• 1512 Citations
  • 22 h-Index
20042019

Research output per year

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Research Output

  • 1512 Citations
  • 22 h-Index
  • 49 Article
  • 3 Letter
  • 2 Comment/debate
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Article
2018

A novel and innovative paper-based analytical device for assessing tear lactoferrin of dry eye patients

Sonobe, H., Ogawa, Y., Yamada, K., Shimizu, E., Uchino, Y., Kamoi, M., Saijo, Y., Yamane, M., Citterio, D., Suzuki, K. & Tsubota, K., 2018 Jan 1, (Accepted/In press) In : Ocular Surface.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Association between tear film break up time and blink interval in visual display terminal users

Uchino, M., Kawashima, M., Uchino, Y., Tsubota, K. & Yokoi, N., 2018 Jan 1, In : International Journal of Ophthalmology. 11, 10, p. 1691-1697 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Galectin-3 is an amplifier of the interleukin-1β-mediated inflammatory response in corneal keratinocytes

Uchino, Y., Woodward, A. M., Mauris, J., Peterson, K., Verma, P., Nilsson, U. J., Rajaiya, J. & Argüeso, P., 2018 Jan 1, (Accepted/In press) In : Immunology.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Prognosis after lamellar keratoplasty for limbal dermoids using preserved corneas

Yamashita, K., Hatou, S., Uchino, Y., Tsubota, K. & Shimmura, S., 2018 Jan 1, (Accepted/In press) In : Japanese Journal of Ophthalmology.

Research output: Contribution to journalArticle

1 Citation (Scopus)

The evaluation of dry eye mobile apps for screening of dry eye disease and educational tear event in Japan

Uchino, M., Kawashima, M., Uchino, Y., Suzuki, N., Mitamura, H., Mizuno, M., Hori, Y., Yokoi, N. & Tsubota, K., 2018 Jan 1, (Accepted/In press) In : Ocular Surface.

Research output: Contribution to journalArticle

1 Citation (Scopus)

The Ocular Surface Glycocalyx and its Alteration in Dry Eye Disease: A Review

Uchino, Y., 2018 Nov 1, In : Investigative ophthalmology & visual science. 59, 14, p. DES157-DES162

Research output: Contribution to journalArticle

2 Citations (Scopus)

What Have We Learned From the Osaka Study?

Uchino, M., Uchino, Y., Kawashima, M., Yokoi, N. & Tsubota, K., 2018 Nov 1, In : Cornea. 37, p. S62-S66

Research output: Contribution to journalArticle

1 Citation (Scopus)
2017

Evaluation of a paper-based visual acuity questionnaire

Uchino, M., Kawashima, M., Kaido, M., Suwaki, K., Uchino, Y., Kawachi, I., Negishi, K. & Tsubota, K., 2017 Jun 27, In : Clinical Ophthalmology. 11, p. 1213-1217 5 p.

Research output: Contribution to journalArticle

TFOS DEWS II pathophysiology report

Bron, A. J., de Paiva, C. S., Chauhan, S. K., Bonini, S., Gabison, E. E., Jain, S., Knop, E., Markoulli, M., Ogawa, Y., Perez, V., Uchino, Y., Yokoi, N., Zoukhri, D. & Sullivan, D. A., 2017, (Accepted/In press) In : Ocular Surface.

Research output: Contribution to journalArticle

212 Citations (Scopus)
2016

Differential effect of rebamipide on transmembrane mucin biosynthesis in stratified ocular surface epithelial cells

Uchino, Y., Woodward, A. M. & Argüeso, P., 2016 Dec 1, In : Experimental Eye Research. 153, p. 1-7 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Impact of Cigarette Smoking on Tear Function and Correlation between Conjunctival Goblet Cells and Tear MUC5AC Concentration in Office Workers

Uchino, Y., Uchino, M., Yokoi, N., Dogru, M., Kawashima, M., Komuro, A., Sonomura, Y., Kato, H., Argüeso, P., Kinoshita, S. & Tsubota, K., 2016 Jun 14, In : Scientific Reports. 6, 27699.

Research output: Contribution to journalArticle

10 Citations (Scopus)

The association of sleep quality with dry eye disease: The Osaka study

Kawashima, M., Uchino, M., Yokoi, N., Uchino, Y., Dogru, M., Komuro, A., Sonomura, Y., Kato, H., Kinoshita, S. & Tsubota, K., 2016 Jun 1, In : Clinical Ophthalmology. 10, p. 1015-1021 7 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2015

Alteration of galectin-3 in tears of patients with dry eye disease

Uchino, Y., Mauris, J., Woodward, A. M., Dieckow, J., Amparo, F., Dana, R., Mantelli, F. & Argüeso, P., 2015 Jun 1, In : American Journal of Ophthalmology. 159, 6, p. 1027-1035.e3

Research output: Contribution to journalArticle

23 Citations (Scopus)

Associations between subjective happiness and dry eye disease: A new perspective from the Osaka study

Kawashima, M., Uchino, M., Yokoi, N., Uchino, Y., Dogru, M., Komuro, A., Sonomura, Y., Kato, H., Kinoshita, S., Mimura, M. & Tsubota, K., 2015 Apr 1, In : PLoS One. 10, 4, e0123299.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Galectin-3 as a regulator of the epithelial junction: Implications to wound repair and cancer

Argüeso, P., Mauris, J. & Uchino, Y., 2015 Jul 3, In : Tissue Barriers. 3, 3, p. 1-6 6 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Importance of tear film instability in dry eye disease in office workers using visual display terminals: The osaka study

Yokoi, N., Uchino, M., Uchino, Y., Dogru, M., Kawashima, M., Komuro, A., Sonomura, Y., Kato, H., Tsubota, K. & Kinoshita, S., 2015 Apr 1, In : American Journal of Ophthalmology. 159, 4, p. 748-754 7 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)
2014

Alteration of tear mucin 5AC in office workers using visual display terminals: The Osaka study

Uchino, Y., Uchino, M., Yokoi, N., Dogru, M., Kawashima, M., Okada, N., Inaba, T., Tamaki, S., Komuro, A., Sonomura, Y., Kato, H., Argüeso, P., Kinoshita, S. & Tsubota, K., 2014 Aug, In : JAMA Ophthalmology. 132, 8, p. 985-992 8 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Dry eye disease and work productivity loss in visual display users: The Osaka study

Uchino, M., Uchino, Y., Dogru, M., Kawashima, M., Yokoi, N., Komuro, A., Sonomura, Y., Kato, H., Kinoshita, S., Schaumberg, D. A. & Tsubota, K., 2014 Feb 1, In : American Journal of Ophthalmology. 157, 2, p. 294-300 7 p.

Research output: Contribution to journalArticle

75 Citations (Scopus)

Dry-eye screening by using a functional visual acuity measurement system: The Osaka study

Kaido, M., Uchino, M., Yokoi, N., Uchino, Y., Dogru, M., Kawashima, M., Komuro, A., Sonomura, Y., Kato, H., Kinoshita, S. & Tsubota, K., 2014 May 6, In : Investigative Ophthalmology and Visual Science. 55, 5, p. 3275-3281 7 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

The association between dry eye disease and physical activity as well as sedentary behavior: Results from the Osaka study

Kawashima, M., Uchino, M., Yokoi, N., Uchino, Y., Dogru, M., Komuro, A., Sonomura, Y., Kato, H., Nishiwaki, Y., Kinoshita, S. & Tsubota, K., 2014, In : Journal of Ophthalmology. 2014, 943786.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2013

Prevalence of dry eye disease and its risk factors in visual display terminal users: The Osaka study

Uchino, M., Yokoi, N., Uchino, Y., Dogru, M., Kawashima, M., Komuro, A., Sonomura, Y., Kato, H., Kinoshita, S., Schaumberg, D. A. & Tsubota, K., 2013 Oct, In : American Journal of Ophthalmology. 156, 4, p. 759-766.e1

Research output: Contribution to journalArticle

131 Citations (Scopus)

The impact of tear functions on visual outcome following keratoplasty in eyes with keratoconus

Hara, S., Kojima, T., Dogru, M., Uchino, Y., Goto, E., Matsumoto, Y., Kawakita, T., Tsubota, K. & Shimazaki, J., 2013 Jul 1, In : Graefe's Archive for Clinical and Experimental Ophthalmology. 251, 7, p. 1763-1770 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2012

[A quality of life questionnaire for Japanese allergic conjunctival disease].

Fukagawa, K., Fujishima, H., Fukushima, A., Sumi, T., Okamoto, S., Shoji, J., Satake, Y., Ohno, S., Namba, K., Kitaichi, N., Ebihara, N., Takahashi, H., Kumagai, N., Uchino, Y., Uchino, M., Murayama, K., Sakata, M., Uchio, E., Takamura, E., Ohashi, Y. & 2 others, Ohkubo, K. & Satoh, T., 2012 May, In : Nippon Ganka Gakkai zasshi. 116, 5, p. 494-502 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

A new mouse model of dry eye disease: Oxidative stress affects functional decline in the Lacrimal Gland

Uchino, Y., Kawakita, T., Ishii, T., Ishii, N. & Tsubota, K., 2012 Nov 1, In : Cornea. 31, 11 SUPPL.1, p. S63-S67

Research output: Contribution to journalArticle

36 Citations (Scopus)

Changes in dry eye diagnostic status following implementation of revised Japanese dry eye diagnostic criteria

Uchino, Y., Uchino, M., Dogru, M., Ward, S., Yokoi, N. & Tsubota, K., 2012 Jan 1, In : Japanese Journal of Ophthalmology. 56, 1, p. 8-13 6 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)
26 Citations (Scopus)

Improvement of accommodation with anti-oxidant supplementation in visual display terminal users

Uchino, Y., Uchino, M., Dogru, M., Fukagawa, K. & Tsubota, K., 2012, In : Journal of Nutrition, Health and Aging. 16, 5, p. 478-481 4 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Mitochondrial superoxide anion overproduction in Tet-mev-1 transgenic mice accelerates age-dependent corneal cell dysfunctions

Onouchi, H., Ishii, T., Miyazawa, M., Uchino, Y., Yasuda, K., Hartman, P. S., Kawai, K., Tsubota, K. & Ishii, N., 2012 Aug 1, In : Investigative Ophthalmology and Visual Science. 53, 9, p. 5780-5787 8 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Oxidative Stress Induced Inflammation Initiates Functional Decline of Tear Production

Uchino, Y., Kawakita, T., Miyazawa, M., Ishii, T., Onouchi, H., Yasuda, K., Ogawa, Y., Shimmura, S., Ishii, N. & Tsubota, K., 2012 Oct 5, In : PloS one. 7, 10, e45805.

Research output: Contribution to journalArticle

58 Citations (Scopus)

The antiaging approach for the treatment of dry eye

Tsubota, K., Kawashima, M., Inaba, T., Dogru, M., Matsumoto, Y., Ishida, R., Kaido, M., Kojima, T., Uchino, M., Uchino, Y., Ogawa, Y., Nakamura, S., Higuchi, A., Shinmura, K., Watanabe, M. & Kawakita, T., 2012 Nov 1, In : Cornea. 31, 11 SUPPL.1, p. S3-S8

Research output: Contribution to journalArticle

24 Citations (Scopus)
2011

[Risk factors of severe peripheral corneal ulcers].

Suzuki, A., Matsumoto, Y., Uchino, Y., Kawakita, T., Shimmura, S. & Tsubota, K., 2011 Feb 1, In : Nippon Ganka Gakkai zasshi. 115, 2, p. 116-121 6 p.

Research output: Contribution to journalArticle

Comparison of corneal thickness and haze in DSAEK and penetrating keratoplasty

Uchino, Y., Shimmura, S., Yamaguchi, T., Kawakita, T., Matsumoto, Y., Negishi, K. & Tsubota, K., 2011 Mar 1, In : Cornea. 30, 3, p. 287-290 4 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)
2010

Comparison of anterior and posterior corneal surface irregularity in descemet stripping automated endothelial keratoplasty and penetrating keratoplasty

Yamaguchi, T., Negishi, K., Yamaguchi, K., Dogru, M., Uchino, Y., Shimmura, S. & Tsubota, K., 2010 Oct 1, In : Cornea. 29, 10, p. 1086-1090 5 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)
2009
1 Citation (Scopus)

Dry eye disease in Japan: An epidemiologic study

Uchino, M., Uchino, Y., Dogru, M., Schaumberg, D. A. & Tsubota, K., 2009 Dec 1, In : Cornea. 28, SUPPL. 1, p. S31-S34

Research output: Contribution to journalArticle

2 Citations (Scopus)

Effect of anterior and posterior corneal surface irregularity on vision after Descemet-stripping endothelial keratoplasty

Yamaguchi, T., Negishi, K., Yamaguchi, K., Murat, D., Uchino, Y., Shimmura, S. & Tsubota, K., 2009 Apr 1, In : Journal of Cataract and Refractive Surgery. 35, 4, p. 688-694 7 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)
2008

Japan Ministry of Health Study on Prevalence of Dry Eye Disease Among Japanese High School Students

Uchino, M., Dogru, M., Uchino, Y., Fukagawa, K., Shimmura, S., Takebayashi, T., Schaumberg, D. A. & Tsubota, K., 2008 Dec, In : American Journal of Ophthalmology. 146, 6, p. 925-929.e2

Research output: Contribution to journalArticle

55 Citations (Scopus)

Management of Evaporative Dry Eye in Ectrodactyly-Ectodermal Dysplasia-Clefting Syndrome

Ota, Y., Matsumoto, Y., Dogru, M., Goto, E., Uchino, Y., Endo, K. & Tsubota, K., 2008 Sep, In : Optometry and Vision Science. 85, 9, p. E795-E801

Research output: Contribution to journalArticle

8 Citations (Scopus)

Prevalence of Dry Eye Disease among Japanese Visual Display Terminal Users

Uchino, M., Schaumberg, D. A., Dogru, M., Uchino, Y., Fukagawa, K., Shimmura, S., Satoh, T., Takebayashi, T. & Tsubota, K., 2008 Nov 1, In : Ophthalmology. 115, 11, p. 1982-1988 7 p.

Research output: Contribution to journalArticle

170 Citations (Scopus)
2007
33 Citations (Scopus)

The application of in vivo confocal scanning laser microscopy in the management of Acanthamoeba keratitis

Matsumoto, Y., Dogru, M., Sato, E. A., Katono, Y., Uchino, Y., Shimmura, S. & Tsubota, K., 2007 Jul 25, In : Molecular vision. 13, p. 1319-1326 8 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)
2006

Collagen-immobilized poly(vinyl alcohol) as an artificial cornea scaffold that supports a stratified corneal epithelium

Miyashita, H., Shimmura, S., Kobayashi, H., Taguchi, T., Asano-Kato, N., Uchino, Y., Kato, M., Shimazaki, J., Tanaka, J. & Tsubota, K., 2006 Jan 1, In : Journal of Biomedical Materials Research - Part B Applied Biomaterials. 76, 1, p. 56-63 8 p.

Research output: Contribution to journalArticle

62 Citations (Scopus)

Long-standing Bullous Keratopathy Is Associated with Peripheral Conjunctivalization and Limbal Deficiency

Uchino, Y., Goto, E., Takano, Y., Dogru, M., Shinozaki, N., Shimmura, S., Yagi, Y., Tsubota, K. & Shimazaki, J., 2006 Jul 1, In : Ophthalmology. 113, 7, p. 1098-1101 4 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Microkeratome assisted deep lamellar keratoprosthesis

Shimmura, S., Miyashita, H., Uchino, Y., Taguchi, T., Kobayashi, H., Shimazaki, J., Tanaka, J. & Tsubota, K., 2006 Jul 1, In : British Journal of Ophthalmology. 90, 7, p. 826-829 4 p.

Research output: Contribution to journalArticle

The features of dry eye disease in a Japanese elderly population

Uchino, M., Dogru, M., Yagi, Y., Goto, E., Tomita, M., Kon, T., Saiki, M., Matsumoto, Y., Uchino, Y., Yokoi, N., Kinoshita, S. & Tsubota, K., 2006 Nov 1, In : Optometry and Vision Science. 83, 11, p. 797-802 6 p.

Research output: Contribution to journalArticle

105 Citations (Scopus)
2004

A case of occult macular dystrophy

Uchino, Y., Hotta, K. & Hida, T., 2004 Aug 19, In : Folia Ophthalmologica Japonica. 55, 5, p. 398-402 5 p.

Research output: Contribution to journalArticle

Pars plana vitrectomy without long-acting gas tamponade for primary rhegmatogenous retinal detachment

Hotta, K., Sugitani, A. & Uchino, Y., 2004 Aug 4, In : Ophthalmologica. 218, 4, p. 270-273 4 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Vitreous surgery with air tamponade for retinal detachment with superiorly located retinal break

Uchino, Y. & Hotta, K., 2004 Aug 1, In : Japanese Journal of Clinical Ophthalmology. 58, 8, p. 1533-1537 5 p.

Research output: Contribution to journalArticle