A case of pleomorphic carcinoma with jejunum mesenterium metastasis

Akane Yoshikawa, Katsuhiko Naoki, Jun Ichi Nitadori, Tomoki Fujii, Hiroaki Okamoto, Koshiro Watanabe

Research output: Contribution to journalArticle

Abstract

Background. Pleomorphic carcinoma of the lung is a rare primary pulmonary malignancy and has a poor prognosis. Lung cancer has a low frequency of metastasis to the gastrointestinal tract to the metastasis (8.8%), but some reported that pleomorphic carcinoma of lung has relatively higher gastrointestinal tract metastasis compared to other lung cancer. Case. A 59-year-old man presented with an abnormal chest shadow. He underwent bronchoscopy and non-small cell lung carcinoma was diagnosed. The tumor was completely resected in May 2006, with right upper lobectomy and lymph node resection. The definitive pathological diagnosis was pleomorphic carcinoma of the lung, pathological stage IB. In July 2007, he had a low fever and elevated tumor marker (SCC), PET scan revealed upper abdominal tumor with 15 cm in with no abdominal symptoms. The abdominal tumor was resected and was diagnosed as mesenterium metastasis. Systemic chemotherapy was planned but without having chemotherapy his disease progressed and he died within 3 months with multiple organ dysfunction. Conclusion. We studied metastasis in 30 cases of pleomorphic carcinoma of the lung reported in Japan after 1999 at the time of the WHO revision. Twenty cases with 46 metastases were reported and the highest was gastrointestinal tract metastasis (20%) much higher than that of lung cancer in general (8.8%). Cases of gastrointestinal tract metastasis often present with acute abdomen, therefore it is recommended that abdominal symptoms should be carefully observed during the follow-up of pleomorphic carcinoma of the lung.

Original languageEnglish
Pages (from-to)187-192
Number of pages6
JournalJapanese Journal of Lung Cancer
Volume49
Issue number2
DOIs
Publication statusPublished - 2009 Apr

Fingerprint

Jejunum
Neoplasm Metastasis
Carcinoma
Lung
Gastrointestinal Tract
Lung Neoplasms
Neoplasms
Drug Therapy
Acute Abdomen
Bronchoscopy
Tumor Biomarkers
Non-Small Cell Lung Carcinoma
Positron-Emission Tomography
Japan
Fever
Thorax
Lymph Nodes

Keywords

  • Gastrointestinal tract metastasis
  • Lung cancer
  • Mesenterium metastasis
  • Pleomorphic carcinoma of the lung

ASJC Scopus subject areas

  • Oncology
  • Pulmonary and Respiratory Medicine

Cite this

Yoshikawa, A., Naoki, K., Nitadori, J. I., Fujii, T., Okamoto, H., & Watanabe, K. (2009). A case of pleomorphic carcinoma with jejunum mesenterium metastasis. Japanese Journal of Lung Cancer, 49(2), 187-192. https://doi.org/10.2482/haigan.49.187

A case of pleomorphic carcinoma with jejunum mesenterium metastasis. / Yoshikawa, Akane; Naoki, Katsuhiko; Nitadori, Jun Ichi; Fujii, Tomoki; Okamoto, Hiroaki; Watanabe, Koshiro.

In: Japanese Journal of Lung Cancer, Vol. 49, No. 2, 04.2009, p. 187-192.

Research output: Contribution to journalArticle

Yoshikawa, A, Naoki, K, Nitadori, JI, Fujii, T, Okamoto, H & Watanabe, K 2009, 'A case of pleomorphic carcinoma with jejunum mesenterium metastasis', Japanese Journal of Lung Cancer, vol. 49, no. 2, pp. 187-192. https://doi.org/10.2482/haigan.49.187
Yoshikawa A, Naoki K, Nitadori JI, Fujii T, Okamoto H, Watanabe K. A case of pleomorphic carcinoma with jejunum mesenterium metastasis. Japanese Journal of Lung Cancer. 2009 Apr;49(2):187-192. https://doi.org/10.2482/haigan.49.187
Yoshikawa, Akane ; Naoki, Katsuhiko ; Nitadori, Jun Ichi ; Fujii, Tomoki ; Okamoto, Hiroaki ; Watanabe, Koshiro. / A case of pleomorphic carcinoma with jejunum mesenterium metastasis. In: Japanese Journal of Lung Cancer. 2009 ; Vol. 49, No. 2. pp. 187-192.
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