β-Ketothioester as a reactive Knoevenagel donor

Yujiro Hayashi, Yuji Miyamoto, Mitsuru Shoji

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The Knoevenagel condensation of β-ketothioesters with various aldehydes proceeds efficiently, affording the condensation products in moderate to good yield even in cases where the reactions of the corresponding β-ketoesters give the adducts in only low to moderate yield.

Original languageEnglish
Pages (from-to)4079-4082
Number of pages4
JournalTetrahedron Letters
Volume43
Issue number22
DOIs
Publication statusPublished - 2002 May 27
Externally publishedYes

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Aldehydes
Condensation

Keywords

  • β-ketoester
  • β-ketothioester
  • Knoevenagel reaction

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

β-Ketothioester as a reactive Knoevenagel donor. / Hayashi, Yujiro; Miyamoto, Yuji; Shoji, Mitsuru.

In: Tetrahedron Letters, Vol. 43, No. 22, 27.05.2002, p. 4079-4082.

Research output: Contribution to journalArticle

Hayashi, Y, Miyamoto, Y & Shoji, M 2002, 'β-Ketothioester as a reactive Knoevenagel donor', Tetrahedron Letters, vol. 43, no. 22, pp. 4079-4082. https://doi.org/10.1016/S0040-4039(02)00675-5
Hayashi, Yujiro ; Miyamoto, Yuji ; Shoji, Mitsuru. / β-Ketothioester as a reactive Knoevenagel donor. In: Tetrahedron Letters. 2002 ; Vol. 43, No. 22. pp. 4079-4082.
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