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  Tissue culture methods to study neurological disorders: Establishment of immortalized Schwann cells from murine disease models

  Watabe, K., Sakamoto, T., Kawazoe, Y., Michikawa, M., Miyamoto, K., Yamamura, T., Saya, H. & Araki, N., 2003 Mar, In: Neuropathology. 23, 1, p. 68-78 11 p.

  Research output: Contribution to journal › Article › peer-review
  24 Citations (Scopus)

• Tissue damage of different submucosal injection solutions for EMR

  Fujishiro, M., Yahagi, N., Kashimura, K., Matsuura, T., Nakamura, M., Kakushima, N., Kodashima, S., Ono, S., Kobayashi, K., Hashimoto, T., Yamamichi, N., Tateishi, A., Shimizu, Y., Oka, M., Ichinose, M. & Omata, M., 2005 Dec, In: Gastrointestinal Endoscopy. 62, 6, p. 933-942 10 p.

  Research output: Contribution to journal › Article › peer-review
  125 Citations (Scopus)

• Tissue distribution and action of basic drug biperiden

  Yokogawa, K., Ishizaki, J., Nakashima, E., Ichimura, F., Hasegawa, M., Kido, H. & Yamaguchi, N., 1990, In: Journal of Pharmacobio-Dynamics. 13, 4, p. s-84

  Research output: Contribution to journal › Article › peer-review

• Tissue engineering of skeletal muscle in collagen gel

  Kishi, K., Satoh, H., Tanaka, T., Kubota, Y., Koyama, T., Imanishi, N., Nakajima, H. & Nakajima, T., 2004 Sep, In: Japanese Journal of Plastic and Reconstructive Surgery. 47, 9, p. 1001-1005 5 p.

  Research output: Contribution to journal › Article › peer-review

• Tissue engineering of the intervertebral disc with cultured nucleus pulposus cells using atelocollagen scaffold and growth factors

  Lee, K. I., Moon, S. H., Kim, H., Kwon, U. H., Kim, H. J., Park, S. N., Suh, H., Lee, H. M., Kim, H. S., Chun, H. J., Kwon, I. K. & Jang, J. W., 2012 Mar 15, In: Spine. 37, 6, p. 452-458 7 p.

  Research output: Contribution to journal › Article › peer-review
  46 Citations (Scopus)

• Tissue inhibitor of metalloproteinase 1 is a negative regulator of the metastatic ability of a human gastric cancer cell line, KKLS, in the chick embryo

  Tsuchiya, Y., Sato, H., Endo, Y., Okada, Y., Mai, M., Sasaki, T. & Seiki, M., 1993 Mar 15, In: Cancer Research. 53, 6, p. 1397-1402 6 p.

  Research output: Contribution to journal › Article › peer-review
  110 Citations (Scopus)

• Tissue-limited ring chromosome 18 mosaicism as a cause of Pitt-Hopkins syndrome

  Takenouchi, T., Yagihashi, T., Tsuchiya, H., Torii, C., Hayashi, K., Kosaki, R., Saitoh, S., Takahashi, T. & Kosaki, K., 2012 Oct, In: American Journal of Medical Genetics, Part A. 158 A, 10, p. 2621-2623 3 p.

  Research output: Contribution to journal › Article › peer-review
  8 Citations (Scopus)

• Tissue Myeloid Progenitors Differentiate into Pericytes through TGF-β Signaling in Developing Skin Vasculature

  Yamazaki, T., Nalbandian, A., Uchida, Y., Li, W., Arnold, T. D., Kubota, Y., Yamamoto, S., Ema, M. & Mukouyama, Y. S., 2017 Mar 21, In: Cell Reports. 18, 12, p. 2991-3004 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  56 Citations (Scopus)

• Tissue regulatory T cells and neural repair

  Ito, M., Komai, K., Nakamura, T., Srirat, T. & Yoshimura, A., 2019 Feb 19, In: International immunology. 31, 6, p. 361-369 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  18 Citations (Scopus)

• Tissue renin-angiotensin system in lacrimal gland fibrosis in a murine model of chronic graft-versus-host disease

  Yaguchi, S., Ogawa, Y., Kawakita, T., Shimmura, S. & Tsubota, K., 2015 Oct 9, In: Cornea. 34, p. S142-S152

  Research output: Contribution to journal › Article › peer-review
  9 Citations (Scopus)

• Tissue-specific and ubiquitous gene knockouts by TALEN electroporation provide new approaches to investigating gene function in Ciona

  Treen, N., Yoshida, K., Sakuma, T., Sasaki, H., Kawai, N., Yamamoto, T. & Sasakura, Y., 2014 Jan 15, In: Development (Cambridge). 141, 2, p. 481-487 7 p.

  Research output: Contribution to journal › Article › peer-review
  60 Citations (Scopus)

• Tissue-Specific Distribution of DNA-Binding Nuclear Proteins

  Tamura, H. O., Natori, S. & Obinata, M., 1982, In: Differentiation. 23, 1-3, p. 87-90 4 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Tissue-specific expression and mapping of the Cox7ah gene in mouse

  Jaradat, S. A., Ko, M. S. H. & Grossman, L. I., 1998 May 1, In: Genomics. 49, 3, p. 363-370 8 p.

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)

• Tissue-specific expression of a FMR1/β-galactosidase fusion gene in transgenic mice

  Hergersberg, M., Matsuo, K., Gassmann, M., Schaffner, W., Lüscher, B., Rülicke, T. & Aguzzi, A., 1995 Mar, In: Human molecular genetics. 4, 3, p. 359-366 8 p.

  Research output: Contribution to journal › Article › peer-review
  66 Citations (Scopus)

• Tissue-specific expression of mouse tyrosinase gene in cultured chicken cells

  Akiyama, T., Whitaker, B., Federspiel, M., Hughes, S. H., Yamamoto, H., Takeuchi, T. & Brumbaugh, J., 1994 Sep, In: Experimental Cell Research. 214, 1, p. 154-162 9 p.

  Research output: Contribution to journal › Article › peer-review
  13 Citations (Scopus)

• Tissue-specific in vitro transcription from the mouse myelin basic protein promoter

  Tamura, T. A., Aoyama, A., Inoue, T., Miura, M., Okano, H. & Mikoshiba, K., 1989, In: Molecular and cellular biology. 9, 7, p. 3122-3126 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  54 Citations (Scopus)

• Tissue-Specific Macrophage Responses to Remote Injury Impact the Outcome of Subsequent Local Immune Challenge

  Hoyer, F. F., Naxerova, K., Schloss, M. J., Hulsmans, M., Nair, A. V., Dutta, P., Calcagno, D. M., Herisson, F., Anzai, A., Sun, Y., Wojtkiewicz, G., Rohde, D., Frodermann, V., Vandoorne, K., Courties, G., Iwamoto, Y., Garris, C. S., Williams, D. L., Breton, S., Brown, D., & 7 othersWhalen, M., Libby, P., Pittet, M. J., King, K. R., Weissleder, R., Swirski, F. K. & Nahrendorf, M., 2019 Nov 19, In: Immunity. 51, 5, p. 899-914.e7

  Research output: Contribution to journal › Article › peer-review

  Open Access
  48 Citations (Scopus)

• Tissue-specific mutation accumulation in human adult stem cells during life

  Blokzijl, F., De Ligt, J., Jager, M., Sasselli, V., Roerink, S., Sasaki, N., Huch, M., Boymans, S., Kuijk, E., Prins, P., Nijman, I. J., Martincorena, I., Mokry, M., Wiegerinck, C. L., Middendorp, S., Sato, T., Schwank, G., Nieuwenhuis, E. E. S., Verstegen, M. M. A., Van Der Laan, L. J. W., & 8 othersDe Jonge, J., Ijzermans, J. N. M., Vries, R. G., Van De Wetering, M., Stratton, M. R., Clevers, H., Cuppen, E. & Van Boxtel, R., 2016, In: Nature. 538, 7624, p. 260-264 5 p.

  Research output: Contribution to journal › Article › peer-review
  475 Citations (Scopus)

• Tissue-type plasminogen activator of colonic mucosa in ulcerative colitis - Evidence of endothelium-derived fibrinolytic activation

  Kurose, I., Miura, S., Suematsu, M., Serizawa, H., Fukumura, D., Asako, H., Hibi, T. & Tsuchiya, M., 1992 Feb 1, In: Digestive Diseases and Sciences. 37, 2, p. 307-311 5 p.

  Research output: Contribution to journal › Article › peer-review
  9 Citations (Scopus)

• Titanium culture vessel capable of controlling culture temperature for evaluation of cell thermotolerance

  Imashiro, C., Ida, Y., Miyata, S. & Komotori, J., 2021, In: Zairyo/Journal of the Society of Materials Science, Japan. 70, 6, p. 479-485 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Titanium Culture Vessel Capable of Controlling Culture Temperature for Evaluation of Cell Thermotolerance

  Imashiro, C., Ida, Y., Miyata, S. & Komotori, J., 2022, In: Materials Transactions. 63, 3, p. 373-378 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• TKI dasatinib monotherapy for a patient with Ph-like ALL bearing ATF7IP/PDGFRB translocation

  Kobayashi, K., Miyagawa, N., Mitsui, K., Matsuoka, M., Kojima, Y., Takahashi, H., Ootsubo, K., Nagai, J., Ueno, H., Ishibashi, T., Sultana, S., Okada, Y., Akimoto, S., Okita, H., Matsumoto, K., Goto, H., Kiyokawa, N. & Ohara, A., 2015 Jun 1, In: Pediatric Blood and Cancer. 62, 6, p. 1058-1060 3 p.

  Research output: Contribution to journal › Article › peer-review
  50 Citations (Scopus)

• Tks5-dependent formation of circumferential podosomes/invadopodia mediates cell-cell fusion

  Oikawa, T., Oyama, M., Kozuka-Hata, H., Uehara, S., Udagawa, N., Saya, H. & Matsuo, K., 2012 May, In: Journal of Cell Biology. 197, 4, p. 553-568 16 p.

  Research output: Contribution to journal › Article › peer-review
  73 Citations (Scopus)

• TL‐10: A programming language for assembly robots

  Nakano, M., Hasegawa, J., Kuno, T., Moribe, H., Ikeda, T., Koide, M., Shiroshita, O. & Sukigara, K., 1985 Jan 1, In: Journal of Robotic Systems. 2, 3, p. 277-288 12 p.

  Research output: Contribution to journal › Article › peer-review

• TL1A produced by lamina propria macrophages induces Th1 and Th17 immune responses in cooperation with IL-23 in patients with Crohn's disease

  Kamada, N., Hisamatsu, T., Honda, H., Kobayashi, T., Chinen, H., Takayama, T., Kitazume, M. T., Okamoto, S., Koganei, K., Sugita, A., Kanai, T. & Hibi, T., 2010 Apr, In: Inflammatory bowel diseases. 16, 4, p. 568-575 8 p.

  Research output: Contribution to journal › Article › peer-review
  94 Citations (Scopus)

• TLR3 is an endogenous sensor of tissue necrosis during acute inflammatory events

  Cavassani, K. A., Ishii, M., Wen, H., Schaller, M. A., Lincoln, P. M., Lukacs, N. W., Hogaboam, C. M. & Kunkel, S. L., 2008 Oct 27, In: Journal of Experimental Medicine. 205, 11, p. 2609-2621 13 p.

  Research output: Contribution to journal › Article › peer-review
  359 Citations (Scopus)

• TLR3-mediated synthesis and release of Eotaxin-1/CCL11 from human bronchial smooth muscle cells stimulated with double-stranded RNA

  Niimi, K., Asano, K., Shiraishi, Y., Nakajima, T., Wakaki, M., Kagyo, J., Takihara, T., Suzuki, Y., Fukunaga, K., Shiomi, T., Oguma, T., Sayama, K., Yamaguchi, K., Natori, Y., Matsumoto, M., Seya, T., Yamaya, M. & Ishizaka, A., 2007 Jan 1, In: Journal of Immunology. 178, 1, p. 489-495 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  50 Citations (Scopus)

• TLR7 agonist suppresses group 2 innate lymphoid cell–mediated inflammation via IL-27–producing interstitial macrophages

  Okuzumi, S., Miyata, J., Kabata, H., Mochimaru, T., Kagawa, S., Masaki, K., Irie, M., Morita, H. & Fukunaga, K., 2021 Sep, In: American journal of respiratory cell and molecular biology. 65, 3, p. 309-318 10 p.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• TLR9 signalling in microglia attenuates seizure-induced aberrant neurogenesis in the adult hippocampus

  Matsuda, T., Murao, N., Katano, Y., Juliandi, B., Kohyama, J., Akira, S., Kawai, T. & Nakashima, K., 2015 Mar 9, In: Nature communications. 6, 6514.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  68 Citations (Scopus)

• TLR-dependent induction of IFN-β mediates host defense against Trypanosoma cruzi

  Koga, R., Hamano, S., Kuwata, H., Atarashi, K., Ogawa, M., Hisaeda, H., Yamamoto, M., Akira, S., Himeno, K., Matsumoto, M. & Takeda, K., 2006 Nov 15, In: Journal of Immunology. 177, 10, p. 7059-7066 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  74 Citations (Scopus)

• T lymphocyte subpopulations and immunoglobulin-containing cells in the colonic mucosa of ulcerative colitis; a morphometric and immunohistochemical study

  Kobayashi, K., Asakura, H., Hamada, Y., Hibi, T., Watanabe, M., Yoshida, T., Watanabe, N., Miura, S., Aiso, S. & Tsuchiya, M., 1988, In: Journal of Clinical and Laboratory Immunology. 25, 2, p. 63-68 6 p.

  Research output: Contribution to journal › Article › peer-review
  44 Citations (Scopus)

• TMR METHOD FOR IMPROVING YIELD OF LARGE MEMORY CHIPS.

  Takefuji, Y., Adachi, Y. & Aiso, H., 1982 Jan 1, In: Systems, computers, controls. 13, 1, p. 47-53 7 p.

  Research output: Contribution to journal › Article › peer-review

• TMS orientation for NIRS-functional motor mapping

  Akiyama, T., Ohira, T., Kawase, T. & Kato, T., 2006 Dec, In: Brain Topography. 19, 1-2, p. 1-9 9 p.

  Research output: Contribution to journal › Article › peer-review
  34 Citations (Scopus)

• TNF-/TNFR1 signaling promotes gastric tumorigenesis through induction of Noxo1 and Gna14 in tumor cells

  Oshima, H., Ishikawa, T., Yoshida, G. J., Naoi, K., Maeda, Y., Naka, K., Ju, X., Yamada, Y., Minamoto, T., Mukaida, N., Saya, H. & Oshima, M., 2014 Jul 17, In: Oncogene. 33, 29, p. 3820-3829 10 p.

  Research output: Contribution to journal › Article › peer-review
  84 Citations (Scopus)

• TNFAIP2 expression induces epithelial-to-mesenchymal transition and confers platinum resistance in urothelial cancer cells

  Niwa, N., Tanaka, N., Hongo, H., Miyazaki, Y., Takamatsu, K., Mizuno, R., Kikuchi, E., Mikami, S., Kosaka, T. & Oya, M., 2019 Nov 1, In: Laboratory Investigation. 99, 11, p. 1702-1713 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  7 Citations (Scopus)

• TNF-receptor associated factor 6-deficient fibroblast is sensitive to the TNF-α-induced cell death: Involvement of reactive oxygen species

  Ichikawa, D., Funakoshi-Tago, M., Aizu-Yokota, E., Sonoda, Y., Inoue, J. I. & Kasahara, T., 2006 Dec 8, In: Biochemical and Biophysical Research Communications. 351, 1, p. 93-98 6 p.

  Research output: Contribution to journal › Article › peer-review
  8 Citations (Scopus)

• Tnfrsf13b c.226g>a (p.gly76ser) as a novel causative mutation for pulmonary arterial hypertension

  Shinya, Y., Hiraide, T., Momoi, M., Goto, S., Suzuki, H., Katsumata, Y., Kurebayashi, Y., Endo, J., Sano, M., Fukuda, K., Kosaki, K. & Kataoka, M., 2021, In: Journal of the American Heart Association. 10, 5, p. 1-4 4 p., e019245.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• TNF-α-converting enzyme/A disintegrin and metalloprotease - 17 mediates mechanotransduction in murine tracheal epithelial cells

  Shiomi, T., Tschumperlin, D. J., Park, J. A., Sunnarborg, S. W., Horiuchi, K., Blobel, C. P. & Drazen, J. M., 2011 Aug 1, In: American journal of respiratory cell and molecular biology. 45, 2, p. 376-385 10 p.

  Research output: Contribution to journal › Article › peer-review
  21 Citations (Scopus)

• TNFα promotes osteosarcoma progression by maintaining tumor cells in an undifferentiated state

  Mori, T., Sato, Y., Miyamoto, K., Kobayashi, T., Shimizu, T., Kanagawa, H., Katsuyama, E., Fujie, A., Hao, W., Tando, T., Iwasaki, R., Kawana, H., Morioka, H., Matsumoto, M., Saya, H., Toyama, Y. & Miyamoto, T., 2014 Aug 14, In: Oncogene. 33, 33, p. 4236-4241 6 p.

  Research output: Contribution to journal › Article › peer-review
  43 Citations (Scopus)

• Tocilizumab in patients with adult-onset still's disease refractory to glucocorticoid treatment: A randomised, double-blind, placebo-controlled phase III trial

  Kaneko, Y., Kameda, H., Ikeda, K., Ishii, T., Murakami, K., Takamatsu, H., Tanaka, Y., Abe, T. & Takeuchi, T., 2018 Dec 1, In: Annals of the rheumatic diseases. 77, 12, p. 1720-1729 10 p.

  Research output: Contribution to journal › Article › peer-review
  68 Citations (Scopus)

• Tocilizumab is clinically, functionally, and radiographically effective and safe either with or without low-dose methotrexate in active rheumatoid arthritis patients with inadequate responses to DMARDs and/or TNF inhibitors: A single-center retrospective cohort study (KEIO-TCZ study) at week 52

  Izumi, K., Kaneko, Y., Yasuoka, H., Seta, N., Kameda, H., Kuwana, M. & Takeuchi, T., 2015, In: Modern rheumatology. 25, 1, p. 31-37 7 p.

  Research output: Contribution to journal › Article › peer-review
  15 Citations (Scopus)

• Tocilizumab is effective against polymyalgia rheumatica: Experience in 13 intractable cases

  Izumi, K., Kuda, H., Ushikubo, M., Kuwana, M., Takeuchi, T. & Oshima, H., 2015 Jan, In: RMD Open. 1, 1, e000162.

  Research output: Contribution to journal › Article › peer-review
  20 Citations (Scopus)

• Tocilizumab monotherapy uncovered the role of the CCL22/17-CCR4⁺ Treg axis during remission of crescentic glomerulonephritis

  Sakai, R., Ito, M., Yoshimoto, K., Chikuma, S., Kurasawa, T., Kondo, T., Suzuki, K., Takeuchi, T., Amano, K. & Yoshimura, A., 2020, In: Clinical and Translational Immunology. 9, 11, e1203.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Citations (Scopus)

• Tofacitinib, an oral Janus kinase inhibitor, as monotherapy or with background methotrexate, in Japanese patients with rheumatoid arthritis: An open-label, long-term extension study

  Yamanaka, H., Tanaka, Y., Takeuchi, T., Sugiyama, N., Yuasa, H., Toyoizumi, S., Morishima, Y., Hirose, T. & Zwillich, S., 2016 Jan 28, In: Arthritis Research and Therapy. 18, 1, 34.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  90 Citations (Scopus)

• Tofacitinib in Combination With Methotrexate in Patients With Rheumatoid Arthritis: Clinical Efficacy, Radiographic, and Safety Outcomes From a Twenty-Four–Month, Phase III Study

  the ORAL Scan Investigators, 2019 Jun, In: Arthritis and Rheumatology. 71, 6, p. 878-891 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  43 Citations (Scopus)

• Tofacitinib in interstitial lung disease complicated with anti-MDA5 antibody-positive dermatomyositis: A literature review

  Takanashi, S., Kaneko, Y. & Takeuchi, T., 2021, (Accepted/In press) In: Modern rheumatology.

  Research output: Contribution to journal › Article › peer-review

• Tofogliflozin does not delay progression of carotid atherosclerosis in patients with type 2 diabetes: A prospective, randomized, open-label, parallel-group comparative study

  Katakami, N., Mita, T., Yoshii, H., Shiraiwa, T., Yasuda, T., Okada, Y., Torimoto, K., Umayahara, Y., Kaneto, H., Osonoi, T., Yamamoto, T., Kuribayashi, N., Maeda, K., Yokoyama, H., Kosugi, K., Ohtoshi, K., Hayashi, I., Sumitani, S., Tsugawa, M., Ryomoto, K., & 6 othersTaki, H., Nakamura, T., Kawashima, S., Sato, Y., Watada, H. & Shimomura, I., 2020 Jul 9, In: Cardiovascular Diabetology. 19, 1, 110.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  10 Citations (Scopus)

• TOF-SIMS imaging of halide/thiocyanate anions and hydrogen sulfide in mouse kidney sections using silver-deposited plates

  Akahoshi, N., Ishizaki, I., Naya, M., Maekawa, T., Yamazoe, S., Horiuchi, T., Kajimura, M., Ohashi, Y., Suematsu, M. & Ishii, I., 2012 Feb, In: Analytical and bioanalytical chemistry. 402, 5, p. 1859-1864 6 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• To go or not to go: The "itchy" effect on the destiny of hematopoietic stem cells

  Aki, D. & Liu, Y. C., 2011 Aug, In: Cell Research. 21, 8, p. 1161-1163 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• To impart automation technology to the next Genera

  Arai, T., Honda, S. & Kondo, K., 2005, In: Seimitsu Kogaku Kaishi/Journal of the Japan Society for Precision Engineering. 71, 10, p. 1193-1196 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access