A biointerface effect on the self-assembly of ribonucleic acids: A possible mechanism of RNA polymerisation in the self-replication cycle

Noriyoshi Arai, Yusei Kobayashi, Kenji Yasuoka

Research output: Contribution to journalArticle


Despite decades of intensive research, many questions remain on the formation and growth of the first cells on Earth. Here, we used computer simulation to compare the self-assembly process of ribonucleic acids in two environments: Enclosed in a vesicle-cell membrane and in the bulk. The self-assembly was found to be more favoured in the former environment, and the origin of such a biointerface effect was identified. These results will contribute to a better understanding of the origin of life on the primitive Earth.

Original languageEnglish
Pages (from-to)6691-6698
Number of pages8
Issue number12
Publication statusPublished - 2020 Mar 28


ASJC Scopus subject areas

  • Materials Science(all)

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