A case of inoperable advanced gastric cancer remarkably responding to combined chemotherapy with UFT-E, MMC and PSK

A. Kogure, S. Ishii, T. Kakefuda, K. Aiura, Y. Arisawa, Y. Kitagawa, M. Nakagawa, N. Shirasugi, K. Noga

Research output: Contribution to journalArticle

Abstract

A 55-year-old male consulted a local doctor with the complaint of epigastralgia. Examination of the upper gastrointestinal tract revealed gastric cancer (Borrmann Type II) and he was referred to our hospital for operation. A few lymph nodes were palpable in the left supraclavicular fossa, and the biopsy of those lymph nodes revealed metastatic adenocarcinoma. The CT scan of the abdomen showed enlargement of paraaortic lymph nodes. Then, the patient was determined inoperable (T3, N4, H0, P0, M1 stage IVb). He was treated as an outpatient with UFT-E (300 mg/day, orally), Krestin (PSK 3.0 g/day, orally) and Mitomycin C (MMC 6 or 8 mg once a week, intravenously repeated interval of 4 weeks). The total dose of UFT-E, PSK and MMC was 219 g, 1,095 g and 136 mg, respectively. One month later, lymph nodes in the supraclavicular fossa disappeared, and the lesion in the stomach completely responded. We have followed the patient for more than one year. He visits our the outpatient department and has kept working until now.

Original languageEnglish
Pages (from-to)875-878
Number of pages4
JournalJapanese Journal of Cancer and Chemotherapy
Volume24
Issue number7
Publication statusPublished - 1997 Sep 24
Externally publishedYes

Keywords

  • Combined chemotherapy
  • Inoperative gastric cancer
  • Virchow lymph node metastasis

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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  • Cite this

    Kogure, A., Ishii, S., Kakefuda, T., Aiura, K., Arisawa, Y., Kitagawa, Y., Nakagawa, M., Shirasugi, N., & Noga, K. (1997). A case of inoperable advanced gastric cancer remarkably responding to combined chemotherapy with UFT-E, MMC and PSK. Japanese Journal of Cancer and Chemotherapy, 24(7), 875-878.