A case of metastatic colon cancer effectively treated by XELOX and IRIS

Toshihiro Nishizawa, Satoshi Kinoshita, Takashi Sakuno, Yoichi Fujiyama, Miho Kikuchi, Hiroshi Kaneko, Hidekazu Suzuki, Masahiko Takahashi

Research output: Contribution to journalArticle

Abstract

The patient was a 78-year-old woman who suffered from right upper quadrant pain. She was diagnosed as colon cancer with hepatic metastasis. Initial chemotherapy using capecitabine plus oxaliplatin (XELOX)+bevacizumab achieved partial response. After 12 months, XELOX was discontinued due to Grade 3 hand-foot syndrome and peripheral neuropathy. Irinotecan plus oral S-1 (a combination of tegafur, 5-chloro-2, 4-dihydroxypyridine, and potassium oxonate) and (IRIS)+bevacizumab were continued as second-line therapy, and her status was maintained as stable disease. XELOX and IRIS regimens do not require catheter placement and long infusion process, providing a great advantage to patients.

Original languageEnglish
Pages (from-to)807-809
Number of pages3
JournalJapanese Journal of Cancer and Chemotherapy
Volume40
Issue number6
Publication statusPublished - 2013 Jun

Fingerprint

Colonic Neoplasms
oxaliplatin
irinotecan
Hand-Foot Syndrome
Tegafur
Peripheral Nervous System Diseases
Catheters
Neoplasm Metastasis
Drug Therapy
Pain
Liver
XELOX
Bevacizumab
Therapeutics
S 1 (combination)
gimeracil
Capecitabine
potassium oxonate

Keywords

  • Colon cancer
  • IRIS
  • XELOX

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Nishizawa, T., Kinoshita, S., Sakuno, T., Fujiyama, Y., Kikuchi, M., Kaneko, H., ... Takahashi, M. (2013). A case of metastatic colon cancer effectively treated by XELOX and IRIS. Japanese Journal of Cancer and Chemotherapy, 40(6), 807-809.

A case of metastatic colon cancer effectively treated by XELOX and IRIS. / Nishizawa, Toshihiro; Kinoshita, Satoshi; Sakuno, Takashi; Fujiyama, Yoichi; Kikuchi, Miho; Kaneko, Hiroshi; Suzuki, Hidekazu; Takahashi, Masahiko.

In: Japanese Journal of Cancer and Chemotherapy, Vol. 40, No. 6, 06.2013, p. 807-809.

Research output: Contribution to journalArticle

Nishizawa, T, Kinoshita, S, Sakuno, T, Fujiyama, Y, Kikuchi, M, Kaneko, H, Suzuki, H & Takahashi, M 2013, 'A case of metastatic colon cancer effectively treated by XELOX and IRIS', Japanese Journal of Cancer and Chemotherapy, vol. 40, no. 6, pp. 807-809.
Nishizawa T, Kinoshita S, Sakuno T, Fujiyama Y, Kikuchi M, Kaneko H et al. A case of metastatic colon cancer effectively treated by XELOX and IRIS. Japanese Journal of Cancer and Chemotherapy. 2013 Jun;40(6):807-809.
Nishizawa, Toshihiro ; Kinoshita, Satoshi ; Sakuno, Takashi ; Fujiyama, Yoichi ; Kikuchi, Miho ; Kaneko, Hiroshi ; Suzuki, Hidekazu ; Takahashi, Masahiko. / A case of metastatic colon cancer effectively treated by XELOX and IRIS. In: Japanese Journal of Cancer and Chemotherapy. 2013 ; Vol. 40, No. 6. pp. 807-809.
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