• 7667 Citations
  • 48 h-Index
1979 …2020
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Research Output 1979 2020

  • 7667 Citations
  • 48 h-Index
  • 205 Article
2020

pH-dependent transport kinetics of the human organic anion-transporting polypeptide 1A2

Morita, T., Akiyoshi, T., Sato, R., Katayama, K., Yajima, K., Kataoka, H., Imaoka, A., Sugimoto, Y. & Ohtani, H., 2020 Jan 1, (Accepted/In press) In : Drug Metabolism And Pharmacokinetics.

Research output: Contribution to journalArticle

Anions
Peptides
HEK293 Cells
Binding Sites
Intestinal Absorption
2019
1 Citation (Scopus)

Collateral sensitivity of drug-resistant ABCB5- and mutation-activated EGFR overexpressing cells towards resveratrol due to modulation of SIRT1 expression

Saeed, M. E. M., Rahama, M., Kuete, V., Dawood, M., Elbadawi, M., Sugimoto, Y. & Efferth, T., 2019 Jun 1, In : Phytomedicine. 59, 152890.

Research output: Contribution to journalArticle

Sirtuin 1
Mutation
Pharmaceutical Preparations
Multiple Drug Resistance
Cluster Analysis
2 Citations (Scopus)

Cytotoxicity of 40 Egyptian plant extracts targeting mechanisms of drug-resistant cancer cells

Hegazy, M. E. F., Abdelfatah, S., Hamed, A. R., Mohamed, T. A., Elshamy, A. A., Saleh, I. A., Reda, E. H., Abdel-Azim, N. S., Shams, K. A., Sakr, M., Sugimoto, Y., Paré, P. W. & Efferth, T., 2019 Jun 1, In : Phytomedicine. 59, 152771.

Research output: Contribution to journalArticle

Plant Extracts
Drug Delivery Systems
Centaurea
Multiple Drug Resistance
Pulicaria
2 Citations (Scopus)

Cytotoxicity of cucurbitacin E from Citrullus colocynthis against multidrug-resistant cancer cells

Saeed, M. E. M., Boulos, J. C., Elhaboub, G., Rigano, D., Saab, A., Loizzo, M. R., Hassan, L. E. A., Sugimoto, Y., Piacente, S., Tundis, R., Yagi, S., Khalid, H. & Efferth, T., 2019 Sep 1, In : Phytomedicine. 62, 152945.

Research output: Contribution to journalArticle

Neoplasms
P-Glycoprotein
Cucurbitacins
Epidermal Growth Factor Receptor
Breast Neoplasms

Novel pharmacological effects of poly (ADP-ribose) polymerase inhibitor rucaparib on the lactate dehydrogenase pathway

Nonomiya, Y., Noguchi, K., Katayama, K. & Sugimoto, Y., 2019 Mar 19, In : Biochemical and Biophysical Research Communications. 510, 4, p. 501-507 7 p.

Research output: Contribution to journalArticle

L-Lactate Dehydrogenase
Pharmacology
Ovarian Neoplasms
Repair
DNA Repair-Deficiency Disorders
2 Citations (Scopus)

Regorafenib-Induced Hand-Foot Skin Reaction Is More Severe on the Feet Than on the Hands

Nonomiya, Y., Yokokawa, T., Kawakami, K., Kobayashi, K., Aoyama, T., Takiguchi, T., Sugisaki, T., Suzuki, K., Suenaga, M., Wakatsuki, T., Yamaguchi, K., Sugimoto, Y. & Hama, T., 2019 May 7, In : Oncology research. 27, 5, p. 551-556 6 p.

Research output: Contribution to journalArticle

Foot
Hand
Skin
regorafenib
Colorectal Neoplasms

SNAIL- and SLUG-induced side population phenotype of HCT116 human colorectal cancer cells and its regulation by BET inhibitors

Kato, Y., Kondo, S., Itakura, T., Tokunaga, M., Hatayama, S., Katayama, K. & Sugimoto, Y., 2019 Jan 1, (Accepted/In press) In : Biochemical and Biophysical Research Communications.

Research output: Contribution to journalArticle

irinotecan
Side-Population Cells
Epithelial-Mesenchymal Transition
Colorectal Neoplasms
Cells
2018
Protein-Tyrosine Kinases
Phosphotransferases
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Physiological Stress
Endoplasmic Reticulum
6 Citations (Scopus)

Betulinic acid exerts cytotoxic activity against multidrug-resistant tumor cells via targeting autocrine motility factor receptor (AMFR)

Saeed, M. E. M., Mahmoud, N., Sugimoto, Y., Efferth, T. & Abdel-Aziz, H., 2018 May 15, In : Frontiers in Pharmacology. 9, MAY, 481.

Research output: Contribution to journalArticle

Autocrine Motility Factor Receptor
Neoplasms
National Cancer Institute (U.S.)
Pentacyclic Triterpenes
Pharmaceutical Preparations

Cell-based chemical fingerprinting identifies telomeres and lamin A as modifiers of DNA damage response in cancer cells

Fujiwara, C., Muramatsu, Y., Nishii, M., Tokunaka, K., Tahara, H., Ueno, M., Yamori, T., Sugimoto, Y. & Seimiya, H., 2018 Dec 1, In : Scientific Reports. 8, 1, 14827.

Research output: Contribution to journalArticle

Lamin Type A
Telomere
DNA Damage
Telomerase
Neoplasms
2 Citations (Scopus)

Cytotoxicity of nimbolide towards multidrug-resistant tumor cells and hypersensitivity via cellular metabolic modulation

Mahmoud, N., Saeed, M. E. M., Sugimoto, Y., Klauck, S. M., Greten, H. J. & Efferth, T., 2018 Nov 1, In : Oncotarget. 9, 87, p. 35762-35779 18 p.

Research output: Contribution to journalArticle

Hypersensitivity
Neoplasms
Multiple Drug Resistance
P-Glycoprotein
Epidermal Growth Factor Receptor
4 Citations (Scopus)

Cytotoxicity of sesquiterpene alkaloids from Nuphar plants toward sensitive and drug-resistant cell lines

Fukaya, M., Nakamura, S., Hegazy, M. E. F., Sugimoto, Y., Hayashi, N., Nakashima, S., Yoshikawa, M., Efferth, T. & Matsuda, H., 2018 Dec 13, In : Food & function. 9, 12, p. 6279-6286 8 p.

Research output: Contribution to journalArticle

Nuphar
Sesquiterpenes
Alkaloids
sesquiterpenoids
cytotoxicity
2 Citations (Scopus)

Heat shock protein 90 inhibitors overcome the resistance to Fms-like tyrosine kinase 3 inhibitors in acute myeloid leukemia

Katayama, K., Noguchi, K. & Sugimoto, Y., 2018 Sep 1, In : Oncotarget. 9, 76, p. 34240-34258 19 p.

Research output: Contribution to journalArticle

fms-Like Tyrosine Kinase 3
HSP90 Heat-Shock Proteins
Acute Myeloid Leukemia
4'-N-benzoylstaurosporine
Protein-Tyrosine Kinases
1 Citation (Scopus)

IL-10 promoter transactivation by the viral K-RTA protein involves the host-cell transcription factors, specificity proteins 1 and 3

Miyazawa, M., Noguchi, K., Kujirai, M., Katayama, K., Yamagoe, S. & Sugimoto, Y., 2018 Jan 12, In : Journal of Biological Chemistry. 293, 2, p. 662-676 15 p.

Research output: Contribution to journalArticle

Sp3 Transcription Factor
Sp1 Transcription Factor
Human Herpesvirus 8
Transcription
Interleukin-10
5 Citations (Scopus)

Molecular determinants of sensitivity or resistance of cancer cells toward sanguinarine

Saeed, M. E. M., Mahmoud, N., Sugimoto, Y., Efferth, T. & Abdel-Aziz, H., 2018 Feb 26, In : Frontiers in Pharmacology. 9, FEB, 136.

Research output: Contribution to journalArticle

Drug Resistance
Neoplasms
Epidermal Growth Factor Receptor
Benzophenanthridines
ATP-Binding Cassette Transporters
1 Citation (Scopus)

Protein kinase C alpha-mediated phosphorylation of PIM-1L promotes the survival and proliferation of acute myeloid leukemia cells

Takami, M., Katayama, K., Noguchi, K. & Sugimoto, Y., 2018 Jan 1, (Accepted/In press) In : Biochemical and Biophysical Research Communications.

Research output: Contribution to journalArticle

Protein Kinase C-alpha
Phosphorylation
Myeloid Cells
Acute Myeloid Leukemia
Protein-Tyrosine Kinases
4 Citations (Scopus)

Repurposing of bromocriptine for cancer therapy

Seo, E. J., Sugimoto, Y., Greten, H. J. & Efferth, T., 2018 Oct 8, In : Frontiers in Pharmacology. 9, OCT, 1030.

Research output: Contribution to journalArticle

Bromocriptine
Neoplasms
Therapeutics
Pharmaceutical Preparations
Cell Line
Drug Resistance
Protein Binding
Adenosine Triphosphate
irinotecan
Breast Neoplasms
2017
20 Citations (Scopus)

APC mutations as a potential biomarker for sensitivity to tankyrase inhibitors in colorectal cancer

Tanaka, N., Mashima, T., Mizutani, A., Sato, A., Aoyama, A., Gong, B., Yoshida, H., Muramatsu, Y., Nakata, K., Matsuura, M., Katayama, R., Nagayama, S., Fujita, N., Sugimoto, Y. & Seimiya, H., 2017 Apr 1, In : Molecular Cancer Therapeutics. 16, 4, p. 752-762 11 p.

Research output: Contribution to journalArticle

Tankyrases
Catenins
Adenomatous Polyposis Coli
Colorectal Neoplasms
Biomarkers
2 Citations (Scopus)

Functional effects of AKT3 on aurora kinase inhibitorinduced aneuploidy

Noguchi, K., Hongama, K., Hariki, S., Nonomiya, Y., Katayama, K. & Sugimoto, Y., 2017 Feb 3, In : Journal of Biological Chemistry. 292, 5, p. 1910-1924 15 p.

Research output: Contribution to journalArticle

Aurora Kinases
Aneuploidy
HCT116 Cells
Anaphase
Phosphorylation
7 Citations (Scopus)

mTOR signaling mediates resistance to tankyrase inhibitors in Wnt-driven colorectal cancer

Mashima, T., Taneda, Y., Jang, M. K., Mizutani, A., Muramatsu, Y., Yoshida, H., Sato, A., Tanaka, N., Sugimoto, Y. & Seimiya, H., 2017, In : Oncotarget. 8, 29, p. 47902-47915 14 p.

Research output: Contribution to journalArticle

Tankyrases
Catenins
Colorectal Neoplasms
Cell Line
Poly(ADP-ribose) Polymerases
2016
5 Citations (Scopus)

Effect of AKT3 expression on MYC- and caspase-8-dependent apoptosis caused by polo-like kinase inhibitors in HCT 116 cells

Nonomiya, Y., Noguchi, K., Tanaka, N., Kasagaki, T., Katayama, K. & Sugimoto, Y., 2016 Dec 1, In : Cancer Science. 107, 12, p. 1877-1887 11 p.

Research output: Contribution to journalArticle

HCT116 Cells
Caspase 8
P-Glycoprotein
Phosphotransferases
Apoptosis
8 Citations (Scopus)

RSK1 protects P-glycoprotein/ABCB1 against ubiquitin-proteasomal degradation by downregulating the ubiquitin-conjugating enzyme E2 R1

Katayama, K., Fujiwara, C., Noguchi, K. & Sugimoto, Y., 2016 Oct 27, In : Scientific Reports. 6, 36134.

Research output: Contribution to journalArticle

Ubiquitin-Conjugating Enzymes
P-Glycoprotein
Ubiquitin
Down-Regulation
Ubiquitination
2015
47 Citations (Scopus)

Activity of the dietary flavonoid, apigenin, against multidrug-resistant tumor cells as determined by pharmacogenomics and molecular docking

Saeed, M., Kadioglu, O., Khalid, H., Sugimoto, Y. & Efferth, T., 2015, In : Journal of Nutritional Biochemistry. 26, 1, p. 44-56 13 p.

Research output: Contribution to journalArticle

Apigenin
Pharmacogenetics
Flavonoids
Tumors
Cells
17 Citations (Scopus)

Cytotoxicity of 35 medicinal plants from Sudan towards sensitive and multidrug-resistant cancer cells

Saeed, M. E. M., Abdelgadir, H., Sugimoto, Y., Khalid, H. E. & Efferth, T., 2015 Apr 1, In : Journal of Ethnopharmacology. 174, p. 644-658 15 p.

Research output: Contribution to journalArticle

Sudan
Medicinal Plants
Neoplasms
Complex Mixtures
Ambrosia
13 Citations (Scopus)

Cytotoxicity of the sesquiterpene lactones neoambrosin and damsin from Ambrosia maritima against multidrug-resistant cancer cells

Saeed, M., Jacob, S., Sandjo, L. P., Sugimoto, Y., Khalid, H. E., Opatz, T., Thines, E. & Efferth, T., 2015, In : Frontiers in Pharmacology. 6, NOV, 267.

Research output: Contribution to journalArticle

Ambrosia
Sesquiterpenes
Lactones
ATP-Binding Cassette Transporters
Immunoblotting
3 Citations (Scopus)

Upregulation of cellular glutathione levels in human ABCB5- and murine Abcb5-transfected cells

Kondo, S., Hongama, K., Hanaya, K., Yoshida, R., Kawanobe, T., Katayama, K., Noguchi, K. & Sugimoto, Y., 2015 Dec 15, In : BMC Pharmacology and Toxicology. 16, 1, 37.

Research output: Contribution to journalArticle

Glutathione
Up-Regulation
Buthionine Sulfoximine
Ligases
Enzymes
2014
114 Citations (Scopus)
ATP-Binding Cassette Transporters
irinotecan
Breast Neoplasms
Neoplasms
Proteins
14 Citations (Scopus)

Protein phosphatase complex PP5/PPP2R3C dephosphorylates P-glycoprotein/ABCB1 and down-regulates the expression and function

Katayama, K., Yamaguchi, M., Noguchi, K. & Sugimoto, Y., 2014 Apr 1, In : Cancer Letters. 345, 1, p. 124-131 8 p.

Research output: Contribution to journalArticle

Phosphoprotein Phosphatases
P-Glycoprotein
Down-Regulation
Protein Phosphatase 2
Multiple Drug Resistance
5 Citations (Scopus)

Resistance mechanisms of cancer cells to the novel vacuolar H(+)-ATPase inhibitor archazolid B

Hamm, R., Sugimoto, Y., Steinmetz, H. & Efferth, T., 2014 Oct 1, In : Investigational New Drugs. 32, 5, p. 893-903 11 p.

Research output: Contribution to journalArticle

Vacuolar Proton-Translocating ATPases
Neoplasms
P-Glycoprotein
Drug Resistance
archazolid B
17 Citations (Scopus)

The lignan, (-)-sesamin reveals cytotoxicity toward cancer cells: Pharmacogenomic determination of genes associated with sensitivity or resistance

Saeed, M., Khalid, H., Sugimoto, Y. & Efferth, T., 2014 Apr 15, In : Phytomedicine. 21, 5, p. 689-696 8 p.

Research output: Contribution to journalArticle

Lignans
Pharmacogenetics
Multiple Drug Resistance
Genes
Neoplasms
2013
14 Citations (Scopus)

Biochemical interaction of anti-HCV telaprevir with the ABC transporters P-glycoprotein and breast cancer resistance protein

Fujita, Y., Noguchi, K., Suzuki, T., Katayama, K. & Sugimoto, Y., 2013, In : BMC Research Notes. 6, 1, 445.

Research output: Contribution to journalArticle

ATP-Binding Cassette Transporters
P-Glycoprotein
Viruses
Hepacivirus
Breast Neoplasms
22 Citations (Scopus)

FBXO15 regulates P-glycoprotein/ABCB1 expression through the ubiquitin-proteasome pathway in cancer cells

Katayama, K., Noguchi, K. & Sugimoto, Y., 2013 Jun, In : Cancer Science. 104, 6, p. 694-702 9 p.

Research output: Contribution to journalArticle

P-Glycoprotein
Proteasome Endopeptidase Complex
Ubiquitin
Ubiquitination
Neoplasms
2012
33 Citations (Scopus)

Expression of human ABCB5 confers resistance to taxanes and anthracyclines

Kawanobe, T., Kogure, S., Nakamura, S., Sato, M., Katayama, K., Mitsuhashi, J., Noguchi, K. & Sugimoto, Y., 2012 Feb 24, In : Biochemical and Biophysical Research Communications. 418, 4, p. 736-741 6 p.

Research output: Contribution to journalArticle

docetaxel
Taxoids
Anthracyclines
Adenosine Triphosphatases
ATP-Binding Cassette Transporters
2011
21 Citations (Scopus)

DNA ligand designed to antagonize EBNA1 represses Epstein-Barr virus-induced immortalization

Yasuda, A., Noguchi, K., Minoshima, M., Kashiwazaki, G., Kanda, T., Katayama, K., Mitsuhashi, J., Bando, T., Sugiyama, H. & Sugimoto, Y., 2011 Dec, In : Cancer Science. 102, 12, p. 2221-2230 10 p.

Research output: Contribution to journalArticle

Human Herpesvirus 4
Replication Origin
Plasmids
Ligands
DNA
33 Citations (Scopus)

Novel acrylonitrile derivatives, YHO-13177 and YHO-13351, reverse BCRP/ABCG2-mediated drug resistance in vitro and in vivo

Yamazaki, R., Nishiyama, Y., Furuta, T., Hatano, H., Igarashi, Y., Asakawa, N., Kodaira, H., Takahashi, H., Aiyama, R., Matsuzaki, T., Yagi, N. & Sugimoto, Y., 2011 Jul, In : Molecular Cancer Therapeutics. 10, 7, p. 1252-1263 12 p.

Research output: Contribution to journalArticle

irinotecan
Acrylonitrile
Drug Resistance
Topotecan
Mitoxantrone
4 Citations (Scopus)

Novel regulatory role for Kaposi's sarcoma-associated herpesvirus-encoded vFLIP in chemosensitization to bleomycin

Masuda, Y., Noguchi, K., Segawa, H., Tanaka, N., Katayama, K., Mitsuhashi, J. & Sugimoto, Y., 2011 Nov 18, In : Biochemical and Biophysical Research Communications. 415, 2, p. 305-312 8 p.

Research output: Contribution to journalArticle

Human Herpesvirus 8
Bleomycin
Response Elements
DNA Damage
CASP8 and FADD-Like Apoptosis Regulating Protein
2010
30 Citations (Scopus)

A novel yeast cell-based screen identifies flavone as a tankyrase inhibitor

Yashiroda, Y., Okamoto, R., Hatsugai, K., Takemoto, Y., Goshima, N., Saito, T., Hamamoto, M., Sugimoto, Y., Osada, H., Seimiya, H. & Yoshida, M., 2010 Apr 9, In : Biochemical and Biophysical Research Communications. 394, 3, p. 569-573 5 p.

Research output: Contribution to journalArticle

flavone
Tankyrases
Yeast
Yeasts
Cells
15 Citations (Scopus)

BCRP/ABCG2 confers anticancer drug resistance without covalent dimerization

Shigeta, J., Katayama, K., Mitsuhashi, J., Noguchi, K. & Sugimoto, Y., 2010 Aug, In : Cancer Science. 101, 8, p. 1813-1821 9 p.

Research output: Contribution to journalArticle

Dimerization
Drug Resistance
Mitoxantrone
Multiple Drug Resistance
Polyacrylamide Gel Electrophoresis
31 Citations (Scopus)

Breast cancer resistant protein (BCRP) is a molecular determinant of the outcome of photodynamic therapy (PDT) for centrally located early lung cancer

Usuda, J., Tsunoda, Y., Ichinose, S., Ishizumi, T., Ohtani, K., Maehara, S., Ono, S., Tsutsui, H., Ohira, T., Okunaka, T., Furukawa, K., Sugimoto, Y., Kato, H. & Ikeda, N., 2010 Feb, In : Lung Cancer. 67, 2, p. 198-204 7 p.

Research output: Contribution to journalArticle

Photochemotherapy
Lung Neoplasms
Breast Neoplasms
Dihematoporphyrin Ether
Proteins
3 Citations (Scopus)

Functional availability of γ-herpesvirus K-cyclin is regulated by cellular CDK6 and p16INK4a

Yoshioka, H., Noguchi, K., Katayama, K., Mitsuhashi, J., Yamagoe, S., Fujimuro, M. & Sugimoto, Y., 2010 Apr 16, In : Biochemical and Biophysical Research Communications. 394, 4, p. 1000-1005 6 p.

Research output: Contribution to journalArticle

Cyclins
Herpesviridae
Availability
Primary Effusion Lymphoma
Cyclin D
2 Citations (Scopus)

In vivo expansion of MDR1-transduced cells accompanied by a post-transplantation chemotherapy regimen with mitomycin C and methotrexate

Mitsuhashi, J., Hosoyama, H., Tsukahara, S., Katayama, K., Noguchi, K., Ito, Y., Hatake, K., Aiba, K., Takahashi, S. & Sugimoto, Y., 2010 Jul, In : Journal of Gene Medicine. 12, 7, p. 596-603 8 p.

Research output: Contribution to journalArticle

Multiple Drug Resistance
Mitomycin
Methotrexate
Transplantation
Drug Therapy
24 Citations (Scopus)

Pharmacological interaction with sunitinib is abolished by a germ-line mutation (1291T>C) of BCRP/ABCG2 gene

Kawahara, H., Noguchi, K., Katayama, K., Mitsuhashi, J. & Sugimoto, Y., 2010 Jun, In : Cancer Science. 101, 6, p. 1493-1500 8 p.

Research output: Contribution to journalArticle

Germ-Line Mutation
Pharmacology
Breast Neoplasms
Proteins
P-Glycoprotein
4 Citations (Scopus)

Tankyrase-1 assembly to large protein complexes blocks its telomeric function

Hatsugai, K., Ohishi, T., Sugimoto, Y. & Seimiya, H., 2010, In : FEBS Letters. 584, 18, p. 3885-3890 6 p.

Research output: Contribution to journalArticle

Tankyrases
Telomere
Proteins
Telomere-Binding Proteins
Protein Multimerization
2009
36 Citations (Scopus)

Acyl-CoA synthetase as a cancer survival factor: Its inhibition enhances the efficacy of etoposide

Mashima, T., Sato, S., Okabe, S., Miyata, S., Matsuura, M., Sugimoto, Y., Tsuruo, T. & Seimiya, H., 2009, In : Cancer Science. 100, 8, p. 1556-1562 7 p.

Research output: Contribution to journalArticle

Coenzyme A Ligases
Etoposide
Neoplasms
Apoptosis
Glioma
17 Citations (Scopus)

CMC-544 (inotuzumab ozogamicin), an anti-CD22 immuno-conjugate of calicheamicin, alters the levels of target molecules of malignant B-cells

Takeshita, A., Yamakage, N., Shinjo, K., Ono, T., Hirano, I., Nakamura, S., Shigeno, K., Tobita, T., Maekawa, M., Kiyoi, H., Naoe, T., Ohnishi, K., Sugimoto, Y. & Ohno, R., 2009, In : Leukemia. 23, 7, p. 1329-1336 8 p.

Research output: Contribution to journalArticle

B-Lymphocytes
Antibodies
Inotuzumab Ozogamicin
Neoplasms
Rituximab
39 Citations (Scopus)

CMC-544 (inotuzumab ozogamicin) shows less effect on multidrug resistant cells: Analyses in cell lines and cells from patients with B-cell chronic lymphocytic leukaemia and lymphoma

Takeshita, A., Shinjo, K., Yamakage, N., Ono, T., Hirano, I., Matsui, H., Shigeno, K., Nakamura, S., Tobita, T., Maekawa, M., Ohnishi, K., Sugimoto, Y., Kiyoi, H., Naoe, T. & Ohno, R., 2009 Jul, In : British Journal of Haematology. 146, 1, p. 34-43 10 p.

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
P-Glycoprotein
Cell Line
Non-Hodgkin's Lymphoma
Rhodamine 123
57 Citations (Scopus)

Dofequidar fumarate sensitizes cancer stem-like side population cells to chemotherapeutic drugs by inhibiting ABCG2/BCRP-mediated drug export

Katayama, R., Koike, S., Sato, S., Sugimoto, Y., Tsuruo, T. & Fujita, N., 2009 Nov, In : Cancer Science. 100, 11, p. 2060-2068 9 p.

Research output: Contribution to journalArticle

irinotecan
Side-Population Cells
Fumarates
Breast Neoplasms
Pharmaceutical Preparations
1 Citation (Scopus)

Erratum: CMC-544 (inotuzumab ozogamicin), an anti-CD22 immuno-conjugate of calicheamicin, alters the levels of target molecules of malignant B-cells (Leukemia (2009) vol. 23 (1329-1336) 10.1038/leukemia.2009.77)

Takeshita, A., Yamakage, N., Shinjo, K., Ono, T., Hirano, I., Nakamura, S., Shigeno, K., Tobita, T., Maekawa, M., Kiyoi, H., Naoe, T., Ohnishi, K., Sugimoto, Y. & Ohno, R., 2009, In : Leukemia. 23, 7, p. 1372 1 p.

Research output: Contribution to journalArticle

B-Cell Leukemia
Inotuzumab Ozogamicin
94 Citations (Scopus)

Functions of the breast cancer resistance protein (BCRP/ABCG2) in chemotherapy

Noguchi, K., Katayama, K., Mitsuhashi, J. & Sugimoto, Y., 2009 Jan 31, In : Advanced Drug Delivery Reviews. 61, 1, p. 26-33 8 p.

Research output: Contribution to journalArticle

Single Nucleotide Polymorphism
irinotecan
Breast Neoplasms
Drug Therapy
Topotecan