A case of metastatic colon cancer effectively treated by XELOX and IRIS

Toshihiro Nishizawa, Satoshi Kinoshita, Takashi Sakuno, Yoichi Fujiyama, Miho Kikuchi, Hiroshi Kaneko, Hidekazu Suzuki, Masahiko Takahashi

Research output: Contribution to journalArticle


The patient was a 78-year-old woman who suffered from right upper quadrant pain. She was diagnosed as colon cancer with hepatic metastasis. Initial chemotherapy using capecitabine plus oxaliplatin (XELOX)+bevacizumab achieved partial response. After 12 months, XELOX was discontinued due to Grade 3 hand-foot syndrome and peripheral neuropathy. Irinotecan plus oral S-1 (a combination of tegafur, 5-chloro-2, 4-dihydroxypyridine, and potassium oxonate) and (IRIS)+bevacizumab were continued as second-line therapy, and her status was maintained as stable disease. XELOX and IRIS regimens do not require catheter placement and long infusion process, providing a great advantage to patients.

Original languageEnglish
Pages (from-to)807-809
Number of pages3
JournalJapanese Journal of Cancer and Chemotherapy
Issue number6
Publication statusPublished - 2013 Jun



  • Colon cancer
  • IRIS

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Nishizawa, T., Kinoshita, S., Sakuno, T., Fujiyama, Y., Kikuchi, M., Kaneko, H., Suzuki, H., & Takahashi, M. (2013). A case of metastatic colon cancer effectively treated by XELOX and IRIS. Japanese Journal of Cancer and Chemotherapy, 40(6), 807-809.