Find Research outputs

Search results

• Article

  Activated hepatic stellate cells mediate the differentiation of macrophages

  Chang, J., Hisamatsu, T., Shimamura, K., Yoneno, K., Adachi, M., Naruse, H., Igarashi, T., Higuchi, H., Matsuoka, K., Kitazume, M. T., Ando, S., Kamada, N., Kanai, T. & Hibi, T., 2013 Jun, In: Hepatology Research. 43, 6, p. 658-669 12 p.

  Research output: Contribution to journal › Article › peer-review
  37 Citations (Scopus)

• Activated leukocytes and endothelial cells enhance retention of ultrasound contrast microspheres containing perfluoropropane in inflamed venules

  Yasu, T., Greener, Y., Jablonski, E., Killam, A. L., Fukuda, S., Suematsu, M., Tojo, S. J. & Schmid-Schönbein, G. W., 2005 Feb 15, In: International Journal of Cardiology. 98, 2, p. 245-252 8 p.

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)

• Activated macrophages promote Wnt signalling through tumour necrosis factor-α in gastric tumour cells

  Oguma, K., Oshima, H., Aoki, M., Uchio, R., Naka, K., Nakamura, S., Hirao, A., Saya, H., Taketo, M. M. & Oshima, M., 2008 Jun 18, In: EMBO Journal. 27, 12, p. 1671-1681 11 p.

  Research output: Contribution to journal › Article › peer-review
  243 Citations (Scopus)

• Activated phosphorylation of cyclic AMP response element binding protein is associated with preservation of striatal neurons after focal cerebral ischemia in the rat

  Tanaka, K., Nogawa, S., Ito, D., Suzuki, S., Dembo, T., Kosakai, A. & Fukuuchi, Y., 2000 Sep 14, In: Neuroscience. 100, 2, p. 345-354 10 p.

  Research output: Contribution to journal › Article › peer-review
  44 Citations (Scopus)

• Activated platelets and endothelial cell interaction with neutrophils under flow conditions

  Mine, S., Fujisaki, T., Suematsu, M. & Tanaka, Y., 2001, In: Internal Medicine. 40, 11, p. 1085-1092 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  37 Citations (Scopus)

• Activated prorenin as a therapeutic target for diabetic nephropathy

  Ichihara, A., Sakoda, M., Mito-Kurauchi, A. & Itoh, H., 2008 Nov 13, In: Diabetes Research and Clinical Practice. 82, SUPPL. 1, p. S63-S66

  Research output: Contribution to journal › Article › peer-review
  18 Citations (Scopus)

• Activated protein C induces endothelial cell proliferation by mitogen-activated protein kinase activation in vitro and angiogenesis in vivo

  Uchiba, M., Okajima, K., Oike, Y., Ito, Y., Fukudome, K., Isobe, H. & Suda, T., 2004 Jul 9, In: Circulation research. 95, 1, p. 34-41 8 p.

  Research output: Contribution to journal › Article › peer-review
  138 Citations (Scopus)

• Activating GNAS and KRAS mutations in gastric foveolar metaplasia, gastric heterotopia, and adenocarcinoma of the duodenum

  Matsubara, A., Ogawa, R., Suzuki, H., Oda, I., Taniguchi, H., Kanai, Y., Kushima, R. & Sekine, S., 2015 Apr 14, In: British Journal of Cancer. 112, 8, p. 1398-1404 7 p.

  Research output: Contribution to journal › Article › peer-review
  45 Citations (Scopus)

• Activating mutations of the Noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia

  Bentires-Alj, M., Paez, J. G., David, F. S., Keilhack, H., Halmos, B., Naoki, K., Maris, J. M., Richardson, A., Bardelli, A., Sagarbaker, D. J., Richards, W. G., Du, J., Girard, L., Minna, J. D., Loh, M. L., Fisher, D. E., Velculescu, V. E., Vogelstein, B., Meyerson, M., Sellers, W. R., & 1 othersNeel, B. G., 2004 Dec 15, In: Cancer Research. 64, 24, p. 8816-8820 5 p.

  Research output: Contribution to journal › Article › peer-review
  417 Citations (Scopus)

• Activation and function of cyclin T-Cdk9 (positive transcription elongation factor-b) in cardiac muscle-cell hypertrophy

  Sano, M., Abdellatif, M., Oh, H., Xie, M., Bagella, L., Giordano, A., Michael, L. H., DeMayo, F. J. & Schneider, M. D., 2002 Nov 1, In: Nature medicine. 8, 11, p. 1310-1317 8 p.

  Research output: Contribution to journal › Article › peer-review
  200 Citations (Scopus)

• Activation and proliferation of oligodendrocyte progenitor cells after brain ischemia in the rat

  Tanaka, K., Nogawa, S., Ito, D., Suzuki, S., Dembo, T. & Kosakai, A., 2003 Jun 1, In: International Congress Series. 1252, C, p. 435-444 10 p.

  Research output: Contribution to journal › Article › peer-review

• Activation and translocation of PKCδ is necessary for VEGF-induced ERK activation through KDR in HEK293T cells

  Kuriyama, M., Taniguchi, T., Shirai, Y., Sasaki, A., Yoshimura, A. & Saito, N., 2004 Dec 17, In: Biochemical and Biophysical Research Communications. 325, 3, p. 843-851 9 p.

  Research output: Contribution to journal › Article › peer-review
  23 Citations (Scopus)

• Activation energy calculations for formamide-TiO₂ and formamide-pt interactions in the presence of water

  Dushanov, E., Kholmurodov, K. & Yasuoka, K., 2013 Apr 17, In: Open Biochemistry Journal. 7, 1, p. 33-43 11 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Activation-induced cytidine deaminase deficiency causes organ-specific autoimmune disease

  Hase, K., Takahashi, D., Ebisawa, M., Kawano, S., Itoh, K. & Ohno, H., 2008 Aug 21, In: PloS one. 3, 8, e3033.

  Research output: Contribution to journal › Article › peer-review
  56 Citations (Scopus)

• Activation-induced cytidine deaminase expression in CD4 ⁺ T cells is associated with a unique IL-10-producing subset that increases with age

  Qin, H., Suzuki, K., Nakata, M., Chikuma, S., Izumi, N., Thi Huong, L., Maruya, M., Fagarasan, S., Busslinger, M., Honjo, T. & Nagaoka, H., 2011 Dec 28, In: PloS one. 6, 12, e29141.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  44 Citations (Scopus)

• Activation-induced cytidine deaminase is dispensable for virus-mediated liver and skin tumor development in mouse models

  Nguyen, T., Xu, J., Chikuma, S., Hiai, H., Kinoshita, K., Moriya, K., Koike, K., Marcuzzi, G. P., Pfister, H., Honjo, T. & Kobayashi, M., 2014 Jul, In: International immunology. 26, 7, p. 397-406 10 p., dxu040.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Activation Mechanism of N-Nitrosodialkylamines as Environmental Mutagens and Its Application to Antitumor Research

  Inami, K., Ishikawa, S., Mochizuki, M. & Ishikawa, S., 2009, In: Genes and Environment. 31, 4, p. 97-104 8 p.

  Research output: Contribution to journal › Article › peer-review
  11 Citations (Scopus)

• Activation of 5’-Deoxy-5-fluorouridine by Thymidine Phosphorylase in Human Tumors

  Kono, A., Hara, Y., Sugata, S., Karube, Y., Matsushima, Y. & Ishitsuka, H., 1983 Jan 1, In: Chemical and Pharmaceutical Bulletin. 31, 1, p. 175-178 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  172 Citations (Scopus)

• Activation of adenosine A₁ receptor-induced neural stem cell proliferation via MEK/ERK and Akt signaling pathways

  Migita, H., Kominami, K., Higashida, M., Maruyama, R., Tuchida, N., McDonald, F., Shimada, F. & Sakurada, K., 2008, In: Journal of neuroscience research. 86, 13, p. 2820-2828 9 p.

  Research output: Contribution to journal › Article › peer-review
  47 Citations (Scopus)

• Activation of a diluted E. coli cell-free transcription-translation system within liposomes by hypertonic concentration

  Matsui, Y., Akui, T., Doi, N. & Fujiwara, K., 2021 Dec 17, In: STAR Protocols. 2, 4, 101003.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Activation of a neutrophil-derived inflammatory response in the airways during cardiopulmonary bypass

  Kotani, T., Kotake, Y., Morisaki, H., Takeda, J., Shimizu, H., Ueda, T. & Ishizaka, A., 2006 Dec, In: Anesthesia and analgesia. 103, 6, p. 1394-1399 6 p.

  Research output: Contribution to journal › Article › peer-review
  12 Citations (Scopus)

• Activation of aniline by extracts from plants and induction of chromosomal damages in Chinese hamster ovary cells

  Kanaya, N., 1996, In: Genes and Genetic Systems. 71, 5, p. 319-322 4 p.

  Research output: Contribution to journal › Article › peer-review

• Activation of apoptosis by caspase-3-dependent specific RelB cleavage in anticancer agent-treated cancer cells: Involvement of positive feedback mechanism

  Kuboki, M., Ito, A., Simizu, S. & Umezawa, K., 2015 Jan 16, In: Biochemical and Biophysical Research Communications. 456, 3, p. 810-814 5 p.

  Research output: Contribution to journal › Article › peer-review
  7 Citations (Scopus)

• Activation of aryl hydrocarbon receptor promotes invasion of clear cell renal cell carcinoma and is associated with poor prognosis and cigarette smoke

  Ishida, M., Mikami, S., Shinojima, T., Kosaka, T., Mizuno, R., Kikuchi, E., Miyajima, A., Okada, Y. & Oya, M., 2015 Jul 15, In: International Journal of Cancer. 137, 2, p. 299-310 12 p.

  Research output: Contribution to journal › Article › peer-review
  27 Citations (Scopus)

• Activation of Boron-Doped Diamond Electrodes for Electrochemical CO₂Reduction in a Halogen-free Electrolyte

  Otake, A., Du, J. & Einaga, Y., 2022 Nov 7, In: ACS Sustainable Chemistry and Engineering. 10, 44, p. 14445-14450 6 p.

  Research output: Contribution to journal › Article › peer-review

• Activation of carboxyl groups by diphenyl 2-oxo-3-oxazolinylphosphonate. Facile preparation of versatile reagents, 3-acyl-2-oxazolones

  Kunieda, T., Higuchi, T., Abe, Y. & Hirobe, M., 1983, In: Tetrahedron. 39, 20, p. 3253-3260 8 p.

  Research output: Contribution to journal › Article › peer-review
  38 Citations (Scopus)

• Activation of cardiac Cdk9 represses PGC-1 and confers a predisposition to heart failure

  Sano, M., Wang, S. C., Shirai, M., Scaglia, F., Xie, M., Sakai, S., Tanaka, T., Kulkarni, P. A., Barger, P. M., Youker, K. A., Taffet, G. E., Hamamori, Y., Michael, L. H., Craigen, W. J. & Schneider, M. D., 2004 Sep 1, In: EMBO Journal. 23, 17, p. 3559-3569 11 p.

  Research output: Contribution to journal › Article › peer-review
  138 Citations (Scopus)

• Activation of caspase-12 by endoplasmic reticulum stress induced by transient middle cerebral artery occlusion in mice

  Shibata, M., Hattori, H., Sasaki, T., Gotoh, J., Hamada, J. & Fukuuchi, Y., 2003 May 8, In: Neuroscience. 118, 2, p. 491-499 9 p.

  Research output: Contribution to journal › Article › peer-review
  121 Citations (Scopus)

• Activation of CCAAT/enhancer-binding protein α or PU.1 in hematopoietic stem cells leads to their reduced self-renewal and proliferation

  Fukuchi, Y., Ito, M., Shibata, F., Kitamura, T. & Nakajima, H., 2008 Dec, In: Stem Cells. 26, 12, p. 3172-3181 10 p.

  Research output: Contribution to journal › Article › peer-review
  18 Citations (Scopus)

• Activation of Cdh1-dependent APC is required for G₁ cell cycle arrest and DNA damage-induced G₂ checkpoint in vertebrate cells

  Sudo, T., Ota, Y., Kotani, S., Nakao, M., Takami, Y., Takeda, S. & Saya, H., 2001 Nov 15, In: EMBO Journal. 20, 22, p. 6499-6508 10 p.

  Research output: Contribution to journal › Article › peer-review
  125 Citations (Scopus)

• Activation of cell migration via morphological changes in focal adhesions depends on shear stress in MYCN-amplified neuroblastoma cells

  Hiraiwa, T., Yamada, T. G., Miki, N., Funahashi, A. & Hiroi, N., 2019 Mar 1, In: Journal of the Royal Society Interface. 16, 152, 20180934.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Activation of c-Src kinase is associated with in vitro decidualization of human endometrial stromal cells

  Maruyama, T., Yoshimura, Y., Yodoi, J. & Sabe, H., 1999, In: Endocrinology. 140, 6, p. 2632-2636 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  31 Citations (Scopus)

• Activation of cytokine signaling through leukemia inhibitory factor receptor (LIFR)/gp130 attenuates ischemic brain injury in rats

  Suzuki, S., Yamashita, T., Tanaka, K., Hattori, H., Sawamoto, K., Okano, H. & Suzuki, N., 2005 Jun, In: Journal of Cerebral Blood Flow and Metabolism. 25, 6, p. 685-693 9 p.

  Research output: Contribution to journal › Article › peer-review
  44 Citations (Scopus)

• Activation of dendritic-like cells and neural stem/progenitor cells in injured spinal cord by GM-CSF

  Hayashi, K., Ohta, S., Kawakami, Y. & Toda, M., 2009 May, In: Neuroscience Research. 64, 1, p. 96-103 8 p.

  Research output: Contribution to journal › Article › peer-review
  35 Citations (Scopus)

• Activation of EGFR bypass signaling by TGFa overexpression induces acquired resistance to alectinib in ALK-translocated lung cancer cells

  Tani, T., Yasuda, H., Hamamoto, J., Kuroda, A., Arai, D., Ishioka, K., Ohgino, K., Miyawaki, M., Kawada, I., Naoki, K., Hayashi, Y., Betsuyaku, T. & Soejima, K., 2016 Jan 1, In: Molecular cancer therapeutics. 15, 1, p. 162-171 10 p.

  Research output: Contribution to journal › Article › peer-review
  44 Citations (Scopus)

• Activation of extracellular signal-regulated kinase in the trigeminal ganglion following both treatment of the dura mater with capsaicin and cortical spreading depression

  Iwashita, T., Shimizu, T., Shibata, M., Toriumi, H., Ebine, T., Funakubo, M. & Suzuki, N., 2013 Sep, In: Neuroscience Research. 77, 1-2, p. 110-119 10 p.

  Research output: Contribution to journal › Article › peer-review
  20 Citations (Scopus)

• Activation of extracellular signal-regulated kinase is associated with hepatocellular carcinoma with aggressive phenotypes

  Minagawa, T., Yamazaki, K., Masugi, Y., Tsujikawa, H., Ojima, H., Hibi, T., Abe, Y., Yagi, H., Kitago, M., Shinoda, M., Itano, O., Kitagawa, Y. & Sakamoto, M., 2020 Mar 1, In: Hepatology Research. 50, 3, p. 353-364 12 p.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• Activation of heparanase by ultraviolet B irradiation leads to functional loss of basement membrane at the dermal-epidermal junction in human skin

  Iriyama, S., Matsunaga, Y., Takahashi, K., Matsuzaki, K., Kumagai, N. & Amano, S., 2011 May, In: Archives of Dermatological Research. 303, 4, p. 253-261 9 p.

  Research output: Contribution to journal › Article › peer-review
  30 Citations (Scopus)

• Activation of human neutrophils by Arg‐Gly‐Asp‐Ser immobilized on microspheres

  Kasuya, Y., Fujimoto, K., Miyamoto, M. & Kawaguchi, H., 1994 Mar, In: Journal of Biomedical Materials Research. 28, 3, p. 397-404 8 p.

  Research output: Contribution to journal › Article › peer-review
  12 Citations (Scopus)

• Activation of JNK triggers release of Brd4 from mitotic chromosomes and mediates protection from drug-induced mitotic stress

  Nishiyama, A., Dey, A., Tamura, T., Ko, M. & Ozato, K., 2012 May 2, In: PloS one. 7, 5, e34719.

  Research output: Contribution to journal › Article › peer-review
  7 Citations (Scopus)

• Activation of matrix metalloproteinase-2 in head and neck squamous cell carcinoma: Studies of clinical samples and in vitro cell lines co-cultured with fibroblasts

  Tokumaru, Y., Fujii, M., Otani, Y., Kameyama, K., Imanishi, Y., Igarashi, N. & Kanzaki, J., 2000 Mar 13, In: Cancer Letters. 150, 1, p. 15-21 7 p.

  Research output: Contribution to journal › Article › peer-review
  38 Citations (Scopus)

• Activation of matrix metalloproteinase 3 (stromelysin) and matrix metalloproteinase 2 ('gelatinase') by human neutrophil elastase and cathepsin G

  Okada, Y. & Nakanishi, I., 1989 Jun 5, In: FEBS Letters. 249, 2, p. 353-356 4 p.

  Research output: Contribution to journal › Article › peer-review
  147 Citations (Scopus)

• Activation of m-Calpain Is Required for Chromosome Alignment on the Metaphase Plate during Mitosis

  Honda, S., Marumoto, T., Hirota, T., Nitta, M., Arima, Y., Ogawa, M. & Saya, H., 2004 Mar 12, In: Journal of Biological Chemistry. 279, 11, p. 10615-10623 9 p.

  Research output: Contribution to journal › Article › peer-review
  36 Citations (Scopus)

• Activation of murine cytomegalovirus immediate-early promoter in cerebral ventricular zone and glial progenitor cells in transgenic mice

  Li, R. Y., Baba, S., Kosugi, I., Arai, Y., Kawasaki, H., Shinmura, Y., Sakakibara, S. I., Okano, H. & Tsutsui, Y., 2001, In: Glia. 35, 1, p. 41-52 12 p.

  Research output: Contribution to journal › Article › peer-review
  20 Citations (Scopus)

• Activation of natural killer T cells by α-galactosylceramide impairs DNA vaccine-induced protective immunity against Trypanosoma cruzi

  Miyahira, Y., Katae, M., Takeda, K., Yagita, H., Okumura, K., Kobayashi, S., Takeuchi, T., Kamiyama, T., Fukuchi, Y. & Aoki, T., 2003 Mar 1, In: Infection and Immunity. 71, 3, p. 1234-1241 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  37 Citations (Scopus)

• Activation of Neutrophil-like Cells Stimulated by Polymer Surfaces

  Fujimoto, K., Sasaki, J., Tomida, Y., Wakabayashi, Y. & Kawaguchi, H., 1998, In: KOBUNSHI RONBUNSHU. 55, 6, p. 367-371 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Activation of NG2-positive oligodendrocyte progenitor cells during post-ischemic reperfusion in the rat brain

  Tanaka, K., Nogawa, S., Ito, D., Suzuki, S., Dembo, T., Kosakai, A. & Fukuuchi, Y., 2001 Jul 20, In: NeuroReport. 12, 10, p. 2169-2174 6 p.

  Research output: Contribution to journal › Article › peer-review
  65 Citations (Scopus)

• Activation of peroxisome proliferator-activated receptor δ induces fatty acid β-oxidation in skeletal muscle and attenuates metabolic syndrome

  Tanaka, T., Yamamoto, J., Iwasaki, S., Asaba, H., Hamura, H., Ikeda, Y., Watanabe, M., Magoori, K., Ioka, R. X., Tachibana, K., Watanabe, Y., Uchiyama, Y., Sumi, K., Iguchi, H., Ito, S., Doi, T., Hamakubo, T., Naito, M., Auwerx, J., Yanagisawa, M., & 2 othersKodama, T. & Sakai, J., 2003 Dec 23, In: Proceedings of the National Academy of Sciences of the United States of America. 100, 26, p. 15924-15929 6 p.

  Research output: Contribution to journal › Article › peer-review
  731 Citations (Scopus)

• Activation of preformed EGF receptor dimers by ligand-induced rotation of the transmembrane domain

  Moriki, T., Maruyama, H. & Maruyama, I. N., 2001 Aug 31, In: Journal of Molecular Biology. 311, 5, p. 1011-1026 16 p.

  Research output: Contribution to journal › Article › peer-review
  277 Citations (Scopus)

• Activation of pro-MMP-2 mediated by MT1-MMP in human salivary gland carcinomas: Possible regulation of pro-MMP-2 activation by TIMP-2

  Kayano, K., Shimada, T., Shinomiya, T., Nakai, S., Hisa, Y., Aoki, T., Seiki, M. & Okada, Y., 2004 Apr 1, In: Journal of Pathology. 202, 4, p. 403-411 9 p.

  Research output: Contribution to journal › Article › peer-review
  31 Citations (Scopus)