A case of autoimmune polyglandular syndrome type 3 with plasma glucose and c-peptide levels observed before and after diabetes onset

Yukie Soeda, Kumiko Tanaka, Yoshifumi Saisho, Shu Meguro, Akira Shimada, Toshihide Kawai, Hiroshi Itoh

Research output: Contribution to journalArticle

Abstract

Changes in metabolic parameters before type 1 diabetes onset remain unclear, so we report the case of a natural history of adult-onset type 1 diabetes. A 59-year-old man with autoimmune polyglandular syndrome type 3 had his plasma glucose and C-peptide levels observed before and after diabetes onset. He was diagnosed with Hashimoto disease in 1991, and LT 4 replacement therapy was started. Due to weight gain, levels of plasma glucose, C-peptide, and glycosylated hemoglobin were measured since 2002. In 2005, he was hospitalized for diabetic ketoacidosis, and insulin therapy was started. We then confirmed that he was positive for islet-related autoantibodies and diagnosed him with type 1 diabetes.

Original languageEnglish
Pages (from-to)340-344
Number of pages5
JournalJournal of the Japan Diabetes Society
Volume55
Issue number5
Publication statusPublished - 2012 May 30

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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