Find Research outputs

Search results

• Therapeutic effect of lecithinized superoxide dismutase Against colitis

  Ishihara, T., Tanaka, K. I., Tasaka, Y., Namba, T., Suzuki, J., Ishihara, T., Okamoto, S., Hibi, T., Takenaga, M., Igarashi, R., Sato, K., Mizushima, Y. & Mizushima, T., 2009 Jan 1, In: Journal of Pharmacology and Experimental Therapeutics. 328, 1, p. 152-164 13 p.

  Research output: Contribution to journal › Article › peer-review
  82 Citations (Scopus)

• Therapeutic effect of lecithinized superoxide dismutase on bleomycin-induced pulmonary fibrosis

  Tanaka, K. I., Ishihara, T., Azuma, A., Kudoh, S., Ebina, M., Nukiwa, T., Sugiyama, Y., Tasaka, Y., Namba, T., Ishihara, T., Sato, K., Mizushima, Y. & Mizushima, T., 2010 Mar, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 298, 3, p. L348-L360

  Research output: Contribution to journal › Article › peer-review
  61 Citations (Scopus)

• Therapeutic effect of lecithinized superoxide dismutase on pulmonary emphysema

  Tanaka, K. I., Tanaka, Y., Miyazaki, Y., Namba, T., Sato, K., Aoshiba, K., Azuma, A. & Mizushima, T., 2011 Sep, In: Journal of Pharmacology and Experimental Therapeutics. 338, 3, p. 810-818 9 p.

  Research output: Contribution to journal › Article › peer-review
  26 Citations (Scopus)

• Therapeutic effect of prenatal alkalization and PTC124 in Na + /HCO 3 - Cotransporter 1 p.W516∗ knock-in mice

  Fang, Y. W., Yang, S. S., Chau, T., Nakamura, M., Yamazaki, O., Seki, G., Yamada, H., Hsu, H. M., Cheng, C. J. & Lin, S. H., 2015 May 9, In: Gene Therapy. 22, 5, p. 374-381 8 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• Therapeutic effect of RAS inhibitors on epigenetic changes in life-style related diseases

  Hayashi, K. & Itoh, H., 2015 Nov 1, In: Nihon rinsho. Japanese journal of clinical medicine. 73, 11, p. 1933-1938 6 p.

  Research output: Contribution to journal › Article › peer-review

• Therapeutic effect of vitamin D₃-containing nanostructured lipid carriers on inflammatory bowel disease

  Zai, K., Hirota, M., Yamada, T., Ishihara, N., Mori, T., Kishimura, A., Suzuki, K., Hase, K. & Katayama, Y., 2018 Sep 28, In: Journal of Controlled Release. 286, p. 94-102 9 p.

  Research output: Contribution to journal › Article › peer-review
  16 Citations (Scopus)

• Therapeutic effects of flurbiprofen axetil on mesenteric traction syndrome: randomized clinical trial

  Takahashi, H., Shida, D., Tagawa, K., Iwamoto, R., Arita, M., Arai, H. & Suzuki, T., 2017 Aug 11, In: BMC surgery. 17, 1, p. 90 1 p., 90.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  6 Citations (Scopus)

• Therapeutic effects of gyokuheifusan on NC/Nga mouse model of allergic dermatitis

  Nakatsukasa, H., Tago, F., Okamoto, T., Tsukimoto, M. & Kojima, S., 2009 Aug, In: Journal of Health Science. 55, 4, p. 516-524 9 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Therapeutic effects of the combination of methotrexate and bucillamine in early rheumatoid arthritis: A multicenter, double-blind, randomized controlled study

  Ichikawa, Y., Saito, T., Yamanaka, H., Akizuki, M., Kondo, H., Kobayashi, S., Oshima, H., Kawai, S., Hama, N., Yamada, H., Mimori, T., Amano, K., Tanaka, Y., Matsuoka, Y., Yamamoto, S., Matsubara, T., Murata, N., Asai, T., Suzuki, Y., Okano, Y., & 15 othersAkaboshi, T., Fujii, T., Hirakata, M., Suzuki, T., Takubo, N., Miyata, Y., Sato, Y., Nishimoto, N., Saito, E., Sawada, S., Rikimaru, A., Yamagata, H., Toma, S., Ito, K. & Yoshida, K., 2005 Oct, In: Modern rheumatology. 15, 5, p. 323-328 6 p.

  Research output: Contribution to journal › Article › peer-review
  38 Citations (Scopus)

• Therapeutic effects of various initial combinations of chemotherapy including clarithromycin against Mycobacterium avium complex pulmonary disease

  Hasegawa, N., Nishimura, T., Ohtani, S., Takeshita, K., Fukunaga, K., Tasaka, S., Urano, T., Ishii, K., Miyairi, M. & Ishizaka, A., 2009 Dec 1, In: Chest. 136, 6, p. 1569-1575 7 p.

  Research output: Contribution to journal › Article › peer-review
  35 Citations (Scopus)

• Therapeutic efficacy after percutaneous transluminal pulmonary angioplasty in CTEPH with and without clotting disorder according to anti-cardiolipin antibody

  Sueoka, J., Kataoka, M., Shimura, N., Inami, T., Yanagisawa, R., Ishiguro, H., Kawakami, T., Fukuda, K., Yoshino, H. & Satoh, T., 2015 Oct 10, In: International Journal of Cardiology. 201, p. 271-273 3 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Therapeutic enhancement of S-1 with CPT-11 through down-regulation of thymidylate synthase in bladder cancer

  Ide, H., Kikuchi, E., Hasegawa, M., Hattori, S., Yasumizu, Y., Miyajima, A. & Oya, M., 2013 Aug, In: Cancer medicine. 2, 4, p. 488-495 8 p.

  Research output: Contribution to journal › Article › peer-review
  7 Citations (Scopus)

• Therapeutic hypothermia achieves neuroprotection via a decrease in acetylcholine with a concurrent increase in carnitine in the neonatal hypoxia-ischemia

  Takenouchi, T., Sugiura, Y., Morikawa, T., Nakanishi, T., Nagahata, Y., Sugioka, T., Honda, K., Kubo, A., Hishiki, T., Matsuura, T., Hoshino, T., Takahashi, T., Suematsu, M. & Kajimura, M., 2015 May 5, In: Journal of Cerebral Blood Flow and Metabolism. 35, 5, p. 794-805 12 p.

  Research output: Contribution to journal › Article › peer-review
  22 Citations (Scopus)

• Therapeutic hypothermia for neonatal encephalopathy: JSPNM & MHLW Japan Working Group Practice Guidelines. Consensus Statement from the Working Group on Therapeutic Hypothermia for Neonatal Encephalopathy, Ministry of Health, Labor and Welfare (MHLW), Japan, and Japan Society for Perinatal and Neonatal Medicine (JSPNM)

  Takenouchi, T., Iwata, O., Nabetani, M. & Tamura, M., 2012 Feb, In: Brain and Development. 34, 2, p. 165-170 6 p.

  Research output: Contribution to journal › Comment/debate › peer-review
  39 Citations (Scopus)

• Therapeutic hypothermia for neonatal encephalopathy: A report from the first 3 years of the Baby Cooling Registry of Japan

  Tsuda, K., Mukai, T., Iwata, S., Shibasaki, J., Tokuhisa, T., Ioroi, T., Sano, H., Yutaka, N., Takahashi, A., Takeuchi, A., Takenouchi, T., Araki, Y., Sobajima, H., Tamura, M., Hosono, S., Nabetani, M. & Iwata, O., 2017 Jan 4, In: Scientific reports. 7, 39508.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  19 Citations (Scopus)

• Therapeutic hypothermia for out-of-hospital cardiac arrest: An update for neurosurgeons

  Inamasu, J., Nakatsukasa, M., Suzuki, M. & Miyatake, S., 2010 Jul, In: World neurosurgery. 74, 1, p. 120-128 9 p.

  Research output: Contribution to journal › Review article › peer-review
  4 Citations (Scopus)

• Therapeutic hypothermia for severely head-injured patients with acute subdural haematoma

  Inamasu, J., Saito, R., Nakamura, Y., Horiguchi, T., Kuroshima, Y. & Ichikizaki, K., 2006 Aug, In: Journal of Clinical Neuroscience. 13, 7, p. 733-737 5 p.

  Research output: Contribution to journal › Article › peer-review
  7 Citations (Scopus)

• Therapeutic impact of dietary vitamin D supplementation for preventing right ventricular remodeling and improving survival in pulmonary hypertension

  Tanaka, H., Kataoka, M., Isobe, S., Yamamoto, T., Shirakawa, K., Endo, J., Satoh, T., Hakamata, Y., Kobayashi, E., Sano, M. & Fukuda, K., 2017 Jul, In: PloS one. 12, 7, e0180615.

  Research output: Contribution to journal › Article › peer-review
  23 Citations (Scopus)

• Therapeutic impact of erythropoietin-encapsulated liposomes targeted to bone marrow on renal anemia

  Miyazaki, Y., Taguchi, K., Sou, K., Watanabe, H., Ishima, Y., Miyakawa, T., Mitsuya, H., Fukagawa, M., Otagiri, M. & Maruyama, T., 2014 Sep 25, In: Molecular Pharmaceutics. 11, 11, p. 4238-4248 11 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• Therapeutic impact of human serum albumin-thioredoxin fusion protein on influenza virus-induced lung injury mice

  Tanaka, R., Ishima, Y., Enoki, Y., Kimachi, K., Shirai, T., Watanabe, H., Chuang, V. T. G., Maruyama, T. & Otagiri, M., 2014, In: Frontiers in Immunology. 5, NOV, 561.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  22 Citations (Scopus)

• Therapeutic implications of cortical spreading depression models in migraine

  Takizawa, T., Ayata, C. & Chen, S. P., 2020, Update on Emerging Treatments for Migraine. Wang, S-J., Wang, S-J., Lau, C. I., Lau, C. I., Lau, C. I., Lau, C. I. & Lau, C. I. (eds.). Elsevier B.V., p. 29-67 39 p. (Progress in Brain Research; vol. 255).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  6 Citations (Scopus)

• Therapeutic monoclonal antibodies

  Yamada, T., 2011 Jun, In: Keio Journal of Medicine. 60, 2, p. 37-46 10 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  42 Citations (Scopus)

• Therapeutic pars plana vitrectomy for chronic uveitis

  Ozawa, Y., Suzuki, S., Ishida, S., Shinoda, K. & Katsura, H., 1999 Dec 1, In: Folia Ophthalmologica Japonica. 50, 12, p. 933-937 5 p.

  Research output: Contribution to journal › Article › peer-review

• Therapeutic potential of appropriately evaluated safe-induced pluripotent stem cells for spinal cord injury

  Tsuji, O., Miura, K., Okada, Y., Fujiyoshi, K., Mukaino, M., Nagoshi, N., Kitamura, K., Kumagai, G., Nishino, M., Tomisato, S., Higashi, H., Nagai, T., Katoh, H., Kohda, K., Matsuzaki, Y., Yuzaki, M., Ikeda, E., Toyama, Y., Nakamura, M., Yamanaka, S., & 1 othersOkano, H., 2010 Jul 13, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 28, p. 12704-12709 6 p.

  Research output: Contribution to journal › Article › peer-review
  422 Citations (Scopus)

• Therapeutic potential of a reduced-intensity preparative regimen for allogeneic transplantation with cladribine, busulfan, and antithymocyte globulin against advanced/refractory acute leukemia/lymphoma

  Saito, T., Kanda, Y., Kami, M., Kato, K., Shoji, N., Kanai, S., Ohnishi, T., Kawano, Y., Nakai, K., Ogasawara, T., Matsubara, H., Makimoto, A., Tanosaki, R., Tobinai, K., Wakasugi, H., Takaue, Y. & Mineishi, S., 2002 Apr 1, In: Clinical Cancer Research. 8, 4, p. 1014-1020 7 p.

  Research output: Contribution to journal › Article › peer-review
  49 Citations (Scopus)

• Therapeutic potential of atrial natriuretic peptide administration on peripheral arterial diseases

  Park, K., Itoh, H., Yamahara, K., Sone, M., Miyashita, K., Oyamada, N., Sawada, N., Taura, D., Inuzuka, M., Sonoyama, T., Tsujimoto, H., Fukunaga, Y., Tamura, N. & Nakao, K., 2008 Feb, In: Endocrinology. 149, 2, p. 483-491 9 p.

  Research output: Contribution to journal › Article › peer-review
  25 Citations (Scopus)

• Therapeutic potential of induced pluripotent stem cells for spinal cord injury

  Nori, S., Tsuji, O., Okada, Y., Toyama, Y., Okano, H. & Nakamura, M., 2012 Jan 1, In: Brain and Nerve. 64, 1, p. 17-27 11 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• Therapeutic potential of recombinant thrombomodulin for lung injury after pneumonectomy via inhibition of high-mobility group box 1 in mice

  Takahashi, Y., Matsutani, N., Dejima, H., Nakayama, T., Okamura, R., Uehara, H. & Kawamura, M., 2016 Nov 1, In: Journal of Trauma and Acute Care Surgery. 81, 5, p. 868-875 8 p.

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)

• Therapeutic potential of thiazolidinediones in activation of peroxisome proliferator-activated receptor γ for monocyte recruitment and endothelial regeneration

  Tanaka, T., Fukunaga, Y., Itoh, H., Doi, K., Yamashita, J., Chun, T. H., Inoue, M., Masatsugu, K., Saito, T., Sawada, N., Sakaguchi, S., Arai, H. & Nakao, K., 2005 Jan 31, In: European journal of pharmacology. 508, 1-3, p. 255-265 11 p.

  Research output: Contribution to journal › Article › peer-review
  42 Citations (Scopus)

• Therapeutic potential of tranilast for the treatment of chronic graft-versus-host disease in mice

  Mukai, S., Ogawa, Y., Saya, H., Kawakami, Y. & Tsubota, K., 2018 Oct, In: PloS one. 13, 10, e0203742.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  7 Citations (Scopus)

• Therapeutic potential of transgenic mesenchymal stem cells engineered to mediate anti-high mobility group box 1 activity: Targeting of colon cancer

  Kikuchi, H., Yagi, H., Hasegawa, H., Ishii, Y., Okabayashi, K., Tsuruta, M., Hoshino, G., Takayanagi, A. & Kitagawa, Y., 2014 Jul, In: Journal of Surgical Research. 190, 1, p. 134-143 10 p.

  Research output: Contribution to journal › Article › peer-review
  22 Citations (Scopus)

• Therapeutic potentials of unicellular green alga Chlorella in advanced glycation end product (AGE)-related disorders

  Yamagishi, S., Nakamura, K. & Inoue, H., 2005, In: Medical Hypotheses. 65, 5, p. 953-955 3 p.

  Research output: Contribution to journal › Article › peer-review
  20 Citations (Scopus)

• Therapeutic results for 100 patients with cancer of the mobile tongue treated with low dose rate interstitial irradiation

  Kobayashi, Y., Karasawa, K., Komiya, Y., Hanyu, N., Okamoto, M., Chang, T. C., Kiguchi, Y., Uchida, I., Yoshida, S. & Asoda, S., 2007 May, In: Anticancer research. 27, 3 B, p. 1689-1692 4 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Therapeutic role of miR-19a/19b in cardiac regeneration and protection from myocardial infarction

  Gao, F., Kataoka, M., Liu, N., Liang, T., Huang, Z. P., Gu, F., Ding, J., Liu, J., Zhang, F., Ma, Q., Wang, Y., Zhang, M., Hu, X., Kyselovic, J., Hu, X., Pu, W. T., Wang, J., Chen, J. & Wang, D. Z., 2019 Dec 1, In: Nature communications. 10, 1, 1802.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  133 Citations (Scopus)

• Therapeutic strategies for advanced respectable esophageal cancer

  Kitagawa, Y., 2008 Nov, In: Nippon Geka Gakkai zasshi. 109, 6, p. 333-337 5 p.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• Therapeutic strategies for atopic dermatitis on skin barrier function

  Ebihara, T., 2014 Jan 1, In: Japanese Journal of Allergology. 63, 6, p. 758-763 6 p.

  Research output: Contribution to journal › Article › peer-review

• Therapeutic strategies for functional dyspepsia and the introduction of the Rome III classification

  Suzuki, H., Nishizawa, T. & Hibi, T., 2006 Jun, In: Journal of gastroenterology. 41, 6, p. 513-523 11 p.

  Research output: Contribution to journal › Review article › peer-review
  68 Citations (Scopus)

• Therapeutic strategies for implantation failure due to endometrial dysfunction

  Maruyama, T., 2009 Oct 1, In: Journal of Mammalian Ova Research. 26, 3, p. 129-133 5 p.

  Research output: Contribution to journal › Review article › peer-review
  1 Citation (Scopus)

• Therapeutic strategies for severe alcoholic hepatitis

  Horie, Y., Yamagishi, Y., Ebinuma, H. & Hibi, T., 2011 Nov, In: Clinics and Research in Hepatology and Gastroenterology. 35, 11, p. 738-744 7 p.

  Research output: Contribution to journal › Article › peer-review
  15 Citations (Scopus)

• Therapeutic strategies targeting brain tumor stem cells

  Toda, M., 2009 Jul 1, In: Brain and Nerve. 61, 7, p. 799-803 5 p.

  Research output: Contribution to journal › Review article › peer-review
  1 Citation (Scopus)

• Therapeutic strategies targeting cancer stem cells

  Yoshida, G. J. & Saya, H., 2016 Jan 1, In: Cancer science. 107, 1, p. 5-11 7 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  154 Citations (Scopus)

• Therapeutic strategy for progressive renal disease

  Hayashi, K., Ozawa, Y. & Tokuyama, H., 2001 May, In: Nippon rinsho. Japanese journal of clinical medicine. 59, 5, p. 955-960 6 p.

  Research output: Contribution to journal › Review article › peer-review

• Therapeutic strategy for targeting aggressive malignant gliomas by disrupting their energy balance

  Hegazy, A. M., Yamada, D., Kobayashi, M., Kohno, S., Ueno, M., Ali, M. A. E., Ohta, K., Tadokoro, Y., Ino, Y., Todo, T., Soga, T., Takahashi, C. & Hirao, A., 2016 Oct 7, In: Journal of Biological Chemistry. 291, 41, p. 21496-21509 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  28 Citations (Scopus)

• Therapeutic strategy for the surgical treatment of eyelid disorders following facial nerve palsy

  Tanaka, I., Sakuma, T. & Shimizu, Y., 2014 May, In: Japanese Journal of Plastic Surgery. 57, 5, p. 465-472 8 p.

  Research output: Contribution to journal › Article › peer-review

• Therapeutic strategy for the treatment with hypertensive renal injury

  Hayashi, K., 2004 Jan, In: Nippon rinsho. Japanese journal of clinical medicine. 62, 1, p. 135-141 7 p.

  Research output: Contribution to journal › Review article › peer-review

• Therapeutic Targets for DOX-Induced Cardiomyopathy: Role of Apoptosis vs. Ferroptosis

  Kitakata, H., Endo, J., Ikura, H., Moriyama, H., Shirakawa, K., Katsumata, Y. & Sano, M., 2022 Feb 1, In: International journal of molecular sciences. 23, 3, 1414.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  9 Citations (Scopus)

• Therapeutic targets of misguided T cells in systemic lupus erythematosus

  Takeuchi, T., Tsuzaka, K., Kameda, H. & Amano, K., 2005 Jun, In: Current Drug Targets: Inflammation and Allergy. 4, 3, p. 295-298 4 p.

  Research output: Contribution to journal › Review article › peer-review
  7 Citations (Scopus)

• Therapeutic value of lymph node dissection during hepatectomy in patients with intrahepatic cholangiocellular carcinoma with negative lymph node involvement

  Shimada, K., Sano, T., Nara, S., Esaki, M., Sakamoto, Y., Kosuge, T. & Ojima, H., 2009 Apr, In: Surgery. 145, 4, p. 411-416 6 p.

  Research output: Contribution to journal › Article › peer-review
  98 Citations (Scopus)

• Therapeutic window for striatal dopamine D_2/3 receptor occupancy in older patients with schizophrenia: A pilot PET study

  Uchida, H., Suzuki, T., Graff-Guerrero, A., Mulsant, B. H., Pollock, B. G., Arenovich, T., Rajji, T. K. & Mamo, D. C., 2014 Oct 1, In: American Journal of Geriatric Psychiatry. 22, 10, p. 1007-1016 10 p.

  Research output: Contribution to journal › Article › peer-review
  23 Citations (Scopus)

• Therapeutic window for striatal dopamine D2/3 receptor occupancy in older patients with schizophrenia: A pilot PET study

  Uchida, H., Suzuki, T., Graff-Guerrero, A., Mulsant, B. H., Pollock, B. G., Arenovich, T., Rajji, T. K. & Mamo, D. C., 2012 Oct 31, (Accepted/In press) In: American Journal of Geriatric Psychiatry.

  Research output: Contribution to journal › Article › peer-review