4.14 Reactions using Thioamide and Allylic Cyanide

N. Kumagai

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Abstract

Catalytic asymmetric carbon-carbon bond-forming reactions in which thioamide and allylic cyanide functionalities play a central role are reviewed. These two functionalities share a characteristic property of a soft Lewis base, which is a key to the chemoselective activation triggering the reaction. Recent advances in cooperative catalysis allow for the implementation of this emerging class of substrates in a series of catalytic asymmetric carbon-carbon bond-forming reactions under proton transfer conditions.

Original languageEnglish
Title of host publicationSynthetic Methods III - Catalytic Methods
Subtitle of host publicationC-C Bond Formation
PublisherElsevier Ltd
Pages293-302
Number of pages10
Volume4
ISBN (Print)9780080951683
DOIs
Publication statusPublished - 2012 Sep
Externally publishedYes

Keywords

  • Cooperative catalysis
  • Hard Brnsted
  • Soft Lewis acid

ASJC Scopus subject areas

  • Chemistry(all)

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