y., Watanabe, H., Kataoka, K., Suematsu, M. & Handa, H., 2009, In : Toxicological Sciences. 109, 1, p. 143-151 9 p.

Research output: Contribution to journalArticle

Glycogen Debranching Enzyme System
Glycogen
Metabolism
Testis
Rats
8 Citations (Scopus)

Preparation of conophylline affinity nano-beads and identification of a target protein

Suzuki, E., Ogura, H., Kato, K., Takei, I., Kabe, Y., Handa, H. & Umezawa, K., 2009 Sep 1, In : Bioorganic and Medicinal Chemistry. 17, 17, p. 6188-6195 8 p.

Research output: Contribution to journalArticle

Proteins
Vinca Alkaloids
Latex
Microspheres
Purification
53 Citations (Scopus)

The Ape-1/Ref-1 redox antagonist E3330 inhibits the growth of tumor endothelium and endothelial progenitor cells: therapeutic implications in tumor angiogenesis

Zou, G. M., Karikari, C., Kabe, Y., Handa, H., Anders, R. A. & Maitraz, A., 2009 Apr, In : Journal of Cellular Physiology. 219, 1, p. 209-218 10 p.

Research output: Contribution to journalArticle

Endothelial cells
Hominidae
Oxidation-Reduction
Endothelium
Tumors
2008
36 Citations (Scopus)

Adenine nucleotide translocator transports haem precursors into mitochondria

Azuma, M., Kabe, Y., Kuramori, C., Kondo, M., Yamaguchi, Y. & Handa, H., 2008 Aug 27, In : PLoS One. 3, 8, e3070.

Research output: Contribution to journalArticle

Mitochondria
Adenine Nucleotides
Heme
mitochondria
protoporphyrin
88 Citations (Scopus)

A new APE1/Ref-1-dependent pathway leading to reduction of NF-κB and AP-1, and activation of their DNA-binding activity

Ando, K., Hirao, S., Kabe, Y., Ogura, Y., Sato, I., Yamaguchi, Y., Wada, T. & Handa, H., 2008 Aug, In : Nucleic Acids Research. 36, 13, p. 4327-4336 10 p.

Research output: Contribution to journalArticle

Transcription Factor AP-1
DNA-(Apurinic or Apyrimidinic Site) Lyase
Transcription Factors
DNA Repair
DNA
13 Citations (Scopus)
Preclinical Drug Evaluations
Signal Recognition Particle
Type II DNA Topoisomerase
HEK293 Cells
Microspheres
38 Citations (Scopus)

Atrazine binds to F1F0-ATP synthase and inhibits mitochondrial function in sperm

Hase, Y., Tatsuno, M., Nishi, T., Kataoka, K., Kabe, Y., Yamaguchi, Y., Ozawa, N., Natori, M., Handa, H. & Watanabe, H., 2008 Feb 1, In : Biochemical and Biophysical Research Communications. 366, 1, p. 66-72 7 p.

Research output: Contribution to journalArticle

Atrazine
Spermatozoa
Triazines
Mitochondria
Mitochondrial Proton-Translocating ATPases
2 Citations (Scopus)

Development of a chemical screening system using aqueorin-fused protein

Suzuki, M., Furukawa, S., Kuramori, C., Sawa, C., Kabe, Y., Nakamura, M., Sawada, J. I., Yamaguchi, Y., Sakamoto, S., Inouye, S. & Handa, H., 2008 Apr 11, In : Biochemical and Biophysical Research Communications. 368, 3, p. 600-605 6 p.

Research output: Contribution to journalArticle

Aequorin
Tetrahydrofolate Dehydrogenase
Screening
Methotrexate
Proteins
2007
32 Citations (Scopus)

hnRNP-U enhances the expression of specific genes by stabilizing mRNA

Yugami, M., Kabe, Y., Yamaguchi, Y., Wada, T. & Handa, H., 2007 Jan 9, In : FEBS Letters. 581, 1, p. 1-7 7 p.

Research output: Contribution to journalArticle

Heterogeneous-Nuclear Ribonucleoprotein U
Genes
Gene Expression
Messenger RNA
Matrix Attachment Regions
3 Citations (Scopus)

Polymer particles as the carrier for affinity purification

Hatakeyama, M., Nishio, K., Nakamura, M., Sakamoto, S., Kabe, Y., Wada, T. & Handa, H., 2007 Jan, In : Kobunshi Ronbunshu. 64, 1, p. 9-20 12 p.

Research output: Contribution to journalArticle

Purification
purification
Polymers
polymer
ferrite
2 Citations (Scopus)

Strategy for chemical biology using affinity magnetic nanobeads

Kabe, Y. & Handa, H., 2007 Oct, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 52, 13 Suppl, p. 1637-1642 6 p.

Research output: Contribution to journalArticle

Antineoplastic Antimetabolites
Polymethacrylic Acids
Antineoplastic Combined Chemotherapy Protocols
Deoxycytidine Kinase
Affinity Labels
67 Citations (Scopus)

The Enteropathogenic E. coli Effector EspB Facilitates Microvillus Effacing and Antiphagocytosis by Inhibiting Myosin Function

Iizumi, Y., Sagara, H., Kabe, Y., Azuma, M., Kume, K., Ogawa, M., Nagai, T., Gillespie, P. G., Sasakawa, C. & Handa, H., 2007 Dec 13, In : Cell Host and Microbe. 2, 6, p. 383-392 10 p.

Research output: Contribution to journalArticle

Enteropathogenic Escherichia coli
Myosins
Microvilli
Phagocytosis
Citrobacter rodentium
2006
42 Citations (Scopus)

Porphyrin accumulation in mitochondria is mediated by 2-oxoglutarate carrier

Kabe, Y., Ohmori, M., Shinouchi, K., Tsuboi, Y., Hirao, S., Azuma, M., Watanabe, H., Okura, I. & Handa, H., 2006 Oct 20, In : Journal of Biological Chemistry. 281, 42, p. 31729-31735 7 p.

Research output: Contribution to journalArticle

Mitochondria
Porphyrins
Heme
Derivatives
Palladium
16 Citations (Scopus)

TFII-I down-regulates a subset of estrogen-responsive genes through its interaction with an initiator element and estrogen receptor α

Ogura, Y., Azuma, M., Tsuboi, Y., Kabe, Y., Yamaguchi, Y., Wada, T., Watanabe, H. & Handa, H., 2006 Apr, In : Genes to Cells. 11, 4, p. 373-381 9 p.

Research output: Contribution to journalArticle

Estrogen Receptors
Estrogens
Down-Regulation
General Transcription Factors
Co-Repressor Proteins
2005
41 Citations (Scopus)

GABP, HCF-1 and YY1 are involved in Rb gene expression during myogenesis

Deléhouzée, S., Yoshikawa, T., Sawa, C., Sawada, J. I., Ito, T., Omori, M., Wada, T., Yamaguchi, Y., Kabe, Y. & Handa, H., 2005 Jul, In : Genes to Cells. 10, 7, p. 717-731 15 p.

Research output: Contribution to journalArticle

Retinoblastoma Genes
Muscle Development
Up-Regulation
Gene Expression
GA-Binding Protein Transcription Factor
66 Citations (Scopus)

NF-Y is essential for the recruitment of RNA polymerase II and inducible transcription of several CCAAT box-containing genes

Kabe, Y., Yamada, J., Uga, H., Yamaguchi, Y., Wada, T. & Handa, H., 2005 Jan, In : Molecular and Cellular Biology. 25, 1, p. 512-522 11 p.

Research output: Contribution to journalArticle

RANK Ligand
RNA Polymerase II
TATA-Box Binding Protein
Genes
Cholecalciferol
353 Citations (Scopus)

Redox regulation of NF-κB activation: Distinct redox regulation between the cytoplasm and the nucleus

Kabe, Y., Ando, K., Hirao, S., Yoshida, M. & Handa, H., 2005 Mar, In : Antioxidants and Redox Signaling. 7, 3-4, p. 395-403 9 p.

Research output: Contribution to journalArticle

Oxidation-Reduction
Cytoplasm
Chemical activation
Oxidation
Signal transduction
2004
14 Citations (Scopus)

Design and synthesis of a solid-supported FR225659 derivative for its receptor screening

Zenkoh, T., Hatori, H., Tanaka, H., Hasegawa, M., Hatakeyama, M., Kabe, Y., Setoi, H., Kawaguchi, H., Handa, H. & Takahashi, T., 2004 Jul 8, In : Organic Letters. 6, 14, p. 2477-2480 4 p.

Research output: Contribution to journalArticle

Screening
screening
Latex
latex
activity (biology)

Screening of drug target receptor by using nanotechnology

Hatakeyama, M., Kabe, Y. & Handa, H., 2004, In : Drug Delivery System. 19, 2, p. 127-132 6 p.

Research output: Contribution to journalArticle

Drug Receptors
Nanotechnology
Affinity Chromatography
1999
13 Citations (Scopus)

Identification of the core domain and the secondary structure of the transcriptional coactivator MBF-1

Ozaki, J., Takemaru, K. I., Ikegami, T., Mishima, M., Ueda, H., Hirose, S., Kabe, Y., Handa, H. & Shirakawa, M., 1999, In : Genes to Cells. 4, 7, p. 415-424 10 p.

Research output: Contribution to journalArticle

TATA-Box Binding Protein
Protein Binding
DNA
Chymotrypsin
Transcriptional Activation
8 Citations (Scopus)

Resonance assignments, secondary structure and 15N relaxation data of the human transcriptional coactivator hMBF1 (57-148)

Mishima, M., Ozaki, J., Ikegami, T., Kabe, Y., Goto, M., Ueda, H., Hirose, S., Handa, H. & Shirakawa, M., 1999, In : Journal of Biomolecular NMR. 14, 4, p. 373-376 4 p.

Research output: Contribution to journalArticle

TATA-Box Binding Protein
Protein Binding
Cytoplasmic and Nuclear Receptors
Yeast
Chemical activation
66 Citations (Scopus)

The role of human MBF1 as a transcriptional coactivator

Kabe, Y., Goto, M., Shima, D., Imai, T., Wada, T., Morohashi, K. I., Shirakawa, M., Hirose, S. & Handa, H., 1999 Nov 26, In : Journal of Biological Chemistry. 274, 48, p. 34196-34202 7 p.

Research output: Contribution to journalArticle

Leucine Zippers
Transcriptional Activation
Protein Isoforms
Chemical activation
General Transcription Factors
1998
20 Citations (Scopus)

(+)-Rhododendrol and epi-rhododendrin suppress the no production by activated macrophages in vivo

Fushiya, S., Kabe, Y., Ikegaya, Y. & Takano, F., 1998, In : Planta Medica. 64, 7, p. 598-602 5 p.

Research output: Contribution to journalArticle

Macrophages
nitric oxide
Nitric Oxide
macrophages
Aceraceae