A case of Castleman's disease associated with diffuse idiopathic skeletal hyperostosis and ossification of the posterior longitudinal ligament of the spine

Shu Kobayashi, Shigeki Momohara, Katsunori Ikari, Takeshi Mochizuki, Koichiro Kawamura, So Tsukahara, Kazumasa Nishimoto, Hiroshi Okamoto, Taisuke Tomatsu

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Castleman's disease (CD), diffuse idiopathic skeletal hyperostosis (DISH), and ossification of the posterior longitudinal ligament of the spine (OPLL) are three different entities. Castleman's disease displaying a variety of calcifications in the abdomen and/or pelvis has been reported in some papers. However, there were no reports suggesting an association between CD and ossification/calcification in spine and joints. So far, there has been no case report regarding the coexistence of these diseases in the literature. Herein, we detail a 75-year-old man suffering from CD who demonstrated the features of DISH with coexisting features of OPLL. The cardinal symptoms such as fatigue, high fever, and swollen glands in this case were reduced by corticosteroid therapy. However, it is possible to produce actual symptoms of ossifying/ calcified diathesis of entheses and ligaments as a consequence, like the pathology of calcification found in the region of the spleen. In this paper, we describe this patient in order to discuss the association of these diseases.

Original languageEnglish
Pages (from-to)418-421
Number of pages4
JournalModern Rheumatology
Volume17
Issue number5
DOIs
Publication statusPublished - 2007 Oct
Externally publishedYes

Fingerprint

Diffuse Idiopathic Skeletal Hyperostosis
Giant Lymph Node Hyperplasia
Spine
Longitudinal Ligaments
Disease Susceptibility
Pelvis
Ligaments
Osteogenesis
Abdomen
Fatigue
Adrenal Cortex Hormones
Fever
Spleen
Joints
Pathology
Ossification of the posterior longitudinal ligament of the spine

Keywords

  • Calcification
  • Castleman's disease
  • Diffuse idiopathic skeletal hyperostosis (DISH)
  • Ossificationof the posterior longitudinal ligament of the spine (OPLL)

ASJC Scopus subject areas

  • Rheumatology
  • Immunology

Cite this

A case of Castleman's disease associated with diffuse idiopathic skeletal hyperostosis and ossification of the posterior longitudinal ligament of the spine. / Kobayashi, Shu; Momohara, Shigeki; Ikari, Katsunori; Mochizuki, Takeshi; Kawamura, Koichiro; Tsukahara, So; Nishimoto, Kazumasa; Okamoto, Hiroshi; Tomatsu, Taisuke.

In: Modern Rheumatology, Vol. 17, No. 5, 10.2007, p. 418-421.

Research output: Contribution to journalArticle

Kobayashi, Shu ; Momohara, Shigeki ; Ikari, Katsunori ; Mochizuki, Takeshi ; Kawamura, Koichiro ; Tsukahara, So ; Nishimoto, Kazumasa ; Okamoto, Hiroshi ; Tomatsu, Taisuke. / A case of Castleman's disease associated with diffuse idiopathic skeletal hyperostosis and ossification of the posterior longitudinal ligament of the spine. In: Modern Rheumatology. 2007 ; Vol. 17, No. 5. pp. 418-421.
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