If you made any changes in Pure these will be visible here soon.

Research Output 1985 2016

  • 682 Citations
  • 14 h-Index
  • 48 Article
  • 1 Comment/debate
2016

Evaluation of the total antioxidant effect of complex-type supplements

Itoh, Y., Hiraide, S., Hoshino, Y., Shigeta, M. & Kanazawa, H., 2016, In : Bunseki Kagaku. 65, 9, p. 519-526 8 p.

Research output: Contribution to journalComment/debate

Antioxidants
Liquid chromatography
Chemical analysis
Nutrients
Health

Rapid and simultaneous analysis of psychotropic drugs by ultra-high-speed HPLC

Yoshikawa, M., Uchida, R., Kuroki, T., Mikuma, T., Hiruta, Y., Itoh, Y. & Kanazawa, I., 2016 May 10, In : Bunseki Kagaku. 65, 4, p. 173-179 7 p.

Research output: Contribution to journalArticle

Psychotropic Drugs
Pharmaceutical Preparations
Health care
Antidepressive Agents
Trazodone
2015

Correlation of physicochemical property and the dissolution behavior of ingredients of an antihypertensive combination tablet

Itoh, Y., Anan, Y. & Kanazawa, H., 2015 Dec 9, In : Bunseki Kagaku. 64, 11, p. 835-844 10 p.

Research output: Contribution to journalArticle

Antihypertensive Agents
Tablets
Dissolution
Amlodipine
High performance liquid chromatography
2014

Rapid quantitative analysis of multi-component supplements for antioxidation using ultra high-speed LC

Hiraide, S., Hoshino, Y., Shigeta, M., Kageyama, D., Kanazawa, H. & Itoh, Y., 2014 Sep 6, In : Bunseki Kagaku. 63, 8, p. 679-685 7 p.

Research output: Contribution to journalArticle

Health
Chemical analysis
Polyphenols
Vitamin E
Derivatives
2013
Liquid chromatography
Photodiodes
Antihypertensive Agents
Tablets
Detectors

Rapid and simultaneous analysis of oral antidiabetic drug by ultra-high-speed HPLC

Emoto, Y., Ishikawa, K., Ito, H., Hiraide, S., Itoh, Y. & Kanazawa, H., 2013, In : Bunseki Kagaku. 62, 8, p. 725-730 6 p.

Research output: Contribution to journalArticle

Hypoglycemic Agents
Medical problems
Insulin
pioglitazone
Drug Combinations
2012

Dissolution Tests of Loxoprofen Sodium Hydrate Tablets Using Ultra High-Speed Liquid Chromatography

Miura, Y., Itoh, Y. & Kanazawa, H., 2012, In : Bunseki Kagaku. 61, 8, p. 713-718 6 p.

Research output: Contribution to journalArticle

Liquid chromatography
Hydrates
Tablets
Dissolution
Generic Drugs
2011
7 Citations (Scopus)
Nitrogen Oxides
Tocopherols
Liquid chromatography
High Pressure Liquid Chromatography
Monitoring
2008
49 Citations (Scopus)

Aqueous chromatographic system for separation of biomolecules using thermoresponsive polymer modified stationary phase

Kanazawa, H., Nishikawa, M., Mizutani, A., Sakamoto, C., Morita-Murase, Y., Itoh, Y., Kikuchi, A. & Okano, T., 2008 May 16, In : Journal of Chromatography A. 1191, 1-2, p. 157-161 5 p.

Research output: Contribution to journalArticle

Biomolecules
Polymers
Temperature
Chromatography
Hydrophobic and Hydrophilic Interactions
2007
23 Citations (Scopus)

Analysis of melatonin using a pH- and temperature-responsive aqueous chromatography system

Ayano, E., Suzuki, Y., Kanezawa, M., Sakamoto, C., Morita-Murase, Y., Itoh, Y., Kanazawa, H., Kikuchi, A. & Okano, T., 2007 Jul 13, In : Journal of Chromatography A. 1156, 1-2 SPEC. ISS., p. 213-219 7 p.

Research output: Contribution to journalArticle

Melatonin
Chromatography
Temperature
Copolymers
Surface Properties
2006
66 Citations (Scopus)

Pharmacokinetics of fentanyl after single intravenous injection and constant rate infusion in dogs

Sano, T., Nishimura, R., Kanazawa, H., Igarashi, E., Itoh, Y., Mochizuki, M. & Sasaki, N., 2006 Jul, In : Veterinary Anaesthesia and Analgesia. 33, 4, p. 266-273 8 p.

Research output: Contribution to journalArticle

fentanyl
Fentanyl
intravenous injection
Intravenous Injections
pharmacokinetics
2004
4 Citations (Scopus)
Nitrogen Oxides
Atmospheric Pressure
Tocopherols
High performance liquid chromatography
Atmospheric pressure
2003
2 Citations (Scopus)

Effect of metabolic inhibition against CYP3A4 by catechins in bottled green tea drinks

Nakamura, T., Asada, E., Itoh, Y. & Kanazawa, H., 2003 Sep, In : Bunseki Kagaku. 52, 9, p. 769-773 5 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP3A
Catechin
Polyphenols
Antioxidants
Heat treatment
2002
25 Citations (Scopus)

Stereospecific analysis of loxoprofen in plasma by chiral column liquid chromatography with a circular dichroism-based detector

Kanazawa, H., Tsubayashi, A., Itoh, Y., Matsushima, Y., Mori, C., Kizu, J. & Higaki, M., 2002 Mar 1, In : Journal of Chromatography A. 948, 1-2, p. 303-308 6 p.

Research output: Contribution to journalArticle

Column chromatography
Liquid chromatography
Circular Dichroism
Liquid Chromatography
Detectors
2000
8 Citations (Scopus)

Copper(II)-catalyzed oxidation of d-α-tocopherol by oxygen in aqueous solution

Itoh, Y., Miyamoto, C., Matsushima, Y. & Matsumoto, S., 2000 Jan, In : Chemical and Pharmaceutical Bulletin. 48, 1, p. 71-76 6 p.

Research output: Contribution to journalArticle

Tocopherols
Copper
Metals
High Pressure Liquid Chromatography
Ions
19 Citations (Scopus)
Tocopherols
High performance liquid chromatography
Rats
High Pressure Liquid Chromatography
Tissue
3 Citations (Scopus)

Reaction of 2,2,5,7,8-pentamethyl-6-chromanol, an α-tocopherol analogue, with NO in the presence of oxygen

Itoh, Y., Nishio, T., Matsumoto, S., Kanazawa, H., Mochizuki, M. & Matsushima, Y., 2000 Dec 18, In : Bioorganic and Medicinal Chemistry Letters. 10, 24, p. 2709-2712 4 p.

Research output: Contribution to journalArticle

Tocopherols
Nitric Oxide
Oxygen
2,2,5,7,8-pentamethyl-1-hydroxychroman
1999
129 Citations (Scopus)

D-Aspartate stimulation of testosterone synthesis in rat Leydig cells

Itoh, Y., Homma, H., Lee, J. A. & Imai, K., 1999 Feb 12, In : FEBS Letters. 444, 2-3, p. 160-164 5 p.

Research output: Contribution to journalArticle

D-Aspartic Acid
Leydig Cells
Testosterone
Rats
Aspartic Acid
11 Citations (Scopus)

Effects of a water-soluble prodrug of vitamin E on doxorubicin-induced toxicity in mice

Itoh, Y., Takata, J., Yoshiharu Karube, A. & Matsushima, Y., 1999 Jul, In : Biological and Pharmaceutical Bulletin. 22, 7, p. 698-702 5 p.

Research output: Contribution to journalArticle

Prodrugs
Vitamin E
Doxorubicin
Tocopherols
Lipid Peroxidation
9 Citations (Scopus)

Oxidation of d-α-tocopherol in aqueous solution. Formation of colored products

Itoh, Y., Miyamoto, C., Matsushima, Y. & Matsumoto, S., 1999 Jul, In : Chemical and Pharmaceutical Bulletin. 47, 7, p. 923-927 5 p.

Research output: Contribution to journalArticle

Tocopherols
Oxidation
Deoxycholic Acid
Sodium Cholate
Cyclodextrins
1 Citation (Scopus)

Species absorbing in the 500-nm region in the reactions of pyridoxamine with pyrroloquinoline quinone and phenathrolinequinones

Itoh, Y., Matsushima, Y., Fujii, N., Fukuda, S., Kanazawa, H., Yoda, R. & Matsumoto, S., 1999 Dec, In : Chemical and Pharmaceutical Bulletin. 47, 12, p. 1774-1777 4 p.

Research output: Contribution to journalArticle

PQQ Cofactor
Pyridoxamine
Methanol
Pyridoxal Phosphate
Amines
75 Citations (Scopus)

Stimulation of steroidogenic acute regulatory protein (StAR) gene expression by D-aspartate in rat Leydig cells

Itoh, Y., Homma, H., Matsumoto, M. & Imai, K., 1999 Jul 9, In : FEBS Letters. 454, 3, p. 317-320 4 p.

Research output: Contribution to journalArticle

D-Aspartic Acid
Leydig Cells
Regulator Genes
Gene expression
Rats
3 Citations (Scopus)

Technetium-99m complexes with steroid-2-aminooxyethyliminodiacetic acid conjugates

Yoda, R., Karube, Y., Takata, J., Itoh, Y. & Matsushima, Y., 1999 Mar, In : Chemical and Pharmaceutical Bulletin. 47, 3, p. 413-416 4 p.

Research output: Contribution to journalArticle

Technetium
Tumors
Steroids
Progesterone
Androsterone
1998
1 Citation (Scopus)

Intermediate species absorbing in the 500-nm region in Al(III) catalyzed nonenzymatic transamination

Itoh, Y., Yoda, R. & Matsushima, Y., 1998, In : Chemical and Pharmaceutical Bulletin. 46, 12, p. 1849-1852 4 p.

Research output: Contribution to journalArticle

Pyridoxamine
Pyridoxal
Optical rotation
Ultraviolet detectors
Optical Rotation
1997
12 Citations (Scopus)

Water-soluble prodrug of vitamin E for parenteral use and its effect on endotoxin-induced liver toxicity

Takata, J., Ito, S., Karube, Y., Itoh, Y. & Matsushima, Y., 1997 Feb, In : Biological and Pharmaceutical Bulletin. 20, 2, p. 204-209 6 p.

Research output: Contribution to journalArticle

Tocopherols
Prodrugs
Vitamin E
Endotoxins
Water
1995
26 Citations (Scopus)

Determination of medetomidine, atipamezole and midazolam in pig plasma by liquid chromatography-mass spectrometry

Kanazawa, H., Nishimura, R., Sasaki, N., Takeuchi, A., Takai, N., Itoh, Y. & Matsushima, Y., 1995, In : Biomedical Chromatography. 9, 4, p. 188-191 4 p.

Research output: Contribution to journalArticle

Medetomidine
Atmospheric Pressure
Pharmacokinetics
Midazolam
Liquid chromatography
28 Citations (Scopus)

Prodrugs of vitamin E. 1. Preparation and enzymatic hydrolysis of aminoalkanecarboxylic acid esters of d‐α‐tocopherol

Takata, J., Karube, Y., Itoh, Y. & Matsushima, Y., 1995, In : Journal of Pharmaceutical Sciences. 84, 1, p. 96-100 5 p.

Research output: Contribution to journalArticle

Prodrugs
Vitamin E
Esters
Hydrolysis
Acids
1994
29 Citations (Scopus)

High-performance liquid chromatographic determination of catecholamine metabolites and 5-hydroxyindoleacetic acid in human urine using a mixed-mode column and an eight-channel electrode electrochemical detector

Mashige, F., Ohkubo, A., Matsushima, Y., Takano, M., Tsuchiya, E., Kanazawa, H., Itoh, Y., Takai, N., Shinozuka, N. & Sakuma, I., 1994 Aug 5, In : Journal of Chromatography B: Biomedical Sciences and Applications. 658, 1, p. 63-68 6 p.

Research output: Contribution to journalArticle

Electrochemical electrodes
Vanilmandelic Acid
Hydroxyindoleacetic Acid
Vanillic Acid
Metabolites
1 Citation (Scopus)

Simultaneous determination of catecholamines, serotonin, and their precursors and metabolites in body fluid by an HPLC system with multi-electrode electrochemical detector

Mashige, F., Takai, N., Matsushima, Y., Ito, A., Takano, M., Tsuchiya, E., Kanazawa, H., Itoh, Y., Shinozuka, N. & Wada, H., 1994 Jun, In : Rinsho byori. The Japanese journal of clinical pathology. 42, 6, p. 591-599 9 p.

Research output: Contribution to journalArticle

Hydroxyindoleacetic Acid
Body Fluids
Catecholamines
Cerebrospinal Fluid
3,4-Dihydroxyphenylacetic Acid
1993
16 Citations (Scopus)

Comparison of columns of chemically modified porous glass and silica in reversed-phase high-performance liquid chromatography of ginsenosides

Kanazawa, H., Itoh, Y., Kurosaki, E., Matsushima, Y. & Takai, N., 1993 Feb 19, In : Journal of Chromatography A. 632, 1-2, p. 79-85 7 p.

Research output: Contribution to journalArticle

Ginsenosides
High performance liquid chromatography
Reverse-Phase Chromatography
Silicon Dioxide
Pore size
20 Citations (Scopus)

Determination of acidic saponins in crude drugs by high- performance liquid chromatography on octadecylsilyl porous glass

Kanazawa, H., Itoh, Y., Matsushima, Y., Tomoda, M. & Takai, N., 1993 Feb 5, In : Journal of Chromatography A. 630, 1-2, p. 408-414 7 p.

Research output: Contribution to journalArticle

Saponins
High performance liquid chromatography
Glass
High Pressure Liquid Chromatography
Bupleurum
1 Citation (Scopus)

Isolation and identification of canine plasma components suspected as uremic toxins.

Kawamura, M., Ohashi, F., Nagata, Y., Takai, N., Motoie, H., Nishimura, R., Itoh, Y. & Takeuchi, A., 1993 Apr, In : The Journal of veterinary medical science / the Japanese Society of Veterinary Science. 55, 2, p. 265-270 6 p.

Research output: Contribution to journalArticle

Canidae
toxins
high performance liquid chromatography
High Pressure Liquid Chromatography
hippuric acid
26 Citations (Scopus)

Liquid chromatography-mass spectrometry for the determination of medetomidine and other anaesthetics in plasma

Kanazawa, H., Itoh, Y., Matsushima, Y., Takai, N., Uchiyama, H., Nishimura, R. & Takeuchi, A., 1993 Feb 12, In : Journal of Chromatography A. 631, 1-2, p. 215-220 6 p.

Research output: Contribution to journalArticle

Medetomidine
Liquid chromatography
Liquid Chromatography
Mass spectrometry
Anesthetics
4 Citations (Scopus)

Solvolysis of pyridoxal hydrochloride in alcohols

Itoh, Y., Yoda, R. & Matsushima, Y., 1993, In : Chemical and Pharmaceutical Bulletin. 41, 6, p. 1019-1022 4 p.

Research output: Contribution to journalArticle

Pyridoxal
Alcohols
Kinetics
Schiff Bases
Phenol
1991

High-performance liquid chromatography of saponins of crude drugs on chemically modified porous glass

Kanazawa, H., Itoh, Y., Matsushima, Y., Tomada, M. & Takai, N., 1991, In : Journal of Pharmacobio-Dynamics. 14, 4

Research output: Contribution to journalArticle

Saponins
Glass
High Pressure Liquid Chromatography
Pharmaceutical Preparations

Intermediate species absorbing in the 500-nm region in metal ion mediated pyridoxal catalysis

Matsushima, Y., Itoh, Y. & Kojima, M., 1991, In : Journal of Pharmacobio-Dynamics. 14, 11

Research output: Contribution to journalArticle

Pyridoxal
Catalysis
Metals
Ions
5 Citations (Scopus)

Preparative high-performance liquid chromatography on chemically modified porous glass. Isolation of acidic saponins from ginseng

Kanazawa, H., Itoh, Y., Matsushima, Y., Tomoda, M. & Takai, N., 1991, In : Journal of Chromatography A. 537, C, p. 469-474 6 p.

Research output: Contribution to journalArticle

pH
High pressure liquid chromatography
Saponins
High performance liquid chromatography
Glass

Studies on catecholamine by HPLC with multi ECD

Takai, N., Shinozuka, N., Mashige, F., Ohkubo, A., Nukina, N., Iijima, S., Fukui, Y., Sakuma, I., Itou, F., Matsushima, Y. & Itoh, Y., 1991, In : Analytical Sciences. 7, p. 955-956 2 p.

Research output: Contribution to journalArticle

Catecholamines
Detectors
Cerebrospinal fluid
Electrodes
Fluids
1990
7 Citations (Scopus)

Preparative high-performance liquid chromatography on chemically modified porous glass. Isolation of saponins from ginseng

Kanazawa, H., Itoh, Y., Matsushima, Y., Tomoda, M. & Takai, N., 1990, In : Chemical and Pharmaceutical Bulletin. 38, 6, p. 1630-1632 3 p.

Research output: Contribution to journalArticle

Ginsenosides
Panax
Saponins
Medicinal Plants
Glass
29 Citations (Scopus)

Simultaneous determination of ginsenosides and saikosaponins by high-performance liquid chromatography

Kanazawa, H., Itoh, Y., Matsushima, Y., Tomoda, M. & Takai, N., 1990 May 16, In : Journal of Chromatography A. 507, C, p. 327-332 6 p.

Research output: Contribution to journalArticle

Ginsenosides
Saponins
High performance liquid chromatography
Bupleurum
High Pressure Liquid Chromatography
1989
2 Citations (Scopus)

A chemical model of catechol-O-methyltransferase. Methylation of 3,4-dihydroxybenzaldehyde in aqueous solution

Sugata, S., Ishihara, S., Watanabe, Y., Itoh, Y. & Matsushima, Y., 1989, In : Chemical and Pharmaceutical Bulletin. 37, 5, p. 1143-1146 4 p.

Research output: Contribution to journalArticle

Benzaldehydes
Catechols
Chemical Models
Catechol O-Methyltransferase
Methylation
8 Citations (Scopus)

High-performance liquid chromatographic analysis of ginsenosides in pharmaceutical preparations

Kanazawa, H., Itoh, Y., Matsushima, Y., Tomoda, M. & Takai, N., 1989, In : Japanese Journal of Pharmacognosy. 43, 2, p. 121-128 8 p.

Research output: Contribution to journalArticle

Ginsenosides
High Pressure Liquid Chromatography
Pharmaceutical Preparations
1987

Analysis of ultraviolet-absorbing compounds in human urine by high performance liquid chromatography

Itoh, Y., Yokoyama, Y., Nagura, S., Sugata, S., Fujie, T., Matsushima, Y. & Takai, N., 1987, In : Journal of Liquid Chromatography. 10, 13, p. 2993-2998 6 p.

Research output: Contribution to journalArticle

High performance liquid chromatography
High Pressure Liquid Chromatography
Urine
Anion Exchange Resins
Individuality
1 Citation (Scopus)

Chromatographic separation and identification of human urine components

Itoh, Y., Matsushima, Y., Ugai, H., Kikuchi, M. & Takai, N., 1987 Dec, In : Chromatographia. 24, 1, p. 317-318 2 p.

Research output: Contribution to journalArticle

Anion Exchange Resins
Forensic Anthropology
Stainless Steel
Uric Acid
Buffers
11 Citations (Scopus)

High-performance liquid chromatographic analysis of ginsenosides in Panax ginseng extracts using glass-ODS column

Kanazawa, H., Itoh, Y., Matsushima, Y., Tomoda, M. & Takai, N., 1987 Dec, In : Chromatographia. 24, 1, p. 517-519 3 p.

Research output: Contribution to journalArticle

Ginsenosides
Panax
ginsenoside Rg2
High performance liquid chromatography
Glass
1 Citation (Scopus)

Mult-component analysis of urine of dogs with liver diseases by high-performance liquid chromatography

Abe, Y., Kobayashi, E., Suzuki, N., Kaneko, A., Fujie, T., Itoh, Y., Matsushima, Y., Takai, N., Watanabe, T. & Otsubo, O., 1987, In : Journal of Chromatography A. 386, C, p. 11-17 7 p.

Research output: Contribution to journalArticle

High performance liquid chromatography
Liver
Liver Diseases
High Pressure Liquid Chromatography
Liver Failure
2 Citations (Scopus)

N-Pyridoxylidenehydrazine-N’, N’-diacetic Acid. III.1) Formation of Metal Chelates in Solution

Matsushima, Y., Itoh, Y., Tamano, Y., Sugata, S., Fujie, T., Karube, Y. & Kono, A., 1987, In : Chemical and Pharmaceutical Bulletin. 35, 12, p. 4695-4699 5 p.

Research output: Contribution to journalArticle

hydrazine
Metals
Acids
Methanol
Hydrazines
1985
6 Citations (Scopus)

Analysis of antipyretics by semimicro liquid chromatography

Matsushima, Y., Itoh, Y., Niyomura, M., Takakusagi, K. & Takai, N., 1985 Sep 20, In : Journal of Chromatography A. 332, C, p. 269-273 5 p.

Research output: Contribution to journalArticle

Antipyretics
divinyl benzene
Liquid chromatography
Liquid Chromatography
Glyceryl Ethers
12 Citations (Scopus)

High-performance liquid chromatography of anti-pyretics on chemically modified porous glass

Matsushima, Y., Itoh, Y., Takakusagi, K., Niyomura, M. & Takai, N., 1985 Sep 20, In : Journal of Chromatography A. 332, C, p. 265-268 4 p.

Research output: Contribution to journalArticle

High performance liquid chromatography
Glass
Fever
High Pressure Liquid Chromatography
Glyceryl Ethers