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Research Output

  • 2040 Citations
  • 19 h-Index
  • 77 Article
  • 8 Letter
  • 4 Comment/debate
  • 4 Review article
2020

Association of glucose tolerance status with pancreatic β- and α-cell mass in community-based autopsy samples of Japanese individuals: The Hisayama Study

Inaishi, J., Saisho, Y., Hirakawa, Y., Yoshida, D., Hata, J., Mukai, N., Watanabe, Y., Oda, Y., Itoh, H. & Ninomiya, T., 2020 Jan 1, (Accepted/In press) In : Journal of Diabetes Investigation.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Efficacy and safety of once-weekly exenatide after switching from twice-daily exenatide in patients with type 2 diabetes

for the Twin-exenatide Study Group, 2020 Mar 1, In : Journal of Diabetes Investigation. 11, 2, p. 382-388 7 p.

Research output: Contribution to journalArticle

Open Access

Pancreatic alpha-cell mass across adult human lifespan

Moin, A. S. M., Cory, M., Gurlo, T., Saisho, Y., Rizza, R. A., Butler, P. C. & Butler, A. E., 2020 Jan 1, In : European journal of endocrinology. 182, 2, p. 219-231 13 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2019

Cardiorenal Protection: Potential of SGLT2 Inhibitors and GLP-1 Receptor Agonists in the Treatment of Type 2 Diabetes

Nagahisa, T. & Saisho, Y., 2019 Jan 1, (Accepted/In press) In : Diabetes Therapy.

Research output: Contribution to journalReview article

6 Citations (Scopus)
1 Citation (Scopus)
Open Access

Glycemic and metabolic features in gestational diabetes: Singleton versus twin pregnancies

Akiba, Y., Miyakoshi, K., Ikenoue, S., Saisho, Y., Kasuga, Y., Ochiai, D., Matsumoto, T. & Tanaka, M., 2019 Jan 1, In : Endocrine journal. 66, 7, p. 647-651 5 p.

Research output: Contribution to journalComment/debate

Open Access
1 Citation (Scopus)

Usefulness of hemoglobin a1c and glycated albumin measurements for insulinoma screening: An observational case-control study

Torimoto, K., Okada, Y., Tanaka, Y., Matsuoka, A., Hirota, Y., Ogawa, W., Saisho, Y., Kurihara, I., Itoh, H., Inada, S. & Koga, M., 2019 Feb 26, In : BMC cancer. 19, 1, 174.

Research output: Contribution to journalArticle

Open Access
2018

Association between severity of obstructive sleep apnea and glycated hemoglobin level in japanese individuals with and without diabetes

Kurosawa, H., Saisho, Y., Fukunaga, K., Haraguchi, M., Yamasawa, W., Kurihara, I., Betsuyaku, T. & Itoh, H., 2018 Jan 1, In : Endocrine Journal. 65, 1, p. 121-127 7 p.

Research output: Contribution to journalComment/debate

4 Citations (Scopus)
1 Citation (Scopus)
1 Citation (Scopus)
1 Citation (Scopus)

Signaling between pancreatic cells and macrophages via S100 calcium-binding protein A8 exacerbates β-cell apoptosis and islet inflammation

Inoue, H., Shirakawa, J., Togashi, Y., Tajima, K., Okuyama, T., Kyohara, M., Tanaka, Y., Orime, K., Saisho, Y., Yamada, T., Shibue, K., Kulkarni, R. N. & Terauchi, Y., 2018 Apr 20, In : Journal of Biological Chemistry. 293, 16, p. 5934-5946 13 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
10 Citations (Scopus)

α- and β-cell mass

Yoshifumi, S., 2018 Jan 1, In : Journal of the Japan Diabetes Society. 61, 2, p. 48-50 3 p.

Research output: Contribution to journalArticle

2017

A case report of hyperosmolar hyperglycemic state in a 7-year-old child: An unusual presentation of first appearance of type 1 diabetes mellitus

Cho, Y. M., Park, B. S., Kang, M. J. & Saisho, Y., 2017 Jun 1, In : Medicine (United States). 96, 25, e7369.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Association of common polymorphisms with gestational diabetes mellitus in Japanese women: A case-control study

Kasuga, Y., Hata, K., Tajima, A., Ochiai, D., Saisho, Y., Matsumoto, T., Arata, N., Miyakoshi, K. & Tanaka, M., 2017, In : Endocrine Journal. 64, 4, p. 463-475 13 p.

Research output: Contribution to journalComment/debate

5 Citations (Scopus)

Pancreas Fat and β Cell Mass in Humans With and Without Diabetes: An Analysis in the Japanese Population

Murakami, R., Saisho, Y., Watanabe, Y., Inaishi, J., Tsuchiya, T., Kou, K., Sato, S., Kitago, M., Kitagawa, Y., Yamada, T. & Itoh, H., 2017 Sep 1, In : The Journal of clinical endocrinology and metabolism. 102, 9, p. 3251-3260 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2016

Effects of obesity and diabetes on α-and β-cell mass in surgically resected human pancreas

Inaishi, J., Saisho, Y., Sato, S., Kou, K., Murakami, R., Watanabe, Y., Kitago, M., Kitagawa, Y., Yamada, T. & Itoh, H., 2016 Jul 1, In : Journal of Clinical Endocrinology and Metabolism. 101, 7, p. 2863-2873 11 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)
12 Citations (Scopus)
19 Citations (Scopus)

The pancreas in humans with and without diabetes

Saisho, Y., 2016 Apr 1, In : Diabetologia. 59, 4, p. 868-869 2 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
6 Citations (Scopus)
2015

Alogliptin benzoate for management of type 2 diabetes

Saisho, Y., 2015 Apr 10, In : Vascular Health and Risk Management. 11, p. 229-243 15 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

A reduction of HbAs1c after 3 months predicts 2-year responsiveness to sitagliptin treatment

Nishimura, T., Meguro, S., Sekioka, R., Tanaka, K., Saisho, Y., Irie, J., Tanaka, M., Kawai, T. & Itoh, H., 2015 Dec 1, In : Internal Medicine. 54, 23, p. 2981-2989 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
4 Citations (Scopus)

Effects of Glucocorticoid Treatment on β- and α-Cell Mass in Japanese Adults With and Without Diabetes

Sato, S., Saisho, Y., Inaishi, J., Kou, K., Murakami, R., Yamada, T. & Itoh, H., 2015 Aug 1, In : Diabetes. 64, 8, p. 2915-2927 13 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
7 Citations (Scopus)

Efficacy and safety of liraglutide monotherapy compared with metformin in Japanese overweight/obese patients with type 2 diabetes

Tanaka, K., Saisho, Y., Kawai, T., Tanaka, M., Meguro, S., Irie, J., Imai, T., Shigihara, T., Morimoto, J., Yajima, K., Atsumi, Y., Takei, I. & Itoh, H., 2015 Jan 1, In : Endocrine journal. 62, 5, p. 399-409 11 p.

Research output: Contribution to journalArticle

Open Access
19 Citations (Scopus)

Efficacy and safety of sitagliptin added to insulin in Japanese patients with type 2 Diabetes: The EDIT randomized trial

Sato, S., Saisho, Y., Kou, K., Meguro, S., Tanaka, M., Irie, J., Kawai, T. & Itoh, H., 2015 Mar 27, In : PloS one. 10, 3, e0121988.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Metformin and inflammation: Its potential beyond glucose-lowering effect

Saisho, Y., 2015 Sep 1, In : Endocrine, Metabolic and Immune Disorders - Drug Targets. 15, 3, p. 196-205 10 p.

Research output: Contribution to journalArticle

131 Citations (Scopus)

Relationships among different glycemic variability indices obtained by continuous glucose monitoring

Saisho, Y., Tanaka, C., Tanaka, K., Roberts, R., Abe, T., Tanaka, M., Meguro, S., Irie, J., Kawai, T. & Itoh, H., 2015 Aug 1, In : Primary Care Diabetes. 9, 4, p. 290-296 7 p., 424.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Serum C-peptide to plasma glucose ratio may be associated with efficacy of vildagliptin in Japanese patients with type 2 diabetes mellitus

Tanaka, M., Sekioka, R., Nishimura, T., Kawai, T., Meguro, S., Irie, J., Saisho, Y. & Itoh, H., 2015 Sep 4, In : Diabetology International. 6, 3, p. 197-205 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2014

Clinical impact of women with gestational diabetes mellitus by the new consensus criteria: Two year experience in a single institution in Japan

Ikenoue, S., Miyakoshi, K., Saisho, Y., Sakai, K., Kasuga, Y., Fukutake, M., Izumi, Y., Matsumoto, T., Minegishi, K. & Yoshimura, Y., 2014, In : Endocrine journal. 61, 4, p. 353-358 6 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
7 Citations (Scopus)

Efficacy and Safety of alogliptin administered to 219 type 2 diabetic patients for 12 months

Nishimura, T., Tanaka, M., Sekioka, R., Kawai, T., Meguro, S., Irie, J., Saisho, Y. & Itoh, H., 2014, In : Japanese Pharmacology and Therapeutics. 42, 7, p. 495-501 7 p.

Research output: Contribution to journalArticle

Factors associated with glycemic variability in Japanese patients with diabetes

Tanaka, C., Saisho, Y., Tanaka, K., Kou, K., Tanaka, M., Meguro, S., Irie, J., Jo, R., Kawai, T. & Itoh, H., 2014 Jan 1, In : Diabetology International. 5, 1, p. 36-42 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Glycemic variability and oxidative stress: A link between diabetes and cardiovascular disease?

Saisho, Y., 2014 Oct 13, In : International journal of molecular sciences. 15, 10, p. 18381-18406 26 p.

Research output: Contribution to journalReview article

66 Citations (Scopus)

Islet number rather than islet size is a major determinant of α- And β-Cell mass in humans

Kou, K., Saisho, Y., Sato, S., Yamada, T. & Itoh, H., 2014 May, In : Journal of Clinical Endocrinology and Metabolism. 99, 5, p. 1733-1740 8 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Lower beta cell function relates to sustained higher glycated albumin to glycated hemoglobin ratio in Japanese patients with type 2 diabetes

Saisho, Y., Tanaka, K., Abe, T., Kawai, T. & Itoh, H., 2014 Mar 6, In : Endocrine journal. 61, 2, p. 149-157 9 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Pancreas volume with obesity in asians: Comparison with whites

Saisho, Y., 2014 May, In : Pancreas. 43, 4, p. 657-659 3 p.

Research output: Contribution to journalLetter

7 Citations (Scopus)

Relationship between body mass index and pancreas volume in japanese adults

Kou, K., Saisho, Y., Jinzaki, M. & Itoh, H., 2014 Jan 1, In : Journal of the Pancreas. 15, 6, p. 626-627 2 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2013
8 Citations (Scopus)

Association between beta cell function and future glycemic control in patients with type 2 diabetes

Saisho, Y., Kou, K., Tanaka, K., Abe, T., Shimada, A., Kawai, T. & Itoh, H., 2013 May 7, In : Endocrine journal. 60, 4, p. 517-523 7 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Change in cell mass in japanese nondiabetic Obese individuals

Kou, K., Saisho, Y., Satoh, S., Yamada, T. & Itoh, H., 2013 Sep 1, In : Journal of Clinical Endocrinology and Metabolism. 98, 9, p. 3724-3730 7 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)
12 Citations (Scopus)

Dipeptidyl peptidase-4 inhibitors and angioedema: A class effect?

Saisho, Y. & Itoh, H., 2013 Apr, In : Diabetic Medicine. 30, 4, p. e149-e150

Research output: Contribution to journalArticle

9 Citations (Scopus)
9 Citations (Scopus)