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Research Output 2004 2019

  • 1470 Citations
  • 22 h-Index
  • 52 Article
  • 1 Comment/debate
  • 1 Letter
2019

Corrigendum to “TFOS DEWS II pathophysiology report” (The Ocular Surface (2017) 15(3) (438–510), (S1542012417301349), (10.1016/j.jtos.2017.05.011))

Bron, A. J., de Paiva, C. S., Chauhan, S. K., Bonini, S., Gabison, E. E., Jain, S., Knop, E., Markoulli, M., Ogawa, Y., Perez, V., Uchino, Y., Yokoi, N., Zoukhri, D. & Sullivan, D. A., 2019 Oct, In : Ocular Surface. 17, 4, 1 p.

Research output: Contribution to journalComment/debate

corrigendum
2018
1 Citation (Scopus)

A novel and innovative paper-based analytical device for assessing tear lactoferrin of dry eye patients

Sonobe, H., Ogawa, Y., Yamada, K., Shimizu, E., Uchino, Y., Kamoi, M., Saijo, Y., Yamane, M., Citterio, D., Suzuki, K. & Tsubota, K., 2018 Jan 1, (Accepted/In press) In : Ocular Surface.

Research output: Contribution to journalArticle

Lactoferrin
Tears
Eye Diseases
Equipment and Supplies
Enzyme-Linked Immunosorbent Assay
1 Citation (Scopus)

Association between tear film break up time and blink interval in visual display terminal users

Uchino, M., Kawashima, M., Uchino, Y., Tsubota, K. & Yokoi, N., 2018 Jan 1, In : International Journal of Ophthalmology. 11, 10, p. 1691-1697 7 p.

Research output: Contribution to journalArticle

Tears
Blinking
Visual Acuity
Logistic Models
Odds Ratio
3 Citations (Scopus)

Galectin-3 is an amplifier of the interleukin-1β-mediated inflammatory response in corneal keratinocytes

Uchino, Y., Woodward, A. M., Mauris, J., Peterson, K., Verma, P., Nilsson, U. J., Rajaiya, J. & Argüeso, P., 2018 Jan 1, (Accepted/In press) In : Immunology.

Research output: Contribution to journalArticle

Galectin 3
Interleukin-1
Keratinocytes
Interleukin-8
Interleukin-6
1 Citation (Scopus)

Prognosis after lamellar keratoplasty for limbal dermoids using preserved corneas

Yamashita, K., Hatou, S., Uchino, Y., Tsubota, K. & Shimmura, S., 2018 Jan 1, (Accepted/In press) In : Japanese Journal of Ophthalmology.

Research output: Contribution to journalArticle

Dermoid Cyst
Corneal Transplantation
Cornea
Amblyopia
Visual Acuity
1 Citation (Scopus)

The evaluation of dry eye mobile apps for screening of dry eye disease and educational tear event in Japan

Uchino, M., Kawashima, M., Uchino, Y., Suzuki, N., Mitamura, H., Mizuno, M., Hori, Y., Yokoi, N. & Tsubota, K., 2018 Jan 1, (Accepted/In press) In : Ocular Surface.

Research output: Contribution to journalArticle

Mobile Applications
Eye Diseases
Tears
Japan
Visual Acuity
2 Citations (Scopus)

The Ocular Surface Glycocalyx and its Alteration in Dry Eye Disease: A Review

Uchino, Y., 2018 Nov 1, In : Investigative ophthalmology & visual science. 59, 14, p. DES157-DES162

Research output: Contribution to journalArticle

Wettability
Glycocalyx
Eye Diseases
Mucins
Galectin 3
1 Citation (Scopus)

What Have We Learned From the Osaka Study?

Uchino, M., Uchino, Y., Kawashima, M., Yokoi, N. & Tsubota, K., 2018 Nov 1, In : Cornea. 37, p. S62-S66

Research output: Contribution to journalArticle

Eye Diseases
Happiness
Sleep
Exercise
Fluorescein
2017

Evaluation of a paper-based visual acuity questionnaire

Uchino, M., Kawashima, M., Kaido, M., Suwaki, K., Uchino, Y., Kawachi, I., Negishi, K. & Tsubota, K., 2017 Jun 27, In : Clinical Ophthalmology. 11, p. 1213-1217 5 p.

Research output: Contribution to journalArticle

Visual Acuity
Surveys and Questionnaires
Cross-Sectional Studies
197 Citations (Scopus)

TFOS DEWS II pathophysiology report

Bron, A. J., de Paiva, C. S., Chauhan, S. K., Bonini, S., Gabison, E. E., Jain, S., Knop, E., Markoulli, M., Ogawa, Y., Perez, V., Uchino, Y., Yokoi, N., Zoukhri, D. & Sullivan, D. A., 2017, (Accepted/In press) In : Ocular Surface.

Research output: Contribution to journalArticle

Tears
Eye Diseases
Keratitis
Dry Eye Syndromes
Meibomian Glands
2016
7 Citations (Scopus)

Differential effect of rebamipide on transmembrane mucin biosynthesis in stratified ocular surface epithelial cells

Uchino, Y., Woodward, A. M. & Argüeso, P., 2016 Dec 1, In : Experimental Eye Research. 153, p. 1-7 7 p.

Research output: Contribution to journalArticle

Mucins
Epithelial Cells
Glycocalyx
Eye Diseases
Protein Biosynthesis
8 Citations (Scopus)

Impact of Cigarette Smoking on Tear Function and Correlation between Conjunctival Goblet Cells and Tear MUC5AC Concentration in Office Workers

Uchino, Y., Uchino, M., Yokoi, N., Dogru, M., Kawashima, M., Komuro, A., Sonomura, Y., Kato, H., Argüeso, P., Kinoshita, S. & Tsubota, K., 2016 Jun 14, In : Scientific Reports. 6, 27699.

Research output: Contribution to journalArticle

Goblet Cells
Tears
Smoking
Cell Count
Periodic Acid
18 Citations (Scopus)

The association of sleep quality with dry eye disease: The Osaka study

Kawashima, M., Uchino, M., Yokoi, N., Uchino, Y., Dogru, M., Komuro, A., Sonomura, Y., Kato, H., Kinoshita, S. & Tsubota, K., 2016 Jun 1, In : Clinical Ophthalmology. 10, p. 1015-1021 7 p.

Research output: Contribution to journalArticle

Eye Diseases
Sleep
Fluorescein
Tears
Japan
2015
23 Citations (Scopus)

Alteration of galectin-3 in tears of patients with dry eye disease

Uchino, Y., Mauris, J., Woodward, A. M., Dieckow, J., Amparo, F., Dana, R., Mantelli, F. & Argüeso, P., 2015 Jun 1, In : American Journal of Ophthalmology. 159, 6, p. 1027-1035.e3

Research output: Contribution to journalArticle

Galectin 3
Eye Diseases
Tears
Matrix Metalloproteinase 9
Healthy Volunteers
41 Citations (Scopus)

Associations between subjective happiness and dry eye disease: A new perspective from the Osaka study

Kawashima, M., Uchino, M., Yokoi, N., Uchino, Y., Dogru, M., Komuro, A., Sonomura, Y., Kato, H., Kinoshita, S., Mimura, M. & Tsubota, K., 2015 Apr 1, In : PLoS One. 10, 4, e0123299.

Research output: Contribution to journalArticle

eye diseases
Happiness
Eye Diseases
signs and symptoms (animals and humans)
eyes
2 Citations (Scopus)

Correction: Oxidative stress induced inflammation initiates functional decline of tear production

Uchino, Y., Kawakita, T., Miyazawa, M., Ishii, T., Onouchi, H., Yasuda, K., Ogawa, Y., Shimmura, S., Ishii, N. & Tsubota, K., 2015 May 11, In : PLoS One. 10, 5, e0127720.

Research output: Contribution to journalArticle

Oxidative stress
9 Citations (Scopus)

Galectin-3 as a regulator of the epithelial junction: Implications to wound repair and cancer

Argüeso, P., Mauris, J. & Uchino, Y., 2015 Jul 3, In : Tissue Barriers. 3, 3, p. 1-6 6 p.

Research output: Contribution to journalArticle

Galectin 3
Adhesives
Repair
Tissue
Cell signaling
51 Citations (Scopus)

Importance of tear film instability in dry eye disease in office workers using visual display terminals: The osaka study

Yokoi, N., Uchino, M., Uchino, Y., Dogru, M., Kawashima, M., Komuro, A., Sonomura, Y., Kato, H., Tsubota, K. & Kinoshita, S., 2015 Apr 1, In : American Journal of Ophthalmology. 159, 4, p. 748-754 7 p.

Research output: Contribution to journalArticle

Eye Diseases
Tears
Signs and Symptoms
Fluorescein
2014
31 Citations (Scopus)

Alteration of tear mucin 5AC in office workers using visual display terminals: The Osaka study

Uchino, Y., Uchino, M., Yokoi, N., Dogru, M., Kawashima, M., Okada, N., Inaba, T., Tamaki, S., Komuro, A., Sonomura, Y., Kato, H., Argüeso, P., Kinoshita, S. & Tsubota, K., 2014, In : JAMA Ophthalmology. 132, 8, p. 985-992 8 p.

Research output: Contribution to journalArticle

Mucin 5AC
Eye Diseases
Tears
17 Citations (Scopus)

Decreased tear volume in patients with metabolic syndrome: The Osaka study

Kawashima, M., Uchino, M., Yokoi, N., Dogru, M., Uchino, Y., Komuro, A., Sonomura, Y., Kato, H., Kinoshita, S. & Tsubota, K., 2014 Mar, In : British Journal of Ophthalmology. 98, 3, p. 418-420 3 p.

Research output: Contribution to journalArticle

Metabolic Syndrome X
Dry Eye Syndromes
Lacrimal Apparatus Diseases
Tears
Cross-Sectional Studies
75 Citations (Scopus)

Dry eye disease and work productivity loss in visual display users: The Osaka study

Uchino, M., Uchino, Y., Dogru, M., Kawashima, M., Yokoi, N., Komuro, A., Sonomura, Y., Kato, H., Kinoshita, S., Schaumberg, D. A. & Tsubota, K., 2014 Feb, In : American Journal of Ophthalmology. 157, 2, p. 294-300 7 p.

Research output: Contribution to journalArticle

Eye Diseases
Efficiency
Time Management
Intelligence Tests
Salaries and Fringe Benefits
23 Citations (Scopus)

Dry-eye screening by using a functional visual acuity measurement system: The Osaka study

Kaido, M., Uchino, M., Yokoi, N., Uchino, Y., Dogru, M., Kawashima, M., Komuro, A., Sonomura, Y., Kato, H., Kinoshita, S. & Tsubota, K., 2014 May 6, In : Investigative Ophthalmology and Visual Science. 55, 5, p. 3275-3281 7 p.

Research output: Contribution to journalArticle

Visual Acuity
Tears
Sensitivity and Specificity
Discriminant Analysis
Blinking
16 Citations (Scopus)

The association between dry eye disease and physical activity as well as sedentary behavior: Results from the Osaka study

Kawashima, M., Uchino, M., Yokoi, N., Uchino, Y., Dogru, M., Komuro, A., Sonomura, Y., Kato, H., Nishiwaki, Y., Kinoshita, S. & Tsubota, K., 2014, In : Journal of Ophthalmology. 2014, 943786.

Research output: Contribution to journalArticle

Eye Diseases
Metabolic Equivalent
Tears
Longitudinal Studies
Cross-Sectional Studies
2013
Ophthalmic Solutions
Hyaluronic Acid
Tears
Patient Satisfaction
Therapeutics
127 Citations (Scopus)

Prevalence of dry eye disease and its risk factors in visual display terminal users: The Osaka study

Uchino, M., Yokoi, N., Uchino, Y., Dogru, M., Kawashima, M., Komuro, A., Sonomura, Y., Kato, H., Kinoshita, S., Schaumberg, D. A. & Tsubota, K., 2013 Oct, In : American Journal of Ophthalmology. 156, 4

Research output: Contribution to journalArticle

Eye Diseases
Tears
Odds Ratio
Confidence Intervals
Public Health
5 Citations (Scopus)

The impact of tear functions on visual outcome following keratoplasty in eyes with keratoconus

Hara, S., Kojima, T., Dogru, M., Uchino, Y., Goto, E., Matsumoto, Y., Kawakita, T., Tsubota, K. & Shimazaki, J., 2013 Jul, In : Graefe's Archive for Clinical and Experimental Ophthalmology. 251, 7, p. 1763-1770 8 p.

Research output: Contribution to journalArticle

Keratoconus
Corneal Transplantation
Tears
Visual Acuity
Corneal Topography
2012
2 Citations (Scopus)

[A quality of life questionnaire for Japanese allergic conjunctival disease].

Fukagawa, K., Fujishima, H., Fukushima, A., Sumi, T., Okamoto, S., Shoji, J., Satake, Y., Ohno, S., Namba, K., Kitaichi, N., Ebihara, N., Takahashi, H., Kumagai, N., Uchino, Y., Uchino, M., Murayama, K., Sakata, M., Uchio, E., Takamura, E., Ohashi, Y. & 2 others, Ohkubo, K. & Satoh, T., 2012 May, In : Nippon Ganka Gakkai zasshi. 116, 5, p. 494-502 9 p.

Research output: Contribution to journalArticle

Conjunctival Diseases
Quality of Life
Pruritus
Statistical Factor Analysis
Surveys and Questionnaires
36 Citations (Scopus)

A new mouse model of dry eye disease: Oxidative stress affects functional decline in the Lacrimal Gland

Uchino, Y., Kawakita, T., Ishii, T., Ishii, N. & Tsubota, K., 2012 Nov, In : Cornea. 31, 11 SUPPL.1

Research output: Contribution to journalArticle

Lacrimal Apparatus
Eye Diseases
Oxidative Stress
Tears
Mitochondria
34 Citations (Scopus)

Changes in dry eye diagnostic status following implementation of revised Japanese dry eye diagnostic criteria

Uchino, Y., Uchino, M., Dogru, M., Ward, S., Yokoi, N. & Tsubota, K., 2012 Jan, In : Japanese Journal of Ophthalmology. 56, 1, p. 8-13 6 p.

Research output: Contribution to journalArticle

Eye Diseases
Rose Bengal
Fluorescein
Tears
Japan
26 Citations (Scopus)
Hematopoietic Stem Cell Transplantation
Peripheral Blood Stem Cell Transplantation
Stem Cells
Fetal Blood
Bone Marrow Transplantation
5 Citations (Scopus)

Improvement of accommodation with anti-oxidant supplementation in visual display terminal users

Uchino, Y., Uchino, M., Dogru, M., Fukagawa, K. & Tsubota, K., 2012, In : Journal of Nutrition, Health and Aging. 16, 5, p. 478-481 4 p.

Research output: Contribution to journalArticle

Oxidants
Antioxidants
Placebos
Clinical Trials
11 Citations (Scopus)

Mitochondrial superoxide anion overproduction in Tet-mev-1 transgenic mice accelerates age-dependent corneal cell dysfunctions

Onouchi, H., Ishii, T., Miyazawa, M., Uchino, Y., Yasuda, K., Hartman, P. S., Kawai, K., Tsubota, K. & Ishii, N., 2012 Aug, In : Investigative Ophthalmology and Visual Science. 53, 9, p. 5780-5787 8 p.

Research output: Contribution to journalArticle

Tetracycline
Superoxides
Transgenic Mice
Oxidative Stress
Corneal Endothelium
56 Citations (Scopus)

Oxidative Stress Induced Inflammation Initiates Functional Decline of Tear Production

Uchino, Y., Kawakita, T., Miyazawa, M., Ishii, T., Onouchi, H., Yasuda, K., Ogawa, Y., Shimmura, S., Ishii, N. & Tsubota, K., 2012 Oct 5, In : PLoS One. 7, 10, e45805.

Research output: Contribution to journalArticle

lacrimal apparatus
succinate dehydrogenase (quinone)
Oxidative stress
Tears
Lacrimal Apparatus
23 Citations (Scopus)

The antiaging approach for the treatment of dry eye

Tsubota, K., Kawashima, M., Inaba, T., Dogru, M., Matsumoto, Y., Ishida, R., Kaido, M., Kojima, T., Uchino, M., Uchino, Y., Ogawa, Y., Nakamura, S., Higuchi, A., Shinmura, K., Watanabe, M. & Kawakita, T., 2012 Nov, In : Cornea. 31, 11 SUPPL.1

Research output: Contribution to journalArticle

Free Radicals
Therapeutics
Ophthalmic Solutions
Tears
Patient Satisfaction
2011

[Risk factors of severe peripheral corneal ulcers].

Suzuki, A., Matsumoto, Y., Uchino, Y., Kawakita, T., Shimmura, S. & Tsubota, K., 2011 Feb, In : Nippon Ganka Gakkai zasshi. 115, 2, p. 116-121 6 p.

Research output: Contribution to journalArticle

Corneal Ulcer
Ulcer
Immunosuppressive Agents
Rheumatoid Arthritis
Therapeutics
25 Citations (Scopus)

Comparison of corneal thickness and haze in DSAEK and penetrating keratoplasty

Uchino, Y., Shimmura, S., Yamaguchi, T., Kawakita, T., Matsumoto, Y., Negishi, K. & Tsubota, K., 2011 Mar, In : Cornea. 30, 3, p. 287-290 4 p.

Research output: Contribution to journalArticle

Descemet Stripping Endothelial Keratoplasty
Penetrating Keratoplasty
Cornea
Corneal Transplantation
Germany
2010
33 Citations (Scopus)

Comparison of anterior and posterior corneal surface irregularity in descemet stripping automated endothelial keratoplasty and penetrating keratoplasty

Yamaguchi, T., Negishi, K., Yamaguchi, K., Dogru, M., Uchino, Y., Shimmura, S. & Tsubota, K., 2010 Oct, In : Cornea. 29, 10, p. 1086-1090 5 p.

Research output: Contribution to journalArticle

Descemet Stripping Endothelial Keratoplasty
Penetrating Keratoplasty
Astigmatism
Cornea
2009
1 Citation (Scopus)
Benign Mucous Membrane Pemphigoid
Intravenous Immunoglobulins
Transplantation
Immunosuppression
Autoimmune Diseases
2 Citations (Scopus)

Dry eye disease in Japan: An epidemiologic study

Uchino, M., Uchino, Y., Dogru, M., Schaumberg, D. A. & Tsubota, K., 2009, In : Cornea. 28, SUPPL. 1

Research output: Contribution to journalArticle

Eye Diseases
Epidemiologic Studies
Japan
Contact Lenses
Students
51 Citations (Scopus)

Effect of anterior and posterior corneal surface irregularity on vision after Descemet-stripping endothelial keratoplasty

Yamaguchi, T., Negishi, K., Yamaguchi, K., Murat, D., Uchino, Y., Shimmura, S. & Tsubota, K., 2009 Apr, In : Journal of Cataract and Refractive Surgery. 35, 4, p. 688-694 7 p.

Research output: Contribution to journalArticle

Descemet Stripping Endothelial Keratoplasty
Visual Acuity
Tokyo
Ophthalmology
Cornea
10 Citations (Scopus)

Late irreversible corneal oedema after laser iridotomy

Shimazaki, J., Uchino, Y. & Tsubota, K., 2009 Jan, In : British Journal of Ophthalmology. 93, 1, p. 125-126 2 p.

Research output: Contribution to journalArticle

Corneal Edema
Angle Closure Glaucoma
Retinal Diseases
Laser Therapy
Iris
2008
55 Citations (Scopus)

Japan Ministry of Health Study on Prevalence of Dry Eye Disease Among Japanese High School Students

Uchino, M., Dogru, M., Uchino, Y., Fukagawa, K., Shimmura, S., Takebayashi, T., Schaumberg, D. A. & Tsubota, K., 2008 Dec, In : American Journal of Ophthalmology. 146, 6

Research output: Contribution to journalArticle

Eye Diseases
Contact Lenses
Japan
Cross-Sectional Studies
Students
8 Citations (Scopus)

Management of evaporative dry eye in ectrodactyly-ectodermal dysplasia-clefting syndrome

Ota, Y., Matsumoto, Y., Dogru, M., Goto, E., Uchino, Y., Endo, K. & Tsubota, K., 2008 Sep, In : Optometry and Vision Science. 85, 9

Research output: Contribution to journalArticle

Eye Diseases
Ointment Bases
Lipids
Meibomian Glands
Corneal Diseases
170 Citations (Scopus)

Prevalence of Dry Eye Disease among Japanese Visual Display Terminal Users

Uchino, M., Schaumberg, D. A., Dogru, M., Uchino, Y., Fukagawa, K., Shimmura, S., Satoh, T., Takebayashi, T. & Tsubota, K., 2008 Nov, In : Ophthalmology. 115, 11, p. 1982-1988 7 p.

Research output: Contribution to journalArticle

Eye Diseases
Contact Lenses
Odds Ratio
Outcome Assessment (Health Care)
Confidence Intervals
2007
31 Citations (Scopus)
Scaffolds
Polymers
Alcohols
Membranes
Collagen
3 Citations (Scopus)

Combination treatment of intravenous immunoglobulin and cultivated oral mucosal epithelial transplantation for ocular cicatricial pemphigoid [2]

Uchino, Y., Takahashi, S., Uchino, M. & Shimazaki, J., 2007 Jan, In : British Journal of Ophthalmology. 91, 1, p. 117-118 2 p.

Research output: Contribution to journalLetter

Benign Mucous Membrane Pemphigoid
Combined Modality Therapy
Bullous Pemphigoid
Eye Diseases
Intravenous Immunoglobulins
39 Citations (Scopus)

The application of in vivo confocal scanning laser microscopy in the management of Acanthamoeba keratitis

Matsumoto, Y., Dogru, M., Sato, E. A., Katono, Y., Uchino, Y., Shimmura, S. & Tsubota, K., 2007 Jul 25, In : Molecular Vision. 13, p. 1319-1326 8 p.

Research output: Contribution to journalArticle

Acanthamoeba Keratitis
Confocal Microscopy
Cornea
Retina
Contact Lens Solutions
2006
61 Citations (Scopus)

Collagen-immobilized poly(vinyl alcohol) as an artificial cornea scaffold that supports a stratified corneal epithelium

Miyashita, H., Shimmura, S., Kobayashi, H., Taguchi, T., Asano-Kato, N., Uchino, Y., Kato, M., Shimazaki, J., Tanaka, J. & Tsubota, K., 2006 Jan, In : Journal of Biomedical Materials Research - Part B Applied Biomaterials. 76, 1, p. 56-63 8 p.

Research output: Contribution to journalArticle

Collagen
Scaffolds
Alcohols
Keratin-3
Tissue
20 Citations (Scopus)

Long-standing Bullous Keratopathy Is Associated with Peripheral Conjunctivalization and Limbal Deficiency

Uchino, Y., Goto, E., Takano, Y., Dogru, M., Shinozaki, N., Shimmura, S., Yagi, Y., Tsubota, K. & Shimazaki, J., 2006 Jul, In : Ophthalmology. 113, 7, p. 1098-1101 4 p.

Research output: Contribution to journalArticle

Goblet Cells
Penetrating Keratoplasty
Cornea
Cell Biology
Stem Cells

Microkeratome assisted deep lamellar keratoprosthesis

Shimmura, S., Miyashita, H., Uchino, Y., Taguchi, T., Kobayashi, H., Shimazaki, J., Tanaka, J. & Tsubota, K., 2006 Jul, In : British Journal of Ophthalmology. 90, 7, p. 826-829 4 p.

Research output: Contribution to journalArticle

Descemet Membrane
Vimentin
Cornea
Poly I
Staining and Labeling