A case of nasopharyngeal carcinoma ex pleomorphic adenoma

Koichiro Wasano, Yuichi Ikari, Sayuri Hashiguchi, Noriomi Suzuki, Taiji Kawasaki, Hiroyuki Ozawa

Research output: Contribution to journalArticle

Abstract

Malignant tumors of the minor salivary glands are very rare and most cases occur in the oral cavity, e.g., the palate, tongue, cheek and lip. We report herein on an extremely rare case of carcinoma ex pleomorphic adenoma arising in the fossa of Rosenmuller. An 83-year-old man, who had consulted another clinic with a complaint of hemosputum, was referred to our hospital because of the presence of a nasopharyngeal tumor. The tumor was resected via a transnasal endoscopic procedure without any major complications. The tumor was found to have arisen in the fossa of Rosenmuller and extended to superior lateral side behind the Eustachian tube cartilage. Histological examination showed that the main part of the tumor consisted of a pleomorphic adenoma, however, capsular invasion, nuclear atypia and mitosis were observed in a limited area where the MIB-1 index was high. We diagnosed the lesion as a carcinoma ex pleomorphic adenoma. We did not perform any postoperative therapy, because the area containing malignancy was far from the surgical margin and the patient was rather elderly. Three years and 10 months after the surgery, he remains in follow-up and has not shown any recurrence of the tumor.

Original languageEnglish
Pages (from-to)1083-1088
Number of pages6
JournalPractica Oto-Rhino-Laryngologica
Volume106
Issue number12
DOIs
Publication statusPublished - 2013

Fingerprint

Pleomorphic Adenoma
Neoplasms
Minor Salivary Glands
Carcinoma
Eustachian Tube
Palate
Cheek
Lip
Nasopharyngeal carcinoma
Tongue
Mitosis
Cartilage
Mouth
Recurrence

Keywords

  • Carcinoma ex pleomorphic adenoma
  • Minor salivary glands
  • Nasopharynx
  • Rosenmuller

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Wasano, K., Ikari, Y., Hashiguchi, S., Suzuki, N., Kawasaki, T., & Ozawa, H. (2013). A case of nasopharyngeal carcinoma ex pleomorphic adenoma. Practica Oto-Rhino-Laryngologica, 106(12), 1083-1088. https://doi.org/10.5631/jibirin.106.1083

A case of nasopharyngeal carcinoma ex pleomorphic adenoma. / Wasano, Koichiro; Ikari, Yuichi; Hashiguchi, Sayuri; Suzuki, Noriomi; Kawasaki, Taiji; Ozawa, Hiroyuki.

In: Practica Oto-Rhino-Laryngologica, Vol. 106, No. 12, 2013, p. 1083-1088.

Research output: Contribution to journalArticle

Wasano, K, Ikari, Y, Hashiguchi, S, Suzuki, N, Kawasaki, T & Ozawa, H 2013, 'A case of nasopharyngeal carcinoma ex pleomorphic adenoma', Practica Oto-Rhino-Laryngologica, vol. 106, no. 12, pp. 1083-1088. https://doi.org/10.5631/jibirin.106.1083
Wasano, Koichiro ; Ikari, Yuichi ; Hashiguchi, Sayuri ; Suzuki, Noriomi ; Kawasaki, Taiji ; Ozawa, Hiroyuki. / A case of nasopharyngeal carcinoma ex pleomorphic adenoma. In: Practica Oto-Rhino-Laryngologica. 2013 ; Vol. 106, No. 12. pp. 1083-1088.
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