Remote stereocontrol is a difficult topic in current organic synthesis. We have developed a highly diastereoselective 1,4-asymmetric induction using a cobalt alkyne complex. This is the first example of using a cobalt alkyne complex for a stereoselective reaction via 1,4-chelation. Both anti and syn isomers were stereoselectively synthesized using two different methods.
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry
- Inorganic Chemistry