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• Article

  Trypsin is a multifunctional factor in spermatogenesis

  Miura, C., Ohta, T., Ozaki, Y., Tanaka, H. & Miura, T., 2009 Dec 8, In: Proceedings of the National Academy of Sciences of the United States of America. 106, 49, p. 20972-20977 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  25 Citations (Scopus)

• Tryptase increases proliferative activity of human conjunctival fibroblasts through protease-activated receptor-2

  Asano-Kato, N., Fukagawa, K., Okada, N., Dogru, M., Tsubota, K. & Fujishima, H., 2005 Dec, In: Investigative Ophthalmology and Visual Science. 46, 12, p. 4622-4626 5 p.

  Research output: Contribution to journal › Article › peer-review
  21 Citations (Scopus)

• Tryptophan Inhibits the [³H]Glutamate Uptake into Xenopus Oocytes Injected with Rat Brain mRNA

  Tohda, M., Urushihara, H. & Nomura, Y., 1992 Jan, In: The Japanese Journal of Pharmacology. 59, 4, p. 477-479 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Tryptophan Metabolism Regulates Proliferative Capacity of Human Pluripotent Stem Cells

  Someya, S., Tohyama, S., Kameda, K., Tanosaki, S., Morita, Y., Sasaki, K., Kang, M. I., Kishino, Y., Okada, M., Tani, H., Soma, Y., Nakajima, K., Umei, T., Sekine, O., Moriwaki, T., Kanazawa, H., Kobayashi, E., Fujita, J. & Fukuda, K., 2021 Feb 19, In: iScience. 24, 2, 102090.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  9 Citations (Scopus)

• T-shaped GaAs quantum-wire lasers and the exciton Mott transition

  Yoshita, M., Liu, S. M., Okano, M., Hayamizu, Y., Akiyama, H., Pfeiffer, L. N. & West, K. W., 2007 Jul 25, In: Journal of Physics Condensed Matter. 19, 29, 295217.

  Research output: Contribution to journal › Article › peer-review
  13 Citations (Scopus)

• TSHR mutations as a cause of congenital hypothyroidism in Japan: A population-based genetic epidemiology study

  Narumi, S., Muroya, K., Abe, Y., Yasui, M., Asakura, Y., Adachi, M. & Hasegawa, T., 2009 Apr, In: Journal of Clinical Endocrinology and Metabolism. 94, 4, p. 1317-1323 7 p.

  Research output: Contribution to journal › Article › peer-review
  67 Citations (Scopus)

• TSPAN2 Is Involved in Cell Invasion and Motility during Lung Cancer Progression

  Otsubo, C., Otomo, R., Miyazaki, M., Matsushima-Hibiya, Y., Kohno, T., Iwakawa, R., Takeshita, F., Okayama, H., Ichikawa, H., Saya, H., Kiyono, T., Ochiya, T., Tashiro, F., Nakagama, H., Yokota, J. & Enari, M., 2014 Apr 24, In: Cell Reports. 7, 2, p. 527-538 12 p.

  Research output: Contribution to journal › Article › peer-review
  27 Citations (Scopus)

• TSR Quantum Dots and their Application to Nanometer-size Memory Devices

  Sakuma, Y., Awano, Y. & Shima, M., 1998, In: Fujitsu Scientific and Technical Journal. 34, 2, p. 162-181 20 p.

  Research output: Contribution to journal › Article › peer-review

• TSU-68 (SU6668) inhibits local tumor growth and liver metastasis of human colon cancer xenografts via anti-angiogenesis

  Yorozuya, K., Kubota, T., Watanabe, M., Hasegawa, H., Ozawa, S., Kitajima, M., Chikahisa, L. M. & Yamada, Y., 2005 Sep 1, In: Oncology reports. 14, 3, p. 677-682 6 p.

  Research output: Contribution to journal › Article › peer-review
  22 Citations (Scopus)

• Tsunami height poles and disaster awareness: Memory, education and awareness of disaster on the reconstruction for resilient city in Banda Aceh, Indonesia

  Sugimoto, M., Iemura, H. & Shaw, R., 2010 Nov 9, In: Disaster Prevention and Management: An International Journal. 19, 5, p. 527-540 14 p.

  Research output: Contribution to journal › Article › peer-review
  17 Citations (Scopus)

• T-type calcium channel blockade as a therapeutic strategy against renal injury in rats with subtotal nephrectomy

  Sugano, N., Wakino, S., Kanda, T., Tatematsu, S., Homma, K., Yoshioka, K., Hasegawa, K., Hara, Y., Suetsugu, Y., Yoshizawa, T., Hara, Y., Utsunomiya, Y., Tokudome, G., Hosoya, T., Saruta, T. & Hayashi, K., 2008 Apr, In: Kidney international. 73, 7, p. 826-834 9 p.

  Research output: Contribution to journal › Article › peer-review
  43 Citations (Scopus)

• T-type Calcium Channels Determine the Vulnerability of Dopaminergic Neurons to Mitochondrial Stress in Familial Parkinson Disease

  Tabata, Y., Imaizumi, Y., Sugawara, M., Andoh-Noda, T., Banno, S., Chai, M. C., Sone, T., Yamazaki, K., Ito, M., Tsukahara, K., Saya, H., Hattori, N., Kohyama, J. & Okano, H., 2018 Nov 13, In: Stem cell reports. 11, 5, p. 1171-1184 14 p.

  Research output: Contribution to journal › Article › peer-review
  50 Citations (Scopus)

• TUBA1A mutation can cause a hydranencephaly-like severe form of cortical dysgenesis

  Yokoi, S., Ishihara, N., Miya, F., Tsutsumi, M., Yanagihara, I., Fujita, N., Yamamoto, H., Kato, M., Okamoto, N., Tsunoda, T., Yamasaki, M., Kanemura, Y., Kosaki, K., Kojima, S., Saitoh, S., Kurahashi, H. & Natsume, J., 2015 Oct 23, In: Scientific reports. 5, 15165.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  17 Citations (Scopus)

• Tuberculoma mimicking falx meningioma: Case report

  Adachi, K., Yoshida, K., Tomita, H., Niimi, M. & Kawase, T., 2004 Sep, In: Neurologia medico-chirurgica. 44, 9, p. 489-492 4 p.

  Research output: Contribution to journal › Article › peer-review
  12 Citations (Scopus)

• Tuberculous meningitis in Japanese children between 1980-1991

  Kazushige, I., Mituko, S., Kazuteru, K., Hiroshi, K. & Chuichi, K., 1993 Apr, In: kekkaku(tuberculosis). 67, 9, p. 607-612 6 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Tuberculous spondylitis

  Fukuda, K., Shioda, M., Takemitsu, M., Kaneko, S., Yagi, M., Fujiyoshi, K., Iizuka, S., Nagoshi, N., Hasegawa, A., Machida, M. & Usui, H., 2012 Mar 1, In: IRYO - Japanese Journal of National Medical Services. 66, 3, p. 114-119 6 p.

  Research output: Contribution to journal › Article › peer-review

• Tuberous sclerosis diagnosed by incidental computed tomography findings of multifocal micronodular pneumocyte hyperplasia: A case report

  Ishii, M., Asano, K., Kamiishi, N., Hayashi, Y., Arai, D., Haraguchi, M., Sugiura, H., Naoki, K., Tasaka, S., Soejima, K., Sayama, K. & Betsuyaku, T., 2012, In: Journal of Medical Case Reports. 6, 352.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Tubiferic acid, a new 9,10-secocycloartane triterpenoid acid isolated from the myxomycete Tubulifera arachnoidea

  Ippongi, Y., Ohtsuki, T., Toume, K., Arai, M. A., Yamamoto, Y. & Ishibashi, M., 2011 Feb, In: Chemical and Pharmaceutical Bulletin. 59, 2, p. 279-281 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  6 Citations (Scopus)

• Tubular dysfunction in extremely low birth weight survivors

  Matsumura, K., Matsuzaki, Y., Hida, M., Ikeda, K. & Awazu, M., 2019 Mar 15, In: Clinical and experimental nephrology. 23, 3, p. 395-401 7 p.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• Tubular Dysfunction Mimicking Dent's Disease in 2 Infants Born with Extremely Low Birth Weight

  Awazu, M., Arai, M., Ohashi, S., Takahashi, H., Sekine, T. & Ikeda, K., 2017 Jan 6, In: Case Reports in Nephrology and Dialysis. 7, 1, p. 13-17 5 p.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Tubular hydroxyapatite formation through a hydrothermal process from α-tricalcium phosphate with anatase

  Kamitakahara, M., Takahashi, H. & Ioku, K., 2012 May, In: Journal of Materials Science. 47, 9, p. 4194-4199 6 p.

  Research output: Contribution to journal › Article › peer-review
  11 Citations (Scopus)

• Tubulointerstitial nephritis and uveitis syndrome: A case with an autoimmune reactivity against retinal and renal antigens

  Shimazaki, K., Jirawuthiworavong, G. V., Nguyen, E. V., Awazu, M., Levinson, R. D. & Gordon, L. K., 2008 Jan, In: Ocular Immunology and Inflammation. 16, 1-2, p. 51-53 3 p.

  Research output: Contribution to journal › Article › peer-review
  19 Citations (Scopus)

• Tubulointerstitial nephritis and uveitis syndrome with autoantibody directed to renal tubular cells

  Wakaki, H., Sakamoto, H. & Awazu, M., 2001, In: Pediatrics. 107, 6, p. 1443-1446 4 p.

  Research output: Contribution to journal › Article › peer-review
  47 Citations (Scopus)

• Tubulointerstitial nephritis antigen-like 1 is expressed in extraembryonic tissues and interacts with laminin 1 in the Reichert membrane at postimplantation in the mouse

  Igarashi, T., Tajiri, Y., Sakurai, M., Sato, E., Li, D., Mukai, K., Suematsu, M., Fukui, E., Yoshizawa, M. & Matsumoto, H., 2009, In: Biology of reproduction. 81, 5, p. 948-955 8 p.

  Research output: Contribution to journal › Article › peer-review
  21 Citations (Scopus)

• Tubulointerstitial nephritis antigen-like 1 is expressed in the uterus and binds with integrins in decidualized endometrium during postimplantation in mice.

  Tajiri, Y., Igarashi, T., Li, D., Mukai, K., Suematsu, M., Fukui, E., Yoshizawa, M. & Matsumoto, H., 2010 Feb, In: Biology of reproduction. 82, 2, p. 263-270 8 p.

  Research output: Contribution to journal › Article › peer-review
  23 Citations (Scopus)

• Tudor-domain containing proteins act to make the piRNA pathways more robust in Drosophila

  Sato, K., Iwasaki, Y. W., Siomi, H. & Siomi, M. C., 2015 Jan 1, In: Fly. 9, 2, p. 86-90 5 p.

  Research output: Contribution to journal › Article › peer-review
  8 Citations (Scopus)

• Tug-of-war model for the two-bandit problem: Nonlocally-correlated parallel exploration via resource conservation

  Kim, S. J., Aono, M. & Hara, M., 2010 Jul 1, In: BioSystems. 101, 1, p. 29-36 8 p.

  Research output: Contribution to journal › Article › peer-review
  53 Citations (Scopus)

• Tumor and Tumor-Associated Macrophage Programmed Death-Ligand 1 Expression Is Associated With Adjuvant Chemotherapy Benefit in Lung Adenocarcinoma

  Gross, D. J., Chintala, N. K., Vaghjiani, R. G., Grosser, R., Tan, K. S., Li, X., Choe, J., Li, Y., Aly, R. G., Emoto, K., Zheng, H., Dux, J., Cheema, W., Bott, M. J., Travis, W. D., Isbell, J. M., Li, B. T., Jones, D. R. & Adusumilli, P. S., 2022 Jan, In: Journal of Thoracic Oncology. 17, 1, p. 89-102 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  5 Citations (Scopus)

• Tumor angiogenesis and dynamic CT in lung adenocarcinoma: Radiologic-Pathologic correlation

  Tateishi, U., Nishihara, H., Watanabe, S., Morikawa, T., Abe, K. & Miyasaka, K., 2001, In: Journal of Computer Assisted Tomography. 25, 1, p. 23-27 5 p.

  Research output: Contribution to journal › Article › peer-review
  102 Citations (Scopus)

• Tumor angiogenesis in the bone marrow of multiple myeloma patients and its alterations by thalidomide treatment

  Du, W., Hattori, Y., Hashiguchi, A., Kondoh, K., Hozumi, N., Ikeda, Y., Sakamoto, M., Hata, J. I. & Yamada, T., 2004 May 1, In: Pathology international. 54, 5, p. 285-294 10 p.

  Research output: Contribution to journal › Article › peer-review
  40 Citations (Scopus)

• Tumor antigens isolated from a patient with vitiligo and T-cell-infiltrated melanoma

  Kiniwa, Y., Fujita, T., Akada, M., Ito, K., Shofuda, T., Suzuki, Y., Yamamoto, A., Saida, T. & Kawakami, Y., 2001 Nov 1, In: Cancer Research. 61, 21, p. 7900-7907 8 p.

  Research output: Contribution to journal › Article › peer-review
  38 Citations (Scopus)

• Tumor associated macrophages support the growth of FGF9-induced lung adenocarcinoma by multiple mechanisms

  Hegab, A. E., Ozaki, M., Kagawa, S., Hamamoto, J., Yasuda, H., Naoki, K., Soejima, K., Yin, Y., Kinoshita, T., Yaguchi, T., Kawakami, Y., Ornitz, D. M. & Betsuyaku, T., 2018 May, In: Lung Cancer. 119, p. 25-35 11 p.

  Research output: Contribution to journal › Article › peer-review
  18 Citations (Scopus)

• Tumor budding, a novel prognostic indicator for predicting stage progression in T1 bladder cancers

  Fukumoto, K., Kikuchi, E., Mikami, S., Ogihara, K., Matsumoto, K., Miyajima, A. & Oya, M., 2016 Sep 1, In: Cancer science. 107, 9, p. 1338-1344 7 p.

  Research output: Contribution to journal › Article › peer-review
  30 Citations (Scopus)

• Tumor budding and human chorionic gonadotropin-β expression correlate with unfavorable patient outcome in colorectal carcinoma

  Konishi, Y., Kawamata, F., Nishihara, H., Homma, S., Kato, Y., Tsuda, M., Kohsaka, S., Einama, T., Liu, C., Yoshida, T., Nagatsu, A., Tanino, M., Tanaka, S., Kawamura, H., Kamiyama, T. & Taketomi, A., 2018 Jul 1, In: Medical Oncology. 35, 7, 104.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• Tumor Burden Score and Serum Alpha-fetoprotein Subclassify Intermediate-Stage Hepatocellular Carcinoma

  Lima, H. A., Endo, Y., Alaimo, L., Moazzam, Z., Munir, M. M., Shaikh, C., Resende, V., Guglielmi, A., Marques, H. P., Cauchy, F., Lam, V., Poultsides, G. A., Popescu, I., Alexandrescu, S., Martel, G., Hugh, T., Endo, I., Kitago, M., Shen, F. & Pawlik, T. M., 2022 Dec, In: Journal of Gastrointestinal Surgery. 26, 12, p. 2512-2521 10 p.

  Research output: Contribution to journal › Article › peer-review

• Tumor cell-derived angiopoietin-like protein ANGPTL2 is a critical driver of metastasis

  Endo, M., Nakano, M., Kadomatsu, T., Fukuhara, S., Kuroda, H., Mikami, S., Hato, T., Aoi, J., Horiguchi, H., Miyata, K., Odagiri, H., Masuda, T., Harada, M., Horio, H., Hishima, T., Nomori, H., Ito, T., Yamamoto, Y., Minami, T., Okada, S., & 4 othersTakahashi, T., Mochizuki, N., Iwase, H. & Oike, Y., 2012 Apr 1, In: Cancer Research. 72, 7, p. 1784-1794 11 p.

  Research output: Contribution to journal › Article › peer-review
  97 Citations (Scopus)

• Tumor cell dynamics and metastasis in advanced neuroblastoma

  Kuroda, T., Honna, T., Morikawa, N., Kitano, Y., Fuchimoto, Y., Terawaki, K., Kumagai, M., Tsunematsu, Y., Masaki, H., Matsuoka, K. & Saeki, M., 2005 Nov 1, In: Pediatric surgery international. 21, 11, p. 859-863 5 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• Tumor cell-matrix interaction: pericellular matrix degradation and metastasis.

  Okada, Y., 2000, In: Verhandlungen der Deutschen Gesellschaft für Pathologie. 84, p. 33-42 10 p.

  Research output: Contribution to journal › Article › peer-review
  28 Citations (Scopus)

• Tumor depth as a predictor of lymph node metastasis of supraglottic and hypopharyngeal cancers

  Tomifuji, M., Imanishi, Y., Araki, K., Yamashita, T., Yamamoto, S., Kameyama, K. & Shiotani, A., 2011 Feb, In: Annals of Surgical Oncology. 18, 2, p. 490-496 7 p.

  Research output: Contribution to journal › Article › peer-review
  41 Citations (Scopus)

• Tumor expression of calcium sensing receptor and colorectal cancer survival: Results from the nurses’ health study and health professionals follow-up study

  Momen-Heravi, F., Masugi, Y., Qian, Z. R., Nishihara, R., Liu, L., Smith-Warner, S. A., Keum, N. N., Zhang, L., Tchrakian, N., Nowak, J. A., Yang, W., Ma, Y., Bowden, M., da Silva, A., Wang, M., Fuchs, C. S., Meyerhardt, J. A., Ng, K., Wu, K., Giovannucci, E., & 2 othersOgino, S. & Zhang, X., 2017 Dec 15, In: International Journal of Cancer. 141, 12, p. 2471-2479 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  8 Citations (Scopus)

• Tumor growth and metastasis of human colorectal cancer cell lines in SCID mice resemble clinical metastatic behaviors

  Yasui, N., Sakamoto, M., Ochiai, A., Ino, Y., Akimoto, S., Orikasa, A., Kitajima, M. & Hirohashi, S., 1997, In: Invasion and Metastasis. 17, 5, p. 259-269 11 p.

  Research output: Contribution to journal › Article › peer-review
  18 Citations (Scopus)

• Tumor growth inhibition by intratumoral inoculation of defective herpes simplex virus vectors expressing granulocyte - Macrophage colony-stimulating factor

  Toda, M., Martuza, R. L. & Rabkin, S. D., 2000 Oct, In: Molecular Therapy. 2, 4, p. 324-329 6 p.

  Research output: Contribution to journal › Article › peer-review
  98 Citations (Scopus)

• Tumor immune microenvironment is associated with the growth of intracranial germinomas

  Nishimoto, M., Ohara, K., Kamamoto, D., Tamura, R., Miwa, T., Yoshida, K. & Sasaki, H., 2020 Jan 1, In: Journal of Neuro-Oncology. 146, 1, p. 139-146 8 p.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• Tumor imprint cytology of ovarian ependymoma: A case report

  Komuro, Y., Mikami, M., Sakaiya, N., Kurahashi, T., Komiyama, S., Tei, C., Mukai, M. & Hirose, T., 2001 Dec 15, In: Cancer. 92, 12, p. 3165-3169 5 p.

  Research output: Contribution to journal › Article › peer-review
  15 Citations (Scopus)

• Tumor-infiltrating lymphocytes predict survival outcomes in patients with cervical cancer treated with concurrent chemoradiotherapy

  Ohno, A., Iwata, T., Katoh, Y., Taniguchi, S., Tanaka, K., Nishio, H., Nakamura, M., Morisada, T., Chen, G., Saito, M., Yaguchi, T., Kawakami, Y. & Aoki, D., 2020 Nov, In: Gynecologic Oncology. 159, 2, p. 329-334 6 p.

  Research output: Contribution to journal › Article › peer-review
  12 Citations (Scopus)

• Tumor initiating potential of side population cells in human gastric cancer

  Fukuda, K., Saikawa, Y., Ohashi, M., Kumagai, K., Kitajima, M., Okano, H., Matsuzaki, Y. & Kitagawa, Y., 2009, In: International journal of oncology. 34, 5, p. 1201-1207 7 p.

  Research output: Contribution to journal › Article › peer-review
  119 Citations (Scopus)

• Tumor innate immunity primed by specific interferon-stimulated endogenous retroviruses

  Cañadas, I., Thummalapalli, R., Kim, J. W., Kitajima, S., Jenkins, R. W., Christensen, C. L., Campisi, M., Kuang, Y., Zhang, Y., Gjini, E., Zhang, G., Tian, T., Sen, D. R., Miao, D., Imamura, Y., Thai, T., Piel, B., Terai, H., Aref, A. R., Hagan, T., & 18 othersKoyama, S., Watanabe, M., Baba, H., Adeni, A. E., Lydon, C. A., Tamayo, P., Wei, Z., Herlyn, M., Barbie, T. U., Uppaluri, R., Sholl, L. M., Sicinska, E., Sands, J., Rodig, S., Wong, K. K., Paweletz, C. P., Watanabe, H. & Barbie, D. A., 2018 Aug 1, In: Nature medicine. 24, 8, p. 1143-1150 8 p.

  Research output: Contribution to journal › Article › peer-review
  156 Citations (Scopus)

• Tumor invasion of extralobar soft tissue beyond the hilar region does not affect the prognosis of surgically resected lung cancer patients

  Otsuka, H., Ishii, G., Yoshida, J., Yamaguchi, Y., Hishida, T., Nishimura, M., Nagai, K. & Ochiai, A., 2010 Oct, In: Journal of Thoracic Oncology. 5, 10, p. 1571-1575 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Tumor LINE-1 methylation level and colorectal cancer location in relation to patient survival

  Mima, K., Nowak, J. A., Qian, Z. R., Cao, Y., Song, M., Masugi, Y., Shi, Y., da Silva, A., Gu, M., Li, W., Hamada, T., Zhang, X., Wu, K., Meyerhardt, J. A., Baba, H., Giovannucci, E. L., Chan, A. T., Fuchs, C. S., Ogino, S. & Nishihara, R., 2016, In: Oncotarget. 7, 34, p. 55098-55109 12 p.

  Research output: Contribution to journal › Article › peer-review
  28 Citations (Scopus)

• Tumor LINE-1 methylation level and microsatellite instability in relation to colorectal cancer prognosis

  Inamura, K., Yamauchi, M., Nishihara, R., Lochhead, P., Qian, Z. R., Kuchiba, A., Kim, S. A., Mima, K., Sukawa, Y., Jung, S., Zhang, X., Wu, K., Cho, E., Chan, A. T., Meyerhardt, J. A., Harris, C. C., Fuchs, C. S. & Ogino, S., 2014 Sep 1, In: Journal of the National Cancer Institute. 106, 9

  Research output: Contribution to journal › Article › peer-review
  55 Citations (Scopus)