A case of a granular cell tumor of the stomach with gradual enlargement during a 30 month-follow-up

Motohiko Kato; Tsutomu Nishida; Eiichi Morii; Yumiko Hori; Yoshito Hayashi; Shunsuke Yamamoto; Hideki Iijima; Shusaku Tsutsui; Masahiko Tsujii; Tetsuo Takehara

A case of a granular cell tumor of the stomach with gradual enlargement during a 30 month-follow-up

Motohiko Kato, Tsutomu Nishida, Eiichi Morii, Yumiko Hori, Yoshito Hayashi, Shunsuke Yamamoto, Hideki Iijima, Shusaku Tsutsui, Masahiko Tsujii, Tetsuo Takehara

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

A 46-year-old woman with a gastric submucosal tumor (SMT) had been followed up with endoscopy for 30 months in our hospital. The SMT showed gradual enlargement during the follow-up period. EUS revealed the submucosal layer was maintained beneath the SMT which was located between the mucosa and submucosa. Because malignancy could not be ruled out, endoscopic submucosal dissection (ESD) was performed for the purpose of a "total biopsy" and the lesion was resected en bloc. Immunohistochemical findings revealed that the tumor was negative for SMA, KIT, CD34, and positive for S-100. It was also positive for PAS stain. The MIB-1 index was around 5%. Thus, the tumor was pathologically diagnosed as a benign granular cell tumor of the stomach. We conclude that the combination of EUS and ESD is useful for the diagnosis and treatment of SMTs above the submucosal layer such as granular cell tumors.

Original language	English
Pages (from-to)	1819-1826
Number of pages	8
Journal	GASTROENTEROLOGICAL ENDOSCOPY
Volume	54
Issue number	6
Publication status	Published - 2012 Jun
Externally published	Yes

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Gastroenterology

Cite this

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title = "A case of a granular cell tumor of the stomach with gradual enlargement during a 30 month-follow-up",

abstract = "A 46-year-old woman with a gastric submucosal tumor (SMT) had been followed up with endoscopy for 30 months in our hospital. The SMT showed gradual enlargement during the follow-up period. EUS revealed the submucosal layer was maintained beneath the SMT which was located between the mucosa and submucosa. Because malignancy could not be ruled out, endoscopic submucosal dissection (ESD) was performed for the purpose of a {"}total biopsy{"} and the lesion was resected en bloc. Immunohistochemical findings revealed that the tumor was negative for SMA, KIT, CD34, and positive for S-100. It was also positive for PAS stain. The MIB-1 index was around 5%. Thus, the tumor was pathologically diagnosed as a benign granular cell tumor of the stomach. We conclude that the combination of EUS and ESD is useful for the diagnosis and treatment of SMTs above the submucosal layer such as granular cell tumors.",

author = "Motohiko Kato and Tsutomu Nishida and Eiichi Morii and Yumiko Hori and Yoshito Hayashi and Shunsuke Yamamoto and Hideki Iijima and Shusaku Tsutsui and Masahiko Tsujii and Tetsuo Takehara",

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language = "English",

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T1 - A case of a granular cell tumor of the stomach with gradual enlargement during a 30 month-follow-up

AU - Kato, Motohiko

AU - Nishida, Tsutomu

AU - Morii, Eiichi

AU - Hori, Yumiko

AU - Hayashi, Yoshito

AU - Yamamoto, Shunsuke

AU - Iijima, Hideki

AU - Tsutsui, Shusaku

AU - Tsujii, Masahiko

AU - Takehara, Tetsuo

PY - 2012/6

Y1 - 2012/6

N2 - A 46-year-old woman with a gastric submucosal tumor (SMT) had been followed up with endoscopy for 30 months in our hospital. The SMT showed gradual enlargement during the follow-up period. EUS revealed the submucosal layer was maintained beneath the SMT which was located between the mucosa and submucosa. Because malignancy could not be ruled out, endoscopic submucosal dissection (ESD) was performed for the purpose of a "total biopsy" and the lesion was resected en bloc. Immunohistochemical findings revealed that the tumor was negative for SMA, KIT, CD34, and positive for S-100. It was also positive for PAS stain. The MIB-1 index was around 5%. Thus, the tumor was pathologically diagnosed as a benign granular cell tumor of the stomach. We conclude that the combination of EUS and ESD is useful for the diagnosis and treatment of SMTs above the submucosal layer such as granular cell tumors.

AB - A 46-year-old woman with a gastric submucosal tumor (SMT) had been followed up with endoscopy for 30 months in our hospital. The SMT showed gradual enlargement during the follow-up period. EUS revealed the submucosal layer was maintained beneath the SMT which was located between the mucosa and submucosa. Because malignancy could not be ruled out, endoscopic submucosal dissection (ESD) was performed for the purpose of a "total biopsy" and the lesion was resected en bloc. Immunohistochemical findings revealed that the tumor was negative for SMA, KIT, CD34, and positive for S-100. It was also positive for PAS stain. The MIB-1 index was around 5%. Thus, the tumor was pathologically diagnosed as a benign granular cell tumor of the stomach. We conclude that the combination of EUS and ESD is useful for the diagnosis and treatment of SMTs above the submucosal layer such as granular cell tumors.

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SN - 0387-1207

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JO - Gastroenterological Endoscopy

JF - Gastroenterological Endoscopy

IS - 6

ER -

A case of a granular cell tumor of the stomach with gradual enlargement during a 30 month-follow-up

Abstract

ASJC Scopus subject areas

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