A case of persistent elevation of serum glutamic oxaloacetic transaminase due to enzyme-immunoglobulin complex formation

Shinzo Kato, Hiromasa Ishii, Toshikazu Takagi, Yoshiaki Asaba, Makoto Ichijo, Masaharu Tsuchiya, Shojiro Kano, Mieko Saga, Kouji Horii

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A 43 year-old male, who has no complaints, was admitted for the evaluation of the persistent elevation of serum Glutamic Oxaloacetic Transaminase (GOT) activity. He showed slight hepatomegaly, but no other abnormal findings in physical examination. The abnormal laboratory finding was found only in serum GOT level, and other tests including ECG, EMG, ICG-15 min, liver scintigram and histology of biopsied liver were normal. By using electrophoresis and immunofixation technique, we found that serum GOT was bound to immunoglobulin IgG (A) and formed enzyme-immunogolbulin complex. Elevation of serum GOT seemed to be derived from the delayed disappearance rate of GOT from the blood, and not from the increase in release of GOT from the tissues.

Original languageEnglish
Pages (from-to)664-668
Number of pages5
JournalActa Hepatologica Japonica
Volume24
Issue number6
DOIs
Publication statusPublished - 1983 Jan

ASJC Scopus subject areas

  • Hepatology

Fingerprint Dive into the research topics of 'A case of persistent elevation of serum glutamic oxaloacetic transaminase due to enzyme-immunoglobulin complex formation'. Together they form a unique fingerprint.

  • Cite this