A case of gastric cancer with multiple liver metastasis responding to combined chemotherapy with low-dose cisplatin and 5-fluorouracil

H. Shinkawa, N. Wada, S. Naka, H. Yasuhara, T. Kuroda, T. Nojiri, T. Inoue, T. Fujita, Y. Furuya, K. Okazaki, T. Nagao, K. Nagao

Research output: Contribution to journalArticle

Abstract

A 68-year-old man who had Borrmann type 4 gastric cancer with multiple liver metastases was admitted to our hospital on October 20, 1998. He was considered nonresectable and placed on neoadjuvant chemotherapy consisting of low-dose CDDP and 5-FU. After 9 weeks of administration, the liver metastases had disappeared on abdominal computed tomography, but the primary lesion had progressed. On May 12, 1999, a total gastrectomy with a partial resection of the transverse colon and resectional biopsy of a white nodule of the liver were performed. This was a non-curative operation because of the peritoneal dissemination. A histopathological examination of the liver nodule revealed that the cancer cells had disappeared. The patient had an uneventful postoperative course and 4 weeks of chemotherapy were added. He remains alive with no symptoms or re-growth of the liver metastatic tumor 4 months after the surgery.

Original languageEnglish
Pages (from-to)909-913
Number of pages5
JournalGan to kagaku ryoho. Cancer & chemotherapy
Volume27
Issue number6
Publication statusPublished - 2000 Jun
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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    Shinkawa, H., Wada, N., Naka, S., Yasuhara, H., Kuroda, T., Nojiri, T., Inoue, T., Fujita, T., Furuya, Y., Okazaki, K., Nagao, T., & Nagao, K. (2000). A case of gastric cancer with multiple liver metastasis responding to combined chemotherapy with low-dose cisplatin and 5-fluorouracil. Gan to kagaku ryoho. Cancer & chemotherapy, 27(6), 909-913.