A case of acute lymphocytic leukemia with bilateral optic symptoms to those of ischemic optic neuropathy after bone marrow transplantation

Chiharu Takeda, Yukihiko Mashima, Saburousuke Suzuki, Sinichiro Okamoto

Research output: Contribution to journalArticle


We report a case of acute lymphocytic leukemia with bilateral optic symptoms that were similar to those of ischemic optic neuropathy. A 37-year- old female noticed a visual defect in her right eye 50 days after allogeneic marrow transplantation, when she reached complete hematologic remission. Because radiation was effective in relieving her symptoms, we concluded that they were due to leukemic optic neuropathy. Eight months after the onset of symptoms in the right eye, however, the same symptoms appeared in the other eye. Because radiation was not effective and steroid drugs were effective, it is presumed that graft versus host disease may have contributed to this patient's symptoms.

Original languageEnglish
Pages (from-to)638-643
Number of pages6
JournalFolia Ophthalmologica Japonica
Issue number7
Publication statusPublished - 1998 Jul 1



  • Acute Lymphocytic Leukemia
  • Cyclosporine-A
  • Graft-Versus-Host Disease
  • Ischemic Optic Neuropathy
  • Leukemic Optic Neuropathy

ASJC Scopus subject areas

  • Ophthalmology

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