Find Research outputs

Search results

• 2021

  Cholesterol-functionalized DNA/RNA heteroduplexes cross the blood–brain barrier and knock down genes in the rodent CNS

  Nagata, T., Dwyer, C. A., Yoshida-Tanaka, K., Ihara, K., Ohyagi, M., Kaburagi, H., Miyata, H., Ebihara, S., Yoshioka, K., Ishii, T., Miyata, K., Miyata, K., Powers, B., Igari, T., Yamamoto, S., Arimura, N., Hirabayashi, H., Uchihara, T., Hara, R. I., Wada, T. & 4 others, Bennett, C. F., Seth, P. P., Rigo, F. & Yokota, T., 2021, (Accepted/In press) In: Nature Biotechnology.

  Research output: Contribution to journal › Article › peer-review

• Chromosomal-scale de novo genome assemblies of Cynomolgus Macaque and Common Marmoset

  Jayakumar, V., Nishimura, O., Kadota, M., Hirose, N., Sano, H., Murakawa, Y., Yamamoto, Y., Nakaya, M., Tsukiyama, T., Seita, Y., Nakamura, S., Kawai, J., Sasaki, E., Ema, M., Kuraku, S., Kawaji, H. & Sakakibara, Y., 2021 Dec, In: Scientific Data. 8, 1, 159.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Chronic social defeat stress impairs goal-directed behavior through dysregulation of ventral hippocampal activity in male mice

  Yoshida, K., Drew, M. R., Kono, A., Mimura, M., Takata, N. & Tanaka, K. F., 2021 Aug, In: Neuropsychopharmacology. 46, 9, p. 1606-1616 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Cigarette smoke extract activates hypoxia-inducible factors in a reactive oxygen species-dependent manner in stroma cells from human endometrium

  Kida, N., Matsuo, Y., Hashimoto, Y., Nishi, K., Tsuzuki-Nakao, T., Bono, H., Maruyama, T., Hirota, K. & Okada, H., 2021 Jan, In: Antioxidants. 10, 1, p. 1-17 17 p., 48.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• Circadian clock regulates tear secretion in the lacrimal gland

  Vu, C. H. V., Kawashima, M., Nakamura, W., Nakamura, T. J. & Tsubota, K., 2021 May, In: Experimental Eye Research. 206, 108524.

  Research output: Contribution to journal › Article › peer-review

• Circadian rhythms in the tissue-specificity from metabolism to immunity; insights from omics studies

  Kinouchi, K., Mikami, Y., Kanai, T. & Itoh, H., 2021, (Accepted/In press) In: Molecular Aspects of Medicine. 100984.

  Research output: Contribution to journal › Article › peer-review

• Circulating trimethylamine N-oxide in association with diet and cardiometabolic biomarkers: an international pooled analysis

  Yang, J. J., Shu, X. O., Herrington, D. M., Moore, S. C., Meyer, K. A., Ose, J., Menni, C., Palmer, N. D., Eliassen, H., Harada, S., Tzoulaki, I., Zhu, H., Albanes, D., Wang, T. J., Zheng, W., Cai, H., Ulrich, C. M., Guasch-Ferré, M., Karaman, I., Fornage, M. & 6 others, Cai, Q., Matthews, C. E., Wagenknecht, L. E., Elliott, P., Gerszten, R. E. & Yu, D., 2021 May 8, In: The American journal of clinical nutrition. 113, 5, p. 1145-1156 12 p.

  Research output: Contribution to journal › Article › peer-review

• Cis-acting elements involved in the G2/M-phase-specific transcription of the cyclin B gene in the unicellular alga Cyanidioschyzon merolae

  Sumiya, N., 2021, (Accepted/In press) In: Journal of Plant Research.

  Research output: Contribution to journal › Article › peer-review

• Classification of Genus-1 Holomorphic Lefschetz Pencils

  Hamada, N. & Hayano, K., 2021, In: Turkish Journal of Mathematics. 45, 3, p. 1079-1119 41 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Classification Tree Analysis Based On Machine Learning for Predicting Linezolid-Induced Thrombocytopenia

  Takahashi, S., Tsuji, Y., Kasai, H., Ogami, C., Kawasuji, H., Yamamoto, Y. & To, H., 2021 May, In: Journal of Pharmaceutical Sciences. 110, 5, p. 2295-2300 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Classroom-based cognitive behavioural therapy: a large-scale non-randomised controlled trial of the ‘Journey of the Brave’

  Urao, Y., Ohira, I., Koshiba, T., Ishikawa, S. I., Sato, Y. & Shimizu, E., 2021 Dec, In: Child and Adolescent Psychiatry and Mental Health. 15, 1, 21.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Clinical, Endoscopic, and Pathological Characteristics of Immune Checkpoint Inhibitor-Induced Gastroenterocolitis

  Hayashi, Y., Hosoe, N., Takabayashi, K., Limpias Kamiya, K. J. L., Tsugaru, K., Shimozaki, K., Hirata, K., Fukuhara, K., Fukuhara, S., Mutaguchi, M., Sujino, T., Sukawa, Y., Hamamoto, Y., Naganuma, M., Takaishi, H., Shimoda, M., Ogata, H. & Kanai, T., 2021 Jun, In: Digestive Diseases and Sciences. 66, 6, p. 2129-2134 6 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Clinical and biomarker profiles and prognosis of elderly patients with coronavirus disease 2019 (COVID-19) with cardiovascular diseases and/or risk factors

  Matsumoto, S., Kuroda, S., Sano, T., Kitai, T., Yonetsu, T., Kohsaka, S., Torii, S., Kishi, T., Komuro, I., Hirata, K. I., Node, K. & Matsue, Y., 2021, In: Circulation Journal. 85, 6, p. 921-928 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• Clinical and Immunological Analyses of Ten Patients with MIRAGE Syndrome

  Mitsui-Sekinaka, K., Narumi, S., Sekinaka, Y., Uematsu, K., Yoshida, Y., Amano, N., Shima, H., Hasegawa, T. & Nonoyama, S., 2021 Apr, In: Journal of Clinical Immunology. 41, 3, p. 709-711 3 p.

  Research output: Contribution to journal › Letter › peer-review

• Clinical application of diffusion tensor tractography to postoperative C5 palsy

  Takano, M., Tsuji, O., Fujiyoshi, K., Nagoshi, N., Nori, S., Suzuki, S., Okada, E., Yagi, M., Matsumoto, M., Nakamura, M. & Watanabe, K., 2021 Dec, In: Spinal Cord Series and Cases. 7, 1, 83.

  Research output: Contribution to journal › Article › peer-review

• Clinical Characteristics and Outcomes Associated With Oral Anticoagulant Use Among Patients Hospitalized With Intracerebral Hemorrhage

  Xian, Y., Zhang, S., Inohara, T., Grau-Sepulveda, M., Matsouaka, R. A., Peterson, E. D., Piccini, J. P., Smith, E. E., Sheth, K. N., Bhatt, D. L., Fonarow, G. C. & Schwamm, L. H., 2021 Feb 1, In: JAMA network open. 4, 2, p. e2037438

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• Clinical characteristics of patients with not well-controlled severe asthma in Japan: Analysis of the Keio Severe Asthma Research Program in Japanese population (KEIO-SARP) registry

  Tanosaki, T., Kabata, H., Matsusaka, M., Miyata, J., Masaki, K., Mochimaru, T., Okuzumi, S., Kuwae, M., Watanabe, R., Suzuki, Y., Sayama, K., Izuhara, K., Asano, K. & Fukunaga, K., 2021 Jan, In: Allergology International. 70, 1, p. 61-67 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Clinical efficacy and safety of combination therapy of tocilizumab and steroid pulse therapy for critical COVID-19 in HD patients

  Toda, M., Fujii, K., Yoshifuji, A., Kondo, Y., Itoh, K., Sekine, K., Kikuchi, T. & Ryuzaki, M., 2021, (Accepted/In press) In: Clinical and experimental nephrology.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Clinical features and outcomes of patients with stage I multiple primary lung cancers

  The Japanese Joint Committee of Lung Cancer Registry, 2021 May, In: Cancer science. 112, 5, p. 1924-1935 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Clinical Features and Prognosis of Nontuberculous Mycobacterial Pleuritis

  on behalf of the Nontuberculous Mycobacteriosis and Bronchiectasis–Japan Research Consortium (NTM-JRC), 2021 Sep, In: Annals of the American Thoracic Society. 18, 9, p. 1490-1497 8 p.

  Research output: Contribution to journal › Article › peer-review

• Clinical features and prognostic impact of coexisting autoimmune disease other than myasthenia gravis in resected thymomas: Analysis of a Japanese multi-institutional retrospective database

  Hishida, T., Asamura, H., Yoshida, K., Tsuboi, M., Yokoi, K., Toyooka, S., Matsumura, A., Tagawa, T. & Okumura, M., 2021 Mar 1, In: European Journal of Cardio-thoracic Surgery. 59, 3, p. 641-649 9 p.

  Research output: Contribution to journal › Article › peer-review

• Clinical impact of intraoperative bile leakage during laparoscopic liver resection

  Hayashi, K., Abe, Y., Shinoda, M., Kitago, M., Yagi, H., Oshima, G., Hori, S., Wakabayashi, T. & Kitagawa, Y., 2021 Aug, In: Surgical endoscopy. 35, 8, p. 4134-4142 9 p.

  Research output: Contribution to journal › Article › peer-review

• Clinical Impact of Portal Vein Distance on Computed Tomography for Postoperative Pancreatic Fistula after Pancreatoduodenectomy

  Endo, Y., Kitago, M., Shinoda, M., Yagi, H., Abe, Y., Oshima, G., Hori, S., Yokose, T., Abe, K., Takemura, R., Ishi, R. & Kitagawa, Y., 2021 Jul, In: World Journal of Surgery. 45, 7, p. 2200-2209 10 p.

  Research output: Contribution to journal › Article › peer-review

• Clinical Impacts of EGFR Mutation Status: Analysis of 5780 Surgically Resected Lung Cancer Cases

  The Japanese Joint Committee of Lung Cancer Registry, 2021 Jan, In: Annals of Thoracic Surgery. 111, 1, p. 269-276 8 p.

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)

• Clinical observation of allergic conjunctival diseases with portable and recordable slit-lamp device

  Yazu, H., Shimizu, E., Sato, S., Aketa, N., Katayama, T., Yokoiwa, R., Sato, Y., Fukagawa, K., Ogawa, Y., Tsubota, K. & Fujishima, H., 2021 Mar, In: Diagnostics. 11, 3, 535.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Clinical outcome of patients with recurrent or refractory localized Ewing's sarcoma family of tumors: A retrospective report from the Japan Ewing Sarcoma Study Group

  Japan Ewing Sarcoma Study Group, 2021 Jun, In: Cancer Reports. 4, 3, e1329.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Clinical outcomes according to dose reduction criteria of apixaban in Japanese elderly patients with atrial fibrillation: J-ELD AF Registry subanalysis

  J-ELD AF Investigators, 2021, (Accepted/In press) In: Heart and vessels.

  Research output: Contribution to journal › Article › peer-review

• Clinical outcomes after clozapine discontinuation in responders versus nonresponders: A retrospective chart review

  Watanabe, M., Misawa, F., Miura, G., Fujii, Y. & Takeuchi, H., 2021, (Accepted/In press) In: International clinical psychopharmacology. p. 188-192 5 p.

  Research output: Contribution to journal › Article › peer-review

• Clinical outcomes and a therapeutic indication of intramedullary spinal cord astrocytoma

  Nagoshi, N., Tsuji, O., Suzuki, S., Nori, S., Yagi, M., Okada, E., Okita, H., Fujita, N., Ishii, K., Matsumoto, M., Nakamura, M. & Watanabe, K., 2021, (Accepted/In press) In: Spinal Cord.

  Research output: Contribution to journal › Article › peer-review

• Clinical outcomes of KeraVio using violet light: Emitting glasses and riboflavin drops for corneal ectasia: A pilot study

  Kobashi, H., Torii, H., Toda, I., Kondo, S., Itoi, M. & Tsubota, K., 2021 Oct 1, In: British Journal of Ophthalmology. 105, 10, p. 1376-1382 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• Clinical practice guidance for next-generation sequencing in cancer diagnosis and treatment (edition 2.1)

  Japanese Society of Medical Oncology, Japan Society of Clinical Oncology & Japanese Cancer Association, 2021 Feb, In: International Journal of Clinical Oncology. 26, 2, p. 233-283 51 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  6 Citations (Scopus)

• Clinical practice guidelines for biliary atresia in Japan: A secondary publication of the abbreviated version translated into English

  The Japanese Biliary Atresia Society, 2021 Jan, In: Journal of Hepato-Biliary-Pancreatic Sciences. 28, 1, p. 55-61 7 p.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Clinical remission of rheumatoid arthritis in a multicenter real-world study in Asia-Pacific region

  on behalf of APLAR RA SIG group, 2021 Oct, In: The Lancet Regional Health - Western Pacific. 15, 100240.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Clinical results of a massive blood transfusion protocol for postpartum hemorrhage in a university hospital in japan: A retrospective study

  Ochiai, D., Abe, Y., Yamazaki, R., Uemura, T., Toriumi, A., Matsuhashi, H., Tanaka, Y., Ikenoue, S., Kasuga, Y., Tanosaki, R. & Tanaka, M., 2021 Sep, In: Medicina (Lithuania). 57, 9, 983.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Clinical risk model for predicting 1-year mortality after transcatheter aortic valve replacement

  Yamamoto, M., Otsuka, T., Shimura, T., Yamaguchi, R., Adachi, Y., Kagase, A., Tokuda, T., Yashima, F., Watanabe, Y., Tada, N., Naganuma, T., Araki, M., Yamanaka, F., Mizutani, K., Tabata, M., Watanabe, S., Sato, Y., Ueno, H., Takagi, K., Higashimori, A. & 2 others, Shirai, S. & Hayashida, K., 2021 Mar, In: Catheterization and Cardiovascular Interventions. 97, 4, p. E544-E551

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Clinical Significance of Guanylate Cyclase Stimulator, Riociguat, on Right Ventricular Functional Improvement in Patients with Pulmonary Hypertension

  Murata, M., Kawakami, T., Kataoka, M., Moriyama, H., Hiraide, T., Kimura, M., Endo, J., Kohno, T., Itabashi, Y. & Fukuda, K., 2021 Jan, In: Cardiology (Switzerland). 146, 1, p. 130-136 7 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Clinical Significance of Pretherapeutic Serum Squamous Cell Carcinoma Antigen Level in Patients with Neoadjuvant Chemotherapy for Esophageal Squamous Cell Carcinoma

  Okamura, A., Matsuda, S., Mayanagi, S., Kanamori, J., Imamura, Y., Irino, T., Kawakubo, H., Mine, S., Takeuchi, H., Kitagawa, Y. & Watanabe, M., 2021 Feb, In: Annals of Surgical Oncology. 28, 2, p. 1209-1216 8 p.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• Clinical spectrum of individuals with de novo EBF3 variants or deletions

  Nishi, E., Uehara, T., Yanagi, K., Hasegawa, Y., Ueda, K., Kaname, T., Yamamoto, T., Kosaki, K. & Okamoto, N., 2021 Oct, In: American Journal of Medical Genetics, Part A. 185, 10, p. 2913-2921 9 p.

  Research output: Contribution to journal › Article › peer-review

• Clinical usefulness of sputum culture on the first postoperative day to predict early postoperative pneumonia after esophagectomy for esophageal cancer

  Matsui, K., Kawakubo, H., Matsuda, S., Mayanagi, S., Irino, T., Fukuda, K., Nakamura, R., Wada, N. & Kitagawa, Y., 2021 Oct, In: Esophagus. 18, 4, p. 773-782 10 p.

  Research output: Contribution to journal › Article › peer-review

• Clinical utility of 1-month postpartum random plasma glucose and glycated hemoglobin combined with pre-pregnancy body mass index for detecting postpartum glucose intolerance in Japanese women with gestational diabetes

  Sugiyama, K., Saisho, Y., Kasuga, Y., Ochiai, D. & Itoh, H., 2021, (Accepted/In press) In: Journal of Diabetes Investigation.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Clinical utility of SARS-CoV-2 whole genome sequencing in deciphering source of infection

  Keio Donner Project, 2021 Jan, In: Journal of Hospital Infection. 107, p. 40-44 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  5 Citations (Scopus)

• Clinical utility of the Vesical Imaging-Reporting and Data System for muscle-invasive bladder cancer between radiologists and urologists based on multiparametric MRI including 3D FSE T2-weighted acquisitions

  Arita, Y., Shigeta, K., Akita, H., Suzuki, T., Kufukihara, R., Kwee, T. C., Ishii, R., Mikami, S., Okuda, S., Kikuchi, E., Oya, M. & Jinzaki, M., 2021 Feb, In: European radiology. 31, 2, p. 875-883 9 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Clinicopathological and prognostic features of operable non-small cell lung cancer patients with diabetes mellitus

  Kaseda, K., Hishida, T., Masai, K., Asakura, K., Hayashi, Y. & Asamura, H., 2021 Jan, In: Journal of Surgical Oncology. 123, 1, p. 332-341 10 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Clinicopathological characteristics, practical treatments, prognosis, and clinical issues of older breast cancer patients in Japan

  Sawaki, M., Yamada, A., Kumamaru, H., Miyata, H., Nakayama, K., Shimizu, C., Miyashita, M., Honma, N., Taira, N. & Saji, S., 2021 Jan, In: Breast Cancer. 28, 1

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Clinicopathological characteristics and prognostic factors of ovarian granulosa cell tumors: A JSGO-JSOG joint study

  Ebina, Y., Yamagami, W., Kobayashi, Y., Tabata, T., Kaneuchi, M., Nagase, S., Enomoto, T. & Mikami, M., 2021, (Accepted/In press) In: Gynecologic Oncology.

  Research output: Contribution to journal › Article › peer-review

• Clinicopathological characteristics of lymphoproliferative disorders in 232 patients with rheumatoid arthritis in Japan: A retrospective, multicenter, descriptive study

  Takada, H., Kaneko, Y., Nakano, K., Tanaka, M., Fujii, T., Saito, K., Sugimoto, N., Sasaki, S., Saito, S., Saito, R., Kuramoto, N., Harigai, M. & Suzuki, Y., 2021, (Accepted/In press) In: Modern rheumatology.

  Research output: Contribution to journal › Article › peer-review

• Clinicopathological impacts of DNA methylation alterations on pancreatic ductal adenocarcinoma: prediction of early recurrence based on genome-wide DNA methylation profiling

  Endo, Y., Fujimoto, M., Ito, N., Takahashi, Y., Kitago, M., Gotoh, M., Hiraoka, N., Yoshida, T., Kitagawa, Y., Kanai, Y. & Arai, E., 2021 May, In: Journal of Cancer Research and Clinical Oncology. 147, 5, p. 1341-1354 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Closing gigantic left atrial appendage using a LAmbre Closure System: First implant experience in North America

  Inohara, T., Tsang, M. Y., Lee, C. & Saw, J., 2021 Jan, In: Journal of Cardiovascular Electrophysiology. 32, 1, p. 158-161 4 p.

  Research output: Contribution to journal › Article › peer-review

• Closure of gastric perforations during endoluminal resection using a novel biodegradable collagen sol: A feasibility survival study on porcine model (with video)

  Uraoka, T., Yunoki, S., Sasaki, M., Kinoshita, S., Takatori, Y., Hirai, Y., Narita, T., Ramberan, H., Shimoda, M. & Yahagi, N., 2021, (Accepted/In press) In: Digestive Endoscopy.

  Research output: Contribution to journal › Article › peer-review

• Closure of macular hole secondary to ischemic hemi-central retinal vein occlusion by retinal photocoagulation and topical anti-inflammatory treatment

  Asato, T., Nagai, N., Suzuki, M., Uchida, A., Kurihara, T., Ban, N., Minami, S., Shinoda, H., Tsubota, K. & Ozawa, Y., 2021 Mar, In: Lasers in Medical Science. 36, 2, p. 469-471 3 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access